Magnetohydrodynamics plays a significant role in new development and future perspectives of clean energy power generation systems and flow control technology in the aeronautics, astronautics, plasma, and electrical conducting flow in the electric machinery. This paper examines the inherent irreversibility in an unsteady hydromagnetic Couette flow of a conducting variable viscosity fluid between two vertical parallel plates with thermal buoyancy and heat transfer characteristics. Necessary regulating model equations are obtained and then converted using dimensionless variables to form a set of nonlinear initial boundary valued problem. Employing a semi-discretization finite difference method known as the method of lines, the model is addressed numerically. The velocity and the temperature results obtained are used further to compute the entropy generation rate, the Bejan number, skin friction and Nusselt number. Some effects of the embedded parameters on the above-mentioned results are investigated and displayed by graphs. Our results revealed that entropy generation rate is enhanced with an upsurge in thermal buoyancy but a rise in magnetic field lessened it.