The feasibility of a neural network method was discussed in terms of a self-tuning proportional–integral–derivative (PID) controller. The proposed method was configured with two neural networks to dramatically reduce the number of tuning attempts with a practically achievable small amount of data acquisition. The first network identified the target system from response data, previous PID parameters, and response characteristics. The second network recommended PID parameters based on the results of the first network. The results showed that it could recommend PID parameters within 2 s of observing responses. When the number of trained data was as low as 1000, the performance efficiency of these methods was 92.9%, and the tuning was completed in an average of 2.94 attempts. Additionally, the robustness of these methods was determined by considering a system with noise or a situation when the target position was modified. These methods are also applicable for traditional PID controllers, thus enabling conservative industries to continue using PID controllers.