Self-rating Depression Scale Scores Research Articles

Study on the effect of internet plus continuous nursing on functional recovery and medication compliance of patients with knee joint replacement

ObjectiveTo evaluate the effect of "Internet + " continuity of care on postoperative functional recovery and medication compliance in patients with knee arthroplasty.MethodsIn this retrospective study, 100 patients who underwent knee replacement in our hospital between January 2021 and December 2022 were recruited and assigned to receive routine care (routine group) or "Internet + " continuity of care (continuity group), with 50 patients in each group. Outcome measures included knee function, sleep quality, emotional state, medication compliance, and self-care ability.ResultsPatients in the continuity group showed better knee function after discharge and during follow-up versus those in the routine group (P < 0.05). Continuity care resulted in significantly lower Pittsburgh Sleep Quality Index (PSQI), Self-Rating Anxiety Scale (SAS), and Self-Rating Depression Scale (SDS) scores versus routine care (P < 0.05). Patients in the continuity group showed higher treatment compliance, ability of daily living (ADL) scores, and nursing satisfaction than those in the routine group (P < 0.05).ConclusionThe "Internet + " continuity of care is highly feasible and can effectively promote the postoperative functional recovery of knee replacement patients, improve patients' medication compliance, sleep quality, and self-care ability, mitigate negative emotions, and provide enhanced home care.

Clinical study of analgesia in brachytherapy for cervical cancer

AbstractObjectiveThis study investigated the analgesic effects in patients with cervical cancer during brachytherapy.MethodsIn this prospective study, 100 patients with cervical cancer who were admitted to Chongqing University Cancer Hospital between July 2021 and April 2022 were randomly divided into an analgesia group (n = 50) and a control group (n = 50). The visual analog scale (VAS) scores at applicator placement‐T1, CT‐scan‐T2, and removal ‐T3, self‐rating anxiety scale (SAS) and self‐rating depression scale (SDS) scores before brachytherapy, short‐term clinical efficacy, and patient satisfaction were compared between the two groups.ResultsThe VAS score of the analgesia group was significantly different at T1 (0 vs. 4.34±1.02, t = 67.40, p &lt; 0.001), but not in the control group; however, there was no significant difference between the two groups at T2 (t = ‐0.49, p = 0.623) and T3 (t = ‐0.12, p = 0.912). The SAS and SDS scores first decreased and then increased in the analgesic group and increased in the control group with increasing brachytherapy time. Except for the first measurement, the differences between the two groups were statistically significant (all p &lt; 0.001). The application of interstitial implantation (p = 0.027), local efficacy (p = 0.047), and patient satisfaction rates (p = 0.025) were higher in the analgesic group than in the control group.ConclusionAnalgesia can relieve pain, maintain physical and mental health, and improve outcomes and patient satisfaction rates for cervical cancer.

RETN gene polymorphisms interact with alcohol dependence in association with depression.

Previous studies suggest that alcohol dependence is associated with increased risk of depression. The occurrence of depressive symptoms is related to polymorphisms in various genetic regions. This study aimed to investigate the interaction of RETN gene polymorphisms (rs1477341, rs3745368) with alcohol dependence on depressive symptoms in adult male during acute alcohol withdrawal. A total of 429 male adults were recruited in this study. Alcohol dependence was assessed using the Michigan alcoholism screening test (MAST). Depression was assessed using the 20-item self-rating depression scale (SDS). Hierarchical regression analysis was used to evaluate the interaction between genes and alcohol dependence on depression. Region of significance (ROS) test was used to explain the interaction effect. The strong and weak forms of the differential susceptibility and diathesis models were used to determine which fits the data better. Our results showed that MAST scores were significantly positively associated with SDS scores (r = 0.23, p < 0.01) in alcohol-dependent patients during alcohol withdrawal. The interaction between genotype and alcohol dependence was significant (β = -0.14, p < 0.05) in a strong diathesis-stress model. Susceptibility for depression symptoms was associated with alcohol dependence in RETN rs1477341 A carriers. Specifically, those that showed more alcohol dependence and the A allele of RETN rs1477341 exhibited more depression symptoms. However, RETN rs3745368 had no significant interaction with alcohol dependence. The A allele of RETN rs1477341 may correlate with susceptibility to depression symptoms in alcohol-dependent individuals during acute alcohol withdrawal.

Flexible nursing in patients with lung cancer who received chemotherapy.

Flexible nursing refers to the implementation of individualized nursing according to the patient's condition and characteristics, which can greatly alleviate patients' anxiety, depression and other adverse emotions and improve patients' nursing satisfaction. This experiment studies the effect of the implementation of flexible nursing model for patients with lung cancer chemotherapy. We enrolled a total of 107 patients with lung cancer who were admitted to Respiratory and Critical Care Medicine Department(East District) ofAnqing Municipal Hospital from November 2020 to May 2022 in the study. Patients were selected as per inclusion and exclusion criteria. We randomly divided the patients into the test group and control group using a random number table. Patients in the test group were given flexible nursing, while those in the control group received routine care. All patients completed the self-rating Anxiety Scale (SAS) score and Self-rating Depression Scale (SDS) score and calculated standard score before admission for chemotherapy, and completed the self-rating Anxiety Scale (SAS) score and self-rating Depression Scale (SDS) score and the Nursing Satisfaction Questionnaire of the Eastern Department of Respiratory and Critical Care Medicine of our hospital again at the time of discharge. The anxiety, depression and nursing satisfaction of the two groups before and after nursing were statistically analyzed. We statistically analyzed patients' anxiety and depression levels, as well as their appraisal of the nursing service. Compared to the scores obtained at the time of admission, the anxiety and depression scores significantly decreased for patients in both groups at the time of discharge (P < 0.05). Decrease in the anxiety and depression scores for the test group was significantly higher than that in the control group (P < 0.05). Patients in the test group reported significantly greater satisfaction with the nursing care when compared to the control group (P < 0.05). Flexible nursing can significantly decrease the anxiety and depression level in patients with lung cancer who receive chemotherapy and ensure more satisfactory nursing.

Mindfulness-based stress reduction combined with early cardiac rehabilitation improves negative mood states and cardiac function in patients with acute myocardial infarction assisted with an intra-aortic balloon pump: a randomized controlled trial.

To investigate the clinical effects of mindfulness-based stress reduction (MBSR) intervention combined with early cardiac rehabilitation (CR) on patients with acute myocardial infarction (AMI) assisted with an intra-aortic balloon pump (IABP). A total of 100 AMI patients with IABP assistance due to hemodynamic instability at Wuhan Asia Heart Hospital were enrolled in the study. The participants were divided into two groups using the random number table method (n = 50 each group). Patients receiving routine CR were assigned to the CR control group, while patients receiving MBSR plus CR were assigned to the MBSR intervention group. The intervention was performed twice a day until the removal of the IABP (5-7 days). Each patient's level of anxiety/depression and negative mood state were evaluated before and after intervention using the self-rating anxiety scale (SAS), self-rating depression scale (SDS), and profiles of mood state scale (POMS). The results of the control and intervention groups were compared. IABP-related complications and left ventricular ejection fraction (LVEF), measured with echocardiography, were also assessed and compared between the two groups. The SAS, SDS, and POMS scores were lower in the MBSR intervention group than in the CR control group (P < 0.05). There were also less IABP-related complications in the MBSR intervention group. LVEF was significantly improved in both groups, but the degree of LVEF improvement was more significant in the MBSR intervention group than in the CR control group (P < 0.05). MBSR combined with early CR intervention can assist in alleviating anxiety, depression, and other negative mood states, reduce IABP-related complications, and further improve cardiac function in AMI patients with IABP assistance.

Anxiety and depression among patients with non-tuberculous mycobacterial disease in Shanghai: a cross-sectional study.

To understand the mental health status and its influencing factors among patients with non-tuberculous mycobacterial disease and to provide a reference for medical staff to formulate scientific and feasible intervention strategies. A total of 114 patients diagnosed with non-tuberculous mycobacillosis during hospitalization in the Department of Infection from September 2020 to April 2021 were selected as the research participants. Participants' mental health status and related factors were evaluated using a self-made general patient information questionnaire, self-rating Anxiety Scale (SAS), and self-rating Depression Scale (SDS). Among 114 patients with non-tuberculous mycosis, 61 (53.51%) exhibited depressive symptoms, and the SDS score was 51.15 ± 13.04, which was higher than the national norm of 41.88 ± 10.57 (p < 0.05); further, 39 patients (34.21%) showed anxiety symptoms, and the SAS score was 45.75 ± 10.81, which was significantly higher than the national norm of 29.78 ± 10.07 (p < 0.05). Body mass index and monthly household income had significant effects on depression in patients with non-tuberculous mycobacterial disease (p < 0.05). Educational level had a significant effect on the anxiety state of patients with non-tuberculous mycobacterial disease (p < 0.05). Patients with non-tuberculous mycobacterial disease are prone to depression and anxiety. Nurses should pay attention to it in clinical work for the timely identification of and intervention for anxiety and depression and intervene.

Study of electroacupuncture with different frequencies for the treatment of headache and anxiety-depression symptoms in patients with migraine: A randomized clinical trial: 不同频率电针改善偏头痛患者头痛及焦虑抑郁症状的差异性研究-随机临床试验

: To observe the effects of electroacupuncture (EA) with varied frequencies on headache and anxiety-depression symptoms in patients with migraine and to screen optimal frequency of EA for patients with such conditions. : Single-center, randomized, controlled clinical trial was designed, and the outcome assessors and statisticians were blinded. The patients with migraine were randomized into 2 Hz EA group, 100 Hz EA group and sham-stimulation group. In each group, the changes in migraine attacks, days with headache, the scores of visual analogy scale (VAS), self-rating anxiety scale (SAS), self-rating depression scale (SDS) and migraine-specific quality-of-life questionnaire (MSQ), as well as the dosage of analgesics were observed at the baseline, during treatment, in 1, 2 and 3 months of follow-up separately. : Patients were enrolled in the Third Affiliated Hospital of Zhejiang Chinese Medical University, between 1st August 2018 and 31st July 2021. : Sixty-five migraine patients with or without aura. : In the EA groups, the acupoints were bilateral Fengchi (GB20), Gongxue (Extra), Sizhukong (TE23), Taiyang (EX-HN5), Shuaigu (GB8), Waiguan (TE5) and Yanglingquan (GB34). Electric stimulation was exerted at GB20 and Gongxue (Extra), with 2 Hz and 100 Hz separately. In the sham-stimulation group, the shallow acupuncture was operated at the sites 1 cm lateral to GB20 and Gongxue (Extra), and on the radial side of TE5 and GB34. The output wires were cut off after attached to the acupoints. The patients in each group received the treatment 3 times weekly, once every two days, for consecutive 4 weeks. The complete intervention was composed of 12 treatments. : Changes in numbers of migraine attacks at treatment phase (week 1 to week 4) from the baseline(week -4 to week 0) in patients of each group : (1) Changes in migraine attacks and days with headache: In the 2 Hz EA and 100 Hz EA groups, the changes for migraine attacks and days of headache were higher significantly when compared with that in the sham-stimulation group at the same time stage (P < 0.05). There was no statistical difference between two EA groups. (2) Changes of VAS score: In the 2 Hz EA and 100 Hz EA groups, the changes of VAS score were significantly higher when compared with that in the sham-stimulation group at the same time stage (P < 0.05). There was no statistical difference between two EA groups. (3) Assessment of anxiety and depression: The differences in the changes of SAS and SDS scores had no statistical significance in patients of each group at each assessment stage (P > 0.05). (4) Assessment on the quality of life: Compared with the sham-stimulation group at the same time stage, the improvement in MSQ score was increased significantly during treatment in patients of the 2 Hz EA group (P < 0.05). There was no statistical difference between two EA groups. (5) Assessment on safety and compliance: The patients of each group had sound compliance. There was no adverse events during trial, suggesting promising safety of treatment. : EA may effectively reduce the migraine attacks, and the days and intensity of headache, presenting promising safety. However, there was no significant improvement on anxiety-depression symptoms, and no significant difference between high and low frequencies of EA treatment in relieving headache and anxiety/depression symptoms in the patients with migraine. : ChiCTR1800017259

Association between breast nodules, anxiety, depression and metabolic risk factors in a Chinese cohort.

The relationship between anxiety, depression, and metabolic parameters and the incidence of breast nodules is unclear. This study aims to investigate the association between female breast nodules and anxiety, depression and metabolic factors. This cross-sectional study recruited 857 individuals with biological indicators and breast ultrasound data from the Daping hospital from April 2021 to February 2022. Serum samples were used to measure fasting blood glucose, uric acid, triglycerides, total cholesterol, urea nitrogen, alanine transaminase, aspartate transaminase, albumin, high-density lipoprotein, low-density lipoprotein. Self-rating anxiety scale (SAS) and self-rating depression scale (SDS) were used to assess the level of anxiety and depression. The positive rate of breast nodules in women aged 40 to 49 years old was significantly higher than that of other age women. The proportion of participants aged 40-49 years old in the group with breast nodules was significantly higher than that in the group without breast nodules (34.6% vs. 16.9%, p<0.001). Breast nodules in postmenopausal women were significantly lower than those in premenopausal women (26.4% vs. 73.6%, p = 0.026). The SAS scores of women with breast nodules were higher than those of the no-nodules group (40.99 ± 8.45 vs. 38.94 ± 6.89, p<0.001), same as the SDS scores (41.97 ± 10.33 vs. 38.91 ± 7.60, p < 0.001). The number of women suffering from anxiety in the group of breast nodules was significantly higher than that in control (13.8% vs. 4.5%, p < 0.001), and the number of depression in the group of breast nodules was also significantly higher than that of in control (14.4% vs. 4.5%, p < 0.001). Women with breast nodules showed a slightly lower uric acid level than those without breast nodules (290.11 ± 65.32 vs. 301.43 ± 65.93 umol/L, p = 0.016). Multivariable logistic regression analysis showed that age, menopausal status, anxiety and depression status were significantly associated with the presence of breast nodules, but there was no significant difference in uric acid. Our findings offer insight into the occurrence of depression and anxiety in the breast nodules of Chinese women. Anxiety and depression status, age and menopausal status may be the independent risk factors for the occurrence of breast nodules.

Effect of treatment with benzathine penicillin combined with ceftriaxone in elderly patients with latent syphilis

Purpose: To investigate the effect of the combination of benzathine penicillin and ceftriaxone in the treatment of latent syphilis in the elderly. &#x0D; Methods: A total of 70 elderly patients with latent syphilis treated in the First People’s Hospital of Yichang from March 2020 to March 2021 were enrolled in this study. Control group (CG) comprised thirty-two patients treated with benzathine penicillin, while 38 patients received the combination of benzathine penicillin and ceftriaxone were placed in the study group (SG). Therapeutic efficacy and adverse reactions in both groups were assessed. The difference in toludine red unheated serum test (TRUST) negative conversion rate at different periods of treatment (3, 6, and 12 months) after treatment was observed. Dermatological quality of life index (DLQI), self-rating anxiety scale (SAS) and self-rating depression scale (SDS) scores were also determined before and after treatment. &#x0D; Results: Total efficacy in the study group was significantly higher than that in the control group after treatment (p &lt; 0.05), but there was no significant difference in the total incidence of adverse reactions between both groups (p &gt; 0.05). The TRUST negative conversion rate at 6 and 12 months in SG was higher than that in CG (p &lt; 0.05), while DLQI, SAS and SDS scores in SG were significantly lower after treatment (p &lt; 0.05). &#x0D; Conclusion: Treatment of elderly patients with latent syphilis with the combination of benzathine penicillin and ceftriaxone effectively controls the disease and improves patients’ negative emotions and quality of life with few adverse drug reactions. Further clinical trials are required prior to application in clinical practice.

Application effect of prehospital-hospital integrated emergency nursing in patients with acute cerebral infarction

ABSTRACT This investigation aimed to elucidate the application impact of prehospital-hospital integrated emergency nursing in individuals with acute cerebral infarction (ACI). Data of 230 ACI patients admitted to our hospital from May 2021 to July 2022 were retrospectively analyzed and divided into A and B groups (AG and BG) according to different nursing methods. The inter-group comparison of the treatment time (time for physician arrival, time for completion of examination, time between admission and thrombolytic therapy, length of stay in emergency) was compared. The success rate of thrombolysis, the inter-group comparison levels of coagulation function indexes [D-dimer (D-D) and fibrinogen (Fbg)], the national Institutes of Health Stroke Scale (NIHSS) score, the Barthel score, family members’ self-rating anxiety scale (SAS) score, family members’ self-rating depression scale (SDS) score, family satisfaction and adverse reactions were compared between the two groups. The treatment time were reduced in the BG than in the AG (all P < 0.05). The BG had a higher success rate of thrombolysis than the AG (P < 0.05). After the therapy, the D-D level in BG group was higher than that in AG group, and Fbg was lower than that in AG group (both P < 0.05). After nursing, BG’s NIHSS score was increased compared with the AG; MBI was reduced (P < 0.05); the SAS and SDS scores of the family members were also reduced (both P < 0.05). The total family satisfaction of the BG (100.00%) was greater than the AG (89.00%) (P < 0.05). The application of prehospital-hospital integrated emergency nursing in ACI patients works effectively.

Impact of COVID Pandemic on the Mental State of Health Workers: A Study of Mindfulness-based Interventions

Background: An increasing number of studies have been conducted on the prevalence of COVID-19 to develop strategies to combat the disease. However, less attention has been paid to the mental health of medical professionals. Objectives: To investigate whether a mindfulness-based stress reduction (MBSR) course in Tibet could improve the mental health of medical personnel during the COVID-19 epidemic. Methods: One hundred and eighteen medical staff were randomly selected from July 2022 to September 2022. After baseline enrolment, the control group (n=59) received baseline healthcare services, while the intervention group (n=59) received a 2-month positive intervention MBSR course in addition to baseline healthcare services. After the intervention, the intervention group underwent a final assessment, and the control group was subjected to MBSR for 2 months. The Self-Rating Depression Scale (SDS), Self-Consciousness Scale (SCS), and the Chinese version of the Cohen Perceived Stress Scale (CPSS) were used to measure the emotional well-being of medical personnel. Results: The intervention group had significantly lower CPSS and SDS scores at the end of the MBSR course (P&lt;0.01), and SCS scores were significantly increased during M2 (P=0.009), compared to M0. In the control group, the scores of SDS (P=0.223), SCS (P=0.112), and CPSS (P=0.131) in M2 were not significantly different from those in M0. The intervention and control groups showed statistically significant differences in CPSS scores (P=0.013), SDS scores (P=0.001), and SCS scores (P=0.029) at the end of the MBSR session. Conclusion: It can be concluded that MBSR sessions can effectively alleviate negative emotions triggered by work stress and depression and improve self-compassion during an epidemic. It is recommended to participate in a scientific MBSR course to improve emotional well-being to some extent.

Pain mediates the improvement of social functions of repeated intravenous ketamine in patients with unipolar and bipolar depression

ObjectivePrevious research has shown that ketamine can improve social functions. In addition, evidence also suggests that ketamine can alleviate pain. Herein, we propose that ketamine-induced improvements in pain and depression are partially mediated by a reduction in pain. We aimed to determine whether improvements in pain-mediated changes in psychological function were associated with ketamine treatment. MethodThis trial included unipolar or bipolar patients (n = 103) who received 6 intravenous infusions (0.5 mg/kg) of ketamine over 2 weeks. The severity of current depressive symptoms and social function were evaluated by the Montgomery-Åsberg Depression Scale (MADRS), Self-Rating Depression Scale (SDS) and Global Assessment Function (GAF), respectively, at baseline and on day 13 and day 26. At the same time points, the three dimensions of pain, including the sensory index, affective index and present pain intensity (PPI), were measured by the Simple McGill Pain Scale (SF-MPQ). ResultsThe mixed model results showed that ketamine plays an important role in improving the psychosocial functioning of patients. There was a significant decrease from baseline to the day 13 and day 26, indicating that the pain index of the patient improved significantly. Mediation analysis showed that for SDS score (coef = −5.171, 95 % CI[−6.317, −4.025]) and GAF score (coef = 1.021, 95 % CI[0.848, 1.194]), the overall effect of ketamine was observable. The overall indirect and direct effects of ketamine on social functioning were significant (SDS: direct: coef = −1949 to −2114; total indirect: from 0.594 to 0.664; GAF: from 0.399 to 0.427; total indirect: coef = 0.593 to 0.664). The MADRS total score and emotional index were important mediators of the association between ketamine treatment and improvements in subjective and objective social functioning. ConclusionDepressive symptom severity and the affective index of pain partially mediated improvements in social function after six repeated ketamine treatments among patients with bipolar or unipolar depressive disorder.

The effect of a modified perioperative management model on the mental state, quality of life, and self-care ability score of patients after radical prostatectomy: A retrospective study.

To explore the effects of an improved perioperative management model on the mental state, quality of life, and self-care ability scores of patients after radical prostatectomy. Overall, 96 postoperative prostate cancer patients admitted to our hospital between November 2019 and May 2021 were retrospectively analyzed and classified into an observation group and a control group with 48 patients each, according to the management model they received. The patients in the control group received routine care and were discharged. The observation group implemented an improved perioperative management model than the control group. Differences in mental state, quality of life, and self-care ability scores between the 2 groups were compared. After nursing, the self-rating anxiety scale and self-rating depression scale scores of the 2 groups were significantly lower than those before nursing, and the observation group's self-rating anxiety scale and self-rating depression scale scores were significantly lower than those of the control group (P < .05). Regarding emotion, cognition, and society, the observation group's quality of life scores was significantly higher than those of the control group. In contrast, overall health was significantly lower than that of the control group (P < .05). After nursing, the observation group's self-care skills, self-responsibility, health knowledge, and self-concept scores were significantly better than those of the control group (P < .05). The improved prostate cancer perioperative management model helps improve patients' unhealthy mental state, quality of life, self-care ability, and provides guidelines for the clinical care of patients after prostate cancer surgery.

Associations between anxiety, depression with migraine, and migraine-related burdens.

Anxiety and depression are the most common psychiatric comorbidities in migraine, but their impact on the risk of developing migraine and their gender and age differences are unclear, and research on their associations with migraine-related burdens are limited. To systematically explore the association between anxiety and depression with migraine and migraine-related burdens, including the risk of developing migraine, as well as migraine frequency, severity, disability, headache impact, quality of life and sleep quality. A total of 170 migraineurs and 85 sex-and age-matched healthy control subjects were recruited consecutively for this study. Anxiety and depression were assessed using Zung's Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS), respectively. Logistic regression and linear regression analyses were used to explore the associations between anxiety and depression with migraine and its burdens. The receiver operating characteristic (ROC) curve was used to evaluate the predictive value of SAS score and SDS score on migraine and its severe burdens. After adjusting for confounders, anxiety and depression remained significantly associated with an increased risk of developing migraine, with odds ratios of 5.186 (95% CI:1.755-15.322) and 3.147 (95% CI:1.387-7.141), respectively. Meanwhile, there were significant additive interactions between the association of anxiety and depression with the risk of developing migraine in gender and age (P for interaction <0.05), and the stronger correlations were found in participants with an age ≤ 36 years old and females. In addition, anxiety and depression were significantly independently associated with the migraine frequency, severity, disability, headache impact, quality of life, and sleep quality in migraine patients (P trend <0.05). The area under the ROC curve (AUC) of SAS score in predicting developing migraine was significantly higher than that of SDS score [0.749 (95% CI: 0.691-0.801) vs. 0.633 (95% CI: 0.571-0.692), p < 0.0001]. Anxiety and depression were significantly independently associated with the increased risk of migraine and migraine-related burdens. Enhanced assessment of SAS score and SDS score is of great clinical value for the early prevention and treatment of migraine and its burdens.

Quality of life after tongue cancer treatment and its influencing factors: A cross‐sectional study of Japanese patients

AbstractAimThe post‐treatment quality of life (QOL) of patients with cancer has become an important issue owing to significant improvements in the outcomes of cancer treatment. The oral cavity has not only life‐sustaining functions but also important social functions, including talking. Thus, many reports have assessed the post‐treatment QOL of patients with oral cancer. However, the sample sizes in most studies were insufficient to control for potential confounding variables. Additionally, previous studies have indicated that racial/ethnic differences may be associated with health‐related QOL. Thus, this study aimed to clarify factors influencing post‐treatment QOL using multiple regression analysis in a large number of Japanese patients with tongue cancer.MethodsIn total, 106 patients with tongue cancer were recruited from the oral surgery departments of three university hospitals sharing a common treatment plan for tongue cancer. QOL was evaluated using the University of Washington Quality of Life Questionnaire, and depressive tendencies were assessed using the Self‐rating Depression Scale (SDS).ResultsNeck dissection was most widely associated with physical and socio‐emotional QOL. Reconstruction, radiotherapy, and higher T‐stage and SDS scores were the second most widely associated factors with QOL. Interestingly, a higher SDS score was negatively related only to socio‐emotional factors. Furthermore, only SDS scores were associated with the general QOL.ConclusionThis study suggested that the physical and socio‐emotional QOL was widely affected by neck dissection, reconstruction, radiotherapy, T‐stage, and SDS scores, whereas the general QOL was affected only by SDS scores. These findings should be considered when treating patients with oral cancer.

Study on the value of KMC combined with blue light irradiation in improving the therapeutic effect of neonatal jaundice

ABSTRACT Neonatal jaundice is a common problem that affects newborns. We aim to investigate the effect of Kangaroo Mother Care (KMC) combined with blue-light irradiation on enhancing the therapeutic effect in the treatment of neonatal jaundice. From May 2020 to August 2022, 89 neonates with pathological jaundice and their mothers were selected as participants. All neonates received blue-light irradiation. The participants were divided into two groups: 46 neonates cared for by KMC as the research group (RG) and 43 neonates receiving routine nursing as the control group (CG). The first lactation time, first breastfeeding duration, and scores of Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) before and after nursing were recorded and compared between the groups. Pre- and post-interventional total bilirubin (TBIL), direct bilirubin (DBIL), and indirect bilirubin (IBIL) levels of both groups of newborns were measured, and the time of jaundice resolution, first defecation, and meconium yellowing were recorded. Neonatal adverse reactions (ARs) during treatment were counted, and a nursing satisfaction survey was conducted at discharge. KMC group mothers had earlier lactation and longer first breastfeeding durations (P < 0.05). Both groups’ SAS and SDS scores decreased post-nursing, with greater improvement in the KMC group (P < 0.05). KMC group newborns had lower bilirubin levels and faster resolution of jaundice and meconium yellowing, with fewer adverse reactions and higher nursing satisfaction (P < 0.05). KMC can effectively improve the efficacy of blue light irradiation in the treatment of neonatal jaundice, and promote the healthy development of newborns and the efficiency of maternal breastfeeding.

Linear Regression Analysis of Sleep Quality in People with Insomnia in Wuhan City during the COVID-19 Pandemic.

COVID-19 has evolved into a major global public health event. The number of people reporting insomnia is growing exponentially during the pandemic. This study aimed to explore the relationship between aggravated insomnia and COVID-19-induced psychological impact on the public, lifestyle changes, and anxiety about the future. In this cross-sectional study, we used the questionnaires from 400 subjects who were obtained from the Department of Encephalopathy of the Wuhan Hospital of Traditional Chinese Medicine between July 2020 and July 2021. The data collected for the study included demographic characteristics of the participants and psychological scales consisting of the Spiegel Sleep Questionnaire, the Fear of COVID-19 Scale (FCV-19S), the Zung Self-Rating Anxiety Scale (SAS), and the Zung Self-Rating Depression Scale (SDS). The independent sample t-test and one-way ANOVA were used to compare the results. Correlation analysis of variables affecting insomnia was performed using Pearson correlation analysis. The degree of influence of the variables on insomnia was determined using linear regression, and a regression equation was derived. A total of 400 insomnia patients participated in the survey. The median age was 45.75 ± 15.04 years. The average score of the Spiegel Sleep Questionnaire was 17.29 ± 6.36, that of SAS was 52.47 ± 10.39, that of SDS was 65.89 ± 8.72, and that of FCV-19S was 16.09 ± 6.81. The scores of FCV-19S, SAS, and SDS were closely related to insomnia, and the influencing degree was in the following order: fear, depression, and anxiety (OR = 1.30, 0.709, and 0.63, respectively). Fear of COVID-19 can be one of the primary contributors to worsening insomnia.

The Situation and Influencing Factors of Depression and Anxiety in Patients of Hemodialysis during the COVID-19 Pandemic in China.

To investigate the incidence of depression and anxiety among maintenance hemodialysis (MHD) patients during the regular prevention and control stage of COVID-19 in China as well as the influencing factors. A cross-sectional study including 180 patients under the treatment of hemodialysis was conducted in the hemodialysis center of the 8th Affiliated Hospital of Sun Yat-Sen University. The questionnaire regarding the subject's general information, Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) was completed by the patients, and the laboratory test results were recorded. The incidences of anxiety and depression were 35.6% and 38.9%, respectively, and the average scores of SAS and SDS were (48.03 ± 5.02) and (48.12 ± 5.42), respectively, in the subjects. The results showed that age, monthly income, vascular access of dialysis, feeling of pain and itching (within a week), worried about being infected by COVID-19, whether having health insurance and the levels of hemoglobin, parathyroid hormone, and phosphorus were the impact factors of both anxiety and depression in the MHD patients (p < 0.05 for all). The proportion of depression and anxiety is relatively high in the MHD patients during the regular prevention and control stage of COVID-19.

Study on the effect of intervention on postpartum psychological improvement and body recovery of caesarean section women based on information-motivation-behavioural skills model.

To explore the effect of information-motivation-behavioural skills (IMB) model on psychological and emotional state of caesarean section (CS) women. Control-group patients got routine nursing during the preoperative, intraoperative and postoperative periods. Observation-group patients received routine nursing combined with the IMB model that included specific informational, motivational and behavioural interventions. Pregnant women (n= 102) who underwent CS in Hangzhou Women's Hospital were randomly divided into Control and Observation-groups (n= 51 each). Self-rating anxiety scale (SAS), self-rating depression scale (SDS) and general self-efficacy scale (GSES) scores, complication rate, fatigue severity scale (FSS) and Edinburgh postpartum depression scale (EPDS) scores were compared. Interventions lowered SAS and SDS scores, significantly lower in the Observation-group (p< 0.05), and increased GSES scores, significantly higher in the Observation-group (p< 0.05). Observation-group had less complications (4.08% vs. 17.39% in the Control-group; p< 0.05), and decreased FSS and EPDS scores (p< 0.05).

Resting-State EEG Reveals Abnormal Microstate Characteristics of Depression with Insomnia.

Previous research revealed various aspects of resting-state EEG for depression and insomnia. However, the EEG characteristics of depressed subjects with insomnia are rarely studied, especially EEG microstates that capture the dynamic activities of the large-scale brain network. To fill these research gaps, the present study collected resting-state EEG data from 32 subclinical depression subjects with insomnia (SDI), 31 subclinical depression subjects without insomnia (SD), and 32 healthy controls (HCs). Four topographic maps were generated from clean EEG data after clustering and rearrangement. Temporal characteristics were obtained for statistical analysis, including cross-group variance analysis (ANOVA) and intra-group correlation analysis. In our study,the global clustering of all individuals in the EEG microstate analysis revealed the four previously discovered categories of microstates (A, B, C, and D). The occurrence of microstate B was lower in SDI than in SD and HC subjects. The correlation analysis showed that the total Pittsburgh Sleep Quality Index (PSQI) score negatively correlated with the occurrence of microstate C in SDI (r=- 0.415, p < 0.05). Conversely, there was a positive correlation between Self-rating Depression Scale (SDS) scores and the duration of microstate C in SD (r = 0.359, p < 0.05). These results indicate that microstates reflect altered large-scale brain network dynamics in subclinical populations. Abnormalities in the visual network corresponding to microstate B are an electrophysiological characteristic of subclinical individuals with symptoms of depressive insomnia. Further investigation is needed for microstate changes related to high arousal and emotional problems in people suffering from depression and insomnia.