Abstract Background Simulation training has proved to be beneficial in many fields of professions including medicine and might be included already during medical school. Aims We evaluated if medical students rate their manual dexterity as good or above average and if this self-assessment (SA) correlates with the actual performance in a surgical simulation. Methods Basic surgical tasks have been performed by medical students in the 3rd and 4th year for a total of 4 rounds on 2 identical Lap-Sim® surgical simulators. Three questionnaires, before and after the simulation as well as follow up after 1 year had to be answered. Descriptive statistics stratified by career goal (surgical/ undecided/ nonsurgical) for outcomes of simulation parameters are reported. Associations between surgical career goal and SA of manual dexterity with three performance parameters (tissue damage, time and path length) are estimated in linear regression models. Results Out of 102 participating students 41 stated surgery as their career goal, 18 a nonsurgical field, and 43 were undecided. 87.8% of the surgical group rated their dexterity as good or above average (86.1% in the undecided group), 88.9% of the nonsurgical group as below average or good. A positive association of SA with tissue damage has been found statistically significant (p=0.033). One year after the simulation (n=97) 13.4% changed their career goal from undecided to surgical, whereas 8.2% changed from undecided to non-surgical. 92.7% wanted to have simulation training integrated into the curriculum. Conclusion A correlation of self-assessed manual dexterity has been found in the surgical group for tissue damage, but not for time and path length. Simulation training might help students in decision making for a surgical field and therefore recruit future surgeons, which could be shown in the one-year follow-up.