Levels Of Selenium Supplementation Research Articles

Effect of graded levels of selenium supplementation as selenite on expression of selenosugars, selenocysteine, and other selenometabolites in rat liver.

Using high pressure liquid chromatography (HPLC) coupled with selenium-specific inductively coupled plasma mass spectrometry (ICP-MS) and molecule specific (Orbitrap MS/MS) detection, we previously found that far more selenium (Se) is present as selenosugar (seleno-N-acetyl galactosamine) in Se-adequate turkey liver than is present as selenocysteine (Sec) in true selenoproteins, and that selenosugars account for half of the Se in high-Se turkey liver. To expand these observations to mammals, we studied Se metabolism in rats fed graded levels of selenite from 0 to 5μg Se/g for 4 wk. In Se-adequate (0.24μg Se/g) rats, 43% of liver Se was present as Sec, 32% was present as selenosugars, and 22% as inorganic Se bound to protein. In liver of rats fed 5μg Se/g as selenite, the quantity of Sec remained at the Se-adequate plateau (11% of total Se), 22% was present as low molecular weight (LMW) selenosugars with substantial additional selenosugars linked to protein, but 64% was present as inorganic Se bound to protein. No selenomethionine was found at any level of selenite supplementation. Below the Se requirement, Se is preferentially incorporated into Sec-selenoproteins. Above the dietary Se requirement, selenosugars become by far the major LMW water soluble Se species in liver, and levels of selenosugar-decorated proteins are far higher than Sec-selenoproteins, making these selenosugar-decorated proteins the major Se-containing protein species in liver with high Se supplementation. This accumulation of selenosugars linked to cysteines on proteins or the build-up of inorganic Se bound to protein may underlie Se toxicity at the molecular level.

Selenium supplementation levels and sources in postlarvae Nile tilapia diet

Fish larviculture exert great influence in the subsequent phases, in which nutrition is a basic prerequisite for success. Therefore, when it is in an intensified production system, it promotes the limitation of some minerals, making it necessary to supplement selenium in diets for post-larvae. The objective of this study was to evaluate selenium levels and sources in post-larvae Nile tilapia diets on muscle performance and histology. A total of 1,260 post-larvae with an initial average weight of 0.010 g were used, distributed in a completely randomized design in a factorial scheme with four supplementation levels (0.6; 0.9; 1.2 and 1.5 mg of Se/Kg) and two sources (sodium selenite and selenium yeast), plus the negative control, with 35 post-larvae Nile tilapia used per experimental unit. The physical-chemical parameters of water quality were within those recommended for tilapia cultivation. Feed consumption (p < 0.05) and hepatosomatic index (p < 0.05) were affected by the source used. Effects of supplemented selenium levels and sources were not observed for the other performance variables. Higher values for final height, final width, specific development rate and protein efficiency rate were found (p < 0.05) when comparing the control diet with diets containing the sodium selenite source. No effects on muscle fiber morphometry were observed (p > 0.05) in the studied variables. It is concluded that 0.6 mg of selenium in the diet, regardless of the source used, met the mineral requirement for post-larvae Nile tilapia.

SELENIUM AND VITAMIN E SUPPLEMENTATION OF HIGH N-ALKANE GROWN YEAST IN CHICK DIETS

A total of four experiments have been conducted to evaluate performance of chicks given high (300/kg diet) n-alkane grown yeast diet supplemented with vitamin E and selenium. Four levels (0,10,20,30 mg) of vitamin E were examined in experiment 1 while five levels (0,12.5,15.0,17.5,20mg) were examined in experiment 2. Performance was also measured at four selenium supplementation levels (0, 50,100, 150 µg Se/kg diet) initially and finally at five other (0,100, 125, 150, 175 µg/kg diet) more detailed levels. Supplementation of a 300g/kg yeast diet with 15mg Vitamin E produced significantly (P < 0.05) higher body weight than unsupplemented high yeast diet. Higher levels produced no further growth response. At this level of vitamin E supplementation every level of selenium examined gave significant (P < 0.05) increase in weight but optimum growth response was obtained at 100µg Se/kg yeast diet. There were no significant treatment effects on feed intake at all levels of vitamin E and selenium examined. Nitrogen retention also showed no response at the highest levels (100 - 157µg) of selenium supplementation. The results show that supplementation with appropriate levels of vitamin E and selenium significantly reduced the depression in growth rate caused by high levels of inclusion of n-alkane grown yeast in chick diet.

Effect of organic selenium dietary supplementation on quality and fertility of cryopreserved chicken sperm

Oxidative stress due to cryopreservation has been considered as a major factor in sperm damage. Supplementation of the diet with different concentrations of organic selenium has been proposed to improve the quality of fresh and frozen–thawed semen in different breeds of roosters. Sixteen Pradu Hang Dum (Thai native) and 16 Rhode Island Red roosters were used in this study. Four levels of selenium supplementation between 0 and 0.9 ppm were examined. After 14 days of feeding, semen samples were collected twice a week and the fresh semen was evaluated. Then semen from each group was pooled and cryopreserved. The fertility of frozen–thawed semen was determined by inseminating 48 layer hens. Supplementation of diets with 0.3, 0.6 and 0.9 ppm selenium improved the fresh semen in terms of sperm viability and normal morphology (P < 0.01). Sperm concentration increased (quadratically, P < 0.001) with increasing dietary selenium levels. Meanwhile, post-thawed semen quality in terms of sperm motility, viability, live with intact acrosome and functioning mitochondria improved significantly with selenium treatments of 0.6 and 0.9 ppm, and lipid peroxidation was decreased (P < 0.001) and fertility improved (P < 0.05) with those levels of selenium treatment. In addition, there were differences between breeds with respect to some fresh or frozen semen quality parameters (P < 0.05). In conclusion, the breed affected both fresh and frozen semen. Even there were no statistically significant differences in the parameters from groups 0.6 and 0.9 ppm on frozen-thawed semen quality, but the highest sperm concentration was found in 0.6 ppm. Therefore selenium supplementation of diets at 0.6 ppm was recommended to improve the quantity and quality of fresh and frozen semen.

Simultaneous detection of the enzyme activities of GPx1 and GPx4 guide optimization of selenium in cell biological experiments

Selenium is a metalloid trace element essential for maintaining the optimal redox environment in cells and tissues. It is structurally incorporated into over 25 selenoproteins and enzymes. The glutathione peroxidase (GPx) family of enzymes has a critical role in human health because of its antioxidant function. The recommended daily allowance (RDA) for selenium intake in humans was established to maximize the activity of GPx in plasma. Suboptimal availability of selenium can limit the expression and activities of GPxs leading to a compromised redox environment. This can cause detrimental oxidative distress that could be prevented by increasing the availability of selenium. In cell culture studies, the medium is typically deficient in selenium; supplementation with selenium can increase selenoenzyme activities. However, the optimal level of supplementation in cell culture media has not been well characterized. We performed dose-response experiments for the activities of GPx1 and GPx4 vs. the level of selenium supplementation in cell culture medium. For this, we advanced an assay to determine the activities of both GPx1 and GPx4 efficiently in a single run. During the optimization process, we found that the observed activities of GPx1 and GPx4 depend greatly on the pH of the assay buffer; the observed activities increase with increasing pH, with pH 8 being optimal. Using the combination assay, we also found that the expression and activities for both GPx1 and GPx4 can be maximized in exponentially growing cells by supplementing cell culture media with ≈ 200 nM seleno-l-methionine, without concerns for toxicity. Optimizing the availability of selenium in cell culture to maximize the expression and activities GPx1 and GPx4 may allow for better translation of information from cell culture work to in vivo settings.

Effect of varied levels of selenium supplementation in nano form on growth, nutrient intake and digestibility in Wistar albino rats

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Effect of varied levels of selenium supplementation in nano form on growth, nutrient intake and digestibility in Wistar albino rats

Sixty three weaned male Wistar albino rats (124.3±3.1 g mean body weight) were divided into 9 treatment (T) groups following completely randomized design (CRD) and fed a common basal diet except for selenium (Se) source and levels. While in T1 (control), no Se was supplemented; in T2 and T3, 150 ppb Se was supplemented as nano Se and sodium selenite, respectively. The rats in T4, T5, T6 and T7 were supplemented nano Se at 75, 37.5, 18.75 and 9.375 ppb levels respectively. The rats in T8 and T9 were supplemented 300 ppb Se as nano Se and sodium selenite respectively. The experimental feeding lasted for a period of 13 weeks including a digestion trial of 5 days after 40 days of experimental feeding. The intake and digestibility of DM, OM, EE, CF, NFE and CP were similar (P>0.05) among different treatment groups, however CP digestibility was significantly (P 0.05) among the nine groups. The apparent Se absorption was significantly (P<0.001) higher in T3 supplemented with 150 ppb nano Se. The average daily gain (ADG) was significantly (P<0.05) higher and feed: gain ratio was significantly (P<0.05) lowered in T3 supplemented with 150 ppb nano Se. The results suggested that nano Se supplementation up to 300 ppb had no adverse effect on growth, nutrient intake and digestibility in male Wistar albino rats and nano Se supplementation at 150 ppb exerted a positive effect on growth, protein utilization and apparent selenium absorption in male Wistar albino rats.

Influence of organic vs inorganic source and different dietary levels of selenium supplementation in diets for growing pigs on meat quality

Influence of organic vs inorganic source and different dietary levels of selenium supplementation in diets for growing pigs on meat quality

Effect of Different Selenium Supplementation Levels on Oxidative Stress, Cytokines, and Immunotoxicity in Chicken Thymus.

This study assessed the effects of different selenium (Se) supplementation levels on oxidative stress, cytokines, and immunotoxicity in chicken thymus. A total of 180 laying hens (1day old; Mianyang, China) were randomly divided into 4 groups (n = 45). The chickens were maintained either on a basic diet (control group) containing 0.2mg/kg Se, a low-supplemented diet containing 5mg/kg Se, a medium-supplemented diet containing 10mg/kg Se, or a high-supplemented diet containing 15mg/kg Se for 15, 30, and 45days, respectively. Over the entire experimental period, serum and thymus samples were collected and used for the detection of the experimental index. The results indicated that the antioxidative enzyme activities and messenger RNA (mRNA) levels of antioxidative enzymes, IFN-γ and IL-2 in the thymus, and the content of IFN-γ and IL-2 in the serum of excessive-Se-treated chickens at all time points (except for the 5mg/kg Se supplement group at 15days) were significantly decreased (P < 0.05) compared to the corresponding control groups. Interestingly, a significantly increase (P < 0.05) in the content of IFN-γ was observed in the serum and thymus in the 5mg/kg Se supplement group at 15 and 30days compared to the corresponding control groups. In histopathological examination, the thymus tissue from excessive-Se-treated chickens revealed different degrees of cortex drop, incrassation of the medulla, and degeneration of the reticular cells. These results suggested that the excessive Se could result in a decrease in immunity, an increase in oxidative damage, and a series of clinical pathology changes, such as cortex drop, incrassation of the medulla, and degeneration of the reticular cells.

Selenium balance in the adult cat in relation to intake of dietary sodium selenite and organically bound selenium

The response of cats to dietary sodium selenite (Na(2) SeO(3)) and organically bound selenium was studied in two separate studies with four cats per treatment and three levels of selenium supplementation (targets 1.0, 1.5 and 2.0 μg/g DM) for each Se source. Whole blood and plasma selenium concentrations and glutathione peroxidase (GPx) activity were determined at 7-time points across the 32-day study. Faeces were quantitatively collected during the last 8 days and urine was collected daily during both studies. The basal diet used had a low apparent faecal selenium absorption of 25.3 ± 3.0%. Daily faecal and urinary selenium excretion increased linearly with increasing selenium intake for both Se sources. Urinary selenium concentration of the cats fed the supplemented diets increased rapidly (∼2 days) and remained constant throughout the remainder of the study. Apparent faecal selenium absorption was high for both selenium sources (73.2% and 80.0%). Plasma, and to a lesser extent, whole blood selenium concentrations increased in a dose-dependent manner with supplementation. Whole blood and plasma GPx activity were highly variable and showed a variable response to dietary selenium intake. Cats closely regulate selenium homeostasis through increasing urinary excretion whilst faecal absorption remains unaffected.

Effects of selenium diets on growth, accumulation and antioxidant response in juvenile carp

An 8-week feeding trial was undertaken with Cyprinus carpio to determine the effects of two commercial Se diets (HSe 1.0 mg kg −1 and LSe 0.25 mg kg −1) on growth, accumulation and antioxidant response in juveniles at time 0, 30 and 60 days. HSe carp had higher mean weight ( W) values than LSe group at 60 days and the Fulton condition factor ( K) indicated good fish health for both diet groups. Among the investigated HSe tissues, kidney and liver were mainly involved in Se accumulation, whereas the Se level in muscle indicated a very low Se contamination risk for human health. Selenium accumulation levels in HSe tissues followed this order: kidney>liver>muscle. Although growth was not impaired, biochemical antioxidant indicators in liver and kidney evidenced an oxidative stress condition in HSe juveniles. Furthermore, selenium supplementation levels, higher than the one employed in this study, might worsen the antioxidant status of carp.

Effect of crude protein levels and organic selenium supplementation in the diets fed during the breeding season on reproductive parameters of red-winged tinamous (Rhynchotus rufescens)

There is little information on the nutrition of red-winged tinamous (Rhynchotus rufescens) reared in captivity, and their nutritional requirements still need to be determined. This study aimed at determining dietary crude protein requirements and testing four organic selenium supplementation levels in the diet of red-winged tinamous during the breeding season. Birds were housed in a conventional broiler house divided in 16 boxes with one male and three females each. Iso-energy (2800kcal ME/kg) pelleted feeds, based on corn and soybean meal, were supplied in tube feeders. In the first experiment, treatments consisted of four different diets containing different crude protein (CP) contents (15, 18, 21, or 24%) and in the second experiment, the four diets contained equal protein level (22.5%) and four different organic selenium levels (0, 0.2, 0.4, or 0.8ppm). Data were analyzed by the least square method. The best egg weight and eggshell thickness were obtained with 22.5% dietary CP. Organic selenium did not influence the studied reproductive traits of red-winged tinamous (Rhynchotus rufescens) males or females.

The Effect of Level and Source of Dietary Selenium Supplementation on Eggshell Quality

A 16-week-long experiment was performed to compare the effect of sodium selenite (SS) and selenium-enriched yeast (SY) supplementation on eggshell quality and also to evaluate breaking force correlation with other parameters of shell quality originating from hens fed with selenium supplementation. One hundred Shaver 579 hens (27 weeks old) with similar body size were randomly divided for five dietary treatments: basal diet without selenium supplementation and basal diets with two levels of selenium supplementation (0.4 or 0.8 mg/kg) via SS or SY. No adverse effect of Se inclusion in hen's feed, regardless of its source, on shell breaking force, shell deformation, shape index, shell thickness and shell percentage, were observed throughout the current study (P > 0.05). Moderate correlations were found between breaking force and nondestructive shell deformation for all diets (P < 0.05). There was no significant overall correlation between egg breaking force and shell thickness or/and percentage shell in the presence of selenium supplementation (P > 0.05). Shape index in all four selenium-supplemented groups was not related to the breaking force (P > 0.05). Selenium supplementation of up to 0.8 mg/kg, regardless of its source, in the diet of laying hens in their first phase of laying does not adversely affect eggshell quality.

Effect of Different Levels of Selenium Supplementation on Growth Rate, Nutrient Utilization, Blood Metabolic Profile, and Immune Response in Lambs

Eighteen male lambs (8-9 months of age, 25.00 +/- 0.90 kg body weight) were divided into three groups of six animals in each and fed a total mixed ration (TMR) containing concentrate mixture (30% maize grain, 27% soybean meal, 40% wheat bran, 2% mineral mixture, and 1% common salt) and wheat straw in 65:35 ratio and supplemented with selenium (Se) as sodium selenite at 0 (T1, control), 0.15 (T2), and 0.30 ppm (T3) levels. Experimental feeding was done for a period of 90 days including a 6-day metabolism trial. To assess the growth performance, lambs were weighed every 15 days throughout the experimental period. All the lambs were intramuscularly inoculated with a single dose (2 ml) of haemorrhagic septicaemia oil adjuvant vaccine on 0 day to evaluate the humoral immune response. Blood samples were collected on 0 day and thereafter at 30 days interval. Results revealed that supplementation of Se both at 0.15 and 0.30 ppm levels had no significant (P > 0.05) effect on intake and digestibility of dry matter, organic matter, crude protein (CP), ether extract, neutral detergent fiber, acid detergent fiber, and hemicellulose; balances of calcium and phosphorus; and level and intake of digestible CP and total digestible nutrients. Se supplementation also had no significant (P > 0.05) effect on the levels of serum total cholesterol, total protein, albumin, globulin, albumin/globulin ratio, tri-iodothyronine (T(3)), thyroxine (T(4)), and T(4)/T(3) ratio; and serum glutamate oxaloacetate transaminase and serum glutamate pyruvate transaminase enzyme activity in the lambs. However, there was a significant (P < 0.05) increase in the plasma Se levels, red blood cell glutathione peroxidase enzyme activity, and humoral immune response in both the Se-supplemented groups. Feed (TMR) required per kilogram gain was less by 11.1% and 16.5% in groups T2 and T3, respectively, as compared to control (T1) group. Average daily gain was highest (108.5 g) in group T3, followed by group T2 (98.2 g), and lowest (89.06 g) in the control group (T1). These results indicated that supplementation of 0.15 and 0.3 ppm Se in the diet (having 0.19 ppm Se) of lambs significantly improves their immune response and antioxidant status.

Glutathione peroxidase responses in mature horses following the withdrawal of an organic selenium supplement

The study comprised 25 mature horses and incorporated five dietary treatments; a negative control (C: 0.085 ppm of Se in the diet), 3 levels of organic Se supplementation (S2, S3 and S4; 0.2, 0.3 and 0.4 ppm of Se on DM respectively) and one positive control supplemented with Na selenite (N3: 0.3 ppm of Se on DM). Diets were offered for 112 days (supplementary period) after which horses were blood sampled to determine GSH-Px activity. Sampling was repeated at 28 day intervals for the following 112 days (post-supplementary period). Increased GSH-Px activity was observed with ascending concentrations of dietary Se following the supplementary period. GSH-Px activities are still notably higher at the end of the post-supplementary period in S2, S3, S4 and N3 when compared to C, although rates of decline were greatest in those treatments with the highest levels of selenium supplementation. Furthermore, GSH-Px activity was better maintained in those animals that had received organic Se following the withdrawal of Se supplements. Therefore, from a nutritional viewpoint, organic forms of Se are superior to selenite as GSH-Px activity is maintained during periods of Se inadequacy.

Effects of Dietary Iodine and Selenium on the Activities of Blood Lymphocytes in Laying Hens

The effect of dietary iodine and selenium supplementation, alone or in combination, on peripheral blood lymphocyte function was determined in laying hens. Eight-hundred-and-sixty-four New-Loman laying hens were randomly allotted into 12 dietary treatments with different inclusion levels of iodine (0, 0.1 and 0.2 mg/kg), selenium (0, 0.05, 0.1 and 0.2 mg/kg) or their combinations for 24 weeks. The lipopolysaccharide (LPS) stimulation index, concanavalin A (ConA) stimulation index, peroxide enzyme activity and phagocytosis to neutral red particles were tested. There were significant differences in LPS stimulation index, ConA stimulation index, peroxide enzyme activity and phagocytosis to neutral red particles in different iodine or selenium supplementation levels (p<0.05). The highest iodine and selenium supplementation both resulted in highest LPS-/ConA-stimulation indices (p<0.05). However, when iodine was lower than 0.2 mg/kg, the additional effect of different levels of selenium did not always result in significant differences in these indices. The results indicated that iodine and selenium may affect immunity in laying hens and, when the iodine level in the laying hen is lower than 0.2 mg/kg, a selenium allowance higher than 0.1 mg/kg may be necessary to improve immunity. (Asian-Aust. J. Anim. Sci. 2006. Vol 19, No. 5 : 713-719)

Effect of selenium on selenoprotein P expression in cultured liver cells

Selenoprotein P and glutathione peroxidase are selenoproteins that are synthesized by hepatocytes. The production of these selenoproteins by human and rat liver cell lines has been assessed at several levels of selenium supplementation and compared with one another. HepG2 and H4IIE cells were cultured in serum-free medium without selenium supplementation for 48 h; then sodium selenite was added to the medium to give final concentrations of 0, 1, 2.5, 5, or 10 ng selenium/ml medium. After 48 h, selenoprotein P concentration in the medium, cellular glutathione peroxidase activity, and the mRNA levels of the two selenoproteins were determined. Selenium deficiency caused a decrease in selenoprotein mRNA and protein levels. The extent of decrease depended on the cell line examined. In selenium-deprived HepG2 cells, selenoprotein P release decreased to 10% of the release by selenium-replete cells. Under the same conditions, cellular glutathione peroxidase activity decreased to 33%. H4IIE cells showed the opposite results with cellular glutathione peroxidase activity decreasing to 13% and selenoprotein P release decreasing to 40% of selenium-replete cells. The effect of dithiothreitol on secretion of selenoprotein P by H4IIE cells was examined. Selenoprotein P secretion was inhibited by dithiothreitol, suggesting that disulfide bond formation is necessary for secretion of the mature protein.

Effect of Dietary Selenium on Plasma Selenoprotein P, Selenoprotein P1 and Glutathione Peroxidase in the Rat

The purpose of this study was to determine the effect of dietary selenium on the abundance of selenium in plasma selenoprotein P, selenoprotein P1 and glutathione peroxidase. Weanling rats were provided water that contained 1.0, 0.1 or 0.01 ppm selenium and 75Se for 21 days. Gel filtration of denatured subunits was used to identify 75Se in the selenoproteins. Rats provided 1.0 ppm selenium accumulated 1.5 times more 75Se in liver cytosolic selenoprotein P1, but not in the two other seleno-proteins, than did rats provided 0.1 ppm selenium. Most of the liver and blood selenium in rats provided 1.0 ppm selenium was insoluble and in an unknown chemical form. The tissue accumulation of unrecoverable selenium was apparently a response to the high dietary level of selenium. The proportion of selenium in plasma selenoprotein P, a putative selenium-transport protein, reflected the long-term selenium status of rats and varied from approximately 11–58% depending on the level of selenium supplementation. Turnover of selenium from this protein was affected by the dietary selenium of the rats. The results indicate that selenium incorporation into plasma selenoprotein P and selenoprotein P1 is affected by diet in ways that may reflect their importance to the rat.

THE EFFECT OF ADDED DIETARY SELENIUM ON THE SELENIUM CONTENT OF MILK, URINE AND FECES

Three sets of identical twin cows were used to quantitate the excretion of selenium in feces, urine and milk in response to increments of dietary selenium. The first trial consisted of three test periods, each 8 days long, separated by recovery periods of 5 days. A solution of sodium selenite was applied to the grain portion of the ration to provide 0, 6.0, 12.0, 24.0 and 48.0 or 100.0 mg of sodium selenite per day. Samples of milk, urine and feces were collected on the last 2 days of each treatment period and analyzed for selenium. There was a significant, positive linear (P &lt; 0.05) response between excretion of selenium in feces and increments of dietary selenium. There was a marked but variable response in selenium content of urine to dietary intake but selenium levels in milk were not increased above those of control animals. In a second trial, sodium selenite was fed at the rate of 170 and 260 mg per day for 10 days. These theoretically toxic levels resulted in 10- and 40-fold increases in the selenium levels of feces and urine, respectively, but only a 3-fold increase in selenium content of milk. At these high levels of selenium supplementation the amounts of selenium in the kidney and liver were increased above the normal values. This study shows that selenium in the form of sodium selenite would have to be fed at levels toxic to the cow before there would be any measurable increase of selenium in milk.

Dehydration and camel blood. I. Red blood cell survival in the one-humped camel Camelus dromedarius.

ARTICLESDehydration and camel blood. I. Red blood cell survival in the one-humped camel Camelus dromedariusR Yagil, UA Sod-Moriah, and N MeyersteinR Yagil, UA Sod-Moriah, and N MeyersteinPublished Online:01 Feb 1974https://doi.org/10.1152/ajplegacy.1974.226.2.298MoreSectionsPDF (522 KB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformation Cited Byدراسة مقارنة لكرات الدم الحمراء وخصائصها بين النوق وحيرانها الذكور في ليبيا31 December 2022 | Al-Mukhtar Journal of Sciences, Vol. 37, No. 4Water Resources, State of Play, and Development Prospects in the Steppe Region of Naâma (Western Algeria)20 July 2020Haematological reference values of dromedary camels in northern Nigeria20 July 2019 | Comparative Clinical Pathology, Vol. 28, No. 6Rates of erythropoiesis in mammals and their relationship with lifespan and hematopoietic stem cells aging4 March 2019 | Biogerontology, Vol. 20, No. 4Quality and quantity of dromedary camel DNA sampled from whole-blood, saliva, and tail-hair31 January 2019 | PLOS ONE, Vol. 14, No. 1Hematology28 August 2018High rate of adaptation of mammalian proteins that interact with Plasmodium and related parasites28 September 2017 | PLOS Genetics, Vol. 13, No. 9Genomics, phylogeny and in silico analysis of mitochondrial glutathione S-transferase-kappa from the camel Camelus dromedariusResearch in Veterinary Science, Vol. 97, No. 1Selenium in Camel – A Review8 July 2009 | Nutrients, Vol. 1, No. 1Effect of Different Selenium Supplementation Levels on Selenium Status in Camel12 February 2008 | Biological Trace Element Research, Vol. 123, No. 1-3Seasonal Variation in Blood Constituents of One-humped Camel (Camelus dromedarius)Pakistan Journal of Biological Sciences, Vol. 10, No. 8Mixed results of seven methods for organic residue analysis applied to one vessel with the residue of a known foodstuffJournal of Archaeological Science, Vol. 34, No. 1Mechanisms of Thermoregulation and Water Balance in Desert UngulatesWildlife Society Bulletin, Vol. 34, No. 3Comparative NMR studies of diffusional water permeability of red blood cells from different species. 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Camel (Camelus dromedarius) and alpaca (Lama pacos)Comparative Haematology International, Vol. 9, No. 1Effect of water deprivation on the disposition kinetics of enrofloxacin in camelsJournal of Veterinary Pharmacology and Therapeutics, Vol. 18, No. 5Determination of l-carnitine, acylcarnitine and total carnitine levels in plasma and tissues of camel (Camelus dromedarius)Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, Vol. 111, No. 3Antipyrine disposition in the dehydrated camelJournal of Veterinary Pharmacology and Therapeutics, Vol. 18, No. 2Selective brain cooling in desert animals: The camel (Camelus dromedarius)Comparative Biochemistry and Physiology Part A: Physiology, Vol. 101, No. 2Influence of dehydration and watering on camel red cell size: a scanning electron microscopic studyRespiration Physiology, Vol. 81, No. 3A comparative study of glycosylated haemoglobin level in the arabian camel (Camelus dromedarius) during different seasonsComparative Biochemistry and Physiology Part B: Comparative Biochemistry, Vol. 96, No. 4Liver function and protein binding in camelsComparative Biochemistry and Physiology Part A: Physiology, Vol. 93, No. 2Glycosylated haemoglobin: An indicator of long-term blood glucose in domestic sheep and goatsComparative Biochemistry and Physiology Part A: Physiology, Vol. 90, No. 2Halide concentrations in camel plasma in various states of hydrationBiological Trace Element Research, Vol. 12, No. 1Levels of glycosylated haemoglobin in the Arabian camel (Camelus dromedarius)Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, Vol. 86, No. 2Purine salvage as metabolite and energy saving mechanism in Camelus dromedarius: The recovery of guanineComparative Biochemistry and Physiology Part B: Comparative Biochemistry, Vol. 87, No. 1Evidence for two oxygen-linked binding sites for polyanions in dromedary hemoglobinEuropean Journal of Biochemistry, Vol. 150, No. 2Electrophoretic and quantitative studies of red cell glucose-6-phosphate dehydrogenase in the one-humped camel (Camelus dromedarius) in the sudanComparative Biochemistry and Physiology Part B: Comparative Biochemistry, Vol. 75, No. 2Osmotic fragility of desert bighorn sheep red blood cellsComparative Biochemistry and Physiology Part A: Physiology, Vol. 64, No. 1Permeability of erythrocytes to glycerol and its acylated derivatives in the camel and dogComparative Biochemistry and Physiology Part A: Physiology, Vol. 61, No. 2 More from this issue > Volume 226Issue 2February 1974Pages 298-300 Copyright & PermissionsCopyright © 1974 by American Physiological Societyhttps://doi.org/10.1152/ajplegacy.1974.226.2.298PubMed4811183History Published online 1 February 1974 Published in print 1 February 1974 Metrics