Selection For Daily Food Intake Research Articles

Associations of acute phase protein levels with growth performance and with selection for growth performance in Large White pigs

AbstractAbstract Acute phase proteins (APP) are released into the circulation in mammals upon infection and may be used to diagnose the health status of managed populations of animals such as pigs. The current study determines APP levels in a population of apparently healthy Large White pigs from a single farm, to address two questions: (1) whether phenotypic associations can be observed between productivity and APP, indicating the effects of possible subclinical infections and (2) whether previous selection for either food intake or ‘lean growth under restricted feeding’ influences APP levels. The APP investigated were alpha1- acid glycoprotein (AGP) and haptoglobin. The APP were measured at 18 and 24 weeks of age in pigs previously selected for high lean growth (no. = 31), low lean growth (no. = 38), high daily food intake (no. = 24) and low daily food intake (no. = 26), but performing under ad libitum feeding conditions. Performance traits and APP levels were constant over the experimental period, indicating that the farm health status did not vary over time. Performance traits and APP were recorded on 119 pigs, of which 80 had both APP and performance measurements. Multiple regression analyses were used to investigate phenotypic relationships between performance traits and APP levels. Plasma concentrations of AGP were higher in 18-week-old pigs compared with 24-week-old pigs (P< 0·01) whereas haptoglobin levels did not vary according to age. Significant sex differences in APP levels were observed. Females had higher circulating levels of AGP than males at both 18 weeks and 24 weeks. Females also had higher levels of haptoglobin at 18 weeks. Levels of AGP had significant negative correlations with daily weight gain (−0·59,P< 0·01 and −0·48,P< 0·05 at 18 and 24 weeks respectively) and with daily food intake (−0·53,P< 0·01 and −0·38,P< 0·05 at 18 and 24 weeks respectively). At age 24 weeks, haptoglobin was negatively correlated with both daily weight gain (−0·35,P< 0·05) and food efficiency (−0·34,P< 0·05). Pigs selected for high lean growth under restricted feeding had higher AGP levels than pigs selected for low lean growth under restricted feeding at 18 (593v. 332 μg/ml,P< 0·01) and 24 weeks of age (313 v. 219 μg/ml,P< 0·05). Selection for daily food intake did not consistently affect AGP levels, and neither selection criteria influenced plasma haptoglobin concentrations. To conclude, we have demonstrated that amongst contemporaneous pigs of the same genotype, higher systemic AGP levels and, to a lesser extent, higher haptoglobin levels are associated with decreased performance, and that genetic selection for ‘efficient lean growth under restricted feeding’ can increase serum AGP levels.

Physiological responses to divergent selection for daily food intake or lean growth rate in pigs

AbstractCorrelated responses in physiological traits to divergent selection on components of efficient lean growth identified physiological traits for use as predictors of genetic merit and provided a biological explanation for the between-selection line differences in protein and lipid deposition. Responses (differences between high (H) and low (L) selection lines) in protein metabolism during ad-libitum feeding were associated with divergent selection for daily food intake (DFI) (reduced serum creatinine concentration (H = 1·30 v. L = 1·56, s.e.d. 0·08 mg/dl)) and for lean growth rate on an ad-libitum feeding regime (LGA) (increased serum urea (H = 48 v. L = 36, s.e.d. 4 mg/dl) and creatinine (H = 1·74 v. L = 1·45 mg/dl)) concentrations, but not with selection for lean growth on a restricted feeding regime (LGS). Following 24-h fasting, responses in lipid metabolism, in the form of higher serum non-esterified fatty acid concentrations, were detected with divergent selection for both LGA (399 v. 248, s.e.d. 66 µmol/l) and LGS (H = 361 v. L = 107 µmol/l). The high LGS line appeared to ‘preserve’ protein to a greater extent than the high LGA line and similarly there was greater maintenance of lipid depots by the low LGS line compared with the low LGA line. A tentative ranking of the two pairs of lean growth selection lines on the basis of ‘importance’ of protein deposition would be high LGS, high LGA, low LGA and low LGS.Coheritabilities for serum creatinine concentration with predicted lysine balance and lysine required for protein deposition (-0·17 and 0·17, s.e. 0·08) indicated that serum creatinine concentration may usefully be included in breeding value prediction for lysine requirement and protein deposition to increase the accuracy of predicted genetic merit.Fasting did not increase the coheritabilities for serum creatinine concentration, so inclusion of serum creatinine concentration in a selection criterion for dietary lysine requirement or protein deposition does not require withdrawal of food before blood sampling animals.

Responses in gilt post-farrowing traits and pre-weaning piglet growth to divergent selection for components of efficient lean growth rate

AbstractResponses in gilt live weight, backfat depth and food intake during lactation and in pre-weaning piglet growth rate were examined after seven generations of divergent selection for daily food intake (DFI), lean food conversion (LFC) or lean growth rate (LGA) on ad-libitum feeding or lean growth on restricted feeding (LGS). There were 252 Large White gilts in the study. Selection for low DFI resulted in gilts with less backfat (25·7 v. 30·7 (s.e.d. 2·21) mm) at farrowing and a substantially lowerfood intake (129 v. 146 (s.e.d. 5) kg) during lactation, but similar reductions in live weight (42 (s.e.d. 6) kg) and backfat depth (8·4 (s.e.d. 1·7) mm) than with selection for high DFI. Therefore, the lower piglet growth (167 v. 295 (s.e.d. 11) g/day) with selection for low DFI compared with selection for high DFI was primarily due to lower food intake of the gilts, as energy for milk production from food was reduced. In contrast, selection for high LFC resulted in relatively smaller changes in live weight (37 v. 48 (s.e.d. 5) kg) and backfat depth (7·6 v. 8·9 (s.e.d. 1·3) mm) than selection for low LFC, which combined with a lower food intake (132 v. 148 (s.e.d. 4) kg) during lactation, resulted in lower piglet growth (181 v. 200 (s.e.d. 11) g/day). The higher food intake of high LGA gilts (137 v. 121 (s.e.d. 4) kg) compensated for the relatively lower reductions in live weight (41 v. 46 (s.e.d. 5) kg) and backfat depth (5·5 v. 6·7 (s.e.d. 1·3) mm) during lactation compared with the low LGA line, such that piglet growth was similar (195 v. 289 (s.e.d. 11) g/day) in the two selection lines. In the high and low LGS selection lines, piglet growth was similar (195 v. 186 (s.e.d. 11) g/day) as was gilt food intake (125 v. 227 (s.e.d. 5) kg) and the changes in live weight (39 v. 41 (s.e.d. 6) kg) and backfat depth (8·1 v. 7·7 (s.e.d. 2·2) mm) during lactation. An examination of the daily energy used in litter gain and the energy available from gilt food intake and mobilization of body lipid indicated that one equation to predict the amount of body lipid mobilized during lactation was not appropriate for different genotypes. Responses in gilt food intake and the changes in live weight and backfat during lactation were selection strategy dependent. However, in general, the selection strategies which reduced gilt voluntary food intake during lactation or resulted in lower live weight and backfat depth at farrowing were detrimental to piglet growth rate.

Responses in gilt traits measured during performance test, at mating and at farrowing with selection for components of efficient lean growth rate

AbstractThe responses in traits measured at the start of the mating period and at farrowing were examined after seven generations of divergent selection for daily food intake (DFI), lean food conversion (LFC), lean growth rate (LGA) on ad-\ibitum feeding and lean growth on scale feeding (LGS). Weight and backfat depth at mating were measured on 330 gilts and 74 boars, which were selected on the basis of performance test traits. Farrowing information was available on 259 gilts. At the start of the mating period, gilts selected for high DFI, LGA or LGS had similar live weights (135, 137 and 137 (s.e.d. 4·5) kg) but different backfat depths (20·3, 14·0 and 11·3 (s.e.d. 1·3) mm) while the corresponding low lines had different live weights (129, 117 and 124 kg), but similar backfat depths (17·5, 17·8 and 17·8 mm). Gilts selected for high LFC had lower mean live weight and backfat depth (114 kg and 10·7 mm) than gilts in the other selection lines. Conception rates of gilts selected for low DFI or high LGS were similar (0·62 and 0·64, s.e.d. 0·12) and lower than for the alternative selection strategies (0-78), but the low DFI gilts were significantly older at farrowing than gilts selected for high LGS (424 v. 408 (s.e.d. 5·5) days). Responses in live weight, backfat depth, age at mating and particular reproduction traits were selection strategy dependent, such that identification of relationships between growth and reproduction traits will require measurement of additional growth traits at an earlier age than in the current study

Reproductive performance of pigs selected for components of efficient lean growth

AbstractCorrelated responses in reproductive performance to five generations of divergent selection for daily food intake (DFI), lean food conversion (LFC), lean growth rate on ad–libitum feeding (LGA), and lean growth rate on scale feeding (LGS) were studied. Litter traits were measured on 1220 Large White gilts. Mean litter weights at birth and weaning were 12·9 kg and 63·5 kg, with average litter sizes of 10·3 and 7·9. Responses to selection in the high and low lines for litter size in the DFI and LFC selection groups were 1·9 and –1·5 (s.e.d. VI) at birth and 0·9 and –1·8 (s.e.d. 1·2) at weaning. Responses in litter birth weights were respectively positive and negative for DFI and LFC (3·0 and –2·8 (s.e.d. 1·4) kg) and the response in LGS (3 kg) was greater than in LGA (–0·1 kg). Selection line differences in litter weaning weight followed a similar pattern to birth weight for DFI and LFC (17·5 and –17·3 (s.e.d. 10·1) kg). Responses in litter weights were a result of selection line differences in both litter sizes and piglet weights. The relationships between litter size, litter weights and piglet weights at birth and weaning were essentially linear. An extra piglet at birth and weaning corresponded to an increase of 1·0 (s.e. 0·02) kg and 6·9 (s.e. 0·1) kg in litter weights. Piglet birth and weaning weights were decreased by 0·03 (s.e. 0·003) kg and 0·19 (s.e. 0·02) kg. A uterine constraint on piglet growth was implied, but there was no evidence for a limit to uterine capacity. Heritabilities for litter size, weight and piglet weight at birth of 0·06, 0·11 (s.e. 0·04) and 0·16 (s.e. 0·02) respectively were similar to those at weaning. Common environmental effects on piglet weights at birth and weaning were substantially higher than the heritabilities (0·38 and 0·45, s.e. 0·01). The study indicated that selection for lean growth on either an ad–libitum or restricted feeding regime did not significantly affect reproductive performance, but the high lean food conversion ratio and low daily food intake selection lines had impaired reproductive performance.