Research background: With the rapid development of civil engineering, the traditional low rise building model can no longer meet the needs of urbanization, and high-rise building structure has become the future development direction. In recent years, earthquake disasters occur frequently in China, which has caused huge losses to high-rise buildings. Therefore, we must strengthen the relevant research of high-rise building structures, which can make the high-rise building structural columns meet the requirements of safety performance. Therefore, the health detection and seismic performance evaluation of high-rise buildings will be of great significance. Research method: Through static elastic-plastic evaluation, we can calculate the dissipated strain energy of the structural column, which will further obtain the damage index of the structural column and obtain relevant data. Through this calculation method, we can complete the seismic performance evaluation of high-rise buildings, which is a calculation mode different from the traditional finite element software analysis. Through static elastic-plastic analysis, the seismic performance evaluation of high-rise buildings will have higher accuracy, which will build a damage index. Therefore, this paper uses a variety of research methods, mainly literature survey and empirical analysis. Through literature analysis, this paper can fully and correctly understand the methods of health detection and seismic performance evaluation of high-rise building structures at home and abroad, which will further clarify the current research level at home and abroad. Through empirical research, this paper analyzes specific examples, which can obtain more accurate results. Conclusion: In this paper, the seismic performance of high-rise buildings is comprehensively evaluated according to the damage index value of building structural columns. The simulation results show that more ideal seismic evaluation results can be obtained.