The Pliocene sands in the offshore parts of the Nile Delta Basin represent significant gas reservoirs. Several targets have been recently discovered in different places along the offshore Nile Delta Basin. The present work focuses on the possibility of discovering new natural gas resources at North Sinai Concession through an integrated method between seismic and well logs data interpretations. A case study from Kamose-1 Well at Kamose Field, North Sinai Concession has been examined. The quantitative explanation for the well log data of Kamose-1 Well has revealed two zones expected to be gas-bearing zones. These intervals are located between depths; 1174–1186 m (zone I) and between 1429 and 1503 m (zone II). The calculated petrophysical parameters for these zones exhibit low water saturation (24–43%), high effective porosity (30–31%), low shale volume (21–26%), high total porosity (37–38%) and low bulk volume of water (0.07–0.12). Zone II (74 m thick) shows a clear bright spot on the seismic profiles covering the study area, while, zone I is beyond seismic resolution (12 m thick). Several seismic bright spots have been outlined on the seismic data nearby Kamose-1 Well. The comparison between the newly outlined seismic bright spots with the drilled one in Kamose-1 Well exhibited a great similarity. Accordingly, these prospects are expected to be new targets for gas exploration in the Pliocene succession at North Sinai Concession.