Abstract Stream-terrace morphostratigraphy and optically stimulated luminescence (OSL) geochronology indicate that storm-driven sedimentation has caused down-system decoupling of the uppermost reaches of McMillan Creek (southern California, USA) from the lower reaches of McMillan Creek since 1960 ± 190 yr B.P. This is significant because source-to-sink studies report high degrees of sediment transport connectivity over millennial time scales during periods of high fluvial discharge in sediment routing systems. The most recent relatively large-magnitude episode of sedimentation emplaced a sediment slug in the ephemeral channel of McMillan Creek. The sediment slug is correlated to the “California Storm of January 1862” via OSL dating. In this paper, a conceptual model of sediment slug dynamics in an ephemeral stream over 16 decades is developed based on fluvial sedimentation events that in most instances included reworking slug-derived sediment. Due to the episodic nature of streamflow in ephemeral streams and the dearth of sediment transport between streamflow events, sediment slug coherency is sustained over longer periods of time in ephemeral streams than in perennial streams having steady or variable flow regimes. The longevity of sediment-slug coherency in ephemeral streams leads to more prolonged down-system decoupling in sediment routing systems than down-system decoupling caused by ordinary fluvial sedimentation. In McMillan Creek, it is possible that up-system decoupling driven by sedimentation has been contemporaneous with down-system decoupling, but factors other than sedimentation may have a more significant role in up-system decoupling. Source-to-sink studies completed in areas having a Mediterranean climate cannot assume that sediment flux out of upland source areas includes the total amount of sediment available for transport.