Currently, pharmacies are part of the healthcare system and must comply with the requirements for providing an accessible environment for people with disabilities, including providing them with the opportunity to receive the necessary pharmaceutical services. The aim of the study is to analyze the practical aspects of improving the professional competence of pharmacists in the field of interaction with people with limited mobility and disabilities in pharmacies. The texts of regulatory legal acts of the Russian Federation and also systemic and logical methods of their interpretation have been used in this study. It has been revealed that the current federal state educational standards of higher education and secondary vocational education in the specialty «Pharmacy» do not directly provide for the need to train future pharmacists in the basics of professional interaction with people with disabilities, but they establish the possibility of introducing additional competencies and/or new academic disciplines into the curricula for more in-depth training of graduates. It has been shown that pharmacists are required to have knowledge of the anatomical and functional characteristics of various groups of people with limited mobility and disabilities, their physiological states and pathological processes that directly affect their ability to receive pharmaceutical services in pharmacies. The possibility of pharmacists of pharmacies to consult people with limited mobility and disabilities on the necessary pharmacy goods online has been analyzed, taking into account possible functional disorders in these people – in various formats: text, audio only or using video communication. It has been proposed to introduce training on relevant aspects of their professional interaction with visitors to pharmacies with disabilities into educational programs for training and professional development of pharmacists.