The influence of environment in which students generally and specifically science students study on their academic performance is the main concern of this study. Biology, both as a subject and a discipline is a natural environment friendly endeavour. The environment of its study by students is very crucial. The objectives of the study included examining the influence of school location, security of school environment, home background of the students and cleanliness of the school on secondary school student’s performance in Biology. The sample size was six hundred and thirty-five (635) students (10% of the population) selected from five secondary schools out of the ten public schools. From the results, it was that concluded all the environmental factors considered in the study influenced the academic performance of Biology students in Owerri Municipal. It is recommended that all stakeholders in biology education of students should encourage and facilitate stronger partnerships between schools and home to ensure that everyone participates actively in and support students’ academic endeavors in biology through ensuring a healthy and secure school environment.
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