Blind tees, as important junctions, are widely used in offshore oil and gas transportation systems to improve mixing flow conditions and measurement accuracies in curved pipes. Despite the significance of blind tees, their unsteady flow characteristics and mixing mechanisms in turbulent flow regimes are not clearly established. Therefore, in this study, Unsteady Reynolds-Averaged Navier–Stokes (URANS) simulations, coupled with Explicit Algebraic Reynolds Stress Model (EARSM), are employed to explore the complex turbulent flow characteristics within blind-tee pipes. Firstly, the statistical flow features are investigated based on the time-averaged results, and the swirl dissipation analysis reveals an intense dissipative process occurring within blind tees, surpassing conventional elbows in swirling intensity. Then, the instantaneous flow characteristics are investigated through time and frequency domain analysis, uncovering the oscillatory patterns and elucidating the mechanisms behind unsteady secondary flow motions. In a 2D-length blind tee, a nondimensional dominant frequency of oscillation (Stbt = 0.0361) is identified, highlighting the significant correlation between dominant frequencies inside and downstream of the plugged section, which emphasizes the critical role of the plugged structure in these unsteady motions. Finally, a power spectra analysis is conducted to explore the influence of blind-tee structures, indicating that the blind-tee length of lbt = 2D enhances the flow-mixing conditions by amplifying the oscillation intensities of secondary flow motions.