Industry standard assessment of machined surface integrity typically requires a form of destructive testing to capture microstructural features such as white layers or distorted layers. The X-ray diffraction surface integrity inspection method (XRD-SIIM) offers a non-destructive alternative for the detection and sizing of fatigue-limiting microstructural features, without the sacrifice or alteration of a component which is required for cross-sectional microscopy. In this study XRD-SIIM was used to measure the surface integrity across a nickel-based superalloy gas turbine disc segment. XRD-SIIM microstructural feature detection and sizing models were trained and validated from a set of surfaces generated in a turning trial with a newly developed calibration procedure allowing these models to be adjusted for different instrument setups to facilitate measurement of the turbine disc segment. The non-destructive test was then able to show comparable inspection results to industry standard microscopy of microstructural features when inspecting the representative component, with over 90% of the outside surface of the component accessible by the diffractometer, and the internal surfaces accessible with appropriate hardware. Surface curvature only became a limiting factor for inspection of geometrical features with a small radius of curvature such as seal fins and the corner radii on fir tree sections.