The literature review on university cooperation in the Galicia-North Portugal Euroregion allows for the development of the script for in-depth interviews, a fundamental source of information in this study. The study explores student and academic mobility, as well as research mobility from Galicia to Northern Portugal, specifically towards the Escola Superior de Enfermagem Dr. José Timóteo Montalvão Machado for the former, and the Universidade do Minho for the latter. Emphasis is placed on understanding cross-border relations, the role of linguistic issues, how residence is addressed, and what the facilitators are. This exploratory research reveals the importance of relational capital in cooperation beyond the necessary community framework and the existence of formal structures, emphasizing the relevance of this Euroregion as a spatial frame of reference.