Anxiety Scores Research Articles

The Effectiveness of Cognitive Behavioral Therapy on Depression and Anxiety Symptoms in Breast Cancer Patients and Survivors: A Systematic Review of Interventional Studies.

Breast cancer (BC) is the most common type of cancer and the second cause of cancer-related death among women. Psychological treatments such as cognitive behavioral therapy (CBT) have been used as an effective method in the treatment of depression and anxiety in BC patients, and their effectiveness has been approved in various studies. The present study aimed to systematically investigate the effectiveness of CBT on depression and anxiety symptoms in BC patients and survivors. Electronic databases such as PubMed, Scopus, Web of Science [WOS], ScienceDirect, Cochrane Library, and Google Scholar were systematically searched from "October 2023" to "February 2024." The quality of the included studies was evaluated using the Critical Appraisal Skills Programme (CASP). In this study, the randomized controlled trials and quasi-experimental studies that assessed the effectiveness of CBT, cognitive behavioral group therapy (CBGT), and the combination of CBT with other psychological studies on depression and anxiety of BC patients and survivors were reviewed. Out of the 16 included studies, six used CBT, and six used CBGT. In the other four studies, a combination of CBT with other psychological interventions was implemented as an interventional program. Among 16 included studies, 14 studies showed that CBT, CBGT, and a combination of CBT with other psychological interventions significantly decreased the anxiety and depression scores among BC patients and survivors (p < 0.05), and only in two studies, no significant effect was observed. As most included studies showed the effectiveness of CBT in decreasing the depression and anxiety scores among BC patients and survivors, this study strongly suggests CBT as an effective non-pharmacological method for the treatment of psychiatric disorders of BC patients during cancer treatments and also for BC survivors.

The impact of whole-process visualization collaborative nursing discussions education on perioperative symptoms and emotional well-being in radical prostatectomy patients.

Prostate cancer is one of the most common malignant neoplasms in elderly males, with radical prostatectomy being the established therapeutic approach for localized disease. Patients undergoing this surgical procedure frequently experience increased negative emotions and symptomatology during the perioperative period, likely due to concerns about the illness and its treatment. The present study aims to investigate the effects of a novel educational approach involving a whole-process visualization and collaborative nursing discussions on perioperative symptoms and emotional well-being in radical prostatectomy patients. Data were prospectively collected from 310 patients admitted to the hospital between June 2021 and December 2023, all of whom were scheduled to undergo radical prostatectomy. These patients were randomly assigned to either the intervention group (receiving new model education) or the control group (receiving conventional education), with 155 patients in each group. The study compared basic demographic information, anxiety and depression scores, fear of disease progression scores, quality-of-life scores, main symptom scores, and changes in perioperative vital signs between the two groups. No statistically significant differences were observed between the two groups in terms of age, comorbidities, insurance type, education level, income, and tumor history (P > 0.05). Similarly, there were no significant differences in anxiety and depression scores, proportion of patients with anxiety and depression, vital signs, and fear of disease progression scores between the two groups at Time 1 stage (P > 0.05). During stages Time 2 and Time 3, the intervention group exhibited lower anxiety and depression scores, a lower proportion of anxious and depressed patients, as well as significantly reduced blood pressure and heart rate fluctuations compared to the control group (P < 0.05). Following radical prostatectomy, the main symptoms of patients, such as pain, nausea, and fatigue, were assessed using the MADIS Symptom Assessment Scale on days 1-3 post-surgery. The intervention group exhibited significantly lower scores for three symptoms compared to the control group (P < 0.05); at Time 4 stage, the patients in the intervention group also demonstrated significantly improved quality-of-life scores compared to the control group (P < 0.05). Additionally, blood pressure and heart rate of patients returned to baseline levels at Time 4 stage, with no significant difference between the two groups (P > 0.05). Nevertheless, the anxiety and depression scores in the intervention group at the Time 4 stage remained significantly lower than those in the control group (P < 0.05). Additionally, the fear of disease progression scores in both groups were lower than those at the Time 1 stage, with a more pronounced improvement observed in the intervention group compared to the control group (P < 0.05). Patients diagnosed with malignant tumors often experience fear and anxiety regarding the progression of their disease and upcoming surgery, as well as uncertainty surrounding their treatment and prognosis. This heightened emotional distress can contribute to a greater symptom burden during the perioperative period. Utilizing a whole-process visualization and collaborative nursing discussion approach, as compared to traditional communication methods, has been shown to alleviate patients' fears, reduce anxiety and depression, and ultimately lessen the symptom burden experienced during the perioperative phase. Ultimately, this approach can enhance the overall quality of life for patients facing malignant tumors.

Are the Effects of High-Intensity Interval Exercise on Executive Function, Mental Health, and Mood Obesity Dependent?

ABSTRACT Introduction High-intensity interval exercise (HIIE) is considered a time-efficient intervention to improve physical health in individuals with obesity. However, data on psychological outcomes are sparse. This study aimed to analyze and compare the acute effects of HIIE on executive function and mental health in young men with and without obesity. Methods Ten men with obesity (OB) (age, 23.10 ± 3.31 yr; body mass index (BMI), 34.6 ± 4.4 kg·m−2) and 10 with normal weight (NW) (age, 23.50 ± 1.64 yr; BMI, 23.1 ± 3.9 kg·m−2) underwent a single HIIE session. Outcomes were assessed at baseline, immediately after (AHS), 2 h after (AHS + 2), and 24 h after (AHS + 24) the HIIE session. Results Interaction effects showed that executive function was impaired in the OB group, with an average increase in reaction time of 407.80 ms (95% confidence interval (CI), 76.62–738.98 ms; P = 0.01) at AHS compared to baseline. Time effects were found for anxiety and depression scores at AHS + 2 for both groups compared to baseline (−2.75; 95% CI, −5.42 to −0.08; P = 0.04), and for anxiety scores at AHS (−2.55; 95% CI, −4.42 to −0.68; P = 0.004). Interaction effects were found for vigor scores at AHS + 2, with a decrease in vigor in the OB group and an increase in the NW group (P = 0.02). Conclusion Although anxiety and depression symptoms are improved 2 h after a HIIE session regardless of BMI category, individuals with obesity may present distinct results in executive function and vigor after a single HIIE bout.

Investigation of the mental health and cognitive correlates of psychological decentering in adolescence

ABSTRACT The ability to notice and reflect on distressing internal experiences from an objective perspective, often called psychological decentering, has been posited to be protective against mental health difficulties. However, little is known about how this skill relates to age across adolescence, its relationship with mental health, and how it may impact key domains such as affective executive control and social cognition. This study analysed a pre-existing dataset including mental health measures and cognitive tasks, administered to adolescents in Greater London and Cambridge (mean age (SD) = 14.4 (1.77) years, N = 553). A self-report index of decentering based on available questionnaire items in the dataset was developed. Multiple linear regression was used to examine associations between decentering and mental health, affective executive control (measured using an affective Stroop Task, affective Working Memory Task, and affective Sustained Attention to Response Task) and social cognition. Higher decentering was significantly associated with lower depression and anxiety scores and higher psychological wellbeing. Results did not indicate significant relationships between decentering, affective executive control and social cognition. Further research is needed to discover cognitive mechanisms associated with this process, which could allow for optimisation of existing psychological therapy and reveal new avenues of intervention.

ACUpuncture In The EmergencY Department (ACUITY): Results from a BraveNet Multi-Center Feasibility Randomized Controlled Trial

BackgroundPain plays a significant role in emergency department (ED) visits, however safe and effective nonpharmacologic options are needed. Prior studies of acupuncture in the ED reported pain reduction with minimal side effects, but most were small and single site. MethodsWe conducted ACUITY, a prospectively designed multi-center feasibility RCT. Our goal was to recruit 165 adults with acute non-emergent pain ≥4 on a 0-10-point scale at three EDs affiliated with BraveNet Practice Based Research Network. At baseline and 45-60 minutes later (post), participants self-assessed their pain and anxiety using a 0-10 rating scale. The primary feasibility outcome was recruitment of participants, whereas secondary outcomes were retention, and participant/provider acceptability. ResultsFrom May 3, 2021, to September 24, 2022, 632 eligible individuals were approached and 165 enrolled (165/632: 26.1%), meeting our recruitment goal. Notably, 42.4% of enrollees were Black/African American, 42.4% were White/Caucasian, and 13.9% were Hispanic/Latino. Participants were randomized to Acupuncture (n = 83) or Usual care (n = 82), of which 151 (91.5%) and 128 (77.6%) provided pain and anxiety scores at post-treatment and 1-week respectively. Acupuncture was rated acceptable to participants and providers. Mean pain ratings (pre-to-post) were 7.4 (2.2) to 4.8 (2.8) for acupuncture and 7.1 (2.3) to 6.4 (2.5) for usual care. Mean anxiety ratings (pre-to-post) were 4.5 (3.4) to 2.5 (2.6) for acupuncture and 4.1 (3.4) to 3.5 (3.2) for usual care. ConclusionSuccessful completion of ACUITY indicates we have the expertise and preliminary data to conduct a future definitive, multi-center RCT. Clinical Trials.govNCT04880733

Association of Food and Housing Insecurity on Outcomes in Pregnant Patients With Substance Use Disorder.

Food insecurity (FI) may be associated with worsened neonatal abstinence syndrome severity in infants born to individuals with substance use disorder. This study evaluates FI and housing insecurity (HI) influence on maternal and neonatal outcomes. This was a cohort study of patients receiving obstetric care through a multispecialty program in Kentucky from 2015 to 2023. Inclusion criteria were: (1) program participants over age 18 consenting to observational research, (2) delivering at University of Kentucky, and (3) not withdrawing from research at any time. Initially, a subset of patients for whom FI and HI concerns were heightened were screened. In 2019, FI and HI screening became standard of care at the clinic. Housing was assessed on enrollment. A validated 2-question Hunger Vital Sign FI screen was utilized for a subset of patients. Maternal and neonatal outcomes, including adverse delivery outcomes, maternal comorbidities, and birth complications, were observed. Fisher's exact and 2 sample t tests were performed. Of 494 participants, 188 (38%) identified at risk for HI. At enrollment, 221 (45%) individuals reported owning their primary residence, 85 (17%) were in group residential treatment, 34 (6.9%) had no housing, and 134 (27%) lived at another's residence. Disposition of a child to a relative or not the patient's own care was greater with HI, 51% versus 47%. Of 155 respondents, 96 (62%) reported FI, associated with increased neonatal intensive care unit (NICU) admission, 86% versus 74%. Using the validated tool, Abuse Assessment Screen, abuse was significantly greater with FI, 76% versus 58%. Edinburgh Postpartum Depression Scales >12 indicating depression were more common with FI, 63% versus 32%, P < .05. Anxiety scores were also higher with FI, P < .05. Patients with FI were more likely to experience abuse. FI and HI were health-related needs associated with increased anxiety, depression, infant NICU admission, and loss of child custody.

Basal cortisol level modulates stress-induced opioid-seeking behavior

In preclinical studies and our human laboratory, the α2-noradrenergic autoreceptor antagonist yohimbine was found to promote drug-seeking behavior. This study evaluated effects of dose-combinations of yohimbine and the glucocorticoid receptor agonist hydrocortisone to model intensity-dependent effects of stimulating each neurochemical system, alone and together, on stress-reactivity and opioid-seeking. Twelve regular heroin-using participants diagnosed with opioid use disorder (OUD) were stabilized on sublingual buprenorphine (8-mg/day), then passed a hydromorphone 18-mg vs. placebo intramuscular reinforcement screen. Across 9 experimental conditions (3 × 3 within-subject, randomized crossover, placebo-controlled, double-blind design) during inpatient buprenorphine maintenance, combinations of oral pretreatment doses of yohimbine (0, 27, 54-mg; t = 0 min) then hydrocortisone (0, 20, 40-mg; t = 45 min) were administered. In each condition, subjective drug and mood effects, cardiovascular responses, and saliva cortisol and α-amylase levels were assessed to evaluate stress-reactivity, and participants completed a 12-trial choice progressive ratio task during which they could earn units of hydromorphone (1.5-mg intramuscular) and/or money ($2.00). Yohimbine dose-dependently increased blood pressure, α-amylase, and anxiety scores, and decreased opioid agonist symptoms; hydrocortisone dose-dependently increased cortisol levels. Yohimbine/hydrocortisone dose-combinations significantly shifted within-session responding from money to opioid-seeking among participants with lower basal cortisol levels. These findings replicate yohimbine effects on stress biomarkers and demonstrate that noradrenergic/glucocorticoid-potentiated opioid-seeking is modulated by basal cortisol level. In persons with OUD stabilized on buprenorphine, basal HPA-axis activity and acute stressors can enhance opioid relative reinforcing efficacy. These factors may limit OUD treatment efficacy and highlight the need for novel interventions that prevent stress-induced opioid-seeking.

Investigating the psychological disorder and nutritional disorder during COVID-19 epidemic

BackgroundConsidering the various effects of the corona epidemic on humans, the current study was conducted to investigate adults' nutritional patterns and the psychological status during the COVID-19 pandemic. Methods and materialsThis cross-sectional analytical study was performed on adults in Iran during the COVID-19 epidemic. A total of 315 participants were examined by the convenience sampling method. To collect data from the standard 21 questionnaire (das) and Eating Attitudes Test - 26 items were used. The data were analysis by SPSS and independent t-test, correlation coefficient, and chi-square analysis of variance at a significance level of less than 0.05. ResultsThe mean age of the participants was 31.93±10.02 years. Based on the findings, 31.1% had some degree of depression, 29.5% had some degree of anxiety, and 31.7% have been affected by varying degrees of stress. Also, 8.7% of the participants had eating disorders. A statistically significant relationship was observed between depression score, anxiety score, stress score as well as an overall score of mental disorders and eating disorders; in such a way that with the increase of each of these cases, the score of eating disorders also increases. ConclusionFollowing the prevalence of the COVID-19 epidemic and its psychological effects, the level of stress and anxiety has increased. Awareness controlled the level of anxiety and stress and prevented its adverse effects on nutrition.

The effect of laughter yoga’s on perceived stress and anxiety levels in nursing students: Randomized controlled trial

BackgroundNursing education is a dynamic process that involves theoretical and applied teaching. The intense stress and anxiety experienced by students in this process negatively affect the learning processes and increase the likelihood of making mistakes. Non-pharmacological techniques have been widely used in recent years in the management of this stress. Laughter yoga is one of the new methods that are starting to be used to reduce stress and anxiety levels. PurposeThis study was conducted to determine the effect of laughter yoga on perceived stress and anxiety levels in nursing students. MethodsThe research is a randomized controlled trial with pre-test-post-test control group. This study was conducted in January-June 2022 at the Faculty of Nursing of a university in eastern Türkiye. The population of the study consisted of all students studying in the first year of the nursing faculty. The sample consisted of 103 students determined by simple random sampling method. Students were assigned to the experimental and control groups by simple randomization method. Students in the experimental group were given laughter yoga for 2 sessions per week (every 3 days, eight sessions in total), and the control group did not have any intervention. We used the “Perceived Stress Scale for Nursing Students” and “Condition Anxiety Scale”. Statistical analysis of the data of the research was performed using the IBM SPSS 22 package program. Statistical methods used to evaluate data: t-test in independent groups was used to compare the mean scores of the experimental and control groups, and paired sample t-test was used for intra-group comparisons. ResultsAfter the laughter yoga intervention, the post-test measurements of the intervention group and the control group showed a significant difference, and there was a significant decrease in perceived stress (p<0.001) and anxiety scores (p<0.001) before and after the laughter yoga intervention compared to the control group. ConclusionsLaughter yoga was found to be effective in reducing the levels of perceived stress and anxiety students perceived. Therefore, laughter yoga can be used as one of the effective strategies in reducing students' nursing education stresses.

The Impact of Shiatsu Massage on Labour Pain and Anxiety: A Randomized Controlled Trial.

Labour pain experienced by women during childbirth can significantly affect the mother's psychological condition and birthing process. This study aimed to determine the effect of shiatsu massage on pain and anxiety during labour. This randomized controlled trial was conducted on 80 nulliparous pregnant women who gave birth in four low-risk maternity clinics in Samarinda, Indonesia, from February to May 2022. The women were randomized into intervention (N=40) and control (N=40) groups based on random allocation. Certified midwives performed shiatsu massages following standard protocols. Pain was assessed using the Numeric Rating Scale, and anxiety was assessed using the Hamilton Anxiety Rating Score at three times including before the intervention (T0), the latent phase (T1), and at transition phase (T2). The impact of the intervention was analyzed using repeated measures analysis of variance by SPSS 26. A p-value less than 0.05 was considered statistically significant. The intervention group showed a significant reduction in labour pain scores from 6.85±1.00 (T0) to 6.13±0.88 (T1) and 4.78±0.83 (T2) (P<0.001), while the control group showed an increase from 6.85±1.00 (T0) to 8.05±0.64 (T1) and 8.85±0.48 (T2) (P<0.001). Anxiety scores in the intervention group decreased from 28.53±4.41 (T0) to 26.15±3.59 (T1) and 20.65±2.69 (T2) (P<0.001), whereas the control group experienced an increase from 25.55±3.16 (T0) to 27.05±3.36 (T1) and 31.73±3.27 (T2) (P<0.001). The between-subject effects in time levels for labour pain and anxiety in the two study groups had a significant impact (P<0.001). Findings showed that shiatsu massage was effective and safe for relieving pain and reducing anxiety during childbirth of nulliparous women. This research suggests that shiatsu massage can be used as an effective alternative method to relieve pain and anxiety during labour in low risk pregnancies, particularly in settings with limited access to pharmaceutical analgesics.Trial Registration Number: IRCT20220317054316N1.

The influence of AI Anxiety and Neuroticism in Attitudes toward Artificial Intelligence

This paper examines the impact of AI anxiety and neuroticism on attitudes toward Artificial Intelligence (AI) through a quantitative approach. With the pervasive integration of AI technologies across diverse domains like social media platforms, smart devices, healthcare, and education, gaining insight into how individuals perceive and engage with AI becomes essential. A sample of 197 participants (32 males, and 165 females) completed surveys assessing their levels of AI anxiety, neuroticism, and attitudes toward AI. The data were collected via Google Forms using the following structured questionnaires: Artificial Intelligence Anxiety Scale (AIA), Artificial Intelligence Attitude Scale (AIAS-4), and Neuroticism Scale. The findings indicate significant negative correlations between AI anxiety (r=-.286, p&lt;.01), neuroticism (r=-.196, p&lt;.01), and attitudes toward AI, suggesting that individuals with higher levels of AI anxiety and neuroticism are inclined towards adopting more skeptical viewpoints regarding AI technologies. Moreover, the AI anxiety subscales (learning, r=-.152, p&lt;.05; job replacement, r=-.257, p&lt;.01; sociotechnical blindness, r=-.302, p&lt;.01, and AI configuration, r=-.256, p&lt;.01) also showed negative significant correlations with the attitudes toward AI. At the same time, neuroticism showed significant positive correlations with the composite score of AI anxiety (r=.301, p&lt;.01) and all its subscales (learning, r=.219, p&lt;.01; job replacement, r=.250, p&lt;.01; sociotechnical blindness, r=.226, p&lt;.01, and AI configuration, r=.277, p&lt;.01). Understanding the role of AI anxiety and neuroticism in shaping attitudes toward AI can inform the development of strategies to mitigate negative perceptions and foster more positive attitudes toward AI technologies Keywords: artificial intelligence, anxiety, neuroticism, mediation

Theta Burst Stimulation Protocols for Schizophrenia

To date, several theta burst stimulation (TBS) protocols, such as intermittent TBS (iTBS), have been proposed; however, previous systematic reviews have revealed inconsistent efficacy findings in individual TBS studies for schizophrenia. To examine which TBS protocols are associated with the most favorable and acceptable outcomes in adults with schizophrenia. The Cochrane Library, PubMed, and Embase databases were searched for studies published before May 22, 2024. The inclusion criteria were as follows: (1) published and unpublished randomized clinical trials (RCTs) of any TBS treatment and (2) RCTs including individuals with schizophrenia spectrum disorders, other psychotic disorders, or both. This study followed the Cochrane standards for data extraction and data quality assessment and used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline for reporting. The risk of bias of individual studies was assessed using the second version of the Cochrane risk of bias tool, and the Confidence in Network Meta-Analysis application was used to rate the certainty of evidence for meta-analysis results. At least 2 authors double-checked the literature search, data transfer accuracy, and calculations. The primary outcome of this study was improvement in scores related to negative symptoms. Our frequentist network meta-analysis used a random-effects model. The standardized mean difference (SMD) or odds ratio for continuous or dichotomous variables, respectively, was calculated with 95% CIs. A total of 30 RCTs of 9 TBS protocols, with 1424 participants, were included. Only iTBS over the left dorsolateral prefrontal cortex (L-DLPFC) was associated with reduced negative symptom scores (SMD, -0.89; 95% CI, -1.24 to -0.55), overall symptom scores (SMD, -0.81; 95% CI, -1.15 to -0.48), Positive and Negative Syndrome Scale general subscale scores (SMD, -0.57; 95% CI, -0.89 to -0.25), depressive symptom scores (SMD, -0.70; 95% CI, -1.04 to -0.37), and anxiety symptom scores (SMD, -0.58; 95% CI, -0.92 to -0.24) and improved overall cognitive impairment scores (SMD, -0.52; 95% CI, -0.89 to -0.15) compared with a sham. However, positive symptom score changes, all-cause discontinuation rate, discontinuation rate due to adverse events, headache incidence, and dizziness incidence did not significantly differ between any TBS protocols and sham. In this network meta-analysis, iTBS over the L-DLPFC was associated with improved scores for negative, depressive, anxiety, and cognitive symptoms in individuals with schizophrenia and was well tolerated by the participants. Other forms of TBS were not associated with benefit. Further research is needed to assess the potential role of TBS in the treatment of schizophrenia.

A genome-wide gene-environmental interaction study identified novel loci for the relationship between ambient air pollution exposure and depression, anxiety

BackgroundGenetic factors and environmental exposures, including air pollution, contribute to the risk of depression and anxiety. While the association between air pollution and depression and anxiety has been established in the UK Biobank, there has been limited research exploring this relationship from a genetic perspective. MethodsBased on individual genotypic and phenotypic data from a cohort of 104,385 participants in the UK Biobank, a polygenic risk score for depression and anxiety was constructed to explore the joint effects of nitric oxide (NO), nitrogen dioxide (NO2), particulate matter (PM) with a diameter of ⩽2.5 μm (PM2.5) and 2.5–10 μm (PMcoarse) with depression and anxiety by linear and logistic regression models. Subsequently, a genome-wide gene-environmental interaction study (GWEIS) was performed using PLINK 2.0 to identify the genes interacting with air pollution for depression and anxiety. ResultsA substantial risk of depression and anxiety development was detected in participants exposed to the high air pollution concomitantly with high genetic risk. GWEIS identified 166, 23, 18, and 164 significant candidate loci interacting with NO, NO2, PM2.5, and PMcoarse for Patient Health Questionnaire-9 (PHQ-9) score, and detected 44, 10, 10, and 114 candidate loci associated with NO, NO2, PM2.5, and PMcoarse for General Anxiety Disorder (GAD-7) score, respectively. And some significant genes overlapped among four air pollutants, like TSN (rs184699498, PNO2 = 3.47 × 10−9; rs139212326, PPM2.5 = 1.51 × 10−8) and HSP90AB7P(rs150987455, PNO2 = 1.63 × 10−11; rs150987455, PPM2.5 = 7.64 × 10−11), which were common genes affecting PHQ-9 score for both NO2 and PM2.5. ConclusionOur study identified the joint effects of air pollution with genetic susceptibility on the risk of depression and anxiety, and provided several novel candidate genes for the interaction, contributing to an understanding of the genetic architecture of depression and anxiety.

The Impact of Mindfulness-Based Counseling on the Mental Health of Women With a History of COVID-19 During Pregnancy: A Quasi-Experimental Study.

With the spread of COVID-19, certain population groups, including pregnant women, were more susceptible than others. This disease can lead to postpartum complications, including mental disorders, in mothers. Few studies have investigated the impact of mindfulness-based interventions on mental health, and the most effective counseling approach to promote mental health has not been identified. This study aimed to determine the impact of online mindfulness-based counseling on improving mental health among women with a history of COVID-19 during pregnancy in Iran. The present study was a quasi-experimental design conducted on 100 women with a history of coronavirus infection during pregnancy referred to the Mother's Clinic of Yahya Nejad and Ayatollah Rouhani Educational-Treatment Hospital, affiliated with Babol University of Medical Sciences, Iran, via convenience sampling. The women were randomly assigned to the intervention (mindfulness-based counseling) and control groups. The intervention group received eight 45-min weekly mindfulness-based counseling sessions over 8 weeks. Data were collected via a demographic information questionnaire and the Goldberg General Health Questionnaire before and after the intervention, which were completed by both groups. Independent t-tests and analysis of covariances (ANCOVAs) were used to compare the outcomes of the two groups. After controlling for confounding variables, the mean mental health scores before and after counseling were 29.42±4.49 and 19.80±3.88, respectively, in the intervention group and 26.26±2.29 and 25.92±2.15, respectively, in the control group. The mean mental health score in the intervention group was significantly lower than that in the control group (F=266.7, p<0.001). The mean scores for somatic symptoms (F=89.30, p<0.001), depression symptoms (F=142.71, p<0.001), anxiety and insomnia symptoms (F=120.56, p<0.001), and social dysfunction scores (F=127.77, p<0.001) were significantly different between the two groups after counseling. The findings indicated that online mindfulness-based counseling positively affects mental health and its domains during the postpartum period. However, further randomized clinical trials are needed before a definitive conclusion can be drawn. We were not allowed to register according to the law of our country.

The relationship between patient-reported experience and patient-reported outcomes in patients with cancer.

248 Background: Measures of patient experience (PEX) and patient-reported outcomes (PRO) are used by health systems across the US to improve care delivery and quality of life, respectively. Despite their widespread use, little is known regarding the relationship between these two types of patient-generated data. From 2018 to 2023, we conducted a pragmatic type-II hybrid effectiveness/implementation study of an electronic health record (EHR)-embedded symptom management program (eSyM) across six diverse cancer centers. This project focused on patients who started chemotherapy (CHEMO) or had surgery (SURG) for a suspected or confirmed gastrointestinal, gynecologic, or thoracic malignancy. Methods: We conducted a cross-sectional study of adults who were eligible for either the control or intervention arm of the eSyM study to determine if patients who reported having an inferior care-team experience were more likely to report having worse symptoms. Participants completed a one-time survey via REDCap that included elements from the Consumer Assessment of Healthcare Providers and Systems (CAHPS) and the Patient-Reported Outcomes Measurement Information System (PROMIS). Analyses determined the extent to which PEX measures were associated with PRO measures by evaluating differences in mean PROMIS scores for those who rated their PEX highly vs. not highly. Results: In total, 1419 respondents reported having cancer for which they received care at a participating center: median age 66, 63% female, 5% black, 13% disabled, 66% married/partnered, 23% high school or less education, 22% somewhat-extreme difficulty paying bills. For both CHEMO and SURG patients, 82% rated their overall cancer care-team experience highly (top box score of 9-10). Compared to patients who did not rate their care-team experience highly, those who did reported better scores for depression, fatigue, anxiety, pain interference, physical function, and self-efficacy (Table). PROMIS values differed for other CAHPS measures too. Conclusions: Among patients receiving routine cancer care, there was a significant association between PEX and multiple PROs. Further investigation of the nature and strength of the association between PEX and PRO measures is warranted. If confirmed, this association could lead to the development of interventions that impact both patient satisfaction and quality of life. Clinical trial information: NCT03850912 . Mean difference in PROMIS scores for patients who rated their care-team experience highly versus not highly (P from two-sample T-test). CHEMO (N=889) SURG (N=530) Mean Diff 95%CI P value Mean Diff 95%CI P value Depression -2.7 -4.3, -1.1 0.001 -3.3 -5.3, -1.4 &lt;0.001 Anxiety -3.7 -5.4, -1.9 &lt;0.001 -3.6 -5.7, -1.5 &lt;0.001 Fatigue -2.3 -4.0, -0.5 0.011 -4.5 -6.8, -2.2 &lt;0.001 Pain interference -3.6 -5.3, -1.9 &lt;0.001 -4.7 -6.7, -2.7 &lt;0.001 Physical function 1.6 0.1, 3.1 0.042 3.5 1.4, 5.6 0.001 Self-efficacy 3.9 2.6, 5.2 &lt;0.001 6.4 4.6, 8.1 &lt;0.001

Exploring Long-Term Determinants and Attitudes Toward Smartphone-Based Commercial Health Care Applications Among Patients With Cancer.

Our study explores how attitudes of patients with cancer toward smartphone-based commercial health care apps affect their use and identifies the influencing factors. Of the 960 patients with cancer who participated in a randomized controlled trial for a smartphone-based commercial health care app, only 264 participants, who completed a survey on app usage experiences conducted between May and August 2022, were included in this study. Participants were categorized into three groups: Positive Persistence (PP), Negative Nonpersistence (NN), and Neutral (NE) on the basis of their attitude and willingness to use smartphone-based commercial health care apps. The Health-Related Quality of Life (QOL) Instrument (8 Items), European QOL (5 Dimensions; 5 Levels), The Human Interaction and Motivation questionnaire, and open-ended questionnaires were used to examine factors potentially influencing extended utilization of digital interventions. Despite demographic similarities among the three groups, only the PP and NE groups showed similar app usage compared with the NN group. The combined group (positive persistence and neutral) exhibited significant improvement in depression (P = .02), anxiety (P = .03), and visual analog scale scores (P = .02) compared with the NN group. In addition, patient interaction (P < .01) and the presence of a chatbot/information feature on the app (P < .01) demonstrated a significant difference across the three groups, with the most favorable response observed among the PP group. Patients were primarily motivated to use the app owing to its health management functions, while the personal challenges they encountered during app usage acted as deterrents. These findings suggest that maintaining a non-negative attitude toward smartphone-based commercial health care apps could lead to an improvement in psychological distress. In addition, the social aspect of apps could contribute to extending patient's utilization of digital interventions.

Psychological Profile of Patients Presenting with Dermatological Complaints: A Cross-sectional Study

Objectives: The study evaluates the psychological profile in patients presenting to a dermatological clinic in Mumbai, India. Materials and Methods: We evaluated anxiety, depression, stress, anger, body image, and relationships in 63 outpatients presenting with dermatological complaints. We used linear regression models for multivariate analyses for coefficient and 95% confidence intervals (CIs). Results: The mean age (standard deviation [SD]) was 37.4 (14.9) years; 30 (51%) were female and 31 (49%) were male. The common diagnoses were papulosquamous conditions (24%), acne (18%), hair fall (15%), pigmentary conditions (11%), pruritus (10%), and infection (8%). The mean anxiety (SD) score was highest in pigmentary conditions (11.6 [13.9]), depression (15.0 [5.0]) and posttraumatic stress scores (16.3 [25.6]) in pigmentary conditions, social phobia scores in allergy (21.8 [17.0]), and anger scores in acne (25.4 [6.3]). The mean (SD) family scores were lowest in pruritus (8.0 4.2]), body image in infection (3.6 [0.9]), and self-image in pigmentation (6.0 [2.3]). The mean social phobia scores were higher in allergy compared with acne (12.2, 95% CI: 1.6, 22.8, P = 0.02). Body image scores were lower in pruritus (−7.7, 95% CI: −14.5, −0.9, P = 0.03). Conclusion: The psychological parameters differ in various dermatological conditions; hence, a complete profile analysis will be beneficial for designing interventions in these patients.

Coping style and psychopathological morbidity in patients with advanced melanoma: differences between cancer therapy, metastatic location and staging.

The incidence of melanoma has been steadily increasing in recent years and remains one of the most frequent cancers in adolescents and young adults. The literature shows how a high percentage of melanoma patients present with high anxiety and depression scores and a correlation between worsening quality of life and impaired body image has been shown. The present study aimed to investigate the relationship between cutaneous and visceral metastasis in a group of 73 patients with advanced melanoma in relation to body image, anxiety, depression, and coping style. Hospital Anxiety and Depression Scale, Body Image Scale and Mini-Mac questionnaires were administered to a sample of 73 subjects with advanced melanoma (stage III and IV); Analyses were performed with SPSS version 28.01 and a P value <0.05 was considered significant. Emerging results indicated greater body image impairment in patients with skin metastasis, no significant difference in anxiety and depression by staging. Patients receiving target therapy showed a reduction in anxiety and depression compared with patients receiving immunotherapy. In line with the literature, cutaneous metastatic involvement negatively affected body image, a prevalence rate of anxiety and depression of 28,8% and 19.2%, respectively, emerged in the sample, while 17.8% reported significant body image impairment, suggesting how melanoma impacts in patient's quality of life.

Anime watching: is a new kind of addiction? Evaluation of psychopathologies and psychosocial factors associated with problematic anime watching among adolescents

BackgroundIn recent years, with the rapid development of technology, research on behavioral addiction concepts such as digital gaming disorders and problematic internet use has increased. As anime-watching has become widespread worldwide, it is thought that this behavior may be one of the areas of problematic technology use, especially in adolescence. However, studies evaluating problematic anime-watching behaviors within the framework of behavioral addictions are quite limited in the literature. In this study, problematic anime-watching behaviors, comorbid psychiatric disorders, and possible psychosocial factors were evaluated in 86 anime watchers aged between 12 and 18 years. Problematic anime-watching behaviors were evaluated according to the diagnostic criteria of other defined disorders related to addictive behaviors in ICD-11. A semi-structured interview tool was used to assess psychiatric comorbidities, and the IGDS9-SF adapted form for anime-watching, the Self-Efficacy Scale for Children, KIDCOPE, and the Social Anxiety Scale for Adolescents were used to collect other data.ResultsIt was determined that 36.8% of the 86 adolescents in our study had problematic anime-watching behavior. Compared to other adolescents, the problematic anime-watching group had significantly lower self-efficacy scores and significantly higher social anxiety and avoidant coping scores. A significant relationship was found between social anxiety disorder and watching problematic anime.ConclusionsThe present study showed that problematic watching of anime may be a variant of behavioral addiction. In conclusion, the relationship between problematic anime-watching behaviors and mental health warrants further examination.

A two-institution pilot study on the psychological burden and distress of parents caring for children with shunted hydrocephalus.

Little is known about the emotional health of parents caring for children with shunted hydrocephalus. The aim of this pilot study was to find out whether parents caring for shunt-treated hydrocephalic children experience serious psychological problems and psychosocial distress and whether these problems are related to the sociodemographic background of the caregivers, the clinical characteristics of their children, and parents' illness-related concerns and perceived burden of their children's illness. This pilot study was performed in an outpatient setting at two German hospitals. The following questionnaires were handed out to parents of children with shunted hydrocephalus (< 21 years of age): the Patient Health Questionnaire (PHQ-9) for depression, the Generalized Anxiety Disorder Scale (GAD-7) for anxiety, the Distress Thermometer (DT) for psychosocial distress, the Hydrocephalus Concerns Questionnaire (HCQ) for assessment of parents' illness-related concerns, and the Hydrocephalus Outcome Questionnaire (HOQ) for assessment of perceived children's disease burden. Clinical data of the respective children were collected from electronic charts. Parents' demographic data were evaluated via questionnaires. Parents' psychological variables were correlated with demographic and clinical data and HCQ and HOQ scores. Regression analyses of HCQ and HOQ scores with psychological items were performed. Sixty-three parents were included in this study. Of these, 60% reported clinically relevant levels of either depression (11%), anxiety (10%), and/or psychosocial distress (57%). There were no associations between parental sociodemographic or children's clinical characteristics with parents' psychosocial well-being or psychosocial distress. Depression, anxiety, and DT scores were highly intercorrelated and significantly correlated with HCQ scores (r = 0.508, r = 0.516, r = 0.442; p < 0.01). Thereby, worries about shunt-related complications were the most reported concern in the HCQ. Depression and anxiety correlated with the scores of some HOQ subcategories. In preliminary regression analyses, higher illness-related concerns predicted occurrence of parents' anxiety. The authors' results support the notion that there is a need for psychosocial support for a proportion of parents who care for shunted hydrocephalic children. Perceived child symptom burden and parental illness concerns were identified as relevant correlates of parental psychological well-being. Thus, concerns specific to shunt-related problems could be a first starting point for the development of individual support measures.