Scientific Union Research Articles

Cognitive Brain of Homo sapiens: Stress, Emotions, Health, Hormones, Longevity

Replication of new discoveries in the field of genetics and epigenetics, the scientific union of neurobiology and neurophysiology of the quantum brain HOMO SAPIENS of the 21st century, the achievements of biophysics, hybrid neuroimaging and nuclear medicine, the introduction of nutritionology and bioelementology technologies, the 5P of MEDICINE and 5G TECHNOLOGY, compliance of art medicine and modern psychoanalysis, - will allow control the cognitive brain of a 21st century HUMAN. Scientific progress and 33 years of experimental experience of biophysics in the field of neurogeriatrics and neurocardiology, neuroendocrinology and psychoneuroimmunology - made it possible to argue that "nerve cells are restored," the quantum human brain is CONTROLLED, high-quality and healthy LONGEVITY HOMO SAPIENS of the 21st century is achievable. Children who experience chronic stressors are vulnerable to lifelong emotional and physical health problems. Cognitive and mental health affects a person's ability to cope with stress, maintain a relationship paradigm, make healthy choices and lead a fulfilling life. An increase in the expected and average life expectancy of a person is realizable/achievable/feasible when creating conditions/tools/algorithms/technologies for active and high-quality longevity.

Science of Cognitive Brain and Quantum Biophysics Homo sapiens 21st Century: hybrid Neuroimaging and Nuclear medicine, 5P Medicine and 5G Technology, Neurobiology and Neurophysiology of Quantum Brains, Psychoanalysis, Art-Medicine, Bioelementology and Nutriciology

New discoveries in the field of genetics and epigenetics, the scientific union of neurobiology and neurophysiology of the quantum brain Homo sapiens of the 21st century, the achievements of biophysics, hybrid neuroimaging and nuclear medicine, the introduction of nutritionology and bioelementology technologies, the 5P of Medicine and 5G Technology, the replication of compliance of art medicine and modern psychoanalysis made it possible to manage 21st century Human cognitive brain. Scientific progress and 33 years of experimental experience of biophysics in the field of neurogeriatrics and neurocardiology, neuroendocrinology and psychoneuroimmunology made it possible to argue that “nerve cells are restored”, the quantum human brain is Controlled, high-quality and healthy longevity Homo sapiens of the 21st century is achievable. Humankind needs to know (discover, prove) in the near future the existence of more than 450 trillion neurosynaptic and neurocosmic interactions between the cognitive mind and the universe.

An Optimal Opportunistic Maintenance Planning Integrating Discrete- and Continuous-State Information

Information-driven group maintenance is crucial to enhance the operational availability and profitability of diverse industrial systems. Existing group maintenance models have primarily concentrated on a single health criterion upon maintenance implementation, where the fusion of multiple health criteria is rarely reported. However, this is not aligned with actual maintenance planning of multi-component systems on many occasions, where multi-source health information can be integrated to support robust decision making. Additionally, how to improve maintenance effectiveness through a scientific union of both scheduled and unscheduled maintenance remains a challenge in group maintenance. This study addresses these research gaps by devising an innovative multiple-information-driven group replacement policy for serial systems. In contrast to existing studies, both discrete-state information (hidden defect) and continuous degradation information are employed for group maintenance planning, and scheduled postponed maintenance and unscheduled opportunistic maintenance are dynamically integrated for the first time to mitigate downtime loss. To be specific, inspections are equally spaced to reveal system health states, followed by the multi-level replacement implemented when either (a) the degradation of the continuously degrading unit reaches a specified threshold, or (b) the age of the multi-state unit since the defect’s identification reaches a pre-set age (delayed replacement). Such scheduling further enables the implementation of multi-source opportunistic replacement to alleviate downtime. The Semi-Markov Decision Process (SMDP) is utilized for the collaborative optimization of continuous- and discrete-state thresholds, so as to minimize the operational costs. Numerical experiments conducted on the critical structure of circulating pumps verify the model’s applicability.

Computational Analysis of Nanocarriers in the Tumor Microenvironment for the Treatment of Colorectal Cancer

Colorectal cancer is currently treated by surgical procedures, chemotherapy and radiotherapy; however, these latest treatments are highly aggressive, with side effects that affect the patient’s quality of life. The scientific union has been investigating other more favorable alternatives, such as targeted therapy, which seeks greater selectivity in the type of target cells. This type of treatment can significantly reduce side effects in the patient. The goal of this research is to computationally visualize the behavior of nanocarriers in the colon tumor microenvironment, as well as their capacity for deepening, selective coupling and differentiating between healthy and cancerous tissue. A group of histological samples of cancerous tissue was selected, based on morphological criteria and the stage of the disease. This was used to elaborate 2D and 3D models to study different cases using artificial vision and computer simulation techniques. The results indicated velocities of the nanocarriers that reached values between 1.40 and 8.69×10−7ms for a time of 3.88 h, with a vectorized deposition efficiency of 1.0 to 4.46%. In addition, selective mating events were achieved at a maximum depth of 4.68 × 10−4 m. This scientific knowledge can contribute to the estimation of the efficacy of the treatment, as well as the assessment for different dosage levels and frequency of drug administration from the studies carried out on the lesion.

«Реабилитация. Искусство. Педагогика». III Международная онлайн-школа по физиологии выразительного движения

The article is devoted to a review of the 3rd international online school on the physiology of expressive movement “Rehabilitation. Art. Pedagogy”, which took place on November 16th, 2022. The main topic of the scientific discussion was the phenomenon of expressive movement as a manifestation of the creative and motor abilities of a person, as well as it being one of the possible markers of his inner, spiritual world. Two previous online schools have shown that this topic seems to be very interesting to a wide range of scientific community, which includes representatives of the medical rehabilitation sphere, the performing arts, dance history researchers, physiologists and body-oriented therapists. However, this time the concept of the school was aimed at finding points of contact between the direct experience of theatre pedagogy and practicing psychologists and physiologists. This concept has become not only a characteristic feature of the 3rd online school, but also revealed a special scientific approach, which is the interdisciplinary nature of the discussion. The event was organized by the Russian Medical Academy of Continuing Professional Education of the Ministry of Health of the Russian Federation together with the Russian Institute of Theatre Arts (GITIS) (as a part of the “Priority-2030” Strategic Academic Leadership Program) under the support of the National Association of Physiotherapy and Balneology. Such a scientific union is significant for further research. Since the school is an interdisciplinary one, which makes it unique, the article presents brief summaries of the reports that present a wide range of scientific and practical issues of physiotherapy, rehabilitation, theatre pedagogy, and the history of plastic expressiveness.

Women in physics

Abstract The International Union of Pure and Applied Physics (IUPAP) is the scientific union representing identified physics communities from all over the world. It currently has 60 country members and is organized and run by the physics community itself. About to turn one hundred years old, the IUPAP has taken several actions for over 20 years to increase the participation and improve the situation of women physicists. The creation of its Working Group on Women in Physics in 1999 has had an enormous impact on the physics communities giving visibility to a problem that had often gone unnoticed, raising awareness and, most importantly, creating a very active network of women physicists in more countries than IUPAP members. The Working Group has also had a direct impact on the IUPAP’s organization and on the activities it sponsors. In this paper I give a brief account of the actions of the Working Group and of the measures that the IUPAP has taken since 1999 to help reduce the gender gap in physics and in STEM. I then focus on the many activities that it led to in Latin America, the region of origin of three of the five chairs of the Working Group.

Búsqueda de información científica para la mejora de contenidos en protocolos de investigación en asignaturas de apoyo a la titulación en la ingeniería

La formación profesional de un Ingeniero debe ser integral y cumplir con competencias que aportan en la construcción de su conocimiento, la competencia de investigación es el eje medular de este trabajo y representa el área de mejora a atender; los alumnos presentan deficiencias en la búsqueda de información científica para la generación de protocolos de investigación. Esta investigación tiene como objetivo, mejorar las estrategias de búsqueda y gestión de la información para la elaboración de protocolos de investigación mediante recursos tecnológicos y motores de búsqueda para obtener productos finales de calidad científica. Se aplican dos encuestas, de diagnóstico y de mejora, ésta última se aplica en dos momentos: antes de brindar soporte de contenido en la búsqueda de información y después de haberlo hecho, demostrando que se mejora la calidad de los productos obtenidos en las asignaturas de la línea de investigación. Se aplica durante 3 semestres escolares (tiempo1, tiempo2 y tiempo 3) a un total de muestra acumulado de 230 alumnos. La investigación es cuantitativa con diseño no experimental longitudinal de tendencia con un alcance descriptivo. Los resultados diagnósticos indican que Google es el recurso más utilizado por los alumnos para realizar sus investigaciones. Los resultados muestran una mejora en la calidad de los contenidos en protocolos de investigación al brindarles materiales exclusivos de ésta temática durante el curso. Se concluye que los alumnos necesitan una guía docente o de contenido para hacer búsquedas efectivas de información en espacios formales y reconocidos para el gremio científico.

Внесок Ю. А. Кулаковського в розвиток античної археології в Історичному товаристві Нестора Літописця

In the history of Ukrainian archeology there are many names of outstanding researchers who have devoted their lives to the study of our antiquity. Among them – Yulian Kulakovskyi, a well-known domestic historian and archeologist. For many years of his life he devoted to the scientific and pedagogical activity at the Kyiv University of St. Vladimir, where he had worked at the Faculty of History and Philology. After moving to Kyiv, Yu. A. Kulakovskyi began interesting in the late Ancient Christian archeology of the Crimea. In 1883 Yu. A. Kulakovskyi had joined the Nestor Chronicler Historical Society. Since that time, his life and career have been closely linked to this scientific union. For many years he represented the Nestor Chronicler Society at the All-Russian Archaeological Congresses. In 1905, for his extraordinary merits, Yu. A. Kulakovskyi was admitted to the Honorary Members of the Society, and from 1907 to 1911 performed the duties of its President. Kulakovskyi's presidency was one of the most productive periods of the Society's activity, meetings and public lectures were held during which scientific reports were read. The fascination of Yu. A. Kulakovskyi with archeology began after his move to Kyiv. For many years he was an active participant in archaeological research in the outskirts of Kerch, near Mithridat mountain. The results of these studies have been dedicated to a series of reports published on the pages of “Readings in the Nestor Chronicler Historical Society”. It is possible to consider that he initiated the direction of research in the field of Late Antique archeology of the Crimea in the Society. For the first time in the history of Bosporan archeology, the researcher not only conducted excavations of the most valuable early Christian funeral sites, but he also explored much of the necropolis, discovered unique burial sites, some of them are known for their wall paintings. Thanks to the efforts of the scientist it was possible to solve important questions of the borders of the ancient necropolis, chronology and cultural identity of the ancient population of Crimea. The researches of Yu. A. Kulakovskyi made it possible to begin systematic excavations of the ancient Panticapeus, which allowed to preserve the unique archaeological materials, which later became the subject of careful study of modern scientists.

ПЕРЕДМОВА

ПЕРЕДМОВА

Иcторик С.К. Бушуев: «… Я могу считать себя кавказским пленником в течение 20 лет» (развитие исторической науки в Республике Адыгея).

Иcторик С.К. Бушуев: «… Я могу считать себя кавказским пленником в течение 20 лет» (развитие исторической науки в Республике Адыгея).

Amphiphilic cyclodextrins as enabling excipients for drug delivery and for decades of scientific collaboration: Tribute to a distinguished scientist, French representative and friend – A historical perspective

As a result of the long term collaboration and friendship between Prof. Dominique Duchene and Prof. Atilla Hıncal, several co-supervised Ph.D. theses were conducted in the frame of a co-tutelle PhD programme within the period of 2000–2007, based on the joint Ph.D. agreement between the Hacettepe University in Ankara, Turkey, and the Universite Paris XI in Chatenây-Malabry, France. The first of these scientific collaborations was based on the synthesis, characterization and evaluation of amphiphilic cyclodextrins as nanoparticulate material for the delivery of drugs with bioavailability problems, such as poor solubility, poor stability and side effects. This direct collaboration between Prof. Dominique Duchene and Prof. Atilla Hıncal was further followed on by different research teams from both universities, collaborating on brain delivery and ocular drug delivery with different polymeric nanoparticles resulting in two more Ph.D. theses and several publications. This paper is a historical perspective of this fruitful collaboration and acknowledges the support and supervision of the honorable Prof. Dominique Duchene in this scientific union between two countries and two universities.

Developments of the Belarussian Republic scientific and production union for powder metallurgy in the area of new materials and methods and their use in machine building

Today the Republic of Belarus is emerging as a region of skilled machine building, of developed chemical, petrochemical, light, and food industries, and electronics. Traditional products of the specialization of its industry are wheeled tractors, trucks, metal cutting tools, automatic lines, wrist-watches, motorcycles, television sets, computers, household refrigerators, bicycles, bearings, and electrical equipment. This determines the directions of scientific investigations in the area of powder metallurgy including the development of new materials and effective methods of production from them of parts of mechanisms, machines, equipment, etc. The start of development of powder metallurgy in the republic was the creation in 1957 of a special laboratory in the Department of Metals Technology of the Belorussian Polytechnic Institute. In 1980 there was formed the Belorussian Republic Scientific and Production Union for Powder Metallurgy, which included the Scientific-Research and Design Technology Institute for Powder Metallurgy (the head organization) and Molodechno Powder Metallurgy Plant. The path of development of power metallurgy in the republic was long and complex. For example, while in 1960 there were two areas in Belorussia with a total volume of production of about 20 tons of parts, in 1990 14 areas, shops, and a plant with a total volume of production of 8500 tons had been placed in service. In the territory of the republic alone more than 50 areas for the application of coatings have been created in recent years with the direct participation of the union. Today the primary directions in the activity of the union are development of the theoretical fundamentals of use of pulsed loads for creation of powder and composite materials with increase physicomechanical and functional properties, the development of new powder and composite materials and progressive methods of production from them of parts for machine building and other branches of technology with use of methods of static pressing, hot and cold forming, and sintering of freely poured powder, development of the theoretical fundamentals of application of protective coatings on machine and tool parts, and the development of equipment for accomplishment of them. As the result of training of engineering and scientific personnel in the Belorussian Polytechnic Institute (now the Polytechnic Academy) a well operating chain of scientific research-design and technology development-experimental production-industrial production-training of personnel has been established. In the union a broad range of materials which have found use in the machine building, radio and electronics, and electrical industries has been developed. To satisfy the requirements of industry Molodechno Powder Metallurgy Plant has started production of new forms of highly effective production such as blanks for electrical machinery commutators, gear hydraulic pump parts, friction parts, thermal tubes, and filters. New tribotechnical and constructional materials, coatings resistant to wear and corrosion, and porous materials are being developed. High-Density Constructional Materials and Parts of Powder Metallurgy Ferrous and Nonferrous Metals Produced with Use of Plastic Deformation of the Sintered Blanks. One of the effective methods of increasing the physicomechanical properties of ferrous and nonferrous metal-base powder metallurgy materials is plastic deformation of sintered powder metallurgy blanks in the cold condition and with heating. The essence of these processes is plastic flow of the sintered material under the action on it of external loads at normal or increased temperatures. This provides production of parts of the required

Moscow refusniks suffer over Nature letter to scientific union

Moscow refusniks suffer over Nature letter to scientific union

The role of Agricultural Economists in the Conservation of Natural Resources

In March 1 980 under the title World Conservation Strategy there appeared a statement of considerable international significance. This document was commissioned by the United Nations Environmental Programme (UNEP), which together with the World Wildlife Fund (WWF) provided the financial support for its preparation. Its production was essentially the responsibility of the International Union for Conservation and Natural Resources (IUCN), the views and approaches of which it is stated to express. According to the director-general of that scientific union:

Trends in the IUB

What is the IUB? Most scientific disciplines are represented on the international scene by a scientific union, the purpose of which is to assist the international, regional and local development of the science via any or all of several routes. 9 The opening Statute of the IUB reads that the Union aims to promote international cooperation in biochemistry, by means of research, discussion and publication, to promote high standards of biochemistry throughout the world and to promote international standardization of nomenclature. The unions, and there are eighteen, are joined together in the ICSU, which offers an umbrella for inter-union cooperation. All are non-governmental and nonpolitical. But where do the unions put down their roots? In the case of the IUB the members are the 'Adhering Bodies each of which represents a Scientific Community', where 'Scientific Community' is defined as being 'applicable to the biochemists of a country or of an otherwise defined geographical area that has an independent budget for scientific purposes'. These definitions, in which the words 'nation' or 'national' are deliberately not used, provided the formula whereby biochemists from all parts of China came to be represented in the IUB, by two Adhering Bodies (see E.C. Slater and W.J. Whelan, T I B S , February, 1980, pp. III-V). Biochemistry can take pride in offering a lead, subsequently adopted for the same purpose, by the Unions for chemistry (IUPAC) and astronomy (IAU) and to be adopted by the ICSU next month.

Increasing the quality and effectiveness of the equipment produced by the kislorodmash scientific and production union

Increasing the quality and effectiveness of the equipment produced by the kislorodmash scientific and production union

The functions of commission I of the international scientific radio union

The distinctive task of Commission I of the International Scientific Radio Union (URSI) is to extend the ability of all radio scientists to make valid measurements as a necessary means for the international exchange of scientific and engineering results. The Commission concentrates on: improved measurement methods applicable either to new phenomena or to closer tolerances for familiar phenomena, the highest national and international levels of accuracy, and progress for the long term. The Commission functions by surveying both progress and deficiencies in radio measurements and standards, by evaluating new results for their lasting contribution to the measurement structure of radio, by recommending the general adoption of proven advances and the pursuit of further research to remove deficiencies, and by giving its recommendations force and effect through the efforts of its members. A sketch of the international and national URSI organizations and operations is given. The functions are performed mainly by organizing technical meetings devoted to measurement and instrumentation, by encouraging pertinent publications, and by committee interactions with other international organizations having related interests. The organization has exerted significant impact on time and frequency standards, on international uniformity of radio standards, and on precision coaxial connectors as an aid to more accurate radio techniques.

The international scientific radio union—URSI

The history, purpose, and functioning of URSI, and the relationship of the United States National Committee of URSI to the IEEE, are described. A few examples demonstrating the interest of the Union in the field of this special issue of the PROCEEDINGS are given.