In this paper, principal component analysis is introduced to form a scene-based nonuniformity correction method for infrared focal plane arrays. The estimation of the gain and offset of the infrared detector and the correction of nonuniformity based on the neural network method with a novel estimation of desired target value are achieved concurrently. The current frame and several adjacent registered frames are decomposed onto a set of principal components, and then the first principal component is extracted to construct the desired target value. It is practical, forms fewer ghosting artifacts, and considerably promotes correction precision. Numerical experiments demonstrate that the proposed method presents excellent performance when dealing with clean infrared data with synthetic pattern noise as well as the real infrared video sequence.
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