In this study, spatial and temporal variations of spring compound dry and hot events (CDHEs) over northern Asia (NA) during 1950–2020 and the related possible mechanisms are investigated on the interannual timescale. The standardized compound event indicator (SCEI) is used to represent compound dry and hot conditions over NA, which is validated by the observed summer case of CDHEs over western Russia in 2010. The first empirical orthogonal function (EOF1) mode of the SCEI over NA presents a monopole pattern, while the EOF2 mode shows an east-west dipole pattern. Possible mechanism analysis indicates that the CDHEs tend to be modulated by local high-pressure anomalies, accompanied by reduced cloud cover and more solar radiation. The high-pressure anomalies can lead to warm temperature and water vapor divergence, which synergistically contributes to the occurrence of CDHEs. Further analysis shows that the EOF1 mode is jointly affected by the Scandinavian (SCAND) pattern and the Arctic Oscillation (AO); while the EOF2 mode is influenced by the Atlantic-Eurasian (AEA) teleconnection. Moreover, the North Atlantic tripolar pattern of sea surface temperature (SST) can influence the EOF1 mode through changing the AO. And the diagonal tripolar SST pattern over the North Atlantic affects the EOF2 mode via altering the AEA pattern. The influence of the SST patterns is further confirmed by numerical experiments using the Community Atmospheric Model version CAM-5.3.