Satisfactory Improvement Research Articles

Outcomes of Trochleoplasty versus Tibial Tubercle Osteotomy for Treatment of Patellar Instability Associated with Trochlear Dysplasia: A Systematic Review and Meta-analysis.

This study compared the outcomes of tibial tubercle osteotomy (TTO) and trochleoplasty for the treatment of patellar instability associated with trochlear dysplasia. This was a systematic review of the literature including published articles that describe either trochleoplasty or TTO in addition to medial patellofemoral ligament reconstruction for the surgical treatment of patellar instability associated with trochleoplasty. Main outcomes assessed were Kujala and International Knee Documentation Committee (IKDC) scores, in addition to recurrent instability and complications. Outcome measures reported were provided in a table format and a subjective analysis was performed. Ten studies were included with a total of 362 knees including 132 in the trochleoplasty group and 230 in the TTO group. Mean follow-up ranged from 27.6 to 61.3 months. At the final follow-up, both Kujala and IKDC scores improved significantly in all studies that reported both preoperative and postoperative scores in both groups. There was a total of three instability events in the trochleoplasty group as opposed to 21 in the TTO group. Both procedures, trochleoplasty and TTO, may provide satisfactory functional improvement in patients with patellar instability associated with trochlear dysplasia. However, trochleoplasty may be a better option to minimize the risk of recurrent instability. Level of evidence: level IV, systematic review of level III and level IV studies.

Antibiotic Resistance in Acne Treatment: Emerging Challenges and Implications for Dermatology Practice in Developing Countries like Bangladesh

Background: Antibiotic resistance in acne treatment is an escalating global issue, particularly in developing countries like Bangladesh, where misuse of antibiotics is prevalent. Objective: To assess the prevalence of antibiotic-resistant Cutibacterium acnes and its implications for acne treatment efficacy at Aurora Skin and Aesthetics in Dhaka, Bangladesh. Methods: A cross-sectional study was conducted from September 2021 to March 2022 at Aurora Skin and Aesthetics, Dhaka. A total of 100 acne patients were selected, and antibiotic sensitivity tests were performed on C. acnes strains isolated from lesion swabs. The data was analyzed to determine the resistance to commonly prescribed antibiotics like tetracyclines, erythromycin, and clindamycin. Results: Out of 100 patients, 45% were male and 55% were female. Among the isolated C. acnes strains, 60% showed resistance to erythromycin, 40% to clindamycin, and 35% to tetracyclines. A significant percentage (25%) of patients resisted more than one antibiotic. Patients with antibiotic-resistant acne exhibited a 30% longer treatment duration compared to non-resistant cases, with only 50% achieving satisfactory Improvement after 12 weeks of standard antibiotic therapy. Conclusions: The study highlights the growing problem of antibiotic resistance in acne treatment in Bangladesh, emphasizing the need for stricter antibiotic use guidelines and alternative therapies to improve treatment outcomes.

Physical activity and supplementation as alternative methods in migraine prophylaxis -literature review

Migraine is a common and debilitating neurological disorder. It is crucial to realize that migraines are distinguished from other types of headaches. People suffering from migraine are often unable to function normally, neglecting work and daily duties. The associated costs burden not only the patients but also their family and social life. What is more, many psychiatric comorbidities are common in migraine patients. Because of all these factors, preventive treatment is essential because it can decrease migraine frequency and improve quality of life. There are many preventative medications but satisfactory improvement in reducing the frequency of migraine attacks may not be achieved without modification of lifestyle including taking care of physical activity and supplementation. Many studies have shown that moderate physical activity and supplementation of vitamins B2, D, coenzyme Q10 and magnesium has a positive effect on reducing duration and frequency of the migraine attack.

Case Report: An Integrated Approach To Treating Infected Corneal Laceration With Traumatic Endophthalmitis In Paediatric Age Group

This case report presents a case of infected corneal laceration with traumatic endophthalmitis in a pediatric patient. A boy in his middle childhood sustained an ocular injury with scissors, resulting in a full-thickness corneal laceration and infection. Despite the delay in seeking treatment, the patient underwent successful surgical interventions, including corneal scraping, pars plana lensectomy, vitrectomy, and secondary intraocular lens implantation (IOL). The infection was managed with targeted antibiotics, and Staphylococcus aureus was confirmed as the causative organism. Remarkably, these efforts led to a satisfactory improvement in the patient’s vision to 20/50. This case underscores the importance of early intervention and a multidisciplinary approach in the management of pediatric ocular trauma to optimize outcomes.

Reversal Gene Expression Assessment for Drug Repurposing, a Case Study of Glioblastoma.

Glioblastoma (GBM) is a rare brain cancer with an exceptionally high mortality rate, which illustrates the pressing demand for more effective therapeutic options. Despite considerable research efforts on GBM, its underlying biological mechanisms remain unclear. Furthermore, none of the United States Food and Drug Administration (FDA) approved drugs used for GBM deliver satisfactory survival improvement. This study presents a novel computational pipeline by utilizing gene expression data analysis for GBM for drug repurposing to address the challenges in rare disease drug development, particularly focusing on GBM. The GBM Gene Expression Profile (GGEP) was constructed with multi-omics data to identify drugs with reversal gene expression to GGEP from the Integrated Network-Based Cellular Signatures (iLINCS) database. We prioritized the candidates via hierarchical clustering of their expression signatures and quantification of their reversal strength by calculating two self-defined indices based on the GGEP genes' log2 foldchange (LFCs) that the drug candidates could induce. Among eight prioritized candidates, in-vitro experiments validated Clofarabine and Ciclopirox as highly efficacious in selectively targeting GBM cancer cells. The success of this study illustrated a promising avenue for accelerating drug development by uncovering underlying gene expression effect between drugs and diseases, which can be extended to other rare diseases and non-rare diseases.

Niacinamide and sea daffodils-based bright healthy radiance product range for dark spots: a survey of Indian dermatologists' views and patient insights

Background: Niacinamide has demonstrated its ability to treat dark spots in various studies. The present study evaluated the perspectives and experiences of healthcare professionals (HCPs) and patients with the niacinamide and sea daffodils-based bright healthy radiance product range for dark spots. Methods: This study was part of a survey series focusing on various dermatology products across India. The study involved over 1000 registered HCPs including dermatologists, pediatricians, and cosmetologists nationwide. A total of 203 HCPs participated in the survey on the niacinamide and sea daffodils-based product range. A well-structured questionnaire with 15 questions was used to collect the data and the responses were recorded by the HCPs. Results: Out of the total of 1086 individuals who participated in the survey, majority were females (774, 71.2%). Most HCPs reported that nearly 15-30% of their patients present with dark spots. A vast majority of individuals reported extreme satisfaction with the use of niacinamide and sea daffodils-based bright healthy radiance product range (493, 45.5%) and rated its effectiveness as excellent (511, 47.2%). HCPs reported that most patients showed major improvement in skin brightness (529, 48.7%), while the rest of them (418, 38.4%; 137, 12.6%) experienced good and satisfactory improvement respectively. Importantly, an even skin tone was achieved in most of the patients (492, 45.8%) after the application of the product range. Conclusions: A personalized approach of using niacinamide and sea daffodil-based products according to the patient's skin types and skin conditions is essential to remove blemishes and dark spots and improve skin brightness.

Temporary Vocal Fold Augmentation Outcomes for Refractory Chronic Cough with Concurrent Nonparalytic Glottic Insufficiency due to Vocal Fold Atrophy

ObjectiveDetermine the effect of temporary vocal fold augmentation on refractory chronic cough in patients with glottic insufficiency due to vocal fold atrophy. MethodsRetrospective electronic chart review was conducted for patients with a diagnosis of bilateral vocal fold atrophy and refractory chronic cough undergoing vocal fold augmentation with carboxymethylcellulose. Patients with vocal fold immobility were excluded, and cough must have been present for at minimum 8 weeks. VHI-10, CSI, and RSI scores along with subjective overall patient report of chronic cough improvement were collected. ResultsA total of 28 patients underwent 30 vocal fold augmentation procedures with carboxymethylcellulose. All had undergone extensive cough work-up and treatment trials prior to their augmentation procedure. From chart review, 13 overall subjectively reported satisfactory improvement in their cough, 5 reported partial improvement, and 7 reported no improvement in their cough. An uncertain effect on cough was documented in 5 (either patient was uncertain or no mention of cough symptom in the interval chart history note). For those subjects with both pre- and post-augmentation data, mean pre-augmentation CSI: 22.08 + 6.8 (n=13); VHI-10: 13.6 + 8.9 (n=18); RSI: 22.4 + 7.5 (n=17). Mean post-augmentation CSI was 20.7 + 9.2 (n=13); VHI-10: 15.2 + 8.2 (n=18); RSI: 21.1 + 5.8 (n=17). Mean pre-post change in CSI was -1.4 + 5.1 (p=0.175, n=13, range -10 – +6). ConclusionsVocal fold augmentation seems to provide subjective cough improvement in some patients with concurrent glottic insufficiency due to vocal fold atrophy and refractory chronic cough. It can be offered as a diagnostic trial, on which further augmentation may be offered, for patients with persistent cough despite prior work-up and treatment trials. Further controlled prospective studies are needed to identify factors that are predictive of successful cough improvement following vocal fold augmentation, as well as the effect of durable augmentation in those patients who had improvement with a diagnostic trial.

PEMBINAAN DALAM MENGENALI DAN MENYELESAIKAN SOAL-SOAL OLIMPIADE MATEMATIKA TINGKAT NASIONAL DI SMA IT AL-KAMAL NW NARMADA

The purpose of this service is to improve the abilities and skulls of the coach teacher in analyzing and solving math Olympiad questions, the Olympiad coach teacher can transfer this knowledge to students and orther teacher friends in their respective school environments. To prepare superior and outstanding student nasional Olympiads. The coaching methods is carried out by brainstorming methods (opinions sharing), Lecture methods, problem solving simulation methods (problem solving), and discussion methods. The expected results are that the participants take part in coaching and the Head of SMA IT Al-Kamal Narmada and the team implementing the Olympic activites hope that the lecturers, especially from Hamzanwadi Selong University and Muhammadiyah Bima University, are willing to provide intensive coaching to the participants. Satisfactory improvement can also be seen from the presentasion of material and discussion of Olympic questions which were well digested by the participants.

Upgrading the dynamic mathematical model of temperature sensors in gaseous media for low Biot number (Bi < 0.1)

A mathematical model incorporating the transient response of NTC thermistors is presented. The internal thermal conduction resistance of the sensor relative to the thermal convection resistance of the medium results in a low Biot number Bi<0.1, yielding a fast dynamic response in gaseous media. This is advantageous in applications requiring minimal fluid interaction. However, negligible energy exchanges occur, introducing measurement uncertainty and ignoring the behavior of the measuring instrument. Therefore, this work proposes an improvement strategy for the mathematical model of these sensors, complementing the conventional model based on the concept of time constant. The strategy considers the heat flow through the thermistor wires in the energy balance, assuming they are semi-infinite solids and applying an approximation to the heat flow formula. Satisfactory improvement results were obtained compared to the conventional model, based on controlled laboratory tests with various gases.

Ayurvedic Interventions in Motor Neuron Disease

Motor neurons are the neurons through which the brain exerts control over skeletal muscles of the body. Motor neuron diseases are rare heterogeneous group of neurologic disorders characterized by progressive degeneration of motor neurons. A 55-year-old woman diagnosed as motor neuron disease was admitted to Vaidyaratnam Ayurveda College Hospital, on 2/11/2023, for a 21 day duration, presenting with complaints of weakness of both upper limbs associated with muscle wasting predominantly on right shoulder and wrist since 1 year. The clinical and laboratory features suggested a diagnosis of brachial amyotophy diplegia, a regional variant of ALS. According to Ayurveda, Avarana vatavyadhis are found to have close resemblance to Motor Neuron Diseases and her symptomology can be correlated to Kaphavruta Vyanavata. The patient underwent Avaranagna and Vata vyadhi chikitsa. Assessment of the patient was done before and after treatment by physical examination, ALSFRS-R and Neuro QoL scale. A satisfactory improvement was observed with gradual gaining of upper limb strength and quality of life. This case study demonstrates that brachial amyotophy diplegia can be symptomatically managed with Ayurvedic therapy.

Congenital Fibrosis of Extraocular Muscles: A Retrospective Study of 76 Patients.

Background Congenital fibrosis of the extraocular muscles (CFEOM) is a non-progressive sporadic or familial disease characterized by abnormal innervation of the extraocular muscles. This study aims to evaluate the types of diseases, management steps, and surgical outcomes. Methodology A total of 76 patients diagnosed with CFEOM between 2000 and 2022 were evaluated retrospectively. Patients were divided into CFEOM 1, 2, or 3 based on clinical findings. Preoperative and postoperative ocular deviations, as well as abnormal head positions (AHPs), of the patients were evaluated. Excellent outcomes for the head position were defined as less than 5°, good as less than 10°, and poor as greater than 10°. Excellent alignment for strabismus was considered to be less than 10 prism diopters (PD), good as less than 20 PD, and poor as greater than 20 PD. Results The average age at the first surgery in our clinic was 11.6 (1-51) years. The mean follow-up was 28.6 ± 7.4 months (range = 4-56 months). Type 1 disease was detected in 48 (63.2%) patients, type 2 disease in eight (10.5%), and type 3 disease in 20 (26.3%) patients. Of the 49 patients with AHP, 20 achieved excellent outcomes, 17 had good outcomes, and the remaining had poor outcomes. Ocular alignment in the primary position following the latest surgery was excellent in 30 patients, good in 26 patients, and poor in 20 patients. Conclusions No single best surgical method can be universally applied to every patient diagnosed with CFEOM. Patients must be evaluated individually and carefully, and the appropriate surgical procedure must be chosen. In this way, satisfactory gaze alignment and improvement of the AHP can be achieved.

Production and mechanical characterization of Carbon fiber laminated composites modified by Graphene nano platelets (GnP) for high performance application

Polymeric materials play a pivotal role in diverse high-performance engineering domains, including aerospace, marine, automotive, and defense sectors. Their applications span from essential protective gear to intricate components vital for aircraft missiles, showcasing their versatility and significance in modern technology. The Graphene nano platelets (GnP) have the exceptional properties of a high contact area with the reinforcement material and enhanced synergistic effect, which is highly desired to improve the material performance. The present work describes the production of Carbon fiber laminated composites enhanced by Graphene nano Platelets (GnP) using a cost-effective Hand layup method (HLM). Herein, three different concentrations of GnP at 0.25, 1.0, and 1.75 wt% were used to modify the CFRP laminates. This is primarily performed to examine the viscoelastic and mechanical properties of the proposed GnP/CFRP sample. The findings of mechanical testing reveal that GnP nanofiller addition of 1.00 wt% significantly enhances the tensile and flexural properties by 20.7% and 10.05% respectively in comparison to neat sample. Also, the composites show satisfactory improvement in impact strength by 31.60% and enhanced viscoelastic properties at a 0.25 wt% of GnP loading. The XRD and DMA findings support GnP loading for high performance applications.

Extraforaminal Microdiscectomy for Upper Lumbar Disc Herniations: A Minimally Invasive Alternative Surgical Approach

BackgroundVarious methods and techniques have been developed for extraforaminal decompression, particularly for far lateral lumbar disc herniation. Distinct anatomical differences are noticeable in the upper levels of the lumbar spine, which may complicate the related surgical approach. This study aimed to determine the safety and efficiency of the far lateral extraforaminal approach for the upper lumbar disc. MethodsL1–2 and L2–3 migrated lumbar disc herniations were defined as upper lumbar disc herniations. Thirty-one consecutive patients with upper lumbar disk herniation who underwent extraforaminal lumbar microdiscectomy between January 2018 and March 2022 were retrospectively investigated. The patients were assessed using the interval history, follow-up lower back and leg pain visual analog scale scores (0–100 mm), the Oswestry Disability Index (%), and modified MacNab criteria. ResultsThirty-one consecutive patients with upper lumbar disk herniation (20 men and 11 women) with a mean age of 52.8±10.8 years (range 31–70 years) underwent extraforaminal lumbar microdiscectomy. The preoperative and postoperative visual analog scale scores and ODI were significantly different (P < 0.001). According to the modified MacNab criteria, 23 patients showed excellent improvement, 5 showed good improvement, and 3 showed fair improvement; thus, the rate of satisfactory improvement was 90.3% at the 2-year follow-up. No patients required reoperation at the operative level during follow-up. ConclusionsExtraforaminal lumbar microdiscectomy is a safe and effective minimally invasive surgical technique for treating upper lumbar disc herniation.

Enhancing Clarity and Patient Safety: Evaluating the Inclusion of Laterality in Orthopaedic Outpatient Correspondence in Galway, Ireland.

Background In medical documentation, accurate mention of laterality, whether a condition or treatment pertains to the left or the right side of the body, is critical for avoiding errors like wrong-site surgeries, which can have severe repercussions. This study aims to assess compliance regarding the mention of laterality in outpatient clinic letters at Galway University Hospital. Methods An analytical cross-sectional study was conducted at Galway University Hospital from February to August. We reviewed outpatient letters in the Orthopaedic Department. The Fisher exact and Chi-square tests were employed to observe the association between the levels of practitioners and laterality. Results A total of 278 outpatient letters from 37 practitioners in one week were analyzed. The overall laterality rate was 65.1%.It was observed that there was a male predominance in the workforce (31; 83.8%). Conclusion In conclusion, our study revealed satisfactory improvement in the prevalence of mentioning laterality among healthcare providers. It is recommended that educational sessions and re-auditing be carried out to enhance the quality of care.

The use of acupuncture in the treatment of lumbar intervertebral disc herniation (сlinical case)

Abstract. The effectiveness of acupuncture in the treatment of discogenic compression radiculopathy has been proven in many scientific works. Acupuncture has a positive effect not only on the course of radiculopathy, but also on the size of the hernias and protrusions of the intervertebral discs themselves. Purpose. To study the effectiveness of acupuncture in the treatment of intervertebral disc herniation in the lumbar region. Material and methods. Before and after treatment (after 3 and 6 months), the patient was assessed: neurological status, results of an electrokymographic study of peripheral nerves of the lower extremities, MRI of the spine. Acupuncture was carried out at acupuncture points of the meridian of the stomach, bladder, gallbladder, colon, for a course of 40 procedures. Results. A 40‑year-old patient suffered from prolonged pain for 8 months. Conservative treatment with drug therapy and physical therapy did not provide satisfactory improvement in symptoms. On MRI of the PC department, the IVD herniation at the L4 — L5 level was 12 mm. When using acupuncture, the pain syndrome decreased clearly after the first sessions. Sensory disturbances and motor deficits gradually regressed. After 40 sessions over 3 months, electromyographic indicators of the affected right peroneal nerve improved. An unexpected result was a reduction in the size of the IVD hernia by 50 % to 6 mm.

Effects of additional exercise therapy after a successful vascular intervention for people with symptomatic peripheral arterial disease.

Effects of additional exercise therapy after a successful vascular intervention for people with symptomatic peripheral arterial disease.

The Long-term Efficacy of Total Knee Arthroplasty on End-stage Kashin-Beck Disease of the Knee in Highland Tibetan Areas Patients: A Retrospective Study with 10-Year Follow-up.

Despite the established success of total knee arthroplasty (TKA) with end-stage osteoarthritis, there is a notable scarcity of research on its long-term outcomes in individuals suffering from end-stage Kashin-Beck disease (KBD). This retrospective study aimed to assess the long-term outcomes and effectiveness of clinical function, quality of life, and complications of TKA and end-stage KBD patients in Tibetan highland areas. The retrospective cohort included 43 KBD patients, comprising a total of 59 knees, who had undergone TKA at West China Hospital, Sichuan University between 2008 and 2021. Patients were subsequently followed up for a minimum of 3 years, and received rigorous radiological and clinical assessments at 3, 6, and 12 months post surgery, followed by annual examinations thereafter. The evaluation included various efficacy indices, including visual analogue scale (VAS) scores, hospital for special surgery (HSS) scores, functional score for adult Tibetans with Kashin-Beck disease (FSAT-KBD), and radiographic findings. Comparison of indicators within the same group was conducted using one-way repeated-measures analysis of variance or paired sample t-tests, whereas between-group differences were compared using an independent t-test. Throughout the average follow-up duration of 10.8 years, patients experienced a substantial reduction in knee pain and noteworthy functional improvement. The VAS scores decreased significantly from 77.47 ± 4.12 mm before surgery to 10.91 ± 1.97 mm after surgery, indicating considerable alleviation of knee pain. The HSS scores improved markedly, increasing from 44.26 ± 4.95 preoperatively to 91.26 ± 4.37, indicating enhanced joint function. Similarly, the FSAT-KBD exhibited positive progression, increasing from 25.90 ± 3.12 to 36.95 ± 3.54. Importantly, at the last follow-up, none of the patients presented with periprosthetic infection, prosthesis loosening, or periprosthetic fracture. At long-term follow-up, compared with patients in the preoperative period, patients in Tibetan highland areas with KBD of the knee who underwent TKA benefited from a significant reduction in pain, improvement in joint function, and satisfactory improvement in quality of life.

Trends Favoring an Anatomical Approach to Radiofrequency Catheter Ablation of Idiopathic Ventricular Arrhythmias Originating From the Left Ventricular Summit.

Epicardial radiofrequency catheter ablation (RFCA) of idiopathic ventricular arrhythmias (VAs) originating from the left ventricular summit (LVS) is challenging because of the anatomic barriers. On the other hand, RFCA at the endocardial sites near the earliest epicardial activation site of LVS-VAs (anatomic approach) has proven successful. The evolving trends in the approaches and outcomes of RFCA of LVS-VAs at a single center were evaluated. We studied 88 consecutive patients with idiopathic LVS-VAs at our institute from 2009 to 2019. These patients were divided into 3 periods: 2009 to 2012 (early), 2013 to 2015 (middle), and 2016 to 2019 (recent). The data were compared among the 3 periods. The RFCA success rate did not significantly change from the early to middle period but significantly increased from the middle to recent period (P=0.0315). The transpericardial approach usage significantly decreased over the 3 periods. The anatomic approach usage significantly increased over the 3 periods. The use of the transpericardial approach did not affect the RFCA outcomes over the 3 periods. The success rate of the anatomic RFCA tended to increase from the early to middle period and significantly increased from the middle to recent period (P=0.0412). The number of endocardial locations where RFCA was successful increased over the 3 periods. Over the 10-year period, the transpericardial approach became decreasingly performed, whereas the anatomic approach became increasingly performed with a satisfactory improvement in the RFCA outcomes of LVS-VAs. The anatomic RFCA became more successful by identifying more and various endocardial locations as target sites.

Poor postoperative pain control is associated with poor long-term patient-reported outcomes after elective spine surgery: an observational cohort study

BACKGROUND CONTEXTA significant proportion of patients experience poorly controlled surgical pain and fail to achieve satisfactory clinical improvement after spine surgery. However, a direct association between these variables has not been previously demonstrated. PURPOSETo investigate the association between poor postoperative pain control and patient-reported outcomes after spine surgery. STUDY DESIGNAmbispective cohort study. PATIENT SAMPLEConsecutive adult patients (≥18-years old) undergoing inpatient elective cervical or thoracolumbar spine surgery. OUTCOME MEASUREPoor surgical outcome was defined as failure to achieve a minimal clinically important difference (MCID) of 30% improvement on the Oswestry Disability Index or Neck Disability Index at follow-up (3-months, 1-year, and 2-years). METHODSPoor pain control was defined as a mean numeric rating scale score of >4 during the first 24-hours after surgery. Multivariable mixed-effects regression was used to investigate the relationship between poor pain control and changes in surgical outcomes while adjusting for known confounders. Secondarily, the Calgary Postoperative Pain After Spine Surgery (CAPPS) Score was investigated for its ability to predict poor surgical outcome. RESULTSOf 1294 patients, 47.8%, 37.3%, and 39.8% failed to achieve the MCID at 3-months, 1-year, and 2-years, respectively. The incidence of poor pain control was 56.9%. Multivariable analyses showed poor pain control after spine surgery was independently associated with failure to achieve the MCID (OR 2.35 [95% CI=1.59–3.46], p<.001) after adjusting for age (p=.18), female sex (p=.57), any nicotine products (p=.041), ASA physical status >2 (p<.001), ≥3 motion segment surgery (p=.008), revision surgery (p=.001), follow-up time (p<.001), and thoracolumbar surgery compared to cervical surgery (p=.004). The CAPPS score was also found to be independently predictive of poor surgical outcome. CONCLUSIONPoor pain control in the first 24-hours after elective spine surgery was an independent risk factor for poor surgical outcome. Perioperative treatment strategies to improve postoperative pain control may lead to improved patient-reported surgical outcomes.

Management of Artavakshaya along with Dhatukshaya in lean adolescent girls: a narration

Abstract Background: Artavakshaya (~scanty menstruation/hypomenorrhea/oligomenorrhea) is one of the most prevalent reproductive disorders among adolescent girls now. Irregular, delayed and scanty menstruation, abdominal cramping, and lower back pain are the major symptoms of Artavakshaya. The condition can be correlated with oligomenorrhea along with hypomenorrhea based on similar symptomatology. Poor nutrition, stress, hormonal disturbance, and unhealthy lifestyle are the major causes of oligomenorrhea along with hypomenorrhea particularly in lean adolescent girls. Aim and Objective: This study aims to evaluate the efficacy of Ayurveda protocol in the management of Artavakshaya in adolescent girls. The rationale behind this study was only to prevent further gynecological morbidities and cure the current condition. Materials and Methods: An unmarried female patient of 14 years of age came to the outpatient department of Prasuti Tantra and Stree Roga of Sumandeep Ayurved Medical College &amp; Hospital with chief complaints of irregular, delayed, and scanty menstruation associated with weakness and white discharge per vagina for one and half year. The patient was assessed and diagnosed with subjective criteria for menstrual abnormalities, a pictorial chart for assessment of menstrual blood, and a Visual Analog Scale. The condition was managed with Rasapachaka syrup and Saptamrita Mishrana along with lifestyle modification and Rajaswala Paricharya (~do’s and don’ts during menstrual days). The treatment lasted for 3 months and the patient was followed up for the next 1 month. Results: The findings revealed satisfactory improvement after treatment. Conclusion: The findings revealed that Artavakshaya in lean adolescent girls could be managed effectively with these Ayurveda regimens and other modern interventions avoided.