You have accessJournal of UrologyKidney Cancer: Evaluation and Staging III1 Apr 2015MP50-15 EVALUATION OF DE NOVO HYPERTENSION AFTER ROBOTIC PARTIAL NEPHRECTOMY: A SINGLE CENTER ANALYSES Oktay Akca, Homayoun Zargar, Peter Caputo, Daniel Ramirez, Riccardo Autorino, Luis Felipe Brandao, Humberto Laydner, Hiury Andrade, Robert J. Stein, and Jihad H. Kaouk Oktay AkcaOktay Akca More articles by this author , Homayoun ZargarHomayoun Zargar More articles by this author , Peter CaputoPeter Caputo More articles by this author , Daniel RamirezDaniel Ramirez More articles by this author , Riccardo AutorinoRiccardo Autorino More articles by this author , Luis Felipe BrandaoLuis Felipe Brandao More articles by this author , Humberto LaydnerHumberto Laydner More articles by this author , Hiury AndradeHiury Andrade More articles by this author , Robert J. SteinRobert J. Stein More articles by this author , and Jihad H. KaoukJihad H. Kaouk More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.02.2926AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES The kidney plays an important role in regulating arterial blood pressure. The aim of this study is to evaluate development of de novo hypertension (HT) in patients who underwent robotic partial nephrectomy (RPN). Further we aimed to identify potential patient and surgery related factors that may contribute to HT after RPN. METHODS Our RPN database of 665 patients, between May 2007 and May 2013, was retrospectively assessed to identify patients with no history of previous HT. This cohort was divided into patient who remained normotensive and patients who developed de-novo HT after surgery. We compared these two groups in terms of demographics, tumor characteristics, perioperative and postoperative findings. RESULTS We identified 211 patients with no HT before RPN surgery. Postoperatively, 34 (16.1%) developed de-novo HT. The use of anti-lipid drug therapy prior to surgery (P=0.016), hospital stay (P=0.03) and use of Satinsky clamp (P=0.001) were significantly different between the two groups. After multivariable analysis, body mass index (BMI) (OR 1.07 (95%CI (1.01,1.14); p=0.04), use of anti-Lipid drugs (OR 2.7 95%CI (1.07,6.67); p=0.03) and use of Satinsky clamp (OR 2.9 95%CI (1.02,8.34); p=0.04) were found to be independent risk factors associated with the development of HT. CONCLUSIONS Patients undergoing RPN may be at risk for the development of HT. Lifestyle and surgical technique may play an important role in the development of de novo HT following RPN. This study identifies BMI and the use of anti-lipid medications as lifestyle dependent factors and the use of Satinsky clamp as a surgical dependent factor for the development of de novo HT following RPN. Comparison of demographics, perioperative findings and postoperative outcomes between Hypertensive and Non-Hypertensive patients Non-Hypertensive De Novo Hypertensive P Patient Number 177 (83.9%) 34 (16.1%) - Age, Mean±SD (years) 49.6±12 53.5±13.6 0.09 BMI, Mean±SD (kg/m2) 28.1±5.8 30±7.3 0.1 ASA, Median (IQR) 2 (2-3) 2 (2-3) 0.7 Pre-Op eGFR, Median (IQR) (mL/min/1.73 m2) 92.8 (83.7-105.9) 90.1 (76.6-107.9) 0.43 DM, n (%) 33 (18.6) 7 (20.8) 0.79 Anti-Lipid Drug Before Surgery 34 (19.2%) 13 (38.2%) 0.016 Renal Score Median (IQR) 7 (5-9) 8 (6-9) 0.46 WIT, Median (IQR) (min) 20 (16-25) 21 (17-28) 0.36 Venous Clamping, N (%) 110 (62.1) 27 (79.4) 0.059 Satinsky, N (%) 31 (17.5) 15 (44.1) 0.001 eGFR preservation 1 year % (IQR) 88.7 (89.2-96.7) 83.5 (69.6-99) 0.22 Time to DeNovo HT Developed, Median (IQR) Days - 373 (130-1118) - © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 4SApril 2015Page: e616-e617 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Oktay Akca More articles by this author Homayoun Zargar More articles by this author Peter Caputo More articles by this author Daniel Ramirez More articles by this author Riccardo Autorino More articles by this author Luis Felipe Brandao More articles by this author Humberto Laydner More articles by this author Hiury Andrade More articles by this author Robert J. Stein More articles by this author Jihad H. Kaouk More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...