Aeolian sandstones are capable of forming excellent reservoir rock due to their textural and compositional maturity. Often spanning across large areas, such formations may however experience spatial variability in burial and temperature exposure potentially leading to a heterogeneous diagenesis and subsequent reservoir quality. To assess such potential variability, this case study focusses on the diagenesis of the aeolian units of the Lower Jurassic Etjo Formation in Namibia, exposed at three key localities lying >100 km apart from each other. The Etjo Formation has experienced two major burial phases controlled by the emplacement of (I) Jurassic Karoo and (II) Lower Cretaceous Paraná-Etendeka volcanic rocks separated by an intervening exhumation phase. Petrographic analysis reveals very different rock properties between the localities with respect to intergranular volumes (IGV), intensity of quartz cementation, and preserved porosities. Average IGV and quartz cement values are 30.7 % and 24.3 % at Gamsberg, 23.7 % and 6.5 % at Waterberg and 19.7 % and 15.4 % at Mt. Etjo. Point-counted intergranular porosity values are on average 2.6 % (Gamsberg), 10.8 % (Waterberg), and 1.5 % (Mt. Etjo). Waterberg samples had an on average 72 % larger nucleation surface area available for quartz cement growth than samples from Mt. Etjo. The higher quartz cement volumes at Mt. Etjo therefore argue for a higher thermal exposure than at Waterberg. This is supported by kaolinite-to-illite transformation only occurring at Mt. Etjo. We attribute the higher temperature signature to the proximity of Mt. Etjo to the center of lower Cretaceous Paraná-Etendeka volcanism and related elevated thicknesses of the lava pile or heat flow increase. At Gamsberg, there is evidence for a quartz cement generation that formed during the Jurassic. This earlier cement stabilized the grain framework and preserved the IGV during the following Etendeka burial event. The Etjo Formation provides an exceptional example for the wide range of very low to very high degrees of compaction and cementation that can occur within an otherwise homogeneous, texturally and compositionally mature sandstone formation. This study underscores the importance of accounting spatial variations in burial depths and temperatures when predicting the diagenetic properties of reservoir rocks.