Safe Utilisation Research Articles

Tuneable mesoporous silica material for hydrogen storage application via nano-confined clathrate hydrate construction

Safe storage and utilisation of hydrogen is an ongoing area of research, showing potential to enable hydrogen becoming an effective fuel, substituting current carbon-based sources. Hydrogen storage is associated with a high energy cost due to its low density and boiling point, which drives a high price. Clathrates (gas hydrates) are water-based (ice-like) structures incorporating small non-polar compounds such as H2 in cages formed by hydrogen bonded water molecules. Since only water is required to construct the cages, clathrates have been identified as a potential solution for safe storage of hydrogen. In bulk, pure hydrogen clathrate (H2O-H2) only forms in harsh conditions, but confined in nanospaces the properties of water are altered and hydrogen storage at mild pressure and temperature could become possible. Here, specifically a hydrophobic mesoporous silica is proposed as a host material, providing a suitable nano-confinement for ice-like clathrate hydrate. The hybrid silica material shows an important decrease of the pressure required for clathrate formation (approx. 20%) compared to the pure H2O-H2 system. In-situ inelastic neutron scattering (INS) and neutron diffraction (ND) provided unique insights into the interaction of hydrogen with the complex surface of the hybrid material and demonstrated the stability of nano-confined hydrogen clathrate hydrate.

SynD: Australian synthetic health data community of practice

ObjectivesThe current workflow for health data research in Australia is inefficient. After funding is secured, researchers often face delays of months or years to access the necessary data. Synthetic data could significantly improve the pace and impact of health data research but lacks foundational infrastructure. We aim to develop this infrastructure and support the use of synthetic data to improve data access and research quality across Australia. ApproachWe held two workshops with Australian groups working on synthetic data. The format included participant updates and invited talks on international approaches to synthetic data and health data research. Workshops collected use cases and stimulated discussion on national collaboration. A facilitator then led thematic analysis to draft a consensus roadmap and terms of reference towards national synthetic data infrastructure. ResultsWe recruited 18 participants. Participants were cross sectoral: universities (9), research funding bodies (5), state health departments (4). Represented six states and territories: Queensland (6), New South Wales (3), Victoria (3), Western Australia (3), Australian Capital Territory (2), South Australia (1). Gender: women (11), men (7). The roadmap includes stakeholder engagement, a governance framework, and training events. ConclusionSynD is an Australian community of practice for synthetic health data. Our mission is to unlock the value of health information through synthetic data to advance research, education, innovation and service delivery within the health and care sector. This collaborative effort should ensure a harmonised approach to the safe and effective utilisation of synthetic data to enhance health outcomes across Australia.

412.2: Favourable outcomes of recipients of SARS-CoV-2 RNA positive donor organs support their safe utilisation in the post-pandemic era.

412.2: Favourable outcomes of recipients of SARS-CoV-2 RNA positive donor organs support their safe utilisation in the post-pandemic era.

Trace amine associated receptor 1: predicted effects of single nucleotide variants on structure-function in geographically diverse populations

Trace Amine Associated Receptor 1 (TAAR1) is a novel pharmaceutical target under investigation for the treatment of several neuropsychiatric conditions. TAAR1 single nucleotide variants (SNV) have been found in patients with schizophrenia and metabolic disorders. However, the frequency of variants in geographically diverse populations and the functional effects of such variants are unknown. In this study, we aimed to characterise the distribution of TAAR1 SNVs in five different WHO regions using the Database of Genotypes and Phenotypes (dbGaP) and conducted a critical computational analysis using available TAAR1 structural data to identify SNVs affecting ligand binding and/or functional regions. Our analysis shows 19 orthosteric, 9 signalling and 16 micro-switch SNVs hypothesised to critically influence the agonist induced TAAR1 activation. These SNVs may non-proportionally influence populations from discrete regions and differentially influence the activity of TAAR1-targeting therapeutics in genetically and geographically diverse populations. Notably, our dataset presented with orthosteric SNVs D1033.32N (found only in the South-East Asian Region and Western Pacific Region) and T1945.42A (found only in South-East Asian Region), and 2 signalling SNVs (V1253.54A/T2526.36A, found in African Region and commonly, respectively), all of which have previously demonstrated to influence ligand induced functions of TAAR1. Furthermore, bioinformatics analysis using SIFT4G, MutationTaster 2, PROVEAN and MutationAssessor predicted all 16 micro-switch SNVs are damaging and may further influence the agonist activation of TAAR1, thereby possibly impacting upon clinical outcomes. Understanding the genetic basis of TAAR1 function and the impact of common mutations within clinical populations is important for the safe and effective utilisation of novel and existing pharmacotherapies.

Modification and activation of hydrochar obtained by the hydrothermal carbonisation process of invasive plant biomass

Invasive plants produce significant amounts of biomass and their spreading are one of the major factors influencing biodiversity. This article demonstrates the possibilities of hydrothermal carbonisation (HTC) for the treatment of invasive Sosnowsky's hogweed biomass to achieve its safe utilisation simultaneously producing new sorbent materials. Two different N-doping methods of hydrochar (HC) including impregnation and HTC approaches, followed by activation, and three oxidation approaches like cold KOH activation, Fenton's oxidation and UV treatment have been evaluated to obtain the perspective material for carbon capture and environmental technologies. The most optimal oxidation approach to obtain adsorbent for environmental technologies was HCs cold activation with KOH, which provides high sorption capacities concerning metallic ions and organic substances (Cu 18 mg/g, and methylene blue 146 mg/g). Evaluating various N-doping approaches, the highest CO2 adsorption capacity was obtained for impregnated samples, that were thermally activated using KOH, reaching up to 3.9 mmol/g.

Co-enrichment of selenium and cadmium in soils of southern China and its implication for the safe utilisation of selenium-rich lands

Dietary deficiency of selenium (Se) is a global health threat related to low Se concentrations in crops. Southern China has abundant Se-rich land resources, but the cadmium (Cd) pollution problem is prominent, which may lead to Cd exceeding the safety standard in Se-rich crops. Therefore, it is important to delineate Se-rich land without Cd pollution in order to develop green Se-rich agriculture. Based on soil/sediment geochemical survey data covering 2.3 million km2 of southern China, this study analysed the concentration and spatial distribution of Se and Cd, discussed their enrichment mechanisms and proposed suggestions for the safe use of Se-rich land. The results showed that the soil/sediments in southern China were significantly enriched in Se and Cd, and the median values were 0.31 mg·kg−1 and 221 μg·kg−1, which were 1.8 times and 2.5 times the national soil background values, respectively. In addition, a significant positive correlation was observed between Se and Cd, indicating that Cd contamination in Se-rich soils frequently exceeded the pollution limit. According to statistics, Se-rich land accounted for 32.13 % of southern China. However, due to the co-enrichment of Se and Cd, areas without Cd pollution accounted for only one-third of the total Se-rich area. In particular, the areas with co-enrichment of SeCd are primarily distributed in Yunnan, Guizhou, Guangxi, western Hubei, northwestern Zhejiang, western Hunan, southern Hunan and northern Guangdong. The enrichment of Se is predominantly associated with parent rocks (black and carbonate rocks). At the same time, the enrichment of Cd is influenced by the parent rocks and PbZn mineralisation and mining activities. Three recommendations for managing Se-rich land were proposed: imposing restrictions on the utilisation of heavily contaminated Se-rich land for agricultural production, adopting a rational approach towards utilising lightly polluted Se-rich land and actively promoting the development of Se-rich agriculture in uncontaminated Se-rich areas. In the future, it is necessary to develop technologies that simultaneously enhance Se absorption while inhibiting Cd absorption in order to safely exploit Se-rich lands affected by Cd pollution.

Prescription practices for antipsychotic medication in an acute inpatient ward: Risks / benefits discussions with patients and performance of baseline investigations as per NICE guidelines

IntroductionAntipsychotic medications are essential for managing psychiatric disorders, offering symptom relief and improved functioning. However, their use carries potential risks. Vigilant monitoring and patient engagement are crucial when initiating antipsychotics.ObjectivesTo explore whether comprehensive discussions with patients concerning the benefits and risks of antipsychotics are taking place, and whether baseline investigations are performed before initiation of antipsychotics as per NICE guidelines.MethodsThis retrospective study focused on admissions to a male acute ward between March 1 and May 31, 2023. Data from electronic patient records included demographics, Mental Health Act (MHA) status, psychiatric diagnoses, medical co-morbidities, documentation of medication benefits / side effects discussions with patients, medication information provision, as well as baseline investigations involving weight, height, waist/hip circumference, pulse, blood pressure, blood glucose, HbA1c, lipid profile, prolactin levels, movement disorder assessment, nutritional status, diet, physical activity, and ECG.ResultsAmong 23 admitted patients, 15 were newly initiated or reintroduced to antipsychotics, with 14(93.3%) admitted under the MHA. Primary diagnoses included Paranoid Schizophrenia (33.33%), Unspecified Non-Organic Psychosis (20%), Bipolar Affective Disorder (20%), and others. Medical comorbidities were observed in 10(66.7%), notably type 2 diabetes (40%). Among initiates, 6(40%) were new to treatment, while in 9(60%) it was re-initiated.Within the 15-patient group, discussions on treatment benefits engaged 11(73.3%), while 4(26.7%) lacked complete documentation. Only 6(40%) had discussions about side effects. Metabolic side effects were discussed with 3(20%), extrapyramidal effects with 2(13.33%), while 4(26.7%) had general side effect talks. Patient information leaflets were given to 5(33.3%) patients. Baseline measurements: 12(80%) had weight/height, 4(26.7%) waist/hip, and 14(93.3%) pulse/blood pressure assessed. Blood tests were declined by 4(26.7%). Baseline glucose, HbA1c, lipids, and prolactin were assessed in 8(53.3%), 10(66.7%), 9(60%), and 8(53.3%) patients respectively. Nutritional status was assessed in 13(86.7%), movement disorders in 1(6.7%), and physical activity in 1(6.7%). All 15(100%) patients were offered ECGs, although 5(33.3%) declined.ConclusionsAdherence to NICE guidelines for baseline investigations and risk/benefit discussions prior to antipsychotic initiation was low, apart from ECGs, weight/height, pulse/blood pressure, assessment of nutritional status, and discussions about antipsychotics’ benefits. Implementing effective monitoring and patient engagement to mitigate potential side effects, is crucial to facilitating the safe and efficient utilisation of antipsychotics.Disclosure of InterestNone Declared

Public awareness on the rationale consumption and appropriate disposal methods of unused and expired medications in Kanchipuram district, Tamilnadu, India

Background/Aim: Improper drug disposal methods are a threat to the nature and its ecosystem by accumulation of active compounds included in these pharmaceuticals. Aim of this study was to assess the knowledge, attitude and practice (KAP) on the rationale consumption and appropriate disposal methods of unused and expired medications among common public in Kanchipuram district, Tamilnadu, India. Method: KAP questionnaire was prepared to get responses from all participants who had volunteered for the study. Questionnaire had queries pertaining to the personal information about the respondent and respondent's knowledge, practice and attitude concerning drug usage, the disposal methods of unused and expired medicines and their awareness and knowledge towards drug take back programme. Results: In this study 37.91 % out of the 807 participants had excellent knowledge on the rationale consumption and appropriate disposal of unused/expired medications, 48.94 % had average knowledge, but only 6.56 % of the total participants had more positive attitude and 66.66 % had positive attitude. Only around 45.84 % of the participants were following the good practices. Conclusion: Guidelines, policies and strict vigilant actions need to be initiated by government of India for safe utilisation of pharmaceutical products and disposal of unused/expired medications to safeguard our ecosystem from some of the major treats like antimicrobial resistance.

STRUCTURAL DESIGN OF A WORKBENCH FOR THE NEEDS OF A SERVICE TECHNICIAN

The presented paper deals with the structural design of a workbench with adjustable height, which will serve as part of the equipment of a light commercial vehicle for the needs of a service technician. The main objective of this paper is to create a functional design and 3D CAD model of a workbench that will meet the requirements of safety, mobility, and simple utilisation. Moreover, the design needs to consider the requirements of adjustable height and the dimensions of the work vehicle. The lifting mechanism is represented by arms fitted with sleeves that move along a lead trapezoidal screw rotating by a hand crank. In this paper, the force action in the axis of the threaded rod of the lifting mechanism is scrutinised in two extreme positions (highest and lowest position). The highest axial load on the threaded rod was found to be 9927.13 N in the lowest position of the mechanism. On the basis of this load, a right and left-hand trapezoidal threaded rod TR16×4 is selected, which satisfied the strength condition. The design of the sleeve height and the number of sleeve threads required are essential for safe utilisation. Due to the dimension of the guide rod, the height of the sleeve is selected to be 40 millimetres. The work surface is an important part of the workbench and consists of two parts. The chief larger part is made of medium density fibreboard and the smaller modular part can be in the two modular forms. The first version is the medium density fibreboard, and second alternative is a board designed to fix the components during their maintenance, repair as well as for welding.

Evaluation of Cd and Pb concentrations in soil-mulberry-silkworm system of a tailings pond, China

ABSTRACT The ecological reconstruction and safe utilisation of a large number of tailings ponds are very important. In this study, the accumulation and transportation of cadmium (Cd) and lead (Pb) in the soil-mulberry-silkworm system was evaluated through the mulberry planting and silkworm rearing at a tailings pond in Huayuan County, China. The results revealed that both the bioconcentration factors (BCFs) of mulberry for Cd and Pb were less than 1. The highest translocation factors (TFs) for both Cd and Pb were appeared in the stage from silkworm to excrement, followed by mulberry stem to leaf. The peak concentrations of Cd and Pb in the silkworm excrement were 2.33 mg kg−1 and 6.46 mg kg−1, respectively. Though the Cd and Pb contents in the cocoon shell from Yangjiazhai fitted the Technical Specifications of Ecological Textiles (GB/T 18885–2009, China), the ratio of cocoon shell was reduced by 17.06% under the stress of heavy metals. Developing the sericulture industry could be a reasonable way to utilise the tailings pond.

Normothermic Machine Perfusion as a Tool for Safe Transplantation of High-Risk Recipients

Normothermic machine perfusion (NMP) should no longer be considered a novel liver graft preservation strategy, but rather viewed as the standard of care for certain graft–recipient scenarios. The ability of NMP to improve the safe utilisation of liver grafts has been demonstrated in several publications, from numerous centres. This is partly mediated by its ability to limit the cold ischaemic time while also extending the total preservation period, facilitating the difficult logistics of a challenging transplant operation. Viability assessment of both the hepatocytes and cholangiocytes with NMP is much debated, with numerous different parameters and thresholds associated with a reduction in the incidence of primary non-function and biliary strictures. Maximising the utilisation of liver grafts is important as many patients require transplantation on an urgent basis, the waiting list is long, and significant morbidity and mortality is experienced by patients awaiting transplants. If applied in an appropriate manner, NMP has the ability to expand the pool of grafts available for even the sickest and most challenging of recipients. In addition, this is the group of patients that consume significant healthcare resources and, therefore, justify the additional expense of NMP. This review describes, with case examples, how NMP can be utilised to salvage suboptimal grafts, and our approach of transplanting them into high-risk recipients.

An attempt towards the safe utilisation of dangerous sediments deriving from mine water: a case study from the Polish part of the Upper Silesian Basin

An attempt towards the safe utilisation of dangerous sediments deriving from mine water: a case study from the Polish part of the Upper Silesian Basin

An attempt towards the safe utilisation of dangerous sediments deriving from mine water: a case study from the Polish part of the Upper Silesian Basin

An attempt towards the safe utilisation of dangerous sediments deriving from mine water: a case study from the Polish part of the Upper Silesian Basin

Role of Manual Therapy for Neck Pain and Quality of Life in Head and Neck Cancer Survivors: A Systematic Review.

Background:Pain is the one the most dreadful side effects of head and neck cancers and cancer related treatments affecting patients during and after the treatment adding to the problems affecting their ability to speak, swallow, breath and feeding. Manual therapy is standard set of physiotherapy treatments used for alleviating neck pain. It has found to be effective in small subset of cancer patients for relieving pain.Objectives:To highlight the use of various manual therapy techniques focusing in decreasing neck pain and improving quality of life in Head and Neck Cancer survivors that may suggest its safe utilisation in oncology rehabilitation.Materials and Methods:Electronic search was conducted in PubMed, Google Scholar, CINAHL, Pedro, and COCHRANE databases. Reference lists of the included studies and relevant reviews were manually searched. Studies that met the inclusion criteria were evaluated using McMaster critical review form for quantitative studies. A descriptive synthesis was undertaken due to the heterogeneity of the included studies.Results:Seven studies were assessed for risk of bias that comprised of three clinical trials, one case series and three case reports that applied Maitland’s mobilisation, Myofascial release, Muscle Energy Techniques to head and neck cancer survivors in various clinical settings. The outcomes highlighted decrease in pain, improvement in cervical range of motion and quality of life.Conclusion:This review recommends application of manual therapy to head and neck cancer survivors. However, authors caution application of manual therapy in terms of choosing a particular technique. Further, well designed larger sample size with randomisation and double blinding would help to generate better evidence for head and neck cancer survivors.

Hydromechanical rock mass characterization using discrete fracture network models – a case study based on terrestrial laser scanning and rock mechanical testing

Understanding the anisotropic hydraulic and mechanical properties of fractured rock masses is of great importance for a safe and optimal utilisation of the subsurface. Two sandstone quarries are utilized to obtain fracture network characteristics by Terrestrial Laser Scanning (TLS) producing 3d point cloud data. Semiautomatic analysis of the point clouds provides the probability density functions for each of the fracture parameters used as stochastic input for a Discrete Fracture Network (DFN) model. Rock mechanical laboratory tests are carried out to determine the mechanical properties of the intact rock and fractures. These parameters are then combined in the DFN model to calculate spatially variable tensors for permeability, Young’s modulus and Poisson’s ratio. Thereby, the spatial resolution of the tensor description is adapted to the grid size which can be used in further hydromechanical models. The approach allows to populate these models with more realistic parameters which incorporate also the effect of fractures on the rock mass behaviour. Obtained results are subsequently compared with conventional engineering rock mass classifications. The applied workflow allows for upscaling of rock properties determined in the laboratory to the anisotropic rock mass properties required for further hydromechanical modelling on larger scales, e.g., the reservoir scale.

Rice Physiological Response with Bacillus subtilis and Saccharomyces cerevisiae Inoculation into Soil under Reclaimed Water–Fresh Water Combined Irrigation

The increasing soil salinity levels under reclaimed water irrigation have a negative effect on plant growth. Greenhouse experiments were conducted in 2018 and 2019 under reclaimed water–fresh water combined irrigation. After transplanting (Day 1), rice was irrigated with clean water (tap water) for 10 days to facilitate rice root colonisation. Subsequently, rice was irrigated with reclaimed water for 50 days (Day 11 to 60), and then irrigated with clean water. B. subtilis and S. cerevisiae were mixed with clean water (tap water) and irrigated into soil at Day 61. B. subtilis (20 billion colony-forming units/g) and S. cerevisiae (20 billion colony-forming units/g) were mixed at the following proportions: 5 g and 0 (J1), 3.75 g and 1.25 g (J2), 2.5 g and 2.5 g (J3), 1.25 g and 3.75 g (J4), and 0 and 5 g (J5), respectively; rice treated with reclaimed water (CK) and clean water (J0) with no microorganisms applied were also used. We measured NO3--N and NH4+-N concentrations and electrical conductivity (EC) in the soil at 0–5, 5–15, and 15–25 cm layers; root activity; and malondialdehyde (MDA), soluble sugar, superoxide dismutase (SOD), peroxidase (POD), catalase (CAT), and glutamine synthetase (GS) activity in leaves at Day 71. B. subtilis and S. cerevisiae combination could promote rice physiological indices, and B. subtilis had a greater effect than S. cerevisiae. There are obvious differences in the physiological performance and soil N between 2018 and 2019 due to the EC of reclaimed water. Redundancy analysis revealed that soil NO3−-N and the mass of B. subtilis applied were major factors influencing leaf physiological indices. Five grams of B. subtilis is recommended to facilitate rice growth after irrigation with reclaimed water. Our research provides a new agronomic measure for the safe utilisation of reclaimed water.

Prediction of the Mechanical Performance of High-Strength Concrete Containing Biomedical Polymeric Waste Obtained from Dialysis Treatment

Since between 1.5 and 8 kg (400 kg/patient/year) of biomedical polymeric waste (BPW) is usually discarded by landfilling or combusting after each dialysis treatment, this study provides evidence for safe and environment-friendly utilisation of BPW, sourced from dialysis treatment and donated by the health and industrial partners, by incorporating it in high-strength concrete. Moreover, the paper aims to provide engineers, designers, and the construction industry with information regarding the mechanical performance of high-strength concrete containing BPW, and the susceptibility of the current international codes and standards on the prediction of the mechanical performance. A new concrete mix design incorporating BPW was proposed and verified by several trial mixes. Three Soft, Hard, and Hybrid BPW were added to the conventional high-strength concrete in different percentages ranging from 1.5% to 9% by weight of cement. Afterwards, the fresh and hardened concrete properties, namely slump, density, compressive strength, tensile strength, modulus of elasticity, and Scanning Electron Microscopy (SEM), were investigated, and existing prediction models were employed to verify their suitability for the new concrete. Generally, adding Hybrid BPW resulted in better mechanical performance than soft or hard BPW addition, while eliminating the waste separation phase. The results also showed that the mechanical performance of BPW-containing concrete is predictable by current codes, addressing possible engineering design limitations. New higher accuracy regression-based models were also proposed to reach better engineering interpretations.

Ankle fracture management using smartphone multimedia messaging service (MMS) imaging — How reliable and to what point?

BackgroundThe use of smartphones and multimedia messaging service (MMS) continues to increase in day to day orthopaedic clinical practice. However, there is limited evidence to support the safe utilisation of MMS. ObjectivesThe aim of this study was to correlate the performance of MMS imaging to picture archiving and communication systems (PACS) imaging within the setting of diagnosis and management of ankle fractures. MethodsThe ankle fracture radiograph series of 82 consecutive patients were evaluated by five orthopaedic consultant specialists. A questionnaire regarding diagnosis and preferred management was completed separately for each patient using smartphone and PACS images. Statistical analysis was performed using Intraclass Correlation Coefficient (ICC). ResultsAnkle fracture diagnosis showed strong to excellent correlation both inter- and intraobserver MMS vs PACS when using the Weber (0.815, 0.988), Anatomical (0.858, 0.988), and AO classification systems (0.855, 0.985). MMS was less reliable than PACS in determining many management options. ConclusionThe reliability of ankle fracture classification using MMS image viewing was not significantly different to interpretation on PACS workstations. Smartphone use in ankle fracture classification is supported by this study. Smartphone use was less accurate than PACS in devising management plans and future use should be limited to making only initial plans that must be corroberated with PACS and intraoperative findings prior to definitive fixation.

An online system for calculating and delivering long-term carrying capacity information for Queensland grazing properties. Part 1: background and development

This paper (Part 1) describes the development of a new online system that estimates long-term carrying capacity (LTCC) for grazing properties across Queensland, Australia. High year-to-year and multi-year rainfall variability is a dominating feature of the climate of Queensland’s grazing lands, and poses major challenges for extensive livestock production. The use of LTCC is one approach used by graziers to reduce the impact of rainfall variability on land condition and financial performance. Over the past 30 years, scientists, graziers and their advisors have developed a simple approach to calculating LTCC ((average annual pasture growth × safe pasture utilisation) ÷ annual animal intake). This approach has been successful at a property scale (regional south-west Queensland) and in a wider application through Grazing Land Management (GLM) regional workshops. We have built on these experiences to develop an online system (as described in detail in Part 2; Zhang et al. 2021; this issue) that incorporates the simple LTCC approach with advances in technology and grazing science to provide LTCC information for Queensland grazing properties. Features of the LTCC system are: (1) assimilation of spatial datasets (cadastral data, grazing land types, climate data, remotely-sensed woody vegetation cover); (2) a pasture growth simulation model; (3) land type parameter sets of biophysical attributes; and (4) estimates of safe pasture utilisation. The ‘FORAGE LTCC report’ is a major product of the system, describing individual property information that allows detailed analysis and explanation of the components of the LTCC calculation by land type and land condition. The online system rapidly analyses property spatial data and calculates paddock/property LTCC information. For the 10 months between November 2020 and August 2021, over 4000 grazing property reports have been requested in Queensland, and has proven to be a sound basis for ‘discussion support’ with grazier managers and their advisors.

An online system for calculating and delivering long-term carrying capacity information for Queensland grazing properties. Part 2: modelling and outputs

A combination of field data and models have been used to estimate long-term carrying capacity (LTCC) of domestic livestock in Queensland grazing lands. These methods have been synthesised and coupled with recent developments in science and information technology to provide a fully-automated approach of modelling LTCC through the FORAGE online system. In this study, the GRASP model was used to simulate pasture growth with parameter sets and safe pasture utilisation rates defined for 225 land types across Queensland. Distance to water points was used to assess the accessibility of pastures to livestock. Spatial analysis classified the property into unique areas based on paddock, land type and distance to water points, which estimated pasture growth, pasture utilisation and accessibility at a sub-paddock scale. Thirteen foliage projective cover (FPC) classes were used in modelling the pasture system to deal with the non-linear relationship between tree and grass interactions. As ‘proof of concept’, remotely-sensed individual-date green ground cover data were used to optimise the GRASP model parameters to improve the model performance, and a Monte Carlo analysis provided uncertainty estimates for model outcomes. The framework provides an efficient and standardised method for estimating LTCC. To test the system, LTCCs from 43 ‘benchmark’ properties were compared with simulated LTCCs, and 65% of the modelled LTCCs were within ± 25% of the benchmark LTCCs. Due to uncertainties in model inputs at the property scale and in model simulation, the modelled LTCC should be used as a starting point for further refinement of actual property LTCC.