Ruptured Corpus Luteum Research Articles

The Application Value of Ultrasound in the Diagnosis of Ovarian Torsion

In a study of 80 patients suspected of ovarian torsion and necrosis admitted to our hospital between January and December 2023, we analyzed the results of abdominal and vaginal ultrasounds with surgical diagnoses as the reference. Of the 80 cases, 74 were confirmed as ovarian torsion, accounting for 92.50%, while the remaining diagnoses included ruptured corpus luteum cysts, periapendiceal abscesses, and ruptured ectopic pregnancies, each with 2 cases. Abdominal ultrasound identified 63 cases of ovarian torsion and 17 cases of non-ovarian torsion, whereas vaginal ultrasound identified 73 cases of ovarian torsion and 7 cases of non-ovarian torsion. The sensitivity, specificity, and accuracy of abdominal ultrasound were 82.43%, 66.67%, and 78.75%, respectively, while those of vaginal ultrasound were 94.59%, 50.00%, and 91.25%. Although there was no statistical difference in specificity between the two methods (P > 0.05), vaginal ultrasound demonstrated significantly higher sensitivity and accuracy compared to abdominal ultrasound (P < 0.05). Thus, vaginal ultrasound is a more reliable diagnostic tool for ovarian torsion, providing valuable information for clinicians and improving diagnostic accuracy.

A rare bleeding disorder with severe haemorrhagic manifestation

Factor V is a major part of the coagulation system and maintains a balance in pro-coagulant and anticoagulant pathways. Any deficiency or mutation can lead to disequilibrium in coagulation. Factor V deficiency can be congenital or acquired. Congenital factor V deficiency (parahemophilia or Owren’s disease) is a rare autosomal recessive condition. We present a case of an adolescent unmarried girl presenting with an acute abdomen and deranged coagulation parameters. It was confirmed that the bilateral haemorrhagic ovarian cysts and hemoperitoneum were due to factor V deficiency. In her case, the bleeding was likely due to a ruptured corpus luteum during ovulation. She was successfully managed conservatively with red cells and fresh frozen plasma transfusions, tranexamic acid and combined oral contraceptive pills (COCP) with instructions to continue the use of COCP to prevent such bleeding manifestations.

Evaluation of The Effectiveness of Abdominal and Vaginal B-Ultrasound in The Diagnosis of Acute Abdomen in Obstetrics and Gynecology

Objective: To explore the clinical effect of the combined application of abdominal and vaginal B-ultrasound in the diagnosis of acute abdomen in obstetrics and gynecology. Methods: Eighty patients admitted to our hospital from March 2023 to March 2024 were selected, all of whom were acute abdomen patients admitted to the Department of Obstetrics and Gynecology. In this study, the patients were divided into two groups. One group of 40 patients was given a simple abdominal B-ultrasound diagnosis (control group). The other group of 40 patients was given both abdominal and vaginal B-ultrasound examinations (experimental group). The diagnostic accuracy between the two groups was compared. Results: Patients in the experimental group had higher consistency rates with pathological diagnosis results in ectopic pregnancy rupture, embryonic arrest, acute pelvic inflammation, corpus luteum rupture, and intrauterine adhesions as compared to the control group. At the same time, the inspection accuracy rate of the experimental group (92.50%) was higher than that of the control group (70.00%) (P < 0.05). Conclusion: The combined application of abdominal and vaginal B-ultrasound in the diagnosis of acute abdomen was of great significance in improving the accuracy of clinical diagnosis and guiding doctors to provide effective treatment.

Diagnosis and Management of a Ruptured Corpus Luteum Cyst: A Case Report from a Resource-Limited Setting

Diagnosis and Management of a Ruptured Corpus Luteum Cyst: A Case Report from a Resource-Limited Setting

EP31.10: The great mimicker: a complicated case of a ruptured corpus luteum

EP31.10: The great mimicker: a complicated case of a ruptured corpus luteum

Ruptured Corpus Luteum among Women Undergoing Laparotomy for Hemoperitoneum in a Tertiary Care Centre: A Descriptive Cross-sectional Study.

Rupture of the corpus luteum, though generally self-limiting in women with normal coagulation, could lead to life-threatening bleeding in patients with prosthetic valves on anticoagulant therapy and described in only a few case reports in the literature. The aim of this study was to find out the prevalence of ruptured corpus luteum among women undergoing laparotomy for hemoperitoneum in a tertiary care centre. This descriptive cross-sectional study was conducted among women undergoing laparotomy for hemoperitoneum in a tertiary centre from 7 April 2017 to 31 March 2021 after obtaining ethical approval from the Institutional Review Committee [Reference number: 328(6-11-E)2/73/74]. All women who underwent laparotomy for hemoperitoneum during the study period were enrolled. Convenience sampling technique was used. Point estimate and 95% Confidence Interval were calculated. Out of 447 women who underwent laparotomy for hemoperitoneum, ruptured corpus luteum was seen in 48 (10.74%) (7.87-13.61, 95% Confidence Interval). Out of which 36 (75%) had prosthetic valves. There was 1 (2.77%) mortality and 3 (8.33%) recurrences. The prevalence of rupture of the corpus luteum among women undergoing laparotomy for hemoperitoneum was similar to other studies done in similar settings. Early diagnosis, emergent reversal of coagulopathy and surgery if needed are the mainstay of management. anticoagulant; corpus luteum; hemoperitoneum.

Ruptured Corpus Luteum among Women Undergoing Laparotomy for Hemoperitoneum in a Tertiary Care Centre: A Descriptive Cross-sectional Study.

Rupture of the corpus luteum, though generally self-limiting in women with normal coagulation, could lead to life-threatening bleeding in patients with prosthetic valves on anticoagulant therapy and described in only a few case reports in the literature. The aim of this study was to find out the prevalence of ruptured corpus luteum among women undergoing laparotomy for hemoperitoneum in a tertiary care centre. This descriptive cross-sectional study was conducted among women undergoing laparotomy for hemoperitoneum in a tertiary centre from 7 April 2017 to 31 March 2021 after obtaining ethical approval from the Institutional Review Committee [Reference number: 328(6-11-E)2/73/74]. All women who underwent laparotomy for hemoperitoneum during the study period were enrolled. Convenience sampling technique was used. Point estimate and 95% Confidence Interval were calculated. Out of 447 women who underwent laparotomy for hemoperitoneum, ruptured corpus luteum was seen in 48 (10.74%) (7.87-13.61, 95% Confidence Interval). Out of which 36 (75%) had prosthetic valves. There was 1 (2.77%) mortality and 3 (8.33%) recurrences. The prevalence of rupture of the corpus luteum among women undergoing laparotomy for hemoperitoneum was similar to other studies done in similar settings. Early diagnosis, emergent reversal of coagulopathy and surgery if needed are the mainstay of management. anticoagulant; corpus luteum; hemoperitoneum.

Risk Prediction Model for Surgical Treatment of Ruptured Corpus Luteum in the Ovary

Risk Prediction Model for Surgical Treatment of Ruptured Corpus Luteum in the Ovary

Ruptured Corpus Luteum with Hemoperitoneum in Early Pregnancy

We present a 24-year-old woman with a positive β-human chorionic gonadotropin at 5 weeks and 4 days with acute postcoital lower abdominal pain. Imaging revealed acute intra-abdominal bleeding and no intrauterine or extrauterine fetal sac present. We considered both ruptured ectopic pregnancy and ovarian hemorrhage—recognizing that differentiation is difficult. At emergency laparoscopy (Fig. 1), the enlarged left ovary was actively bleeding, and luteal rupture with hemorrhage was diagnosed. Intraperitoneal lavage was performed, and hemostasis was achieved using bipolar coagulation and hemostatic agents (SURGICEL Powder Absorbable Hemostat; Ethicon Endo-Surgery, Cincinnati, OH).

A “Two-bal” Pregnancy: A Case Report on Heterotopic Pregnancy

Heterotopic pregnancy is defined as the combination of an intrauterine pregnancy and a concurrent pregnancy with an ectopic location, often the fallopian tube. Implantation can also occur in the cervix, ovary, cornua, abdomen, and previous Cesarean scar . While heterotopic pregnancy is considered a rare finding, the incidence is increasing due to the increased use of Assisted Reproductive Technology (ART). Heterotopic pregnancy is suspected when an ultrasound reveals an intrauterine pregnancy in addition to a complex adnexal mass. Differential diagnoses include: threatened abortion, ruptured corpus luteum cyst, and isolated ectopic pregnancy. Correct diagnosis can be difficult to attain due to nonspecific symptoms and findings such as: free fluid in the abdomen, abdominal pain, and vaginal bleeding. Patients are often diagnosed later than in an isolated tubal pregnancy due to these nonspecific symptoms and confirmation of an intrauterine pregnancy . Delayed diagnosis often leads to greater risk of rupture, an acute abdomen, and hemodynamic instability. Since the extrauterine pregnancy is non viable, salpingectomy is the surgical standard and first line treatment . However, other treatment modalities such as local feticidal injection have been performed depending on the clinical status of the patient and physician expertise. Finally, an ultrasound is to be performed after the procedure to confirm viability of the intrauterine pregnancy. During this case study, the patient presentation, diagnosis, and treatment of heterotopic pregnancy will be discussed in detail. The objective of this case study is to review the events and management of this unique patient presentation and discuss the recommended diagnosis and treatment options, as well as the incidence and prognosis of patients with this rare diagnosis.

Corpus luteum rupture mimicking acute appendicitis

Acute abdomen is a common presentation in women in the reproductive age. It may be caused by diverse conditions. The case below presented with classical signs and symptoms of appendicitis. Haemoperitoneum seen at laparotomy suggested a diagnosis of ectopic pregnancy .The diagnosis of ruptured corpus luteum cyst (RCLC) was made only after histology. The symptoms, signs and diagnosis of RCLC are discussed. The case highlights the need for circumspection in the diagnosis of the cause of acute abdomen. The current trend favours conservative management of RCLC thus the need for a high index of suspicion is emphasized to avoid unnecessary surgery.

A case report: ovarian apoplexy and ectopic pregnancy at once

Introduction: Ovarian Apoplexy is the sudden rupture of the ovarium that commonly occurs at the site of the corpus luteum cyst, followed by hemoperitoneum. Extremely uncommon but potentially fatal presentation, hemoperitoneum owing to cyst rupture has just a few cases documented in the literature. We report a woman 6 weeks delaying menstrual period, the pregnancy test was positive (second pregnancy). In this article, we aimed to report a rare case of ectopic pregnancy and ovarian apoplexy. Case Presentation: A 26 Years old woman with a history of abortion in her first pregnancy came to the emergency room with 3 days history of vaginal spotting and mild (2/10) continous right lower abdominal pain. She was suspected of incomplete abortion from primary health care. She was in 6 weeks delaying her menstrual period which is an uncommon case for incomplete abortion. The pregnancy test was positive (second pregnancy). Surgery was performed after completing the consent. Upon exploration of the abdomen, approximately 500 MLS of intraabdominal blood was identified. The right ovary's ruptured corpus luteum cyst was discovered to be the cause of the intra-abdominal bleeding. The hemorrhage was simply stopped by electrocauterization. Conclusion: Ovarian Apoplexy concomitantly occurs with an ectopic pregnancy and has not been reported before. Clinical signs and symptoms, especially pain perception of acute abdomen in a person with high pain tolerance, may bias the diagnosis.

Computed Tomography Characteristics of Ruptured Corpus Luteum:

Computed Tomography Characteristics of Ruptured Corpus Luteum:

Differential-diagnostic and therapeutic challenges in the management of ruptured corpus luteum cyst with undiagnosed intrauterine pregnancy in the early first trimester and ruptured ovarian pregnancy

Background: The similarities in clinical features between ruptured corpus luteum cyst (RCLC) with undiagnosed intrauterine pregnancy in the early first trimester (RCLC-P) and ruptured ovarian pregnancy are well established. However, the identification of differences between these two morbid conditions is important to determine the causes and manage the hemoperitoneum without devastation of pregnancy in RCLC-P. Furthermore, the pregnancy outcomes after laparoscopic surgery in women with RCLC-P are not recognized. Methods: Retrospective observational study of six women with RCLC-P and seven women with ruptured ovarian pregnancy. Results: All cases were referred under strong suspicion of ruptured ectopic pregnancy due to lower abdominal pain and positive urinary pregnancy test after spontaneous conception. The estimated median number of gestational weeks in RCLC-P (5 weeks) was significantly lower than that for ruptured ovarian pregnancy (7 weeks). At triage, the median serum levels of beta-human chorionic gonadotropin (β-hCG) were significantly lower in RCLC-P (592 IU/L) than ruptured ovarian pregnancy (3723 IU/L) (p = 0.01). In all six cases with RCLC-P, laparoscopic ovary-sparing surgery was performed. Among the four women who received postoperative supplementation of progesterone, uneventful vaginal delivery occurred at term in three cases. Conclusions: Early gestational age and lower serum β-hCG levels at triage, as well as non-declining levels of serum β-hCG on the day after surgery, were significant predictors of RCLC-P rather than ruptured ovarian pregnancy. Laparoscopic surgery was a feasible option for the management of RCLC-P with appropriate postoperative luteal support to achieve successful obstetric outcomes.

Clinical and Histopathological Findings of Ectopic Pregnancy Cases- A Retrospective Study from a Tertiary Care Hospital, Andhra Pradesh, India

Introduction: Ectopic Pregnancy (EP) is defined as a pregnancy that occurs in ectopic location, that is, outside the cavity of uterus. It is one of the leading causes of mortality in the first trimester of pregnancy and one of indication for emergency laparotomy. Timely diagnosis is extremely crucial as delay in diagnosis can lead to mortality. Diagnosing ectopic pregnancy is quiet challenging as there are many conditions which have similar presentation and may not require surgical management. Histopathology is required for confirmation of ectopic pregnancy by identifying trophoblastic tissue in ectopic location since there are other conditions like haematosalpinx, ruptured hemorrhagic corpus luteum which can have similar presentation clinically. Aim: To analyse the clinicopathological features of cases clinically diagnosed as ectopic pregnancy and estimate the percentage of cases which were confirmed on histopathology and assess the percentage of cases which were negative on histopathology. Materials and Methods: This was a retrospective observational study conducted on three years data collected retrospectively between July 2017 and June 2020. Clinical details like age of the patient, parity, gestational age, previous history of any associated risk factors for ectopic pregnancy, were obtained from patient requisition forms and pathology records. Hematoxylin and Eosin (H & E) stained sections were reviewed. Descriptive analysis was done. Data entry was made in Microsoft (MS) excel sheet. Frequencies and percentages were calculated. Results: Total of 128 cases (mean age 25.8±4.87 years) data was analysed in this study, most women were between 21 to 30 years (97 out of 128 (75.7%), with mean age of 25.8 years and presented in 2nd pregnancy (40 out of 86 cases where details were known (46.5%) and in 6th week of gestation (28 out of 78 cases where details were known) (35.8%)) with mean gestational age of 7.2 weeks. Most common risk factors were previous abortions and previous caesarean section (36 out of 82 cases where details were known (43.9% each)). Fallopian tube was the most common site (112 out of 113 cases, 99.1%). On histopathological examination, trophoblastic tissue was identified in 116 cases out of 128 cases. (90.6%). Twelve cases showed no evidence of trophoblastic tissues (11.7%), of these, three cases (25%) showed ruptured corpus luteum, seven cases (40%) showed hematosalpinx, and two cases (13.3%) showed chronic salpingitis changes. Conclusion: Ectopic pregnancy was most frequent in women between 21 to 30 years, in 2nd pregnancy and in 6th week of gestation. Most common risk factors were previous abortions and previous caesarean section. Fallopian tube was the most common site. Ectopic pregnancy was confirmed on histopathological examination, 90.6% cases. A total of 11.7% cases which showed no evidence of trophoblastic tissues, were cases of Haematosalpinx, ruptured hemorrhagic corpus luteum and chronic salpingitis and they presented clinically as ectopic pregnancy.

Abdominal emergency - Acute promyelocytic leukaemia presenting as a corpus luteal cyst

Acute promyelocytic leukaemia (APML) is known to present with disseminated intravascular coagulopathy (DIC) but as a Corpus luteal cyst hemorrhage however, it is rarely seen at presentation. This case is the first to describe a patient with APML who presented with ruptured corpus luteum without ovarian tissue infiltration with blasts, leading to hemoperitoneum posing as life threatening acute abdominal emergency in a woman belonging to child bearing age. The case is a singular case where APL has presented in such a rare manner.

Trends and outcomes of ruptured ovarian cysts

BackgroundRuptured ovarian cysts are common gynaecological presentation to health institutions with abdominal pain. While this phenomenon is generally self-limiting, surgery may be necessary in cases of haemodynamic compromise or association...

Successful Medical and Surgical Management of Massive Hemoperitoneum in Early Pregnancy

There are several cases reported in literature about management of adnexal masses and hemoperitoneum during pregnancy, however there is still no clear and standardized treatment. Through this manuscript we want to report our experience about the successfully treatment of massive hemoperitoneum due to corpus luteum rupture during first trimester of pregnancy.

A Probe into Application Value of Ultrasonography in Clinical Diagnosis of Gynecologic Acute Abdomen

This paper aims to observe and analyze application value of ultrasonography in clinical diagnosis of gynecologic acute abdomen. The 180 cases of gynecologic acute abdomen were selected as the subjects. All the cases were examined by ultrasonography. The results of ultrasonography were compared with those of clinical diagnosis and then application effect and practical value of ultrasonography were analyzed. Among the 180 patients, ultrasonography revealed 80 cases, 6 cases, 4 cases, 10 cases, 12 cases, 40 cases, 24 cases of ectopic pregnancy, corpus luteum rupture, ovarian tumor torsion, acute uterine perforation, acute pelvic inflammatory disease, placenta previa and miscarriage, respectively. 176 cases were detected by ultrasonography, with coincidence rate of 97.78 % compared to results of clinical examination. Ultrasonography is of great application value for gynecologic acute abdomen. During operation, ultrasonography is convenient and non-invasive, safe and reliable. It features high coincidence rate in examination, worthy of promotion in practice.https://sekabet.fun/https://asyabahis.fun/https://asyabahis.xyz/https://tipobet.fun/https://olabahis.fun/https://betist.fun/

Analysis of the Diagnosis and Treatment of Recurrent Rupture and Hemorrhage of Ovarian Corpus Luteum Cyst Induced by Imatinib

Objective: Rupture and hemorrhage of corpus luteum cyst is one of the common acute abdominal diseases in gynecology, which occurs in the middle and late menstrual cycle, and is often seen in women of childbearing age, often under the inducement of exercise and sexual life. There are few reports about drug-induced rupture and hemorrhage of corpus luteum cyst. Chronic myeloid leukemia (CML) is a common hematological disease and a chronic clonal myeloproliferative disease. Imatinib is a first-line drug for the treatment of chronic myeloid leukemia, and its efficacy and safety have been widely recognized, but there are still some adverse reactions. Among them, it is rare that the drug causes ovarian corpus luteum rupture and bleeding. In our clinical work, we just treated a patient with recurrent ovarian luteal cyst rupture and bleeding from imatinib, and followed up the whole course of the patient's pathogenesis, diagnosis and treatment effect. Therefore, this paper analyzes the clinical data and treatment of the case, in order to improve the clinical understanding and treatment of recurrent ovarian luteal cyst rupture and hemorrhage induced by imatinib. Methods: The clinical data and treatment of 1 case of recurrent ovarian corpus luteum cyst rupture bleeding from imatinib were analyzed, and the therapeutic effect was followed up. Results: Imatinib led to 6 times of corpus luteum rupture bleeding, which were successfully treated with conservative treatment. After taking Diane-35, the patient did not have corpus luteum rupture bleeding once again. And no adverse drug reactions. Conclusion: Imatinib can cause recurrent ovarian luteal cyst rupture and bleeding, conservative treatment is often effective. Diane-35 can effectively prevent and treat recurrent ovarian luteal cyst rupture and bleeding induced by imatinib. And the incidence of adverse drug reactions was low. But the specific mechanism that imatinib causes rupture of recurrent ovarian luteal cyst is unclear.