Background: The quality and duration of analgesia is improved when a local anesthetic is combined with alpha 2 adrenergic agonist. Though, the effects of clonidine on local anesthetics have been extensively studied, there are limited studies demonstrating the effects of epidural dexmedetomidine on local anesthetics. The aim of our study is to compare the effect of clonidine and dexmedetomidine when used as an adjuvant to ropivacaine for post operative analgesia after lower limb surgeries. Materials and Methods: Primary anesthetic technique in all the patients was spinal anesthesia. However femoral nerve block was placed at the completion of surgery by randomizing patients in two groups:Group C (20ml 0.25% Ropivacaine +1mcg/kg Clonidine) and Group D (20ml 0.25% Ropivacine +1mcg/kg Dexmedetomidine ) both containing 35 patients Onset of analgesia , duration of analgesia(It is time interval between administration of FNB & demand of rst resue analgesic ,total no of Rescue analgesics required in 24 hrs and quality of analgesia ,hemodynamic stability, post operative sedation scoring ,failure rate of technique and complications were recorded. Results: We found signicant difference in onset(9.41 ±0.73 mins) and duration(7.69±0.69 mins) of analgesia in group C as compared to onset(3.08 ±0.61 mins) and duration(11.16±0.58 mins) of analgesia in group D. No signicant complications were seen in either of the group.Conclusion: Dexmedetomidine at doses of 1 μg/kg is an effective adjuvant to ropivacaine for post operative analgesia after lower limb procedures .