Introduction: Treatment of root-treated teeth depends largely on proper restoration. Direct restorations are a better choice if there is sufficient residual tissue. This study aimed to investigate the knowledge of dental students in School of Dentistry in Yazd City about the taught factors of direct restoration of endodontically treated teeth.
 Methods: In this descriptive-cross-sectional study, the knowledge of 67 dental students of School of Dentistry in Yazd City about the taught factors of direct restoration of root-treated teeth was studied using a valid and reliable questionnaire containing demographic characteristics (age and gender) and 28 knowledge questions. After collecting the data, using SPSS version 16 software, they were analyzed using descriptive statistics, Chi-square test, Fisher's exact test, Mann-Whitney test, T test and Pearson correlation coefficient.
 Results: 36 (53.7%) female students and 31 (46.3%) male students with an average age of 25 ± 3.14 participated in this study. The average awareness score was 32.74 ± 9.65. The average knowledge score of female students (35.30±10.27) was higher than that of male students (31.95±8.70), but this difference was not statistically significant (p = 0.156). In the age group under 25, the average score of awareness (34.78 ± 9.94) was higher than the average above 25 (30.43 ± 8.1). There was an inverse and significant relationship between knowledge score and age, r=-0.242 and P 0.049. Conclusion: The average knowledge score of dental students regarding the taught factors of direct restoration of endodontically treated teeth was good. Gender did not have a significant effect on the knowledge of students, and the knowledge of students under 25 years old was higher than ones over 25 years old.