The aim of this paper is to investigate the patterns of importations of Levantine wines to Italy between the Early Empire and Late Antiquity. It concentrates on quantities of Levantine amphoras discovered in terrestrial contexts in Rome, Ostia, Campania and the North Adriatic part of Italy. This data is compared with published discoveries from other parts of Italy and the Roman Mediterranean, including finds from shipwrecks. Regression analyses is used in order to compare distribution patterns of Levantine amphoras in the Mediterranean (Rome, North Adriatic Italy, Spain, Gaul, Ephesus and Cyprus) during the Principate and Late Antiquity. The results of this study show that Levantine wines, and in particular Gazan varieties, became much more popular in the Later Roman and Early Byzantine periods than they had been during the first centuries of the Empire. Several explanations of this phenomenon are considered, including climate change and technological development in the Levant, as well as a structural transformation of the Roman economy.