A Discrete Element Method model, including interparticle cohesive forces, was calibrated and validated to develop a tool to predict the powder layer’s quality in the powder bed fusion process. An elastic contact model was used to describe cohesive interparticle interactions. The surface energy of the model particles was estimated by assuming that the pull-off force should provide the strength of the material evaluated at low consolidation with shear test experiments. The particle rolling friction was calibrated considering the bulk density of the layer produced by the spreading tool. The model was validated with the experiments by comparing the wavelet power spectra obtained with the simulations with those of the experimental layers illuminated by grazing light. The calibration proposed in this study demonstrated superior performance compared to our previous methods, which relied on measuring the angle of repose and unconfined yield strength.