Role Of MRI In Diagnosis Research Articles

Role of MRI in Diagnosis of Rapidly Progressive Cognitive Impairment- A Case Of Sporadic Creutzfeldt Jakob Disease (sCJD)

Abstract Background The role of neuroimaging in dementia extends beyond its traditional role of excluding neurosurgical lesions. Radiological findings may support the diagnosis of specific neurodegenerative disorders and aid differentiation from other neurodegenerative conditions e.g. CJD1. sCJD is a fatal neurodegenerative disease, which typically presents with neuropsychiatric symptoms, myoclonus, cerebellar and pyramidal/extrapyramidal symptoms. The diagnosis often is quite difficult, requiring high degree of suspicion, advanced neuroimaging and biochemical markers. Confirmation is only possible via brain biopsy. The condition can result in rapidly progressive dementia/neurocognitive decline and death, usually within a year from onset. Methods We report a case of a rapidly progressive dementia in a 79-year-old male who was diagnosed with probable sCJD, after having an MRI which picked up suspicious characteristic findings leading to the eventual diagnosis confirmation via further workup. The patient presented with acute rapid progressive forgetfulness and functional decline of 2 weeks with initial workup unyielding. Results A contrast MRI Brain eventually showed focal increased T2 and flair signals in the right parafalcine and parietal cortex demonstrating mild fluid restriction without any focal contrast enhancement, a pattern highly suspicious for sCJD. A CSF sample subsequently revealed RT-QulC positivity confirming the diagnosis. The patient eventually passed away despite ward-based care after 4 weeks of admission due to rapid neurological decline. A brain biopsy was not deemed feasible given patient’s condition. Conclusion The case highlights a relatively atypical symptomology of sCJD and, highlights the role of MRI imaging in assessment and diagnosis of dementias and specifically in sCJD. Increasing use of advanced neuroimaging may aid in diagnosis of specific/rare causes of rapidly progressive dementias. Reference Vitali, P., Maccagnano, E., Caverzasi, E., Henry, R.G., Haman, A., Torres-Chae, C., Johnson, D.Y., Miller, B.L. and Geschwind, M.D., 2011. Diffusion-weighted MRI hyperintensity patterns differentiate CJD from other rapid dementias. Neurology, 76(20), pp. 1711-1719.

Role of MRI in Patellofemoral Pain Syndrome (Anterior Knee Pain)

Abstract Background MRI is a good diagnostic tool in identifying cartilage and soft tissue lesions as well as detecting underlying predisposing anatomical factors of patellar instability, it has a high specification for detecting the grades and the types of some of these diseases or factors that may predispose to them such as trochlear dysplasia and patella alta. Aim of the Work The aim of this study was to evaluate the role of MRI in diagnosis of Patellofemoralpain syndrome which is the most common cause of anterior knee pain. Patients and Methods This prospective study was done on patients referred from the orthopedic clinic to the department of radiodiagnosis, MRI unit at Ain Shams University hospitals.Thirty patients were included (18 females and 12 males) and their age ranged from 20 to 64 years. Conclusion This study shows that MRI is useful in detecting various predisposing anatomical factors of patellofemoral instability and associated lesions of knee joint thereby enabling orthopedic surgeons to treat joint pathology as well as correct underlying anatomical abnormality.

Role of MRI in Early Detection of Non-Neoplastic Articular Causes of Hip Joint Disability in Adults

Background Painful hip is a common problem in the absence of a known acute trauma, it can be a diagnostic problem as it can be attributed to many causes. The most common causes are avascular necrosis, transient osteoporosis, osteoarthritis, FAI or inflammatory causes. Aim of the Work The aim of this study is to clarify the role of MRI in diagnosis of the etiology of hip pain in adults that causes hip joint disability and to compare between the accuracy of both conventional radiography and MRI in various abnormalities and conventional MRI and MR arthrography in FAI and labrum tear. Patients and Methods This study was conducted on 96 symptomatic patients (14 males and 16 females with age ranged from 18 to 68 years) diagnosed clinically with hip joint disability due to certain hip pathology at Orthopedic and Physiotherapy Departments and referred to Radiodiagnosis Department of Ain shams University Hospitals. Results After statistical analysis of the results depending on the final outcome of the cases, it was found that MRI is more sensitive and specific than conventional radiography in detection of different hip joint pathologies with MRI sensitivity, specificity, and total accuracy ranging from 80 to 100% and conventional radiography sensitivity and specificity and total accuracy ranging from 50 to 90 %. Conclusion MRI has become an essential imaging modality in musculoskeletal system in general and in hip region specifically. It is a non-invasive technique with no radiation hazards, informative and essential in painful hip.

Role of MRI in diagnosis of pulmonary embolism

BackgroundPulmonary embolism (PE) is considered a serious condition and has clinical challenges in diagnosis. Computed tomography pulmonary angiography (CTPA) is considered the gold standard in PE diagnosis. Contrast-enhanced MRA also has a strong useful role in the diagnosis. Our study aims to assess the role of non-contrast MRA in diagnosis of acute pulmonary embolism compared to either CT pulmonary angiography or contrast enhanced MRA.ResultsIn total, 50 patients with PE confirmed by either CTPA or CE-MRA were included in this study. All patients underwent non-contrast MRPA during the three consecutive days after CTPA or at the same examination setting in CE-MRA. The results were compared and statistically analyzed.The mean age of our study group was 47.80 ± 14.01 years. Males represented 56% (28/50) and females 44% (22/50). The per-vessel sensitivity, specificity and accuracy of non-contrast MRPA reached about 100% for each parameter at the level of the pulmonary trunk, main pulmonary and lobar arteries. At the segmental level, sensitivity, specificity, and accuracy reached about 88%, 100%, and 94%, while at the subsegmental level, about 35%, 100%, and 66% respectively. The overall sensitivity, specificity, and accuracy of non-contrast MRPA regardless of the site were 84%, 100%, and 90% respectively.ConclusionsNon-contrast pulmonary MRA has a high sensitivity and specificity in the diagnosis of PE, especially in proximal pulmonary arteries. So, it can be used as an alternative to the CTA and CE-MRA, especially when the CTA and the use of gadolinium are contraindicated.

The role of MRI in the prenatal diagnosis and classification of fetal microtia

ObjectiveTo investigate the role of MRI in the diagnosis and classification of fetal microtia.MethodsNinety-five fetuses with suspected microtia based on ultrasound and MRI performed within 1 week were enrolled in this study. The diagnosis based on MRI was compared with postnatal diagnosis. Among the microtia cases suspected on the basis of MRI, mild and severe cases were further classified. In addition, external auditory canal (EAC) atresia was evaluated by MRI in 29 fetuses with a gestational age > 28 weeks, and the accuracy of MRI in the diagnosis and classification of microtia was determined.ResultsOf 95 fetuses, 83 were considered to have microtia on the basis of MRI, 81 were confirmed to have microtia, and 14 were found to be normal according to postnatal diagnosis. Among 190 external ears in 95 fetuses, 40 ears were suspected to have mild microtia, and 52 ears were suspected to have severe microtia on the basis of MRI. According to the postnatal diagnosis, mild and severe microtia were confirmed in 43 and 49 ears, respectively. Among the 29 fetuses with a gestational age > 28 weeks, 23 ears were suspected to have EAC atresia according to MRI and 21 ears were ultimately confirmed to have EAC atresia. The accuracy of MRI in diagnosing microtia and EAC atresia was 93.68% and 93.10%, respectively.ConclusionMRI shows good performance in diagnosing fetal microtia and has the potential to evaluate its severity on the basis of classification and EAC status.Clinical relevance statementThis study was aimed at investigating the role of MRI in the diagnosis and classification of fetal microtia. MRI shows good performance and can help evaluate microtia severity and EAC atresia, thus allowing for better clinical management.Key Points• MRI is a useful adjunct to prenatal ultrasound.• MRI has a higher accuracy rate than ultrasound in diagnosing fetal microtia.• The accurate classification of fetal microtia and the diagnosis of external auditory canal atresia through MRI may help guide clinical management.

MRI Evaluation of Intradural Extramedullary Spinal Tumors with Histopathological Correlation - A Cross Sectional Study

Introduction: Tumors of nerve sheath, neurofibroma and schwannoma represent 30% of intradural extramedullary tumors. Schwannomas and neurofibromas are histologically composed of Schwann cells. Schwannomas almost always arise from the dorsal sensory roots and form well- encapsulated firm masses that compress adjacent tissue, without invading the involved nerve. Neurofibromas are more complex and are composed of Schwann cells mixed with fibroblast they involve the parent nerve. Meningiomas comprise approximately 25% of primary intraspinal tumors and are second only to nerve sheath tumors in frequency. Spinal cord meningiomas are originate from meningothelial cells near the distal root ganglia. Most menongiomas are intradural extramedullary, only 5% are extradural. Aim of the Study: The aim of this study was to evaluate the role of MRI in diagnosis of intradural extramedullary spinal tumors compared to histopathological findings. Methods: This was a cross sectional study and was conducted in the Department of Radiology and Imaging, Sylhet M.A.G. Osmani Medical College, Sylhet in collaboration with Department of Neurosurgery & Pathology of the same hospital, Sylhet, Bangladesh during the period from September, 2018 to August 2020. Result: In total 35 patients completed the study. In our study we found the Mean ± SD of age was 41.71±13.9 in years. Majority (54%) of our patients presented with spinal tumor were male compared to female (46%).We found schwannoma was diagnosed by (42.9%), meningioma (31.4%), neurofibroma (25.7%) respectively. Neurofibroma & schwannoma showed male predominance with 66.67% & 60% while meningioma showed female predominance with 63.6%. We found majority (55.6%, 60% & 72.7%) of neurofibroma, schwannoma & meningioma was in dorsal region respectively. Conclusion: In our study we found that MRI is a very sensitive and effective imaging procedure of suspected spinal schwannoma tumor of the spinal cord for accurate pre-operative diagnosis and ........

Role of MRI in the Diagnosis of Intra Medullary Spinal Tumor with Histopathological Correlation

Introduction: Intramedullary spinal cord tumor (IMSCT) constitutes 8% to 10% of all primary spinal tumors with the majority comprised of gliomas (80% to 90%), of which 60% to 70% are ependymomas and 30% to 40% are astrocytomas. Astrocytomas are common in the thoracic region whereas ependymomas are common in cervical region. Ependymomas are the most common glial tumor in adults, whereas astrocytomas are the most common intramedullary tumor in children. Overall, 15% of all primary intramedullary spinal cord tumors are ependymal in origin and include one of three histopathologic subtypes: ependymoma, subependymoma and myxopapillary ependymoma. Aim of the Study: The aim of this study was to evaluate the role of MRI in diagnosis of intra medullary spinal tumors compared to histopathological findings. Methods: This was a cross sectional study and was conducted in the Department of Radiology and Imaging, Sylhet M.A.G. Osmani Medical College, Sylhet in collaboration with Department of Neurosurgery & Pathology of the same hospital, Sylhet, Bangladesh during the period from September, 2018 to August 2020. Result: In total 35 patients completed the study. In our study we found the Mean ± SD of age was 41.71±13.9 in years. Majority (57%) of our patients presented with intramedullary spinal cord tumor were male compared to female (43%).We found that among of our 35 patients 20 (57.14%) were ependymoma, 15 (42.86%) patients were astrocytoma diagnosed by MRI. Majority (40%) patients of ependymoma belong to 41-50 years and majority patients of astrocytoma (40%) belong to 10-20 years old. Both ependymoma and astrocytoma showed male predominance with 55% and 60% respectively. It was observed that majority (70% & 55%) patients of ependymoma had back & radicular pain respectively. Majority (80% & 60%) patients of astrocytoma had back & radicular pain respectively. Ependymoma was determined by calculating sensitivity 95.0%, specificity 100%, accuracy 97.14%, PPV 100% and NPV 93.75% ....

"The Role of MRI for Diagnosis of Early-Stage Charcot Foot in Patients with Diabetes Mellitus Type 2"

Kamalov Telman Tulyaganovich1* and Tojiboev Salimgon Sobirovich2 Author Affiliations 1Head of the Diabetic Foot Department RSNPMTSE, Uzbekistan 2 Resident of the diabetic foot department of Republican Specialized Scientific and Practical Medical Center of Endocrinology of the Ministry of Health of the Republic of Uzbekistan named after acad. Y.H. Turakulova, Republic of Uzbekistan 2Physician of the diabetic foot Department of Republican Specialized Scientific and Practical Medical Center of Endocrinology of the Ministry of Health of the Republic of Uzbekistan named after acad. Y.H. Turakulova, Republic of Uzbekistan Received: June 10, 2022 | Published: June 23, 2022 Corresponding author: Kamalov Telman Tulyaganovich, Head of the Diabetic Foot Department RSNPMTSE, Uzbekistan 2 Resident of the diabetic foot department of Republican Specialized Scientific and Practical Medical Center of Endocrinology of the Ministry of Health of the Republic of Uzbekistan named after acad. Y.H. Turakulova, Republic of Uzbekistan DOI: 10.26717/BJSTR.2022.44.007098

Role of MRI in diagnosis of prostate cancer and correlation of results with transrectal ultrasound guided biopsy “TRUS”

BackgroundProstate cancer is the most common cancer in elderly men, and the second leading cause of cancer-related death in developed countries. For a long time, TRUS is used in screening, diagnosis of prostate lesions. Recently the implementation of multi parametric MRI into a screening program currently seems to be the most promising technique to improve the early detection of prostate cancer.ResultsThirty Patients were referred from urological outpatient clinics complaining of urological symptoms (dysuria, frequency and urine retention). The study was carried, and the patients were submitted to Ultrasonography, conventional magnetic resonance, diffusion weighted images and MR spectroscopy techniques, these results were correlated with histopathological data. In this study Conventional MRI has moderate sensitivity 81.8% and low specificity 37.3% in diagnosing prostate malignancy. Using of mpMRI combination of diffusion-weighted, Dynamic contrast enhanced and MR spectroscopic imaging is a promising approach for discriminating between benign and malignant lesions in the PZ and increase sensitivity 100% and specificity 96.6% in diagnosing prostate malignancy.ConclusionsThe standard for the definitive diagnosis of prostate cancer is trans-rectal ultrasound biopsy. However, TRUS guided biopsy has a significant sampling error and can miss up to 30% of cancers and may show underestimation of Gleason grade, especially in anteriorly located tumors. It may lead to an increase in complications. MRI has an essential role to play in making safer in diagnosis. It can aid in staging also and surgery or radiation treatment planning. Although T2W MRI has been used widely for diagnosis on the basis of its excellent soft tissue resolution, but its accuracy for the detection and localization of cancer prostate is unsatisfactory. The implementation of multi parametric MRI: MR spectroscopy, Dynamic contrast enhanced and diffusion weighted imaging into a diagnosis program improve the diagnostic performance. These advances are beginning to translate into better treatment selection and more accurate image-guided therapies. In addition, early detection of local recurrence.

The role of MRI in the diagnosis and management of tracheal diverticulum

BackgroundMultidetector CT is currently the best imaging method for detecting tracheal diverticulum (TD). Compared with CT, MRI is radiation-free and has higher resolution. However, the MRI characteristics of this disease have not been previously reported. The present retrospective study compared the MR and CT imaging features of TD, aiming to examine the role of MRI in TD diagnosis and management.MethodsImaging data were collected in 26 TD patients divided into two groups, including the uninfected and infected groups. The MR and CT imaging features (size/wall/channel) of uninfected patients were compared. The performances of MRI and CT in diagnosing and monitoring therapeutic efficacy in infected TD patients were comparatively assessed.ResultsThe uninfected group comprised 25 cases with 25 lesions confirmed by CT, including 23 lesions (92%) detected by MRI, with an average diameter of 8.5 mm (range from 3 to 15 mm). Meanwhile, the average diameter was 7.8 mm as measured by CT (range from 2.8 mm to 14.7 mm). The lesion diameters of the two cases not detected by MRI were 2.3 mm and 2 mm. MRI detected walls of all the 23 lesions (23/23), while CT detected no wall (0/23). CT showed channels in 18 lesions (18/23) versus3 for MRI (3/23). The infected case presented with a paratracheal abscess; MRI clearly showed a relationship between the abscess and the trachea, while CT could not show the lesion source. MRI also sensitively showed the whole process of lesion absorption.ConclusionsMRI can be used as a supplementary method for TD diagnosis, providing information about the wall that cannot be obtained by CT. MRI is superior to CT in diagnosing infected TD cases presenting with a paratracheal abscess, and in monitoring therapeutic efficacy in these patients.

Role of MRI in Diagnosis of Sacro-iliac Joint Lesions

Role of MRI in Diagnosis of Sacro-iliac Joint Lesions

Role of MRI in diagnosis of knee injuries in footballers

MRI findings are essential to diagnose the severity of ligament tears in knee injuries in footballers. By using Magnetic Imaging Resonance we can accurately make diagnose and can determine the extent of damage to tissues and ligaments by grading them according to injuries. Objective: The main objective of this study is to determine the MRI findings in patients of knee injuries in football players. MethodS: A multicenter descriptive study conducted at University of Lahore Teaching hospital and National hospital during 4 months period. All symptomatic football players of both genders and age ranging from 16-40 year are included in this study. Our calculated sample size is 80. 1.5T MRI machine used for scans. All images were Proton density and T2 weighted images. Results: This study includes 80 footballers complaining knee pain. Mean age of all subjects was 31.4 +, - 5.7 year. Among 80 patients who had knee injuries, 56 patients (70%) had ACL injuries, 14 patients (17.5%) had PCL injuries, 14 patients (17.5%) had LCL injuries, 8 patients (10%) had MCL injuries, 24 patients (30%) had LM injuries, and 31 patients (38.8%) had MM injuries. Conclusion: MRI is useful imaging modality for the detection of soft tissue injuries most commonly sports injuries. It gives more accurate and detailed information of ligaments and muscle tears than any other modalities. In our study most common injuries that are detected by MRI are ACL tear, bucket handle tear of medial meniscus and MCL injuries. PCL injuries are less common than ACL injuries.

The Role of MRI in Diagnosis and Management of Breast Cancer during Fertility Period

The Role of MRI in Diagnosis and Management of Breast Cancer during Fertility Period

Role of magnetic resonance imaging in diagnosis and grading of perianal fistulas

Background: Fistula-in-ano can be defined as a hollow tract or cavity which is lined by granulation tissue. In case of fistula-in-ano, one end of this fistula opens in the anal canal whereas the other end is located in perianal area. Fistula-in-ano can considerably affect quality of life of an individual because of perianal discharge of blood and pus. Imaging of these fistulas is an important part of management and MR imaging is important in assessing relationship between the fistulous tract and sphincter muscles. Moreover, MR imaging can reliably demonstrate transmural inflammation, secondary tracts/ramifications, and abscesses which cannot be diagnosed on the basis of conventional fistulography. Aims and Objectives: The aim of the study was to evaluate role of MRI in diagnosis and grading of perianal fistulae. Materials and Methods: This was a retrospective observational study, in which 60 patients with fistula-in-ano were included on the basis of a predefined inclusion and exclusion criteria. MR imaging of patients was done by 1.5 T MRI machine. Before MR imaging normal saline was injected in the fistulous tract from secondary/external opening, that is, opening around perianal area. Three plane images were obtained in all the cases. T1W, T2W, and STIR image sequences were obtained parallel to pelvic diaphragm. Coronal cuts were imaged parallel to anal canal. FAT suppressed T1W and T2W images in all cases. Type and grade of fistula were determined in all the cases. P < 0.05 was taken as statistically significant. Results: Out of total 60 patients, there were 46 (76.66%) males and 14 (23.33%) were females with a M:F ratio of 1:0.30. The mean age of male and female patients was found to be 41.93±8.96 years and 44.04±7.46 years, respectively. The most common type of fistula was found to be trans-sphincteric fistula which was seen in 31 (51.6%) cases followed by intersphencteric fistula 22 (36.6%). Extrasphincteric and suprasphincteric fistulae were relatively uncommon and were seen in 4 (6.66%) and 3 (5%) cases, respectively. MRI was accurate in diagnosis of the tract with position of internal opening and any abscess cavity or secondary tract in 23 patients. Therefore, the diagnostic accuracy of MRI was found to be 95.4%. Conclusion: MRI is an excellent tool in assessment of perianal fistula. It not only helps in precisely locating fistulous tract but also can demonstrate relationship between the fistulous tract and sphincter muscles. Moreover, it can very well demonstrate transmural inflammation, secondary tracts/ramifications, and abscesses which cannot be assessed by conventional fistulograms.

222P Inflammatory breast cancer: What information we can expect from MRI and how to use it

Inflammatory breast cancer (IBC) is an aggressive breast malignancy with rapid onset and poor outcomes. Correct diagnosis and efficient treatment in the form of neoadjuvant chemotherapy (NAC) improve these patients' prognosis. However, the biopsy is often falsely negative, and the effect of NAC is rarely predictable. This study is aimed at the role of MRI in diagnosis, staging (lymph nodes LN) and NAC response prediction of IBC.

Role of contrast-enhanced FLAIR MRI in diagnosis of intracranial lesions

BackgroundMR imaging plays a significant role in detection and characterization of different brain diseases. The role of the post-contrast T1-weighted image magnetic resonance imaging (T1W MRI) sequence has been widely established in previous studies and clinical practice. In this study, we aim to share our experience as regards the added value of contrast-enhanced fluid-attenuated inversion recovery (CE-FLAIR) sequence in the diagnosis of various intracranial pathological conditions and evaluate its usefulness in comparison with post-contrast T1W images.ResultsBased on the final radiological diagnosis, the total cases were subdivided into three categories, and the majority of our cases were tumors (81.2%), followed by multiple sclerosis (11.8%), and the least was central nervous system infection (7.1%). CE-FLAIR showed superior enhancement in 35 cases (50.7) and equal enhancement in 25 cases (36.3%). However, it showed less enhancement than post-contrast T1W images in 9 cases (13%). Excellent inter-observer agreement (97.65%) was noted. Regarding lesion conspicuity, good delineation was found in the majority of cases (64.7%), fair delineation in 12.9%, and no delineation in 22.4%. A statistically significant difference was found in signal intensity of lesion between pre- and post-contrast FLAIR sequences. Contrast to background ratio was statistically significant in CE FLAIR images in comparison to CE T1 images.ConclusionCE-FLAIR imaging should be used as a routine or adjunctive sequence to CE-T1WI to enhance early detection and increase the diagnostic confidence in MRI examination of different brain pathological conditions.

ROLE OF MAGNETIC RESONANCE IMAGING IN DIAGNOSIS OF IDIOPATHIC INTRACRANIAL HYPERTENSION

Idiopathic intracranial hypertension (IIH) is a disorder of unknown cause that results in increased intracranial pressure without localizing neurologic findings .Brain imaging using MRI is important to exclude any mass occupying lesion or dural sinus thrombosis.MRI features of IIH include elevation of the optic nerve head, empty sellaturcica ,distention of the peri-optic subarachnoid space, tortuosity of the optic nerves, flattening of the posterior sclera of the globe, and dural venous sinus stenosis.AIM OF THE WORK:This study was conducted to study the role of MRI in diagnosis of benign intracranial hypertension.PATIENTS AND METHODSPATIENTS:This study was carried out on 20 patients with symptoms of intracranial hypertension referred to the Radio-diagnosis Department, Main University Hospital, Alexandria University from November 2019 to November 2020.METHODS:The studied patients were subjected to the following:Detailed history taking and thorough clinical examination.Imaging evaluation of the brain including :Routine magnetic resonance imaging sequences including 3D T1, axial, sagittal and coronal T2, axial FLAIR.T1 Weighted post contrast axial images if needed.MRV if needed to visualize dural venous stenosis or thrombosis

Magnetic Resonance Imaging Role in Evaluation and characterization of Hand and Finger Lesions

Background: MRI describes the main features of the encountered different pathological lesions of the hand and fingers, as well as specifies the signal characteristics and location, which help to differentiate them. In general, a specific diagnosis may be achieved by taking into account the location of the lesion within the hand or wrist and its signal characteristics. Aim: The aim of the study is to evaluate the role of MRI in diagnosis of various hand and finger pathologies using different sequences. Methods This is a prospective observational study of patients who suffers from hand or fingers swelling or trauma. The patients were investigated by MRI. Results: The study included 30 patients with hand or finger lesions who were evaluated by MRI and enrolled from Benha University hospitals. Conclusion: Magnetic resonance imaging is the preferable method of choice for evaluating various hand and finger lesions in traumatic and non-traumatic condition if conventional radiography isn’t enough

Atypical Presentation of Cervical Pott’s Disease: A Case Report

Tuberculous spondylitis, also known as Pott’s disease, is due to infection of the spine by mycobacterium tuberculosis (MTB) leading to vertebral body and inter-vertebral disc destruction. It is the most common form of musculoskeletal tuberculosis most frequently affecting the thoracolumbar spine and is commoner in young people. Onset of this condition is insidious and its clinical presentation is non specific. However, Pott’s disease may be complicated by neurologic deficits including paraplegia or even quadriplegia, with huge health, economic and psychological burden. Following is a case report of Pott’s disease involving the cervical spine in a 33-year old farmer presenting unusually with paraplegia and a negative Mantoux test. It is reported because this very uncommon condition is highly treatable, and there is need for a raised index of suspicion in order to diagnose this condition early, thus limiting its complications. The role of MRI in diagnosis of Pott’s disease is also highlighted.

An Overview on the Role of MRI in Diagnosis and Management of Berry Aneurysm

Berry aneurysms are also known as saccular aneurysms are pathological dilatations of intracerebral arteries, that are typically located within the anterior circulation of the brain. the exact etiology of their formation is still enigmatic, but it’s postulated to be multifactual, through an interplay between familiar disposition, environmental factors, and degenerative processes. They are approximately found in around 3% of the general population. But the majority of cases are asymptomatic