Human growth and development can be seen from fine and gross motor skills, cognitive abilities, and the maturity of cells in the body. A person's growth and development will reach the peak phase. People have differences regarding the factors of decline (degeneration) they experience. The process of decline can increase a person's risk of developing various diseases. Hypertension cases make this disease a contributor to the highest risk of death. Hypertension cases caused by lifestyle can be prevented or treated by exercising as a protector and treating hypertension cases. Hypertension cases caused by lifestyle can be prevented or treated by exercising as a protector and treating hypertension cases. This research method used a literature review search from 2018 to 2023 resulting in 556 articles which were selected into 5 articles according to research criteria. Research results of physical activity for 150 minutes/week with moderate intensity or 75 minutes/week with high intensity to improve the quality of fitness and public health. Combining aerobic exercise with weight training at least 2 times/week, with regular physical activity will increase a person's life expectancy, especially in the prevention and treatment of hypertension.