With the continuous deepening of globalization and informatization, the construction of smart cities is gradually becoming a core strategy in the process of urban modernization. In this strategy, Geographic Information Systems (GIS) play a crucial technical support role. This article adopts a case study method, taking the construction of a smart city in Nanjing as the specific research object, and deeply explores the practical application of GIS in key fields such as urban planning, environmental protection, and traffic management. Through comprehensive analysis of these examples, this article systematically summarizes the significant achievements of GIS technology in improving urban management efficiency, optimizing decision support systems, enhancing public service levels, and promoting sustainable urban development. The research results indicate that GIS technology provides solid data support and decision-making support for the core areas of cities through precise integration and analysis of geographic information. GIS technology not only optimizes the layout of urban infrastructure, but also significantly enhances the city's response to emergency events through real-time monitoring and dynamic simulation, while promoting efficient allocation and utilization of urban resources. The research conclusion points out that, GIS technology is the cornerstone of smart city construction, greatly enhancing the scientific and forward-looking nature of urban management. The effective application of GIS has opened up new avenues for intelligent and refined urban management, significantly improving the quality of life of residents and providing solid technical support for the sustainable development of cities.
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