Robust Carrier Research Articles

Tunable Ultrafast Charge Transfer across Homojunction Interface.

Charge transfer at heterojunction interfaces is a fundamental process that plays a crucial role in modern electronic and photonic devices. The essence of such charge transfer lies in the band offset, making charge transfer uncommon in a homojunction. Recently, sliding ferroelectricity has been proposed and confirmed in two-dimensional van der Waals stacked materials such as bilayer boron nitride. During the sliding of these layers, the band alignment shifts, creating conditions for charge separation at the interface. We employ ab initio nonadiabatic molecular dynamics simulations to elucidate the excited state carrier dynamics in bilayer boron pnictides. We propose that, akin to ferroelectric polarization flipping, the precise modulation of the distribution of excited state carriers can also be reached by sliding. Our results demonstrate that sliding induces a reversal of the frontier orbital distribution on the upper and lower layers, facilitating a robust interlayer carrier transfer. Notably, the interlayer carrier transfer is more pronounced in boron phosphide than in boron nitride, attributed to strong electron scattering in momentum space in boron nitride. We propose this novel method to manipulate carrier distribution and dynamics in a homojunction exhibiting sliding ferroelectricity, in general, paving a new way for developing advanced electronic and photonic devices.

A robust and continuous carrier phase prediction strategy for GNSS/INS deeply coupled systems

A robust and continuous carrier phase prediction strategy for GNSS/INS deeply coupled systems

Accelerating Anhydrous Proton Transport in Covalent Organic Frameworks: Pore Chemistry and its Impacts

AbstractProton conduction is important in both fundamental research and technological development. Here we report designed synthesis of crystalline porous covalent organic frameworks as a new platform for high‐rate anhydrous proton conduction. By developing nanochannels with different topologies as proton pathways and loading neat phosphoric acid to construct robust proton carrier networks in the pores, we found that pore topology is crucial for proton conduction. Its effect on increasing proton conductivity is in an exponential mode other than linear fashion, endowing the materials with exceptional proton conductivities exceeding 10−2 S cm−1 over a broad range of temperature and a low activation energy barrier down to 0.24 eV. Remarkably, the pore size controls conduction mechanism, where mesopores promote proton conduction via a fast‐hopping mechanism, while micropores follow a sluggish vehicle process. Notably, decreasing phosphoric acid loading content drastically reduces proton conductivity and greatly increases activation energy barrier, emphasizing the pivotal role of well‐developed proton carrier network in proton transport. These findings and insights unveil a new general and transformative guidance for designing porous framework materials and systems for high‐rate ion conduction, energy storage, and energy conversion.

Accelerating Anhydrous Proton Transport in Covalent Organic Frameworks: Pore Chemistry and its Impacts.

Proton conduction is important in both fundamental research and technological development. Here we report designed synthesis of crystalline porous covalent organic frameworks as a new platform for high-rate anhydrous proton conduction. By developing nanochannels with different topologies as proton pathways and loading neat phosphoric acid to construct robust proton carrier networks in the pores, we found that pore topology is crucial for proton conduction. Its effect on increasing proton conductivity is in an exponential mode other than linear fashion, endowing the materials with exceptional proton conductivities exceeding 10-2 S cm-1 over a broad range of temperature and a low activation energy barrier down to 0.24 eV. Remarkably, the pore size controls conduction mechanism, where mesopores promote proton conduction via a fast-hopping mechanism, while micropores follow a sluggish vehicle process. Notably, decreasing phosphoric acid loading content drastically reduces proton conductivity and greatly increases activation energy barrier, emphasizing the pivotal role of well-developed proton carrier network in proton transport. These findings and insights unveil a new general and transformative guidance for designing porous framework materials and systems for high-rate ion conduction, energy storage, and energy conversion.

Immobilization of Xylanase on ZnO nanoparticles obtained by green synthesis from Eupatorium cannabinum L. and its application in enrichment of fruit juices

Juice production is one of the main components of the nutritional food industry. Therefore, improving fruit juice quality and preventing the formation of negative by-products is important for human health. The role of environmentally friendly, safe and economically more affordable green nanocarriers in improving the quality of fruit juice is increasing day by day. For this purpose, zinc oxide nanoparticles (ZnONPs) were prepared from the aqueous extract of the Eupatorium cannabinum L. using the green synthesis method. After immobilization, structural and morphological characterizations of the prepared ZnONPs and xylanase (Xyl)@ZnONPs were carried out, which confirmed that both the synthesis of ZnONPs and the immobilization of Xyl enzyme on ZnONPs were successfully carried out. The biochemical parameters of Xyl@ZnONPs such as optimum pH and temperature, kinetic parameters, thermal stability, reusability, and storage stability were investigated and compared with free Xyl. After immobilization, the optimum pH of free Xyl shifted from 5.0 to an alkaline pH of 8.0, while no change in the optimum temperature (70 °C) was observed for both enzymes. While the activation energy of free Xyl was 5.56 kJ/mol, it was found to be 7.27 kJ/mol for Xyl@ZnONPs. Xyl@ZnONPs outperformed free Xyl due to its long-term storage stability and reusability. Moreover, Xyl@ZnONPs retained 50 % of its activity after 5 reuses and 87 % of its activity after 4 weeks of storage at room temperature. In addition, a decrease in Km value and an increase in Vmax value were observed after immobilization, which means the increased catalytic activity of the Xyl@ZnONPs. As a result of re-using Xyl@ZnONPs in orange juice for 6 cycles, clarification yield of 66.43 % was obtained under optimized conditions. Overall, this study prepared a suitable, environmentally friendly, and robust carrier support for Xyl immobilization and developed a biocatalyst that will provide high performance in the industrial field.

Robust Pseudorange and Carrier Phase Multipath Mitigation With Hemispherical Map Considering the Uncertainty

Robust Pseudorange and Carrier Phase Multipath Mitigation With Hemispherical Map Considering the Uncertainty

Femtosecond Laser Cutting of Human Crystalline Lens Capsule and Decellularization for Corneal Endothelial Bioengineering.

The bioengineering of corneal endothelial grafts consists of seeding in vitro cultured corneal endothelial cells onto a thin, transparent, biocompatible, and sufficiently robust carrier which can withstand surgical manipulations. This is one of the most realistic alternatives to donor corneas, which are in chronic global shortage. The anterior capsule of the crystalline lens has already been identified as one of the best possible carriers, but its challenging manual preparation has limited its use. In this study, we describe a femtosecond laser cutting process of the anterior capsule of whole lenses in order to obtain capsule discs of 8 mm diameter, similar to conventional endothelial grafts. Circular marks made on the periphery of the disc indicate its orientation. Immersion in water for 3 days is sufficient to completely remove the lens epithelial cells and to enable the seeding of corneal endothelial cells, which remain viable after 27 days of culture. Therefore, this method provides a transparent, decellularized disc ready to form viable tissue engineered endothelial grafts.

Development and Characterization of Modified Chitosan Lipopolyplex for an Effective siRNA Delivery.

Cytotoxicity, speedy degradation, and limited cellular absorption are the foremost features influencing the successful delivery of RNAs. Chitosan (Cs) is a polymer that offers an advantage due to its bio-compatibility and biodegradable nature, making it an ideal polycationic vector for delivering siRNA. In this study, chitosan has been modified with arginine in order to increase its encapsulation of siRNA and improve cellular absorption. It was discovered that arginine and guanidino moieties could transport through membranes of cells and play an important part in membrane permeability. FTIR and 13C NMR were used to characterize the complex. These chitosan-arginine (CsAr) siRNA complexes are further encapsulated in anionic DPPC/cholesterol liposomes to combine the effects of liposome-chitosan-arginine complexes called lipopolyplexes (LCAr). Formed LCAr were investigated for their lipid/CsAr-siRNA ratios, size, zeta-potential, heparin, and serum RNase stability by agarose gel retardation, and cell uptake efficiency compared to their "parent" polyplexes. Results revealed complete lipidation of CsAr-siRNA polyplexes at lipid mass ratio 10 resulting in lipopolyplexes in the 120 to 230nm range. Polyplex entrapped ~70% of siRNA, whereas lipidation increases siRNA encapsulationto ~95%. Developed LCAr showed ~4 times less hemolytic potential as compared to the parent polyplexes at the highest siRNA dose. The CsAr-siRNA and its lipid-coated form showed enhanced cellular association as compared to the marketed Lipofectamine 2000 proving its effectiveness in siRNA delivery. CsAr-liposome conjugation is simple and safe, and serves as a robust carrier for gene transport in physiological situations without compromising transfection efficacy.

Abstract 377: Developing a Novel Oxygen Carrier for Resuscitation and Oxygen Delivery Through Targeted Mutations of Recombinant Heme-Proteins

Introduction: Hemorrhage is a leading cause of death in trauma patients. Interventions dedicated to hemostatic resuscitation have demonstrated benefit in decreasing mortality due to hemorrhagic injury. There remain significant limitations to donor-based blood transfusions. We have identified a heme-binding protein, the Bacterial Regulator of carbon monoxide metabolism (RcoM), with suitable properties to be a robust artificial oxygen carrier. We have engineered a variant that lacks a DNA binding domain and contains cysteine mutations for improved stability (RcoM HBD-CCC). Hypothesis: We hypothesize that engineered RcoM HBD-CCC can be used as an ideal artificial oxygen carrier due to the optimization of 4 factors: ligand binding, nitrite reduction rate, autoxidation rate, and thermal denaturation. Methods: Spectrophotometric methods were used to characterize RcoM HBD-CCC in terms of its biochemical properties for optimal oxygen transport and release. Specifically, ligand binding was tested by determination of the P50 (oxygen pressure for 50% saturation of the molecule) value indicating the affinity of RcoM HBD-CCC towards oxygen. Nitrite reduction assays were carried out to test the rate at which nitric oxide (NO) forms to counteract potential NO scavenging. The autoxidation rate determines how long a protein stays in the reduced state, where it is able to bind to oxygen. Thermal denaturation (T m ) identifies the resistance of a protein to higher temperatures. Results: We determined that RcoM HBD-CCC’s P50 value was 4.2 mmHg which is within the ideal range for oxygen binding affinity given that optimal values for oxygen carriers to mimic hemoglobin oxygen dissociation are between 1 to 26 mmHg. Nitrite reductase rate was 5.6M -1 s -1 which is well above the rate for Hb (K = 0.12 M -1 s -1 ). RcoM HBD-CCC has a low autoxidation rate at 0.016 min -1 . RcoM HBD-CCC has a T m of 71°C which is well above all ambient environmental temperatures. Conclusion: We have designed and synthesized a variant of RcoM that we have demonstrated in in vitro spectrophotometric assays to have ideal biochemical properties for an artificial oxygen carrier. We next plan to test the efficacy of RcoM HBD-CCC in animal models of hemorrhage and assess safety in animal exposure models.

Robust packet loss compensation in the cloud‐based TT&C receiver using a predictive tracking loop with RBF network identification

AbstractIn recent years, ground‐based aerospace tracking, telemetry and control (TT&C) systems have been shifting towards an IP‐based cloud TT&C network architecture to improve signal transmission efficiency and system flexibility. However, this new architecture presents new challenges for the performance of tracking loops in the cloud‐based TT&C receiver. The authors present a predictive compensation tracking loop that addresses the problem of packet loss. The loop utilises radial basis function (RBF) online network identification for robust carrier and code frequency offset tracking. To account for packet loss, the phenomenon is modelled as a Bernoulli random process, and the predictive compensation loop uses the trained RBF network to maintain the system's tracking state. When normal data are received again, the loop can track the received information well and align the frequency offset locking state. The authors compare the performance of the proposed predictive compensation tracking loop with traditional loop tracking performance using data hold strategies under different packet loss rates. The results demonstrate the effectiveness of the proposed approach in maintaining stable tracking and solving in the discontinuous reception of the loop under packet loss environments. The proposed predictive compensation tracking loop offers a practical solution for addressing packet loss, which is a common issue in real‐world applications.

Biomimetic Metal-Pyrimidine Nanoflowers: Enzyme Immobilization Platforms with Boosted Activity.

For the enzyme immobilization platform, enhancing enzyme activity retention while improving enzyme stability remains a challenge for sensitive sensing analysis. Herein, an in situ biomimetic immobilized enzyme carrier (metal-pyrimidine nanoflowers, MPNFs) synthesized by the coordination of DNA base derivative (2-aminopyrimidine) with Zn2+ in the aqueous phase at room temperature is developed. The biocompatibility of 2-aminopyrimidine and the hydrophilicity and green synthetic conditions of MPNFs allows the immobilized enzymes to retain above 91.2% catalytic activity. On this basis, a cascade catalytic platform is constructed by simultaneously immobilizing acetylcholinesterase (AChE), choline oxidase (CHO), and horseradish peroxidase (HRP) in MPNFs (AChE/CHO/HRP@MPNFs) for organophosphorus pesticides (OPs) colorimetric biosensing detection. The assay could specifically detect parathion-methyl within 13min with a wider linear range (0.1-1000.0nm) and a lower limit of detection (LOD) (0.032nm). The remarkable stability of the immobilized enzymes is also achieved under harsh environments, room temperature storage, and recycling. Furthermore, a portable and cost-effective biosensing platform is developed by integrating AChE/CHO/HRP@MPNFs with a smartphone-assisted paper device for the on-site detection of OPs. Overall, the high catalytic activity retention and the enhanced detection performance demonstrate that MPNF is a robust carrier in enzyme immobilization and holds great promise in biosensing and other field applications.

Galactose-functionalized injectable thermosensitive microgels for target specific uptake in hepatoma cells.

Microgels acts as a potential candidate for responsive composite materials, which has been favored by scientists because of its excellent colloid stability, easy integration, and most of their surface area can be used as support after modification. Specififically, microgels are fascinating capable of maintaining good biocompatibility and controlled-release in vivo and making the possible for applications in biomaterials and biomedicines. Besides, in the process of microgel synthesis, some targeting factors can be combined to achieve the purpose of cell targeting and uptake. Therefore, how to fundamentally design microgels is an urgent problem to be solved. In this study, we design and synthesize an injectable microgel P(DEGMA-co-OVNGal) that is made of 2-methyl-2-acrylate-2-(2-methoxy ethoxy) ethyl ester (DEGMA) and glycopolymer (OVNGal) that is thermoresponsive and contains galactose. When the content of crosslinking agent is regulated, the microgel will realize the transformation from sol to gel at the temperature around human body, causing the controlled release of the loaded drugs. With the increase of crosslinker content from 1% to 7%, the appearance of microgel changed from loose and ordered to compact and hard morphology, the swelling ratio of microgel decreased from 187% to 142%, and the phase volume transition temperature decreased from 29.2°C to 28°C. The results indicated that when the monomer ratio (DEGMA: OVNGal) increased from 2:1 to 40:1 with the amount of crosslinking agent at 1%, the particle size of microgel increased from 460nm to 660nm. In vitro released studies confirmed that the cumulative released DOX (doxorubicin, as a selected model drug) from the microgel can reach 50% after 7days. Furthermore, in vitro experiments demonstrated that the injectable microgel P(DEGMA-co-OVNGal) can target HepG2 cells effectively and meantime dispalys excellent biocompatibility. Therefore, the injected microgels based on P(DEGMA-co-OVNGal) have the potential to serve as a robust and promising drug delivery carrier for targeted cancer therapy.

Thermodynamics and robust n-type charge carrier density in Co-doped FeTe2: strain strategy

Herein, we investigated the combined effect of Co-doping and strain (biaxial [110] and hydrostatic [111]) on the thermodynamics and electronic structure of the FeTe2 motif using ab-initio calculations by considering the strong correlation effects. The pristine one has a non-magnetic semiconducting nature with an indirect band gap (E g ) of 0.384 eV. Interestingly, our results revealed that the Co-doping at the Fe site induced an n-type conductivity (i.e. few states are crossing the Fermi level from the valence to conduction band) in the system having a substantial charge carrier density magnitude of 0.14 × 1021 cm−3. The metallicity mainly comprises the Co-3d orbitals along with a significant contribution from Fe-3d states. Thermodynamic, mechanical, and dynamical stability of the Co-doped FeTe2 structure is confirmed by computing the formation energetic, elastic constants, and phonon band structure, respectively. Generally, an increasing and decreasing trend in E g value is evident against the applied compressive and tensile strains having ranged from −5% to +5% for the case of the undoped system, respectively. On the other hand, the Co-doped structure maintained its n-type conduction against considered both types of strains. Moreover, it is demonstrated that compressive strains strengthen the charge carrier density amplitude, while tensile strains show a negative impact. Hence, the present work displays that robust n-type conductivity and stable structure of Co-doped FeTe2 system, makes it a desirable candidate for device applications.

A Novel Approach for GNSS Signal Tracking Based on Sliding Mode Control

Designing a robust carrier tracking loop for GNSS receivers is a challenging task under strong scintillation, multipath, clock uncertainty, interference, and vehicle high dynamics. The conventional tracking methods such as proportional integral filter (PIF), Wiener filter (WF), and Kalman filter (KF) are known to perform well under given GNSS signal model parameters and noise characteristics. If it is not the case, then performance deteriorates and may result in loss of the carrier lock. To circumvent this problem, we propose a robust control and filtering method based on the well-known sliding mode approach. In this paper, a sliding mode control and state estimation framework is developed for GNSS carrier tracking. The efficacy of the proposed method is proved by simulation studies for GPS(L1) signal. From static to high dynamics operating cases are simulated for proving its usage on the high dynamics vehicles such as high speed trains, flighter jets, and missile systems. The achieved results are promising for use of the proposed method on these vehicles and the receiver operating in the adverse (weak GNSS signal) conditions.

Farm waste-eggshell nanoparticles constitute gel for safe navigation of probiotic across the stomach

Gut microbiota plays an important role in gastrointestinal health, whose colonization through oral application as probiotic faces a major challenge due to harsh acidic conditions in the stomach. Hence, an edible gel constituted of agricultural waste like eggshell particles and pectin is developed to carry the probiotic safely. The eggshell shares the surface calcium ions for gelation, core particle as gel strength reinforcement agent and calcite to neutralize the gastric pH. This robust carrier shows 60% more viability compared to the control. Interestingly, the mechanism of this compact gel formation has been found to involve the structure-directing and functional eggshell proteins. Significant improvement in the polyphenol metabolism has also been observed by this formulation. Scheme: Schematic shows Lactobacillus plantarum navigating across the stomach safely in the eggshell nanoparticles + pectin prebiotic gel.

Engineered Norovirus-Derived Nanoparticles as a Plug-and-Play Cancer Vaccine Platform.

In recent years, virus-derived self-assembled protein nanoparticles (NPs) have emerged as attractive antigen delivery platforms for developing both preventive and therapeutic vaccines. In this study, we exploited the genetically engineered Norovirus S domain (Nov-S) with SpyCatcher003 fused to the C-terminus to develop a robust, modular, and versatile NP-based carrier platform (Nov-S-Catcher003). The NPs can be conveniently armed in a plug-and-play pattern with SpyTag003-linked antigens. Nov-S-Catcher003 was efficiently expressed in Escherichia coli and self-assembled into highly uniform NPs with a purified protein yield of 97.8 mg/L. The NPs presented high stability at different maintained temperatures and after undergoing differing numbers of freeze-thaw cycles. Tumor vaccine candidates were easily obtained by modifying Nov-S-Catcher003 NPs with SpyTag003-linked tumor antigens. Nov-S-Catcher003-antigen NPs significantly promoted the maturation of bone marrow-derived dendritic cells in vitro and were capable of efficiently migrating to lymph nodes in vivo. In TC-1 and B16F10 tumor-bearing mice, the subcutaneous immunization of NPs elicited robust tumor-specific T-cell immunity, reshaped the tumor microenvironment, and inhibited tumor growth. In the TC-1 model, the NPs even completely abolished established tumors. In conclusion, the Nov-S-Catcher003 system is a promising delivery platform for facilitating the development of NP-based cancer vaccines.

Construction of hierarchical and porous cellulosic wood with high mechanical strength towards directional Evaporation-driven electrical generation

Tremendous efforts have been dedicated to harvesting energy from the ubiquitous natural water evaporation process. Inspired by the plant's bioelectric phenomenon during the transport of sap from bottom to top, the hierarchically porous cellulosic wood was engineered as the robust carrier for efficiently capturing and transferring water and moisture by removing lignin and hemicellulose, releasing the microscale pore in the cell wall and nanoscale pores in the middle lamella. A conductive polymer, poly(3,4-ethylenedioxythiophene)/poly(styrenesulfonate) (PEDOT/PSS), was impregnated in the cellulosic wood, which was further lyophilized to increase the specific surface area and improve the charge transport as an evaporation-driven electrical generator (EEG) with high Young’s modulus. This EEG produces a sustained voltage of around 385 mV and current over 11 μA across the porous and conductive cellulosic wood in a saturated NaCl solution. The anisotropic nature of the cellulosic wood leads to a higher output voltage in the growth direction than in the transverse direction. The driving force behind this energy generation is a self-maintained moisture gradient to generate an ion concentration difference between the output electrodes when the system is exposed to water or moisture. Furthermore, the critical factor of energy generation is the coupling between naturally aligned cellulose microfibrils in wood and water molecule. The generated voltage could be increased by elevating the concentration of ions in the aqueous solution and the temperature difference between the output electrodes. These strong and hierarchical cellulosic wood have a significant potential for electric energy collection through water evaporation and waste heat energy.

Asymmetrically coupled Co Single-atom and Co nanoparticle in Double-shelled Carbon-based nanoreactor for enhanced reversible oxygen catalysis

Simultaneous construction of size-asymmetric metal single atoms and nanoparticle active sites in advanced and robust carrier materials is particularly important yet challenging for efficient reversible oxygen catalysis. Herein, a facile “chemical etching/in-Situ capture” synthesis strategy was developed to fabricate a unique double-shelled carbon-based nanobox integrated with size-asymmetric Co single-atom (CoSA) and metallic Co nanoparticle (CoNP) moiety. As expected, this well-managed catalyst product yielded remarkable bifunctional electrocatalytic performances in alkaline electrolytes, with a decent half-wave potential of 0.886 V for oxygen reduction reaction (ORR) and a small overpotential of 341 mV at 10 mA/cm2 for oxygen evolution reaction (OER). Besides, this nanobox catalyst served as a cost-effective and efficient oxygen electrode in the assembled rechargeable ZABs, exceeding the mixed electrocatalyst of expensive Pt/C-RuO2, in terms of the elevated peak power density of 239 mW/cm2, the promoted specific capacity of 770 mAh/gZn, as well as the appreciable charge–discharge cycle stability. Theoretical calculations revealed that the strong interaction between the delicate CoSA site and CoNP phase, could effectively optimize the adsorption and desorption energy barriers of reaction intermediates on the designed catalyst surface, thus achieving synergistic enhancement of electrocatalytic activity towards ORR and OER. This finding affords a feasible and effective strategy to achieve highly active and durable bifunctional catalysts for both fundamental research and practical rechargeable ZABs applications.

H∞ filter-based dynamic joint carrier frequency offset and linear phase noise tracking for CO-OFDM systems.

In this paper, a robust, dynamic and joint carrier frequency offset (CFO) and linear phase noise (LPN) tracking algorithm is proposed by utilizing the H∞ filter for CO-OFDM systems. The dynamic tracking is implemented by Bayesian filtering which time-recursively updates the posterior state estimates based on the prior state information and calculated gain. To improve the robustness of the dynamic tracking process against the uncertainty of the noise terms, we adopt the H∞ filter, which designs a min-max optimization problem with a performance bound-defined constraint. The H∞ filter obtains the state estimates by limiting the worst-case estimation error, which guarantees its robustness to the system uncertain noise terms and external disturbances. After the joint estimation of CFO and LPN, we then propose a decision-feedback algorithm to achieve accurate signal detection. The accuracy and robustness of the proposed algorithm are verified in an 88.9 Gb/s 16-QAM CO-OFDM system, by comparing with the conventional extended Kalman filter (EKF) and Gaussian particle filter (GPF). Simulation results show that the MSEs of CFO and LPN by H∞ filter can reach the Cramér-Rao Lower Bounds (CRLBs) as well as the Bayesian CRLB (BCRLB), and possesses excellent noise and chromatic dispersion (CD) tolerance.

Efficient ultraviolet–visible-near infrared self-powered photodetector based on hexagonal YMnO3-based ferroelectric thin film by multiscale polarity structure optimization

The utilization of ferroelectric photovoltaic effect is thought to be an effective strategy to design novel self-powered photodetectors. However, the low photocurrent output due to the incompatibility between high intrinsic ferroelectric polarization and narrow bandgap is a major disadvantage that restricts photodetection performances. Here, high-efficiency photodetection properties are achieved in a hexagonal Y1-xBixMnO3 ferroelectric self-powered photodetector using a multiscale polarity structure optimization strategy. Particularly, the photodetector based on Y0.95Bi0.05MnO3 (YBMO5) can work in a wide band ranging from ultraviolet to near infrared with the maximum responsivity and detectivity up to 0.60 A/W and 2.50 × 1012 Jones, respectively, with the fast response time of only 0.3/0.4 ms, which are superior to the traditional ferroelectric perovskite photodetectors. The excellent photodetection performances originate from the enhanced photocurrent output, owing to simultaneously achieving big light absorption and robust photogenerated carrier separation and transport. It is demonstrated that Bi doping tunes crystal lattice, domain structure and the interface state, which effectively enhance macroscopic polarity in the condition of nearly unchanged bandgap. Moreover, a denser conductance network of grain boundary is constructed by decreasing grain size, which provides more transport paths for the photogenerated carriers. This work opens up a promising route for the design of high-performance ferroelectric photodetectors.