The ride comfort of vehicles traveling on the road has always been a concern. In addition, the braking force of vehicles will aggravate the damage to road structures and reduce the comfort of drivers and passengers. In the present study, the dynamic response of pavement, road friendliness, and human comfort are investigated by setting up the human-bus-road coupled vibration system considering the braking forces. Firstly, the three-dimensional finite element model of asphalt pavement with interlayer contact and the human-bus model with multiple degrees of freedom (2n + 7) were established to analyze the dynamic responses of asphalt pavement, human body, and bus under different braking conditions. Then, the dynamic load coefficients of wheels under different combined conditions were investigated to evaluate the road friendliness and the human annoyance rate was adopted to evaluate the human comfort. The results show that for the asphalt pavement, the shear stress of the pavement is larger than the normal stress due to the bus braking, and the combined effect of road surface roughness and braking force on the road friendliness is the largest. For the human comfort, the pitch acceleration of human body increases more than the roll acceleration due to bus braking, resulting in the decreased human comfort and increased annoyance rate.
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