This article theorizes path-dependent changes in the institutional architecture of the nuclear nonproliferation regime complex; it analyses the effects of different regime-complex structures on institutional contestation and policy adjustment. I first offer a general theory of how the preexisting institutional structures of international regime complexes (IRCs) facilitate and constrain subsequent institutional developments in ways that make IRCs prone to endogenous, path-dependent change. Next, I illustrate how strategies of regime shifting and rival regime creation in the nuclear nonproliferation complex have triggered path-dependent ‘reactive sequencing’, resulting in growing institutional fragmentation. To illustrate endogenous dynamics of IRC evolution, I examine the nuclear nonproliferation complex at three ‘critical junctures’: The mid-1970s, the end of the Cold War, and the early-2000s. During each period, exogenous proliferation shocks interacted with pre-existing institutional structures to produce specific patterns of contestation which set in motion a reactive sequence of growing institutional fragmentation. My argument has relevance for global economic governance broadly and for the growing IPE literature which explores reactive sequencing and institutional decay in global governance institutions.
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