Risky Pregnancy Research Articles

Dicliptera laxata (Acanthaceae) (C. B. Clark) Unblocks an Abamectin-Blocked Estrous Cycle and Restores Cyclicity in Female Albino Rats

The farmers of the Buea municipality, Fako Division, South-West Region, Cameroon extensively use Abamectin or Aba, a phytosanitary insecticide which targets insects such as mites, thrips species and leaf miners. In this area, the local population also uses Dicliptera laxata traditionally as a fertility enhancer and in stabilizing risky pregnancies in women. This study was aimed at evaluating the actions of Dicliptera laxata aqueous extract on the estrous cycle and reproductive system of Aba-treated female rats. A total of 30 adult female rats of the confirmed regular cycle were daily treated orally with a 2 ml/kg Abamectin for a period of 45 days, accompanied by the evaluation of the cytology of their vaginal smears at 5 days intervals. From the 46th day, they were subsequently treated with the leaf-aqueous extract of Dicliptera laxata for 15 days and were terminated on the 61st day during which blood and reproductive organs were collected for biochemical assays and relative weight indices. Chronic (45 days) exposure of normal cycled female rats to Abamectin witnessed a blockade in their estrous cycle, a significant drop in plasma estradiol and progesterone concentration, and a significant drop in the percentage weight of organs. Administration of Dicliptera laxata leaf-aqueous extract to these Aba-treated females resulted in a return to the regularity of their estrous cycle, with animals receiving the 300 mg/kg dose of plant extract recording a 60% regulation in the first week and 100% in the second week as compared to animals treated with distilled water that recorded a 0% and 20% regulation in the first and second week of treatment, respectively. Also, the animals that received 300 mg/kg body weight of the extract registered significant (p < 0.05) rise in plasma concentrations of progesterone and estradiol (36.44 ± 1.69 pg/mL and 77.73 ± 3.82 pg/mL, respectively) as compared to animals that received distilled water which showed 22.54 ± 2.19 pg/mL plasma progesterone and a 44.90 ± 7.63 pg/mL plasma estradiol concentrations, respectively. The actions of the leaf-aqueous extract of D. laxata could be attributed to the presence of phytochemicals including steroids, phenolic compounds, alkaloids and saponins in our extract, which have been reported to have important pharmacological effects on female reproduction. D. laxata, therefore, constitutes a potential treatment of female infertility and our findings justify its folkoric use by the Bakweri tribe in enhancing fertility. It can be used to stalize risky pregnancies and prevent miscarriages.

Machine Learning Models for Predicting Risky Pregnancies in Early Clinical Interventions

Background: Risky pregnancies present significant challenges in maternal healthcare, often requiring accurate prediction to prevent adverse outcomes. Machine learning (ML) models offer a promising approach for predicting such risks, enabling timely interventions. This study evaluates five machine learning models—Logistic Regression, Decision Tree, K-Nearest Neighbors (KNN), Naive Bayes, and Support Vector Machine (SVM)—for their effectiveness in predicting risky pregnancies using clinical datasets. Methods: The study developed and evaluated five ML models, each implemented using Python’s scikit-learn library. The dataset was split into 75% for training and 25% for testing. Standard classification metrics, including accuracy, precision, recall, and F1-score, were used to assess model performance. Hyperparameter tuning was conducted using grid search and cross-validation to optimize model parameters. The models’ performance was compared to identify the most suitable for clinical applications. Results: The Decision Tree model achieved the highest accuracy (100% on training data, 95.6% on testing data), along with excellent precision, recall, and F1-scores for both classes, making it the most accurate and interpretable model for predicting risky pregnancies. Logistic Regression also performed well, particularly in identifying high-risk cases, with testing accuracy of 82%. KNN and SVM provided moderate accuracy, with KNN achieving 78% testing accuracy and SVM 80%. Naive Bayes, however, performed poorly, achieving only 43.2% accuracy due to its assumption of feature independence, which was not suitable for the dataset. Conclusion: The Decision Tree and Logistic Regression models emerged as the most effective for predicting risky pregnancies, offering high accuracy and interpretability, crucial for clinical decision-making.

History of Risky Pregnancies and Failure of Exclusive Breastfeeding in Indonesia

The coverage of exclusive breastfeeding for infants in Indonesia still needs to be higher compared to the national target (80%). Low coverage of exclusive breastfeeding is a risk factor for various nutritional problems in toddlers. The causes of failure of exclusive breastfeeding are multifactorial, including risky pregnancy. This study aims to determine the association of risky pregnancies with the failure of exclusive breastfeeding using national data from the 2017 Indonesian Health Demographic Survey (IDHS) with a cross-sectional design. The study sample that met the criteria was 6,689 mothers with children aged 6-23 months. The independent variable is risky pregnancy (parity, pregnancy spacing, age during pregnancy), and the dependent variable is the failure of exclusive breastfeeding. Data analysis using multivariate logistic regression. The results found that only 26.2% of exclusive breastfeeding practices. Risky pregnancy is associated with the failure of exclusive breastfeeding. Mothers with too much parity risked 1,195 times, mothers with primiparous parity risked 1,716 times, too close birth spacing risked 1,210 times, and too young mothers were 1,267 times more likely not to exclusively breastfeed than mothers who had normal pregnancies after controlling for the area of residence. It is necessary to improve health promotion programs to the public regarding the importance of offering exclusive breastfeeding to infants and improving fertility characteristics.

Edukasi tentang Kehamilan Risiko Tinggi melalui Kunjungan Rumah di Kelurahan Mojosongo Jebres Surakarta

Antenatal and postnatal home visiting programs provide significant benefits in improving the health of mothers and babies. Risky pregnancies have the potential to experience life-threatening complications for the mother (85.4%), maternal near misses (13.3%), and maternal death (1.2%). This activity aims to provide education about high-risk pregnancies through home visits. The method is education about high-risk pregnancies using a home visit approach. Location in the Mojosongo Village area, Jebres, Surakarta, Central Java, Indonesia. Activities begin with licensing, preparation, and coordination with the community officer team and study program team, implementation, and evaluation. The results showed that pregnant women had no risk were 56% and high risk were 44%. Risk factors for pregnancy were old age > 35 years, grand multigravida, and hypertension in pregnancy. Mothers are invited to actively read the MCH books, actively discuss, and cooperate. The hope is that pregnant women and their husbands will actively increase their knowledge about healthy pregnancy planning, preparation for childbirth, and newborn babies. Develop an integrated information system for pregnant women that can be accessed by pregnant women. Training program for community officers to improve their ability to assist pregnant women.

Bioelectrical Impedance in Premature Newborns and Its Relationship with Diet Therapy in a Neonatal Intensive Care Unit.

(1) Background: To estimate resistance, reactance, and phase angle values among moderate preterm infants and their variation according to neonatal and maternal characteristics and nutritional intake. (2) Methods: This was a cohort that evaluated 43 moderate preterm infants using bioelectrical impedance analysis. The study variables included resistance, reactance, and phase angle measurements, in addition to classification of nutritional intake. (3) Results: Mean resistance was 602.0 ± 118.2 Ω, reactance was 57.2 Ω (IQR = 42.6-65.2), and phase angle was 522° (IQR = 4.1-6.6). Lower resistance values were found in the presence of risky pregnancy (532.2 ± 111.9 Ω vs. 650.9 ± 97.9 Ω, p < 0.001) and lower reactance values, in the presence of harmful maternal lifestyle habits at both the first (p = 0.01) and second assessments (p = 0.01). Eight preterm infants were considered to have insufficient nutritional intake (23.5%); 17, sufficient (50.0%) and 9, partially sufficient (26.5%). There was less reactance among preterm infants with insufficient nutritional intake (p < 0.001). (4) Conclusions: The bioelectrical impedance analysis measurements were within the range of values reported in other studies. There was an association between full diet and adequate nutritional intake with higher resistance values, while a lower reactance value was associated with the presence of risky pregnancy and harmful maternal lifestyle.

Upaya Peningkatan Kesehatan Ibu Dan Anak Yang Service Excellent Melalui Edukasi Pengetahuan Penyulit Kehamilan Dengan Sigap Resti Di PMB Marshinta Sirait Medan Polonia Tahun 2024

Parameters for measuring public health conditions can be studied through the maternal mortality rate (MMR) and infant mortality rate (IMR) that occur in each period. Education is one of the efforts to improve the level of health, increasing knowledge about health will change a person's attitudes and behavior regarding health. Health. Apart from using the lecture method, providing this education also provides leaflets to support the education. This community service activity is carried out by providing education through lectures assisted by modified media about risky pregnancies, complications of pregnancy, as well as about strengthening the detection of complications with alacrity and rest. Method: This activity begins with the preparation, implementation and evaluation stages. Results: 15 participants in this activity were pregnant women who visited the Marsinta Clinic in Polonia District, Medan City. In its implementation, risky pregnancies, complications in pregnancy are explained as well as strengthening understanding about fast rest as an empowerment for pregnant women in improving their health. Conclusion: The results obtained from this community service activity were an increase in knowledge about risky pregnancies before and after, namely an increase of 15% for the good level of knowledge, and 27% for the sufficient level, and at the level of poor knowledge there was a decrease of 40%. With this change in the level of knowledge and the strengthening of understanding, it is hoped that pregnant women will be more aware of the condition of their pregnancy and carry out pregnancy checks more regularly.

Identification of Posttraumatic Stress Disorder Symptoms and Concerns Regarding Childbirth and Postpartum Period in Risky Pregnancies

Amaç: Kadının riskli gebelik tanısı alması, bebeğini kaybetme korkusu ve destek faktörlerinin yetersizliği endişe düzeylerini artırabilmekte ve posttravmatik stres bozukluklarına da neden olabilmektedir Araştırma, yüksek ve düşük riskli gebelerde posttravmatik stres bozukluğu belirtileri, doğum ve doğum sonrası döneme ilişkin endişelerin belirlenmesi amacı ile yapılmıştır.&#x0D; Yöntem: Araştırma kesitsel desende yürütülmüştür. Çalışmanın örneklemini bir devlet hastanesinin gebe ve jinekoloji servislerine yüksek riskli gebelik tanısı ile yatan (n=306), kadın hastalıkları ve doğum polikliniğine kontrol amacı ile başvuran (n=306) toplam 612 gebe oluşturmuştur. Veriler Kişisel Bilgi Formu, Posttravmatik Stres Bozukluğu Soru Listesi-Sivil Versiyonu, Doğum ve Doğum Sonrası Döneme İlişkin Endişeler Ölçeği ile toplanmıştır. &#x0D; Bulgular: Yüksek riskli gebelerin %48.4’ünde ve düşük riskli gebelerin %29.4’ünde posttravmatik stres bozukluğu belirtileri olduğu saptanmıştır. Yüksek ve düşük riskli gebelerde toplam Posttravmatik Stres Bozukluğu Soru Listesi-Sivil Versiyonu ve toplam Doğum ve Doğum Sonrası Döneme İlişkin Endişeler Ölçeği puanları arasında istatistiksel olarak anlamlı farklılık bulunmuştur (p

Edukasi Pemilihan Alat Kontrasepsi Pada Wanita Usia Subur, Pasangan Usia Subur Dan Ibu Nifas

The family planning program is the main pillar in preventing risky pregnancies and reducing maternal mortality and infant mortality. the prevalence of contraceptive use by married women is projected to be 62.2%. The percentage continues to increase until it reaches 64.4% in 2030. The level of achievement in the use of contraceptives can be seen from the coverage of couples of childbearing age and postpartum mothers. The number of mothers giving birth in 2021 will be 25,430 who will become new family planning participants. The importance of educating the public is to increase understanding regarding the selection of appropriate contraceptives for couples of childbearing age and postpartum mothers. The aim of this education is to increase knowledge regarding the selection of appropriate contraceptives, especially for couples of childbearing age and postpartum mothers. This education uses community service methods with outreach to women and couples of childbearing age and also post partum mothers, using power points and pamphlets. The results of this education showed an increase in public knowledge during the pretest and posttest.

The Relationship of Knowledge and Husband's Support With The Use of Injective Contraceptions

The family planning (KB) program is a government effort to prevent risky pregnancies due to the 4Ts (too young, too old, too close, and too frequent). One of the birth control methods most widely used by women of childbearing age (WUS) is injectable birth control. The research aims to determine the relationship between a husband's knowledge and support and the use of injectable contraceptives in women of childbearing age. Method: quantitative research using a cross-sectional design with a cluster random sampling technique. Data were collected using a questionnaire, and analysis was carried out using the Chi-Square statistical test. Results: There is a relationship between knowledge (p-value 0.046) and husband's support (0.001) with the use of injectable contraceptives in women of childbearing age (WUS) in the Tanjung Pinang Health Center Working Area, Jambi. Conclusion: There is a relationship between a husband's knowledge and support and the use of injectable contraceptives in WUS, so it is hoped that health workers will routinely provide outreach regarding the use and benefits of injectable contraceptives to couples of childbearing age (PUS).

Analysis of Risk Factors and Risky Pregnancies Among Pregnant Women Who Admitted to Hospital for Prenatal Care

Objective: Every woman wants to have a healthy pregnancy and have a healthy baby, but it brings important risks. Risky pregnancies are with many different dimensions that negatively affect maternal and infant health. The aim of this study is to determine the frequency of risk factors leading to risky pregnancies which are important for public health, to reveal the reasons and to offer solutions. &#x0D; Methods: This is a cross – sectional study of 409 married women who applied to the hospital for prenatal care. A questionnaire prepared by the researchers was used for data collection by face-to-face interview technique. Percentage, mean, and chi-square test were used to evaluate the data.&#x0D; Results: Although pregnancy is a physiological process, 67.7% of the pregnant women had at least one risk factor and 27.6% had more than one risk factor. Risk factors such as having caesarean section, having four or more pregnancies, being 35 and over age, unwanted pregnancy status and having less than two years between the last two pregnancies were found to be the most common risk factors seen in pregnant women.&#x0D; Conclusion: Because risky pregnancies are an important public health problem and most of them are preventable; preconceptional care should be expanded to control the mother and baby before threatening their health.

Anthropometric analysis of Turkish fetuses’ face

Aims: This study aims at collecting data on the morphology of the face during its development in order to get detailed information on the neighboring structures and its variations using anatomical dissections and obtain normal morphometric values of the face growth and human fetuses during the 1st, 2nd and 3rd trimester.&#x0D; Methods: This study was performed on spontaneously aborted 97 fetuses (49 males, 48 females) (11 first trimester, 63 second trimester and 24 third trimester) that have no observable congenital malformations or maternal history of risky pregnancy. The fetuses were taken from a Gynecology Department of a School of Medicine and a Maternity Hospital in Konya. Thirteen direct facial anthropometric measurements were performed on 97 volunteers. The data obtained were compared with the data of previous studies.&#x0D; Results: Means and standard deviations of the parameters in regard to gestational weeks and trimesters were calculated. A significant correlation was observed between all parameters and gestational age (p

Training of Health Cadres in strengthening Assistance Program for Pregnant Women in the Region Arjowinangun Malang Community Health Center

Maternal Mortality Rate (MMR) is an indicator of the impact of health development. The Maternal Mortality Rate (MMR) causes of are direct and indirect factors. These two factors can be prevented through prevention efforts based on community empowerment. One effort that can be made to empower the community is through empowering health cadres. This activity can be carried out through training to carry out pregnancy assistance by cadres. The aim of this training activity is to increase health cadres' knowledge about mentoring programs for pregnant women and skills in providing communication, information and education (KIE) related to the health of pregnant women and early detection of risky pregnancies. The method used is cadre group-based training in the Arjowinangun Malang Community Health Center area. The activity takes the form of cadre training regarding health assistance for pregnant women by health cadres. The results of this research showed that there was an increase in pre and posttest scores (74.6% in the sufficient category, to 91.15% in the good category). Meanwhile, the skills evaluation was in the good category (85.42%). The conclusion is that refreshing the material for cadres is necessary for optimal assistance for pregnant women. This pregnancy assistance program by cadres should become a Community Health Center program whose implementation also receives full support from the village government, and there are ongoing monitoring and evaluation efforts.

Benefits of Adolescent Women's Reproductive Health Records as a Basis for Screening Preconception Care: A Research and Development Study

The health status of women is one of the factors that can affect the status of pregnancy. To avoid risky pregnancies and produce healthy babies, it is very important for a woman to take care of her reproductive health. One of the efforts is to conduct early detection on a regular basis starting from the age of teenagers. This developmental research was carried out using the Four-D model, to obtain a simple early detection medium in preconception care. Sixty selected young women participated in a limited trial. Respondents who participate in a limited-scale trial will go through 3 stages. The data obtained were analyzed descriptively. The success of using the application as a function of simple screening media for preconception care reached 96.67%. It was identified that 57% of adolescent girls were detected to have health problems such as poor nutritional status and anemia. A total of 71.7% stated that this application applies very well on adolescent girls in order to keep them healthy as an initial step in preparation for pregnancy. As many as 73.3% of respondents stated that the developed application provided new knowledge related to preconception preparation. There is strong evidence that the resulting media performs well as a simple early detection tool for preconception care. Therefore, it needs to be refined to provide more optimal results.&#x0D; Keywords: screening, preconception, adolescent

Sickle cell anemia in pregnant Saudi women and its impact on birth weight and gestational maturity.

It is well documented that sickle cell anemia (SCA) in pregnancy increases the risk of problems that can influence the growth and maturation of the newborn. To assess the gestational maturity and birth weight of babies born to Saudi mothers with SCA in the Jazan region. A case-control study was conducted in three hospitals in the Jazan region. An interview with a semi-structured questionnaire was used to collect data from the participants' women, and then the birth weight was taken. Of 187 delivered women, 20.3% had SCA (13% had sickle cell disease, and the remaining had sickle cell trait). Among the 38 affected mothers, 15.7% were considered to have an additional risk (7.9% had diabetes mellitus, 5.3% had hypertension, and 2.6% were smokers). The mean birth weight was 2.95 ± 0.40 kg and 2.99 ± 0.55 kg in the case and control groups, respectively. However, the low birth weight babies constitute 31% of the delivered babies in the SCA group with a weight of 2.33 ± 0.16 kg and 15% of the control group with a mean weight of 2.16 ± 0.30 kg. The gestational age was 39.36 ± 1.02 weeks in the SCA group compared to 39.5 ± 1.17 weeks in the control group. Maternal age and hypertension significantly influence the birth weight in the SCA group compared to the influence of diabetes mellitus on the birth weight in the control group. This study indicates that SCA in pregnant mothers influences birth weight, which is more impacted by maternal age and co-morbidities. Therefore, a multidisciplinary approach must monitor these risky pregnancies well to avoid undesirable neonatal outcomes.

Cholesterol Metabolic Profiling of HDL in Women with Late-Onset Preeclampsia.

A specific feature of dyslipidemia in pregnancy is increased high-density lipoprotein (HDL) cholesterol concentration, which is probably associated with maternal endothelium protection. However, preeclampsia is most often associated with low HDL cholesterol, and the mechanisms behind this change are scarcely explored. We aimed to investigate changes in HDL metabolism in risky pregnancies and those complicated by late-onset preeclampsia. We analyze cholesterol synthesis (cholesterol precursors: desmosterol, 7-dehydrocholesterol, and lathosterol) and absorption markers (phytosterols: campesterol and β-sitosterol) within HDL particles (NCSHDL), the activities of principal modulators of HDL cholesterol's content, and major HDL functional proteins levels in mid and late pregnancy. On the basis of the pregnancy outcome, participants were classified into the risk group (RG) (70 women) and the preeclampsia group (PG) (20 women). HDL cholesterol was lower in PG in the second trimester compared to RG (p < 0.05) and followed by lower levels of cholesterol absorption markers (p < 0.001 for campesterolHDL and p < 0.05 for β-sitosterolHDL). Lowering of HDL cholesterol between trimesters in RG (p < 0.05) was accompanied by a decrease in HDL phytosterol content (p < 0.001), apolipoprotein A-I (apoA-I) concentration (p < 0.05), and paraoxonase 1 (PON1) (p < 0.001), lecithin-cholesterol acyltransferase (LCAT) (p < 0.05), and cholesterol ester transfer protein (CETP) activities (p < 0.05). These longitudinal changes were absent in PG. Development of late-onset preeclampsia is preceded by the appearance of lower HDL cholesterol and NCSHDL in the second trimester. We propose that reduced capacity for intestinal HDL synthesis, decreased LCAT activity, and impaired capacity for HDL-mediated cholesterol efflux could be the contributing mechanisms resulting in lower HDL cholesterol.

EE412 Analyzing the Financial Impact of a Remote Fetal Monitoring Solution Introduction for High-Risk Pregnancies in a US Obstetrics Clinic

Self-applied remote fetal monitoring allows mothers with risky and complicated pregnancies to check maternal and fetal well-being at home while an obstetric specialist remotely monitors the results. This economic evaluation aimed to estimate a potential increment in revenues and savings for a US obstetrics clinic that would result from implementing remote fetal monitoring.

Fuzzy Inference System for The Risks Pregnancy Detection

Abstract&#x0D; One of the causes of the high Maternal Mortality Rate (MMR) and Infant Mortality Rate (IMR) in Aceh is the delay in handling cases of at risk pregnancies due to the lack of availability of easily accessible and well-documented information about conditions during pregnancy. So far, manual reporting through data recapitulation report was difficult to access quickly if there are cases maternal and infant mortality. Fuzzy logic can be used as an alternative for classifying pregnant women at risk with supporting data when examining pregnant women. Data related to pregnancy checks will be analyzed with a Fuzzy Inference System (FIS) to obtain information on pregnancy risks. The results of this study indicate that FIS can determine the risk of pregnancy more detailed range than using a manual scoring card. The results of the defuzzyfication value will describe the final decision related to pregnancy risk which can be categorized into low risk, high risk and very high risk. The problem solving steps in this study can be used for algorithms in the development of application programming for risky pregnancy early detection systems based on programming languages. ​​

Türkiye’nin bir güneydoğu ili Adıyaman’da Covid-19 pandemi sürecinde bebek ölümlerinin değerlendirilmesi

Aim: Evaluation of infant deaths during the Covid-19 Pandemic period in Adıyaman, a southeastern province of Turkey. Materials and Methods: All infant mortality files submitted to Adıyaman Provincial Health Directorate Infant Mortality Investigation Commission in 2020 and 2021 were examined. Results: 109 out of 11.019 live births in Adıyaman in 2020 and 135 of 11.979 live births in 2021 died before their first birthday. While the infant mortality rate was 9.9 per thousand in 2020, in 2021, it increased by 24% to 12.3 per thousand. There was no evidence that the Covid-19 pandemic directly increased infant mortality. Conclusion: A significant portion of infant deaths are babies of mothers who had risky pregnancies. Therefore, all steps to protect maternal health will be the first and most effective way to reduce infant mortality.

Perceived Stress in Risky Pregnancy: A Scale Development Study

Perceived Stress in Risky Pregnancy: A Scale Development Study

Faktor-Faktor Yang Berhubungan Dengan Kejadian Stunting Di Wilayah Kerja Puskesmas Siulak Mukai Kabupaten Kerinci

Stunting is a serious nutritional problem that is evident from shorter body length or height in children under five compared to children of the same age. The prevalence of stunting in Indonesia increased from 2010 to 2013, from 35.6% to 37.2%. The factors that influence the incidence of stunting in children are maternal age, pregnancy distance, maternal history of disease, nutritional status during pregnancy, and LBW. The purpose of this study was to determine the factors associated with the incidence of stunting in the Siulak Mukai Health Centre Working Area, Kerinci Regency in 2023. This type of research is descriptive analytic with cross sectional design. This research was conducted in April-August 2023. The population is the mother of infants 0-2 years as many as 192 people and a sample of 66 people taken by Systematic Random Sampling. Data analysis consisted of univariate analysis and bivariate analysis using the chi-square statistical test. The results showed that a small proportion (19.7%) of toddlers were stunted, the age of mothers at risk was only 5 people (7.6%), less than half (21.2%) of respondents with risky pregnancy distance, more than half (54.5%) of respondents with a history of disease during pregnancy, less than half (24.2%) of respondents with nutritional status during pregnancy were not appropriate, and respondents with LBW children were only 6 people (9.1%). There was a significant association between maternal age (0.048), maternal history of disease (0.034), nutritional status during pregnancy (0.001), and LBW (0.012) with the incidence of stunting and there was no significant association between gestational distance (1.000) with the incidence of stunting. Therefore, there is a significant relationship between maternal age, maternal history of disease, nutritional status during pregnancy, and LBW with the incidence of stunting and there is no significant relationship between pregnancy spacing and the incidence of stunting in the working area of Puskesmas Siulak Mukai, Kerinci Regency in 2023.