Right Nostril Research Articles

The Reliability of Polyvinylidene Fluoride Sensor for Intra- and Intersession Measurements.

A new nasal sensor has been designed using Polyvinylidene fluoride (PVDF) film using its piezoelectric property to measure nasal patency. The aim of this study is to determine the intra- and intersession reliability of the new PVDF nasal sensor measurement of unilateral and combined nasal parameters in a group of healthy subjects. Two identical nasal sensors: for right nostril (RN) and left nostril (LN) were designed using piezoelectric natured PVDF films. Twenty subjects were studied. To evaluate the repeatability, total three sets of PVDF sensor measurements were recorded, two sets were taken 5min apart during same session without repositioning the PVDF nasal sensors and two more sets were taken during 1h apart successively, by repositioning the PVDF nasal sensor. Intraclass correlation coefficients (ICC) of PVDF sensor measurements for intra- and intersession showed a high and greater repeatability over time for all the combined (mean) and unilateral (RN and LN) values. In both healthy and patients, ICC values for both intra- and intersession measurements were ≥ 0.80 confirming strong reliability and also almost all of the coefficients of variation for the same parameters were low (below 10%). PVDF sensor measurements showed good intra- and intersession repeatability and can be recommended for the objective monitoring of nasal patency during diagnosis and follow-up of conditions.

A new scheme for reducing breathing trouble through MEMS based capacitive pressure sensor

In this paper, a treatment of respiratory disorders with brushless DC motor (BLDC) driven positive airway pressure (PAP) respirator is developed. The proposed schema of the system consists of a BLDC motor driven blower fan aided by a MEMS capacitive type pressure sensor to measure respiration rate (RR). To measure the respiration rate, the array of such sensors are mounted below right nostril (RN) and left nostril (LN), in such a way that the nasal airflow during inspiration and expiration impinge on the sensor diaphragms directly. Due to irregularities in nasal airflow in some respiratory diseases, the RR varies from the normal rate (12---20). Thus, a supporting airflow regulatory system has been designed to reduce abnormalities in RR. The supporting system consists of a positive airway pressure (PAP) respirator with a blower fan to relieve patients breathing abnormalities. The MEMS based RR sensors help to monitor patients breathing rate continuously and finally maintain the required air pressure/flow by regulating the rpm of the blower fan through BLDC motor drive. In order to implement such a control action, we have chosen the sensorless drive of BLDC motor to construct a transportable as well as noise immune system. An algorithm has been developed to sustain normal RR for both bradypnea (RR 20), which puts into operation through ATmega 328 to facilitate high level precision controlled action. The control system alongwith the sensory part occupies limited space in few centimeters with light weight. As a result, the electronics of the whole system can be easily mounted at the outer surface of the tube connected with the nasal mask. The scheme of such a portable and cost effective system is described in this present work.

Validation of polyvinylidene fluoride nasal sensor to assess nasal obstruction in comparison with subjective technique

ObjectiveThe aim of this study is to validate the applicability of the PolyVinyliDene Fluoride (PVDF) nasal sensor to assess the nasal airflow, in healthy subjects and patients with nasal obstruction and to correlate the results with the score of Visual Analogue Scale (VAS). MethodsPVDF nasal sensor and VAS measurements were carried out in 50 subjects (25-healthy subjects and 25 patients). The VAS score of nasal obstruction and peak-to-peak amplitude (Vp-p) of nasal cycle measured by PVDF nasal sensors were analyzed for right nostril (RN) and left nostril (LN) in both the groups. Spearman's rho correlation was calculated. The relationship between PVDF nasal sensor measurements and severity of nasal obstruction (VAS score) were assessed by ANOVA. ResultsIn healthy group, the measurement of nasal airflow by PVDF nasal sensor for RN and LN were found to be 51.14±5.87% and 48.85±5.87%, respectively. In patient group, PVDF nasal sensor indicated lesser nasal airflow in the blocked nostrils (RN: 23.33±10.54% and LN: 32.24±11.54%). Moderate correlation was observed in healthy group (r=−0.710, p<0.001 for RN and r=−0.651, p<0.001 for LN), and moderate to strong correlation in patient group (r=−0.751, p<0.01 for RN and r=−0.885, p<0.0001 for LN). ConclusionPVDF nasal sensor method is a newly developed technique for measuring the nasal airflow. Moderate to strong correlation was observed between PVDF nasal sensor data and VAS scores for nasal obstruction. In our present study, PVDF nasal sensor technique successfully differentiated between healthy subjects and patients with nasal obstruction. Additionally, it can also assess severity of nasal obstruction in comparison with VAS. Thus, we propose that the PVDF nasal sensor technique could be used as a new diagnostic method to evaluate nasal obstruction in routine clinical practice.

A New Scheme for Determination of Respiration Rate in Human Being using MEMS Based Capacitive Pressure Sensor: Simulation Study

Abstract In this paper, a MEMS based capacitive nasal sensor system for measuring Respiration Rate (RR) of human being is developed. At first two identical diaphragm based MEMS capacitive nasal sensors are designed and virtually fabricated. A proposed schematic of the system consists of signal conditioning circuitry alongwith the sensors is described here. In order to measure the respiration rate the sensors are mounted below Right Nostril (RN) and Left Nostril (LN), in such a way that the nasal airflow during inspiration and expiration impinge on the sensor diaphragms. Due to nasal airflow, the designed square diaphragm of the sensor is being deflected and thus induces a corresponding change in the original capacitance value. This change in capacitance value is to be detected by a correlated- double-sampling (CDS) capacitance-to-voltage converter is designed for a precision interface with a MEMS capacitive pressure sensor, followed by an amplifier and a differential cyclic ADC to digitize the pressure information. The designed MEMS based capacitive nasal sensors is capable of identifying normal RR (18.5±1.5 bpm) of human being. The design of sensors and its characteristics analysis are performed in a FEA/BEA based virtual simulation platform.

Piezoelectric Sensing: Evaluation for Clinical Investigation of Deviated Nasal Septum

Noninvasive objective evaluation of nasal airflow is one of the important clinical aspects. The developed polyvinylidene fluoride (PVDF) sensor enables measurement of airflow through each side of the nose using its piezoelectric property. This study was designed to evaluate the diagnostic capability of the PVDF sensor in assessing the deviated nasal septum (DNS). PVDF nasal sensor uses its piezoelectric property to measure the peak-to-peak amplitude (Vp-p) of nasal airflow in both of the nostrils: right nostril (RN) and left nostril (LN), separately and simultaneously. We have compared the results of PVDF nasal sensor, visual analog scale (VAS), and clinician scale for 34 DNS patients and 28 healthy controls. Additionally, the results were further analyzed by receiver operating characteristic curve and correlation between PVDF nasal sensor and VAS in detecting DNS. We found a significant difference in the peak-to-peak amplitude values of the test group and the control group. The correlation between the PVDF nasal sensor measurements and VAS (RN and LN combined) for test group was statistically significant (−0.807; p < 0.001). Sensitivity and specificity of the PVDF nasal sensor measurements in the detection of DNS (RN and LN combined) was 85.3 and 74.4%, respectively, with optimum cutoff value ≤0.34 Vp-p. The developed PVDF nasal sensor is noninvasive and requires less patient efforts. The sensitivity and specificity of the PVDF nasal sensor are reliable. According to our findings, we propose that the said PVDF nasal sensor can be used as a new diagnostic tool to evaluate the DNS in routine clinical practice.

ADAMANTINOMA OF THE FLOOR OF THE RIGHT NOSTRIL: Occurrence in a Child Aged Five Years

The difficulty in recognition of the presence of a slow-growing malignant neoplasm involving the floor of the right nostril in a child aged 5 years prompts the report of this case. At the first observation the lesion had the picture of a furuncle involving the nasal floor. The adamantinoma is a slow-growing tumor, insidious in onset. The symptoms may be so slight that not until the tumor has advanced can it be recognized clinically. Roentgenograms of the teeth and sinuses are inconclusive. It is a tumor that destroys by invasion and secondary infection. It is resistant to roentgen radiation but does respond to a degree, as this case demonstrates. The adamantinoma arises from cells concerned with tooth development and is classified under the general heading of epithelial odontomas. It is multilocular and microscopically shows masses of epithelial cells of the enamel organ type of ameloblasts, cuboidal cells and stellate reticulum.