Restrictive Regulations Research Articles

Breakup dynamics in a pressure-swirl injector for urea-water solution applications: A computational study

The co-optimization of in-cylinder combustion and after-treatment technology has become a major aspect in engine design and development, with the goal of meeting the increasingly restrictive emission regulations in the transportation industry. Selective Catalytic Reduction is a robust technology to control the emission of NOx, and the injection of urea in water solution is the exhaust tailpipe is a key aspect of its operation. The proposed work uses high-fidelity Computational Fluid Dynamics to characterize the atomization dynamics of the liquid jet in relevant cross-flow conditions. The study focuses on a commercial low-pressure (9 bar) pressure-swirl injector which is characterized in its internal geometry through high-resolution X-ray micro-computational tomography. The internal two-phase flow has been modeled according to the volume-of-fluid approach in a large eddy simulation framework and validated against near-nozzle X-ray radiography measurement. Moreover, characterizing the breakup dynamics for the swirling hollow cone formation, and assessing the influence of the cross-flow in the breakup dynamics was completed. The results have been reported proposing Re-Oh maps and probability density functions of the spray kinematics. Higher cross-flow momentum generates an increase in the jet intact length and a reduction of the liquid droplet diameters. The axial momentum of the jet is affected by the cross-flow already in the near-nozzle region, determining a relevant deviation of the spray velocities. This work aims to inform the initialization of Eulerian-Lagrangian spray models through the assignment of droplet kinematics and static one-way coupling between volume-of-fluid results and Lagrangian spray parcels, to be used for system-size domain simulations.

Struggles of vehicle residents in Squamish: Challenging the capitalist and colonial institution of housing

In this conversation, Thomasina Pidgeon discusses her decision to live in a vehicle in Squamish, north of Vancouver, in British Columbia, Canada. This was a choice originally driven by the lack of affordable housing, but she continued with it after falling in love with life on the road. Her story sheds light on the broader issues of housing, gentrification, and societal attitudes toward non-sedentary life choices. For Thomasina, living in a vehicle offered a sense of freedom for her and her daughter, despite occasional problems, as well as a deep connection with nature that conventional housing couldn’t provide. However, as Squamish has grown more gentrified, particularly after the 2010 Olympics, the town has increasingly cracked down on vehicle residents, categorising them as unhoused and treating them as a problem. These restrictive regulations, according to Thomasina, are part of a larger system that prioritizes property values and profits over human needs, echoing colonial practices that forced nomadic communities to settle for the benefit of those in power. Her story calls for a shift in how we think about housing, urging us to go beyond housing as a capitalist and colonial institution, and towards a deeper understanding of the systemic issues that lead to the so-called housing crisis. Despite facing stress and anxiety due to these crackdowns, Thomasina continues to advocate for the rights of vehicle residents with the organization Vehicle Residents of Squamish, and to connect different struggles from Palestinian solidarity work to struggles against an LNG terminal.

E-cigarette retail outlets in Mexico: a country that bans the sale.

Restrictive e-cigarette policies have not allowed for the characterization of the sale of these tobacco products in the countries where they are implemented. This is because it is believed that there are no stores. However, the use of e-cigarettes persists in these countries. A content analysis of electronic cigarette points of sale through the internet in Mexico was conducted. Cross-sectional study. Structured searches were performed in the Google Maps search engine with the terms "electronic cigarette store" and "vape store" in combination with the name of each state of Mexico, in the period from October 2021 to February 2022. A total of 695 e-cigarette stores were located, of which 481 (69.2%) were physical stores, 207 hybrid stores (29.8%), 4 online stores (0.6%) and 3 (0.4%) vending machines. A total of 316 e-cigarette brands and 578 vape liquid brands were identified. The sales attraction strategy they used the most was free shipping of products (85.8%). Stores used WhatsApp (92.5%), Facebook (86.3%) and Instagram (74.4%) to promote their products. Only 35.1% of stores checked the age of their customers, of which, 95.9% asked if the customer was of legal age and 4.1% asked for the date of birth. In addition, 25.6% of the stores warned about nicotine addiction and 24.2% specifically about the ingredients of the liquids. E-cigarettes are widely available and marketed in a variety of retail outlets in Mexico. The high number of stores, brands of liquids, and e-cigarettes indicates non-compliance with existing regulations. E-cigarette consumption has increased globally, even in countries with restrictive regulations. However, there is limited data on the density and characteristics of vape stores in low- and middle-income countries with restrictive regulations. This study found no significant differences in e-cigarette sales between countries with permissive and restrictive regulations. Therefore, it is suggested that, in addition to establishing restrictive policies on the sale of e-cigarettes, their enforcement should also be monitored. Countries with restrictive measures should regulate Internet sales and promotion of e-cigarettes with greater emphasis.

Contribution of Onshore Power Supply (OPS) and Batteries in Reducing Emissions from Ro-Ro Ships in Ports

Increasingly restrictive environmental regulations for the maritime sector have led shipping companies to look for technological alternatives to reduce emissions. This article introduces a methodology to analyse emission reductions of ships in port by incorporating batteries into the ships or using an onshore power supply system. These have not yet been considered together for comparison or with a focus on ship operation. The aim is to avoid the use of auxiliary engines in ports. First, the cost calculation method to be used is specified; then, the engine’s behaviour and the established basic navigation criteria are analysed; and finally, different alternatives are considered. A methodology is afterwards defined for selecting alternatives, comparing their costs with those of using auxiliary engines in port. As an example, it is applied to a Ro-Ro route between the ports of Montoir (France) and Vigo (Spain). The results indicate that incorporating batteries into the ship produces greater savings in annual costs than onshore power supply. The cost savings from onshore power supply depend on the range of prices in each port. However, the greatest emission savings are obtained by using the onshore power supply. This methodology can be extrapolated to other routes and vessels by incorporating real operating data.

Regional Variance of Rates of Involuntary Admission in Switzerland

Identification of predictors that contribute to explaining regional variance of involuntary admission (IA) in Switzerland. Multiple regression analysis including potential predictors and regional rates of IA at the level of utilisation-based care regions. Authorisation to issue involuntary admission, assistance/guardianship, outpatient consultation rate in psychiatric practices, hospitalisation rate and urbanisation are significantly related to regional variation in IA rates. Restrictive regulation of the authority to issue IA and voluntary outpatient psychosocial and administrative support measures can contribute to a reduction in the rates of IA.

Multi-site comparison and source apportionment of equivalent Black Carbon mass concentrations (eBC) in United States: Southern California Basin and Rochester, New York,

Spatial and temporal variability of equivalent black carbon (eBC) mass concentrations were studied using Aethalometers (AE33 and AE21) at 10 sites, including 5 urban and 5 near-road across the south coast of California and New York-Rochester. Statistical methods were applied to perform intra-urban and multi-site comparisons. Given that nominal eBC values provided by the Aethalometer were significantly overestimated, eBC concentrations were corrected using an appropriate multiple-scattering enhancement correction factor (C0) to accurately calculate light absorption. Annual and seasonal variations highlighted the significant contributions of traffic emissions to eBC mass concentrations at all sites. Source apportionment using the Aethalometer approach demonstrated that fuel combustion—primarily from gasoline and diesel vehicles— accounted for up to 80% of eBC emissions. Emission sources were found to be largely region specific. Our findings suggest that the implementation of restrictive regulations aimed at reducing gasoline and diesel vehicle emissions, such as California's Tier 3 (SULEV, 2015) and New York (2017), has led to a higher proportion of cleaner, emission-controlled vehicles in the South Coast Air Basin compared to Rochester. However, the effects of these measures may require more time to be fully observed in traffic-polluted areas across the US.

Factors and circumstances affecting the business performance of firms based on new technologies

New technology-based firms (NTBFs) invent, develop, and commercialize original technologies whose research, development, and commercial success is highly uncertain and risky. Their growth is lengthy and often insufficient, but investors’ growth expectations are high. The study aims to determine factors and circumstances that affect the growth of new technology-based firms. The source of knowledge is a personal experience from a guided interview with the founder, which is recorded in the questionnaire. The research sample includes 67 NTBFs doing business in Slovakia. The respondents’ statements were analyzed using critical discourse analysis (CDA) with the support of artificial intelligence. The results are the factors that influence the business performance of the investigated companies. The performance of companies that show a long-term loss is affected by very limited access to financial resources, restrictive regulations, and a lack of qualified employees. The performance of companies that show a long-term profit is influenced by favorable access to external capital, effective management of human resources, optimization of internal processes, and improvement of marketing. The order of the identified factors expresses their importance in the thematic group. The secondary results are the accompanying circumstances of the growth of the investigated companies, namely the reasons for the establishment of NTBF and entry into business, commercialization of new technology, and cooperation with investors and banks. The combination of limited access to finance and a lack of qualified human resources creates a complex set of obstacles to the business performance of NTBFs. AcknowledgmentThis work was supported by the Scientific Grant Agency of the Ministry of Education of the Slovak Republic and Slovak Academy of Sciences (VEGA) under the grant “Accelerating the growth of innovative enterprises - scaling up scale-ups and new technology-based firms (NTBFs)”, number 1/0006/22.

PTPN14 aggravates neointimal hyperplasia via boosting PDGFRβ signaling in smooth muscle cells

Smooth muscle cell (SMC) phenotypic modulation, primarily driven by PDGFRβ signaling, is implicated in occlusive cardiovascular diseases. However, the promotive and restrictive regulation mechanism of PDGFRβ and the role of protein tyrosine phosphatase non-receptor type 14 (PTPN14) in neointimal hyperplasia remain unclear. Our study observes a marked upregulation of PTPN14 in SMCs during neointimal hyperplasia. PTPN14 overexpression exacerbates neointimal hyperplasia in a phosphatase activity-dependent manner, while SMC-specific deficiency of PTPN14 mitigates this process in mice. RNA-seq indicates that PTPN14 deficiency inhibits PDGFRβ signaling-induced SMC phenotypic modulation. Moreover, PTPN14 interacts with intracellular region of PDGFRβ and mediates its dephosphorylation on Y692 site. Phosphorylation of PDGFRβY692 negatively regulates PDGFRβ signaling activation. The levels of both PTPN14 and phospho-PDGFRβY692 are correlated with the degree of stenosis in human coronary arteries. Our findings suggest that PTPN14 serves as a critical modulator of SMCs, promoting neointimal hyperplasia. PDGFRβY692, dephosphorylated by PTPN14, acts as a self-inhibitory site for controlling PDGFRβ activation.

City Regionalism in the Global South: Evidence from Sub-Saharan Africa

This study investigates city regionalism within the context of state restructuring in postcolonial Ghana. To understand Ghana’s emerging city regionalism, first, we argue that planning is marshaled as an institutional instrument to materialize the state’s vision of remaking national territory and internationalizing the state. Second, city regionalism is a political process leveraged by a unique power geometry. The study adopts Ghana’s Northern Savannah Ecological Zone (NSEZ) regional plan to elucidate city regionalism in the Global South. Our findings reveal the central government’s inclination toward endogenous territorial restructuring, by which city region development is centrally orchestrated and state guided. In addition, city regionalism is influenced by the geostrategic ambitions of international capital, especially Chinese capital, which seeks to draw investment into the built environment and infrastructure. The central government’s customization of a regional governance agency, the Northern Development Authority (NDA), and the decentralization of land resources give rise to a “dumbbell” power structure. The concentration of legal and cohesive power in the central government and an overly privatized land ownership regime characterize this dumbbell power structure. The operation of the NDA is thus a scaffolding with no substantial power. The central government exercises restrictive fiscal regulation over regional and local states in the NSEZ. These two dimensions hamper the effective implementation of the regional plan. Collaboration between different levels of state administration, traditional authorities, and civil society actors is imperative to address the complexities of city regionalism in postcolonial Ghana.

Neutrophils Recruited by NKX2-1 Suppression via Activation of CXCLs/CXCR2 Axis Promote Lung Adenocarcinoma Progression.

NK2 Homeobox 1 (NKX2-1) is a well-characterized pathological marker that delineates lung adenocarcinoma (LUAD) progression. The advancement of LUAD is influenced by the immune tumor microenvironment through paracrine signaling. However, the involvement of NKX2-1 in modeling the tumor immune microenvironment is still unclear. Here, the downregulation of NKX2-1 is observed in high-grade LUAD. Meanwhile, single-cell RNA sequencing and Visium in situ capturing profiling revealed the recruitment and infiltration of neutrophils in orthotopic syngeneic tumors exhibiting strong cell-cell communication through the activation of CXCLs/CXCR2 signaling. The depletion of NKX2-1 triggered the expression and secretion of CXCL1, CXCL2, CXCL3, and CXCL5 in LUAD cells. Chemokine secretion is analyzed by chemokine array and validated by qRT-PCR. ATAC-seq revealed the restrictive regulation of NKX2-1 on the promoters of CXCL1, CXCL2, and CXCL5 genes. This phenomenon led to increased tumor growth, and conversely, tumor growth decreased when inhibited by the CXCR2 antagonist SB225002. This study unveils how NKX2-1 modulates the infiltration of tumor-promoting neutrophils by inhibiting CXCLs/CXCR2-dependent mechanisms. Hence, targeting CXCR2 in NKX2-1-low tumors is a potential antitumor therapy that may improve LUAD patient outcomes.

The impacts of policy restrictions on trade in services

ABSTRACT The objective of this paper is to estimate how different types of policy restrictions affect trade in services. We employ the Service Trade Restrictiveness Index (STRI) database and the International Trade in Services Statistics (ITSS) provided by the OECD to compile a sample encompassing 15 service sectors across 48 countries for the period from 2014 to 2018. The estimated results indicate that more restrictive regulations impede international service trade in terms of both the value of trade (intensive margin) and the probability of trade (extensive margin). We also find that the negative impact of policy restrictions on trade does not always increase with increasing restrictiveness. While moderate policy restrictions can facilitate international trade in services, stricter regulations impede it. Finally, the impact of policy regulations on service trade depends on the type and objective of restrictions. Regulations that are discriminatory or target foreign firms tend to reduce trade values, whereas non-discriminatory regulations related to policy transparency enhance service trade between countries.

End-Of-Life Cancer Patients' Dignity Perception Before and During COVID-19 Pandemic.

Background: The safety and restriction regulations implemented to contain the COVID-19 pandemic significantly impacted people's quality of life compromising the perception of dignity. Preserving dignity for end-of-life patients remains a paramount objective in palliative care. This study aimed to compare dignity levels in terminal cancer patients between pre- and during-pandemic periods. Methods: Dignity was assessed by the Italian version of the Patient Dignity Inventory (PDI-IT) in both pre- and during-pandemic groups of terminal cancer inpatients (hospitalized or admitted in hospice). The 2 groups were compared using non-parametric tests and a multivariate logistic regression analysis to estimate the association of the different dimensions of dignity with COVID-19 period, adjusting for other confounders. The study involved 2 groups of end-of-life cancer patients with a Karnofsky Performance Status (KPS) index less than 50. The first group included 506 patients before COVID-19, and the second group consisted of 156 patients enrolled during pandemic. Results: Existential Distress, Loss of Purpose and Meaning, Physical Symptoms and Dependency, Social Support PDI subscales and PDI Total score were higher in the during-pandemic group. The multivariate regression model partially supported the previous results as Loss of Purpose and Meaning, Social Support, and Existential Distress PDI subscales were associated with during-pandemic period, whereas PDI Physical Symptoms and Dependency and PDI Psychological Distress were not. Conclusion: Social isolation and other restrictions put in place to contain the COVID-19 pandemic may have had a negative impact on the perception of dignity in cancer patients at the end of life.

Analysis of the Effectiveness of Implementing Regulations Restricting Smartphone Use as an Effort to Handle Student Behavior

The use of smartphones in the STIBA Makassar environment has the potential to cause students to tend to behave deviantly, especially in aspects of the Shari'a and its practice. With concerns about this potential, regulations limiting the use of smartphones have been established as an Islamic social control so that guidance in the STIBA Makassar environment can run as expected and be able to direct students to maintain their behavior in life. This research was conducted with the aim of analyzing the effectiveness of regulations limiting the use of smartphones in controlling student behavior at STIBA Makassar. This research uses primary data through questionnaires and a quantitative approach through descriptive statistics techniques and difference tests (paired sample t-test). The results of the research show that, in general, there has been a decrease in the frequency of smartphone use for deviant behavior. This can also be seen in the increase in the frequency level of "Never", which means that more and more students never use smartphones for deviant behavior again after the regulation was implemented. Statistically, the implemented Smartphone Use Restriction Regulations have proven to be significantly successful and effective in dealing with student behavior at STIBA Makassar.

Human Behavior and Harvest Regulations: Challenges and Opportunities for Fisheries Managers

Harvest regulation is one of the primary tools that natural resource managers use to manage exploited fish and wildlife populations. Unfortunately, the desired results of harvest regulations are frequently not realized. We contend that a broader and more thorough understanding of anglers could improve the success of harvest regulations. Using a case study from an interstate U.S. fishery for Walleye Sander vitreus, we demonstrate the counterintuitive responses anglers exhibited to differing Walleye harvest regulations. Three possible reasons are explored, using theories from social–science disciplines, to explain why anglers released a greater proportion of larger Walleye under a more liberalized harvest regulation: (1) harvest regulations serving as goals for anglers, (2) resolution of cognitive dissonance provided by restrictive harvest regulations, and (3) the perceived “value” assigned to specific fish or wildlife entity by harvest regulations. We conclude by discussing how taking an interdisciplinary approach (e.g., sociology, psychology, economics) to understanding angler behavior could be an exciting frontier for fisheries management and how this approach specifically holds promise for improving the success of harvest regulations.

Feasibility and Application of Local Closed-Loop Materials to Produce Compressed and Stabilized Earth Blocks.

The validation of a feasible application for the production of sustainable bricks with local materials in humid and hot climates, which would allow the current housing needs of a constantly growing population with scarce economic resources to be met while also reducing energy inputs for climate control, is a current challenge without a definitive solution. Therefore, this research studied the incorporation of local aggregates and two second-generation materials to produce lime-stabilized Compressed Earth Blocks (CSEBs) using a semi-automatic machine for their manufacture. An initial matrix was designed as a baseline, and three more were developed with variations to incorporate second-generation materials individually and as mixtures. The stabilizer was added in concentrations of 5, 10, and 15%, resulting in a total of 12 batches of CSEBs. Eleven of the studied batches exceed the normative limits for simple compressive strength and initial water absorption coefficient. The best result of simple compressive strength was obtained in two batches of the same matrix that used construction demolition waste (CDW), reaching 4.3 MPa (43% above the minimum limit established by the most restrictive regulations and 115% above the least restrictive). It was possible to produce sustainable bricks in situ with average ambient temperatures of 32 °C and relative humidity of 91%.

P-759 Safety and quality of MAR (medically assisted reproduction) provisions in Spain in response to adaptative regulation during a public health emergency: a national registry analysis

Abstract Study question Did the level of quality and the safety of MAR treatments change in response to the restrictive medical care regulations during the COVID emergency? Summary answer All assessed markers of PMA treatment quality and safety were maintained, indicating a robust quality structure of the Spanish PMA medical system. What is known already Acute public health stressors can affect the provision of effective and safe care in specific healthcare areas, as operational constrains are put in place and resource allocation is shifted to emerging areas of need. During 2020, Spain was heavily affected by the COVID pandemic, and the provision of PMA was constrained both in time and scope for several months. Here, we examine the results of these constrains on the quality and safety of PMA treatments performed in the country through the comparative analysis of pre- and post- emergency national data. Study design, size, duration This retrospective study includes aggregate registry data from 316 PMA centers in Spain, representing 100% of reported IVF/ICSI treatments in the country. Data refer to treatments performed in 2019, 2020 and 2021.Treatment data were compared on an intention to treat basis (ITT) whenever possible. Participants/materials, setting, methods A total of 48.123, 40.453 and 49.734 IVF/ICSI treatments with own oocytes were initiated in 2019, 2020 and 2021 respectively. Oocyte donor stimulation were 15.807, 12.001, and 13.287, respectively. Safety markers analyzed were: oocytes collected (donation), multiple pregnancies and births, complications of treatment requiring hospitalization. Indicators of efficacy were pregnancy and live birth rates, with and without PGT-A, on an ITT basis. Data were compared by ANOVA or t-test. A p < 0.05 was considered significant. Main results and the role of chance The ratio between transfers and clinical results in IVF/ICSI cycles with own eggs, according to treatment intention, has remained stable in both pregnancies [34.4-34.8%] and deliveries [24.7-25.7%] between 2019, 2020 and 2021 Births with multiple fetuses were 11.3%, 9.4% and 8.7% respectively. Live births from PGT-A cycles were 22.4% in 2019 and 23.0% in 2020. The results of cycles with donor eggs remained stable in both pregnancies [56.7-58.7%] and deliveries [43.3-44.2%] between 2019, 2020 and 2021. Births with multiple fetuses were 10.7%, 9.8% and 8.2% respectively. Births of higher order than twins were anecdotal. Complications requiring hospital admission have remained at 0.20% - 0.026% of total treatments, with ovarian hyperstimulation and hemorrhages being the most frequent. Limitations, reasons for caution The aggregate nature of data did not allow for a more in depth associative analysis. Wider implications of the findings The analyzed indicators have remained within the expected ranges, suggesting a low impact of the COVID measures on the operational quality and safety of the TRA units. Trial registration number NA

Infant and children's exposure to food additives: An assessment of a comprehensive packaged food database

This study aimed to analyze the exposure of Brazilian infants and children to food additives through a comprehensive packaged food labelling database. Data collection was conducted at a large retail chain supermarket store in 2020 collecting the food labelling information from 7828 packaged foods. In total, 1118 packaged foods targeted at infants and children divided in 39 food groups were analyzed to investigate the presence, number, type and functional class of food additives declared in the ingredient list. Of these, 86 % declared at least one type of food additive. The average number of food additives in a single food was 4, with a maximum of 20 additives. In 17 food groups, there were no additive-free options. The most common additive functional classes were flavorings (70.7 %), emulsifiers (43.6 %), and color agents (33.8 %). These same functional classes most frequently co-occurred with other classes. These results suggest an important exposure of Brazilian children to food additives, and the situation is little analyzed in other countries. Therefore, it is urgent to identify this issue around the world, as well that food regulatory agencies should consider more restrictive regulations on the use of additives in packaged foods targeted at infants and children.

Developing China's Approaches to Regulate Cross-border Data Transfer:Relaxation and Integration

This article illustrates the developing Chinese cross-border data flow regulation regime deriving from a holistic national security conception to its balance with personal information protection and digital economic development. Under the pressuring demand of digital economy development and an increasing appeal to global data governance, China is progressively improving and modifying its original government-led and restrictive cross-border data regulations. Subsequent practices and the publication of the Provisions on Promoting and Regulating Cross-border Data Transfer (PPR) in March 2024 deliver a clear sign of relaxation on restrictions on cross-border data flow, especially on the subject of personal information outbound transfer. Detailed comparison with data provisions in the Regional Comprehensive Economic Partnership (RCEP), the Comprehensive and Progressive Agreement for Trans-Pacific Partnership (CPTPP), and the Digital Economy Partnership Agreement (DEPA) demonstrates that global governance of cross-border data flows is unshaped but not unrealistic, even with current fragmented national approaches. China has established a complete personal information protection legal regime and is very close to integrating into transnational cooperation for a broader framework. In addition, by coordinating national provisions regarding cross-data transfer with international rules and piloting lenient cross-border data supervision mechanisms in numerous Pilot Free Trade Zone (PFTZ), China is ready to evolve its cross-border data flow regulations and contribute to global data governance step-by-step.

Recreational angler preferences for, and potential effort responses to, different red snapper management approaches

AbstractThe Gulf of Mexico red snapper fishery has been caught in a spiral of more restrictive regulations and disputed management. Current management measures have failed to reduce fishing mortality, owing in part to derby style fishing. A harvest tag system could potentially better limit fishing mortality without decreasing harvest seasons. In 2019/20 we surveyed 766 recreational anglers who fish in Florida with private boats to ascertain their preferences for regulation changes, and how they would alter their fishing effort if a harvest tag was implemented. Respondents were heterogeneous in terms of their preferences for harvest tags versus current management approaches, with most respondents preferring to maintain their current effort under the existing management approach of bag, size, and season limits. Respondents who preferred harvest tags indicated that they might increase or decrease fishing effort. Our findings suggest that more stringent regulations using current management approaches will not secure angler satisfaction or reduce fishing pressure on the red snapper stock. Harvest tags, though not preferred by all respondents, may allow regulators to better manage the number of anglers in the fishery and to rebuild the stock, although implementing this program will pose some challenges.

Minimising unnecessary restrictions on cross-border data flows? Indonesia’s position and challenges post personal data protection act enactment

ABSTRACT In the era of massive digital development, data plays an essential role as a ‘fuel’ in reshaping and creating new opportunities in the digital landscape, especially in the digital economy. The significance of data for Indonesia can be seen from the amount of data created, collected, and analysed in various sectors. However, Indonesia also faces problems of data breaches that happened in recent years, which harm society and need immediate attention. This article examined Indonesia’s data and cross-border data flow regulatory and institutional frameworks and its implementation challenges, especially with the recent enactment of a comprehensive Personal Data Protection Act (PDP Act), mainly inspired by the EU GDPR. This article shows that Indonesia is moving to less restrictive data-flow regulations than the previous regulatory regime but is still between the prescriptive and restrictive spectrum of data-flow regulation. This article argues that the enactment of the PDP Act can be momentum for Indonesia to evaluate the current regulatory framework to ensure that Indonesia’s regulation is not providing unnecessary restrictions that lead to complexity of implementation and will hinder from benefiting the utilisation of data.