Restorative Treatment Research Articles

Integrating Earth observation, biophysical, and survey data to evaluate the ecological impacts of a common land protection and restoration intervention in Rajasthan, India

Integrating Earth observation, biophysical, and survey data to evaluate the ecological impacts of a common land protection and restoration intervention in Rajasthan, India

Effectiveness of bioactive resin materials in preventing secondary caries and retention loss in direct posterior restorations: A systematic review and meta-analysis.

This systematic review aimed to determine whether bioactive resin materials can prevent secondary caries or enhance the longevity of direct posterior restorations. The protocol was registered in PROSPERO (CRD42024561179). The review followed PRISMA guidelines, utilizing a PICO framework. Studies were identified through searches in six databases (PubMed, Scopus, Cochrane, Embase, Scielo, Web of Science) up to May 2024. Two independent reviewers applied inclusion criteria, selecting randomized clinical trials evaluating bioactive resin composites in restorative dentistry. Data were extracted into pre-designed forms, and article quality was assessed using the CONSORT, RoB 2, and GRADE tools. Meta-analyses focused on secondary caries incidence and restoration longevity using USPHS and FDI criteria. Of 1,565 articles identified, 10 met the inclusion criteria. These studies, conducted in five countries, included 411 participants with follow-up periods ranging from 1 to 8 years. Materials evaluated included ACTIVA™ BioACTIVE, Giomer, and Cention N. Meta-analysis found no statistically significant differences between bioactive and conventional resin composites in preventing secondary caries or reducing retention loss (p > 0.05), the two primary outcomes considered in this review for assessing restoration longevity. Subgroup analysis showed no differences between follow-up periods. Bioactive materials demonstrated similar clinical performance to conventional composites in preventing secondary caries and retaining restorations, offering no additional benefit in enhancing the longevity of direct posterior restorations. This review provides evidence that bioactive resin materials offer no significant clinical advantage over traditional composites, guiding (or informing) clinicians in (or about) material selection for restorative treatments.

Transplanted deep-layer cortical neuroblasts integrate into host neural circuits and alleviate motor defects in hypoxic-ischemic encephalopathy injured mice.

Hypoxic-ischemic encephalopathy (HIE) is a major cause of neonatal disability and mortality. Although intensive studies and therapeutic approaches, there are limited restorative treatments till now. Human embryonic stem cell (hESCs)-derived cortical neural progenitors have shown great potentials in ischemic stroke in adult brain. However, it is unclear whether they are feasible for cortical reconstruction in immature brain with hypoxic-ischemic encephalopathy. By using embryonic body (EB) neural differentiation method combined with DAPT pre-treatment and quantitative cell transplantation, human cortical neuroblasts were obtained and transplanted into the cortex of hypoxic-ischemic injured brain with different dosages 2 weeks after surgery. Then, immunostaining, whole-cell patch clamp recordings and behavioral testing were applied to explore the graft survival and proliferation, fate commitment of cortical neuroblasts in vitro, neural circuit reconstruction and the therapeutic effects of cortical neuroblasts in HIE brain. Transplantation of human cortical neural progenitor cells (hCNPs) in HIE-injured cortex exhibited long-term graft overgrowth. DAPT pre-treatment successfully synchronized hCNPs from different developmental stages (day 17, day 21, day 28) to deep layer cortical neuroblasts which survived well in HIE injured brain and greatly prevented graft overgrowth after transplantation. Importantly, the cortical neuroblasts primarily differentiated into deep-layer cortical neurons and extended long axons to their projection targets, such as the cortex, striatum, thalamus, and internal capsule in both ipsilateral and contralateral HIE-injured brain. The transplanted cortical neurons established synapses with host cortical neurons and exhibited spontaneous excitatory or inhibitory post-synaptic currents (sEPSCs or sIPSCs) five months post-transplantation. Rotarod and open field tests showed greatly improved animal behavior by intra-cortex transplantation of deep layer cortical neuroblasts in HIE injured brain. Transplanted hESCs derived cortical neuroblasts survive, project to endogenous targets, and integrate into host cortical neural circuits to rescue animal behavior in the HIE-injured brain without graft overgrowth, providing a novel and safe cell replacement strategy for the future treatment of HIE.

A Systematic Review Evaluating Methods for Diagnosis, Treatment and Prevention of Dental Erosions.

The aim of this systematic review was to investigate the quality of evidence for methods used to diagnose, restore and prevent dental erosions, by evaluating and summarising clinical controlled studies and insitu studies covering this field. Three databases, PubMed, Embase and Cochrane database, were searched for studies published until October 2023. Studies fulfilling the selection criteria were selected, and the risk of bias of the included studies was assessed. Two authors independently reviewed the studies, evaluated their risk of bias and extracted data from the included studies. The certainty of evidence of the findings in the studies was determined using GRADE. The literature search identified 7176 records. Out of these, 19 studies were included in this review, three revolving diagnostics, three revolving treatment and 13 revolving prevention. However, due to the fact that only few studies with a small number of participants have investigated the same methods on the same outcome, the studies do not constitute any body of evidence. This systematic review highlights the shortage of data on methods used for diagnostics, restorative treatment and prevention of dental erosions. More knowledge is needed to strengthen the scientific evidence regarding methods used for dental erosions.

Use of magnetic sheets in vertical deformation treatment of textile supports of contemporary paintings

The practice developed during a conservation and restoration intervention does not always follow common or traditional standards, whether due to technical limitations, or space constraints related to the size of the works, or by the material requirements that the works themselves can present. In the light of various particularities and needs, research was initiated into the use of harmless and satisfactory methods in the occasional treatment of deformations of the support of contemporary pictorial works, using magnetic sheets. In its use, different valences were evaluated, such as the control in the iteration of the work, the effectiveness and control of humidity and time during the performance of the treatments, and the results obtained. This article will reflect on the process developed with the application of four case studies, presenting the advantages and disadvantages in the use of this method.

Enhancing pediatric comfort: a comprehensive approach to managing molar-incisor hypomineralization with preemptive analgesia and behavioral strategies.

Preemptive analgesia is an important strategy used in pediatric dentistry to intercept pain signals in neural pathways early, thus mitigating the perception of pain and enhancing overall patient comfort. Pedodontists often encounter challenges in conducting the therapy and managing uncooperative patients, when addressing enamel defects of the Molar-incisor hypomineralization (MIH) type. The aim of this study is to demonstrate the impact of preemptive analgesia on optimizing behavioral management and restorative treatment strategies for immature permanent molars exhibiting severe MIH and Treatment need index 4 (TNI), through the effective control of pain. This study comprised 27 cases with MIH level 3 Posteruptive breakdown (PEB), indicating post-eruptive enamel breakdown, with initial hypersensitivity scores exceeding 4 on the Wong-Baker Scale, was conducted over 12 months, between January 2023-January 2024. Data on pediatric patients aged between 5 years and 4 months and 7 years and 1 month with varying degrees of sensitivity in their permanent first molars before the completion of the eruption process were collected. Pain intensity was systematically evaluated at six specific time points: before and after the administration of analgesic medication as well as during restorative treatment using the Wong-Baker scale and data from the Face, Legs, Activity, Cry, Consolability index (FLACC). Statistical analysis for Wong-Baker scores and FLACC index indicated statistical significance (p < 0.05) for Mann-Whitney and Wilcoxon tests, respectively t-test. The comparison of mean scores recorded before and after preemptive analgesia during rotary instrumentation moments for the Wong-Baker index (4 > 0.29) and for the FLACC index (8.47 > 1.71) indicates the positive influence of administering ibuprofen. In conclusion, preemptive analgesia, alongside standardized anesthesia, significantly improved intraoperative pain management and behavioral outcomes.

Metagenomic Insights into Coal Slag Remediation Effects on Soil and Microbial Health in Qinghai’s Muli Coal Mine

Long-term coal mining in the Muli coal mine area of Qinghai Province has degraded soil quality and reduced microbial diversity, making it imperative to implement effective ecological restoration measures to restore soil quality and enhance ecosystem functions. This study evaluated soil samples under 11 ecological restoration treatments using metagenomic sequencing combined with soil quality analysis to explore the responses of the microbial community structure and function to identify effective restoration measures. This study demonstrated that ecological restoration significantly increased the soil microbial diversity and richness, with the MLII1 (soil samples treated with a chemical weathering agent, attapulgite, and a microbial agent) and MLIII1 (soil samples treated with sheep manure (2.4 kg/m2), granular organic fertilizer (1.2 kg/m2), and the microbial agent) treatment groups performing exceptionally well. Further analysis of the functional networks revealed that although the MLII2 (soil samples treated with the chemical weathering agent and attapulgite) treatment group did not exhibit the highest species diversity, it exhibited the highest functional network complexity. The results of hierarchical clustering analysis showed that the microbial community of the MLII2 treatment group was most similar to that of the natural meadows compared to the other treatment groups. From the perspective of overall ecological restoration, this study concluded that the MLII2 treatment group exhibited the most favorable ecological restoration outcomes. This finding emphasizes the importance of not only enhancing microbial diversity but also prioritizing the restoration of community functions, especially for the recovery of fragile high-altitude ecosystems.

MMP Inhibition, Marginal Integrity and Cytotoxicity of Zinc-Releasing GIC

ObjectivesThe degradation of the restorative-dentin interface due to endogenous dentin enzymes, such as matrix metalloproteinases (MMPs), is a significant issue that accelerates the deterioration of the dentin matrix and leads to the failure of restorative treatments. Caredyne Restore (CR), a novel glass ionomer cement (GIC) with zinc ions in its formulation, represents the latest effort to mitigate this issue. This investigation aimed to evaluate the MMPs inhibitory effect, marginal integrity, and cytotoxicity of CR compared to a conventional GIC, Fuji IX (FIX). MethodsThe inhibitory effect of CR on MMPs activity was evaluated using in-situ zymography to visualize the endogenous gelatinolytic activity in the GIC-dentin interface. Additionally, CR's sealing properties were investigated using dye-assisted confocal laser microscopy (CLSM) to assess marginal leakage across the GIC-dentin interface. Both in-situ zymography and CLSM observations were conducted 1 day and seven days after pH cycling. Finally, the cytotoxicity of the GIC eluates was examined on rat dental pulp cells (RPC-C2A). Assay measurements were performed after 24 and 48 h of incubation with test solutions prepared using various GIC eluate concentrations. ResultsThe MMPs activity of the CR specimens was significantly lower than that of FIX specimens after seven days of pH cycling. Signs of marginal leakage were also lower in the CR specimens. Comparison of CR and FIX eluates at the same concentration showed no significant difference in terms of biocompatibility. ConclusionsCaredyne restore is capable of inhibiting endogenous enzyme activity and improving sealing properties, while maintaining sufficient biocompatibility. Clinical SignificanceZinc ions released from Caredyne Restore offer a safe way to improve the quality of dental restorations and promote minimally invasive treatment, especially in lesions where the dentin matrix is susceptible to enzymatic degradation and recurrent caries.

Iron Chelators Augment Large Osteochondral Allograft Osseointegration in a Preclinical Canine Model.

Osteochondral allograft transplantation (OCAT) can be a successful joint restoration treatment option for large post-traumatic articular defects but is still associated with significant revision and failure rates. Despite recent advances that have improved OCAT success, insufficient osteochondral allograft (OCA) osseointegration remains a major cause of failure. Deferoxamine (DFO) is an effective angiogenic and osteo-anabolic iron chelator that consistently promotes bone neovascularization and regeneration. This study was designed to investigate local delivery of DFO for augmenting OCA osseointegration using a preclinical canine model for OCAT in the knee and hip as commonly affected joints. On Institutional Animal Care and Use Committee (IACUC) approval, 12 purpose-bred dogs underwent OCAT of the femoral head or femoral condyles with DFO or DFO-free (controls) microspheres in recipient sites. OCA revascularization, cellular repopulation, and integration were evaluated based on functional, diagnostic imaging, microcomputed tomography, histology, and immunohistochemistry outcome measures. Local delivery of DFO into OCAT recipient sites was associated with maintained or improved joint function, superior radiographic appearance, significantly greater trabecular thickness, higher bone volume, and new bone ingrowth compared with DFO-free controls. OCA osseointegration is dependent on cellular repopulation and neovascularization, resulting in new bone ingrowth through creeping substitution, and insufficient osseointegration with resorption and subsidence of the OCA remains a major cause of failure after transplantation. The results of this study suggest that local delivery of DFO using a controlled microsphere release system may reduce resorption and improve revascularization and cellular repopulation to increase new bone ingrowth, potentially expediting OCA osseointegration after transplantation.

Restorative Treatments for Cervical Spinal Cord Injury, a Narrative Review.

A narrative review. To summarize relevant data from representative studies investigating upper limb restorative therapies for cervical spinal cord injury. Cervical spinal cord injury (SCI) is a debilitating condition resulting in tetraplegia, lifelong disability, and reduced quality of life. Given the dependence of all activities on hand function, patients with tetraplegia rank regaining hand function as one of their highest priorities. Recovery from cervical SCI is heterogeneous and often incomplete; currently, various novel therapies are under investigation to improve neurological function and eventually better quality of life in patients with tetraplegia. In this article, a narrative literature review was performed to identify treatment options targeting the restoration of function in patients with cervical SCI. Studies were included from available literature based on the availability of clinical data and whether they are applicable to restoration of arm and hand function in patients with cervical SCI. We describe relevant studies including indications and outcomes with a focus on arm and hand function. Different treatment modalities described include nerve transfers, tendon transfers, spinal cord stimulation, functional electrical stimulation, non-invasive brain stimulation, brain-machine interfaces and neuroprosthetics, stem cell therapy, and immunotherapy. As the authors' institution leads one of the largest clinical trials on nerve transfers for cervical SCI, we also describe how patients undergoing nerve transfers are managed and followed at our center. While complete recovery from cervical spinal cord injury may not be possible, novel therapies aimed at the restoration of upper limb motor function have made significant progress toward the realization of complete recovery.

Human Health Adaptation Strategies to Climate-Induced Extreme Weather Events: A Systematic Review

This systematic review evaluates the health impacts of climate-induced extreme weather events and the effectiveness of various adaptation strategies. Seventeen studies were analyzed, focusing on adaptation measures such as agricultural adjustments, renewable energy, ecosystem restoration, infrastructure redesign, and public health interventions. Significant health impacts were identified, including increased morbidity and mortality due to heatwaves, floods, and vector-borne diseases. The success of adaptation strategies was found to be highly dependent on local context, implementation capacity, and sustainability. This review underscores gaps in data quality, the generalizability of findings, and the integration of adaptation measures into public health policies. An urgent need exists for interdisciplinary approaches and community engagement to ensure sustainable, equitable health outcomes in the face of climate change. Future research should focus on these areas to strengthen public health resilience.

Molar Incisor Hypomineralization: Etiology, Correlation with Tooth Number Anomalies and Implications for Comprehensive Management Strategies in Children from Transylvania.

This study investigates the etiology of enamel developmental defects, specifically Molar Incisor Hypomineralization (MIH), and explores correlations between MIH and dental anomalies such as hypodontia to improve interdisciplinary restorative and orthodontic treatments. Additionally, it assesses the influence of stress factors on the development of enamel defects. Conducted from July to September 2024, this study involved 57 patients aged 6 to 11 from an urban setting, divided into two groups: 32 with MIH and 25 controls, selected based on criteria of mixed dentition without systemic pathology or chronic medication. Clinical evaluations, including intraoral photographs and panoramic radiographs, were performed alongside a detailed questionnaire addressed to the mothers covering prenatal, perinatal, and postnatal factors. The average age of children with MIH was 7.5 years, in contrast to 7.04 years in the control group (p = 0.17). Significant differences were noted in maternal age, with MIH mothers older (35.56 years) than controls (29.36, p = 0.0001). The prevalence of MIH was higher in boys (66.7%) compared to girls (38.1%, p = 0.036). Factors such as prolonged labor, medication during birth, and early postnatal medication were significantly linked to MIH. The study shows a strong correlation with hypodontia, with a significantly higher incidence of tooth number anomalies (p = 0.009) in the study group. Overall, the study emphasizes the association of MIH with various maternal and birth-related factors and with hypodontia, highlighting the need for a comprehensive, multidisciplinary approach to diagnosis and treatment. Further research is recommended to investigate the relationship between stress factors and MIH.

Bibliometric Analysis of Platelet-Rich Plasma Treatment for Hair Restoration, Facial Rejuvenation, Dental Procedures, and Gynecological Rejuvenation

Introduction: Autologous platelet-rich plasma (PRP) technologies offer an attractive treatment option for various medical fields. Owing to its high concentration of growth factors, PRP has been posited to induce proliferation, differentiation, and angiogenesis at the cellular level, as well as wound-healing and remodeling at the tissue level. The goal of the present bibliometric analysis was to characterize the growing body of literature concerning PRP use in various medical applications. Methods: A comprehensive literature search was performed on June 28, 2024, using Web of Science and SCOPUS databases, covering all available publications in selected categories from 2001 to present. Results: PRP use for hair restoration had both the greatest number of total publications among the investigated applications, whereas PRP use in dental procedures had the longest-standing history of publications. PRP use in hair restoration and facial rejuvenation had the greatest number of placebo-controlled and double-blinded randomized controlled trials; however, the impact of results may suffer from a lack of consistency in PRP preparation and outcome measurement between different studies. Conclusion: To effectively validate the utility of PRP across various medical interventions, careful consideration of methodology should be undertaken for future studies to ensure validity of results.

A differentiated approach to the surgical treatment of intraarticular fracture of the proximal tibia

Background. For a long time, the question of optimal ways and methods of surgical treatment of fractures of the proximal part of the tibia (PPT) remains debatable. The purpose was to study the results of surgical treatment of fractures of the PPT using differentiated use of minimally invasive techniques. Materials and methods. The work consisted of a prospective analysis of the treatment outcomes of 87 patients who were treated 2018 to 2023. Fractures were classified according to Schatzker. The tactics of surgical treatment depended on the type of fracture, the age of the patients and the presence of concomitant diseases. A comprehensive assessment of knee function was performed using the Knee Society Score. For X-ray assessment of the degree of progression of post-traumatic arthritis, the Resnik/Niwoyama system was used. ­Results. The results of surgical treatment were studied in terms from 6 to 24 months. 19.8 % of excellent, 57.5 % good, 15.6 % sa­tisfactory and 7.1 % unsatisfactory treatment results were obtained. Progression of post-traumatic arthritis was observed in 36 patients (28 patients at one stage, 4 subjects at 2 stages and 5 patients at 3 stages). Of the complications, 7 (8.0 %) were surgical site infections, which required debridement of the focus and longer antibiotic therapy. Over time, loss of reposition and secondary displacement were identified in 5 (5.7 %) cases. The most common complications were the progression of knee osteoarthritis, the development of contractures in 11 (12.6 %) patients. Conclusions. The use of a differential approach to the surgical treatment of intra-articular fractures of PPT, based on the severity of injuries according to Schatzker, allowed to obtain positive functional results in 77.3 % of the victims. The negative consequences of intra-articular fractures of the tibial plateau that worsen the functional outcomes of treatment include the progression of knee osteoarthritis. The degree of its manifestations is largely determined by the severity of the injury, the quality of reduction, the stability of fragment fixation, and the rationality of restorative treatment and rehabilitation.

Impact of Dental Treatment Simulation App on Anxiety of Pediatric Dental Patients: An Observational Study

ABSTRACT Aim: The study aimed to investigate the effect of a dental treatment simulation app on the anxiety levels of pediatric dental patients. Materials and Methods: Forty children, aged 4–8 years and with no prior dental experience, were randomly assigned to either the control group (group I) or the dental app group (group II). The children’s anxiety levels were measured before and after undergoing restorative dental treatment, using the Chota Bheem Chutki pictorial scale. Results: The initial anxiety levels were similar across both groups. Post treatment, the dental app group exhibited a significant reduction in anxiety compared to the control group. This suggests that the simulation app has a beneficial effect in lowering dental anxiety in children. Conclusion: The dental treatment simulation app can effectively reduce pre and postoperative anxiety in pediatric patients, potentially enhancing their overall dental experience.

High-intensity pulse magnetic therapy and drinking mineral water in rehabilitation treatment of patients with chronic pancreatitis at inpatient stage

BACKGROUND: Sanogenetic effects of physical factors, providing restoration of disturbed functions of the organism, are the basis for their inclusion in the standardised programme of restorative treatment of patients with chronic pancreatitis. AIM: To study the effectiveness of high-intensity pulse magnetic therapy and low-mineralized drinking mineral waters in the restorative treatment of patients with chronic pancreatitis at the inpatient stage. MATERIALS AND METHODS: There has been carried out an open-label, randomized, controlled, prospective study of 125 patients with chronic pancreatitis. The patients were divided into 3 groups using the simple randomization method. In the control group (n=40) the patients underwent restorative treatment in accordance with federal clinical guidelines; in the group of comparison (n=42) he patients were additionally prescribed low-mineralized drinking mineral water; in the main group (n=43) the patients had high-intensity pulse magnetic therapy in addition to the treatment of the group of comparison. The effectiveness of rehabilitation measures was monitored using a visual analogue scale, a carbolene test, a hospital scale of anxiety and depression. RESULTS: The statistical analysis showed that the inclusion of drinking mineral water and high-intensity pulse magnetic therapy contributed to a significant reduction of pain (p 0.01) and dyspeptic syndromes (p 0.01), an improvement in motor evacuation function of intestine (p 0.01), a decrease in enzymatic activity and the severity of anxiety-depressive manifestations (p 0.01). The effectiveness of the developed programmes of restorative treatment of the patients suffering from chronic pancreatitis was 87.8–92.5%, the standardized programme ― 78.5%. CONCLUSION: The inclusion of drinking mineral waters and high-intensity pulse magnetic therapy in the standardized program of restorative treatment of the patients suffering from chronic pancreatitis at the inpatient stage provides a significant restoration of pancreatic external secretory function.

Leveraging extensive soil, vegetation, fire, and land treatment data to inform restoration across the sagebrush biome

ContextWidespread ecological degradation has prompted calls for massive global investments in ecological restoration, yet limited resources necessitate efficient application of restoration efforts. In western North America, altered fire regimes are increasing the scale of restoration needed to preserve the sagebrush (Artemisia species) biome but prioritizing and implementing effective restoration is complicated by the vast and heterogeneous sagebrush landscape, which includes gradients in climate, disturbance, and species composition.ObjectivesTo develop spatially explicit and context-dependent estimates of treatment efficacy and sagebrush recovery rates.MethodsWe leveraged a suite of spatio-temporally extensive datasets to evaluate the influence of restoration treatments and environmental conditions on trends in post-disturbance sagebrush cover, with an emphasis on understanding differences between sites recovering naturally and sites receiving restoration treatments. We used estimates from these models to develop spatially explicit projections for sagebrush recovery, conditional on disturbance, restoration practice, and environmental conditions.ResultsWe found seeding Artemisia spp. increased sagebrush cover over time relative to natural recovery, but this relationship depended on spring soil moisture availability and treatment methods. Natural recovery was positively influenced by soil moisture and sagebrush cover and negatively influenced by cumulative burns and annual herbaceous cover, while the influence of perennial herbaceous cover varied with soil moisture.ConclusionsOur results provide biome-wide insights and spatially explicit tools that can inform economic cost-effectiveness analyses, restoration prioritization tools, and other scientific endeavors to ensure managers have the tools and information needed to effectively steward the sagebrush biome in a rapidly changing world.

Anxiolytic Effect of Jasmine Aromatherapy in Pediatric Dental Procedures: A Single-Blinded Randomized Placebo-Controlled Trial

Objectives: The aim of the present investigation was to evaluate the possible anxiolytic effect of jasmine aromatherapy in pediatric dental procedures. Materials and Methods: A parallel randomized single-blinded placebo-controlled clinical trial was designed and conducted from February 19 until April 19, 2020, on children aged 7 to 12 years-old requiring class 1 restorative treatment of primary or permanent tooth with infiltration anesthesia. Interventions were defined as 15 minutes of aromatherapy using 2mL of jasmine extract for the intervention group, and with water for the control group. Outcomes were defined as child’s anxiety and pain perception, measured by modified child dental anxiety scale (MCDAS), visual analogue scale (VAS) and changes of vital signs. After the patients received interventions based on their groups, their data was collected and analyzed. We used parametric tests and linear regression for outcome comparisons. Results: 56 patients were randomized and allocated in two groups, 28 to each. The groups did not differ significantly regarding age, sex, heart rate and O2 saturation before, during, and after procedures. Based on multivariable regression, the intervention group showed a significantly reduced MCDAS (B (95% CI)=-2.11 (-4.09, -0.13), P=0.04) and VAS (B (95% CI)=-2.30 (-3.50, -1.10), P&lt;0.001) scores. Conclusion: Jasmine aromatherapy showed to be effective in reducing children’s anxiety and pain perception during dental procedures and therefore, can be suggested as a cheap and practical complementary method in dental practice.

МЕЗО-ФОРТЕ ТЕРАПИЯ В НЕЙРОРЕАБИЛИТАЦИИ ДЕТЕЙ С МИОПИЕЙ — ПИЛОТНОЕ ИССЛЕДОВАНИЕ

This article presents the results of a pilot clinical and experimental study of the prospects for neurorehabilitation of children with myopia using Meso-Forte Therapy (MFT), an innovative hardware method of restorative treatment using digital music therapy programs. For the first time, data from complex psycho physiological and ophthalmological studies is published, revealing the mechanisms of corrective regulation of the psycho emotional status, the autonomic nervous system, and the tone of the accommodating muscles of the eye using the main algorithms of musical and acoustic effects.

Projeto de extensão: resgatando sorrisos

The article addresses restorative and aesthetic dentistry, highlighting the importance of adhesion of materials to mineralized dental tissues. The philosophy of minimally invasive restorative treatment is based on principles of prevention and maximum preservation, with minimal intervention in dental structures. Dental aesthetics are subjective, influenced by several factors, and despite advances in aesthetic materials, the need for clinical evaluations on the behavior of composite resin restorations is increasing. In the Brazilian context, where the provision of government dental treatment is limited, perceived need becomes an important predictor of the use of dental services. There is a significant demand for restorative dentistry procedures, often performed by undergraduate and postgraduate students. The article highlights the creation of an Orthodontics Extension Project to deal with repressed demand, although new activities are necessary. It is concluded that initiatives such as extension projects are essential to mitigate the lack of care for the population and prepare academics for clinical practices in restorative dentistry.