Restorative Treatment Research Articles

Metagenomic Insights into Coal Slag Remediation Effects on Soil and Microbial Health in Qinghai’s Muli Coal Mine

Long-term coal mining in the Muli coal mine area of Qinghai Province has degraded soil quality and reduced microbial diversity, making it imperative to implement effective ecological restoration measures to restore soil quality and enhance ecosystem functions. This study evaluated soil samples under 11 ecological restoration treatments using metagenomic sequencing combined with soil quality analysis to explore the responses of the microbial community structure and function to identify effective restoration measures. This study demonstrated that ecological restoration significantly increased the soil microbial diversity and richness, with the MLII1 (soil samples treated with a chemical weathering agent, attapulgite, and a microbial agent) and MLIII1 (soil samples treated with sheep manure (2.4 kg/m2), granular organic fertilizer (1.2 kg/m2), and the microbial agent) treatment groups performing exceptionally well. Further analysis of the functional networks revealed that although the MLII2 (soil samples treated with the chemical weathering agent and attapulgite) treatment group did not exhibit the highest species diversity, it exhibited the highest functional network complexity. The results of hierarchical clustering analysis showed that the microbial community of the MLII2 treatment group was most similar to that of the natural meadows compared to the other treatment groups. From the perspective of overall ecological restoration, this study concluded that the MLII2 treatment group exhibited the most favorable ecological restoration outcomes. This finding emphasizes the importance of not only enhancing microbial diversity but also prioritizing the restoration of community functions, especially for the recovery of fragile high-altitude ecosystems.

MMP Inhibition, Marginal Integrity and Cytotoxicity of Zinc-Releasing GIC

ObjectivesThe degradation of the restorative-dentin interface due to endogenous dentin enzymes, such as matrix metalloproteinases (MMPs), is a significant issue that accelerates the deterioration of the dentin matrix and leads to the failure of restorative treatments. Caredyne Restore (CR), a novel glass ionomer cement (GIC) with zinc ions in its formulation, represents the latest effort to mitigate this issue. This investigation aimed to evaluate the MMPs inhibitory effect, marginal integrity, and cytotoxicity of CR compared to a conventional GIC, Fuji IX (FIX). MethodsThe inhibitory effect of CR on MMPs activity was evaluated using in-situ zymography to visualize the endogenous gelatinolytic activity in the GIC-dentin interface. Additionally, CR's sealing properties were investigated using dye-assisted confocal laser microscopy (CLSM) to assess marginal leakage across the GIC-dentin interface. Both in-situ zymography and CLSM observations were conducted 1 day and seven days after pH cycling. Finally, the cytotoxicity of the GIC eluates was examined on rat dental pulp cells (RPC-C2A). Assay measurements were performed after 24 and 48 h of incubation with test solutions prepared using various GIC eluate concentrations. ResultsThe MMPs activity of the CR specimens was significantly lower than that of FIX specimens after seven days of pH cycling. Signs of marginal leakage were also lower in the CR specimens. Comparison of CR and FIX eluates at the same concentration showed no significant difference in terms of biocompatibility. ConclusionsCaredyne restore is capable of inhibiting endogenous enzyme activity and improving sealing properties, while maintaining sufficient biocompatibility. Clinical SignificanceZinc ions released from Caredyne Restore offer a safe way to improve the quality of dental restorations and promote minimally invasive treatment, especially in lesions where the dentin matrix is susceptible to enzymatic degradation and recurrent caries.

Iron Chelators Augment Large Osteochondral Allograft Osseointegration in a Preclinical Canine Model.

Osteochondral allograft transplantation (OCAT) can be a successful joint restoration treatment option for large post-traumatic articular defects but is still associated with significant revision and failure rates. Despite recent advances that have improved OCAT success, insufficient osteochondral allograft (OCA) osseointegration remains a major cause of failure. Deferoxamine (DFO) is an effective angiogenic and osteo-anabolic iron chelator that consistently promotes bone neovascularization and regeneration. This study was designed to investigate local delivery of DFO for augmenting OCA osseointegration using a preclinical canine model for OCAT in the knee and hip as commonly affected joints. On Institutional Animal Care and Use Committee (IACUC) approval, 12 purpose-bred dogs underwent OCAT of the femoral head or femoral condyles with DFO or DFO-free (controls) microspheres in recipient sites. OCA revascularization, cellular repopulation, and integration were evaluated based on functional, diagnostic imaging, microcomputed tomography, histology, and immunohistochemistry outcome measures. Local delivery of DFO into OCAT recipient sites was associated with maintained or improved joint function, superior radiographic appearance, significantly greater trabecular thickness, higher bone volume, and new bone ingrowth compared with DFO-free controls. OCA osseointegration is dependent on cellular repopulation and neovascularization, resulting in new bone ingrowth through creeping substitution, and insufficient osseointegration with resorption and subsidence of the OCA remains a major cause of failure after transplantation. The results of this study suggest that local delivery of DFO using a controlled microsphere release system may reduce resorption and improve revascularization and cellular repopulation to increase new bone ingrowth, potentially expediting OCA osseointegration after transplantation.

Restorative Treatments for Cervical Spinal Cord Injury, a Narrative Review.

A narrative review. To summarize relevant data from representative studies investigating upper limb restorative therapies for cervical spinal cord injury. Cervical spinal cord injury (SCI) is a debilitating condition resulting in tetraplegia, lifelong disability, and reduced quality of life. Given the dependence of all activities on hand function, patients with tetraplegia rank regaining hand function as one of their highest priorities. Recovery from cervical SCI is heterogeneous and often incomplete; currently, various novel therapies are under investigation to improve neurological function and eventually better quality of life in patients with tetraplegia. In this article, a narrative literature review was performed to identify treatment options targeting the restoration of function in patients with cervical SCI. Studies were included from available literature based on the availability of clinical data and whether they are applicable to restoration of arm and hand function in patients with cervical SCI. We describe relevant studies including indications and outcomes with a focus on arm and hand function. Different treatment modalities described include nerve transfers, tendon transfers, spinal cord stimulation, functional electrical stimulation, non-invasive brain stimulation, brain-machine interfaces and neuroprosthetics, stem cell therapy, and immunotherapy. As the authors' institution leads one of the largest clinical trials on nerve transfers for cervical SCI, we also describe how patients undergoing nerve transfers are managed and followed at our center. While complete recovery from cervical spinal cord injury may not be possible, novel therapies aimed at the restoration of upper limb motor function have made significant progress toward the realization of complete recovery.

Human Health Adaptation Strategies to Climate-Induced Extreme Weather Events: A Systematic Review

This systematic review evaluates the health impacts of climate-induced extreme weather events and the effectiveness of various adaptation strategies. Seventeen studies were analyzed, focusing on adaptation measures such as agricultural adjustments, renewable energy, ecosystem restoration, infrastructure redesign, and public health interventions. Significant health impacts were identified, including increased morbidity and mortality due to heatwaves, floods, and vector-borne diseases. The success of adaptation strategies was found to be highly dependent on local context, implementation capacity, and sustainability. This review underscores gaps in data quality, the generalizability of findings, and the integration of adaptation measures into public health policies. An urgent need exists for interdisciplinary approaches and community engagement to ensure sustainable, equitable health outcomes in the face of climate change. Future research should focus on these areas to strengthen public health resilience.

Bibliometric Analysis of Platelet-Rich Plasma Treatment for Hair Restoration, Facial Rejuvenation, Dental Procedures, and Gynecological Rejuvenation

Introduction: Autologous platelet-rich plasma (PRP) technologies offer an attractive treatment option for various medical fields. Owing to its high concentration of growth factors, PRP has been posited to induce proliferation, differentiation, and angiogenesis at the cellular level, as well as wound-healing and remodeling at the tissue level. The goal of the present bibliometric analysis was to characterize the growing body of literature concerning PRP use in various medical applications. Methods: A comprehensive literature search was performed on June 28, 2024, using Web of Science and SCOPUS databases, covering all available publications in selected categories from 2001 to present. Results: PRP use for hair restoration had both the greatest number of total publications among the investigated applications, whereas PRP use in dental procedures had the longest-standing history of publications. PRP use in hair restoration and facial rejuvenation had the greatest number of placebo-controlled and double-blinded randomized controlled trials; however, the impact of results may suffer from a lack of consistency in PRP preparation and outcome measurement between different studies. Conclusion: To effectively validate the utility of PRP across various medical interventions, careful consideration of methodology should be undertaken for future studies to ensure validity of results.

A differentiated approach to the surgical treatment of intraarticular fracture of the proximal tibia

Background. For a long time, the question of optimal ways and methods of surgical treatment of fractures of the proximal part of the tibia (PPT) remains debatable. The purpose was to study the results of surgical treatment of fractures of the PPT using differentiated use of minimally invasive techniques. Materials and methods. The work consisted of a prospective analysis of the treatment outcomes of 87 patients who were treated 2018 to 2023. Fractures were classified according to Schatzker. The tactics of surgical treatment depended on the type of fracture, the age of the patients and the presence of concomitant diseases. A comprehensive assessment of knee function was performed using the Knee Society Score. For X-ray assessment of the degree of progression of post-traumatic arthritis, the Resnik/Niwoyama system was used. ­Results. The results of surgical treatment were studied in terms from 6 to 24 months. 19.8 % of excellent, 57.5 % good, 15.6 % sa­tisfactory and 7.1 % unsatisfactory treatment results were obtained. Progression of post-traumatic arthritis was observed in 36 patients (28 patients at one stage, 4 subjects at 2 stages and 5 patients at 3 stages). Of the complications, 7 (8.0 %) were surgical site infections, which required debridement of the focus and longer antibiotic therapy. Over time, loss of reposition and secondary displacement were identified in 5 (5.7 %) cases. The most common complications were the progression of knee osteoarthritis, the development of contractures in 11 (12.6 %) patients. Conclusions. The use of a differential approach to the surgical treatment of intra-articular fractures of PPT, based on the severity of injuries according to Schatzker, allowed to obtain positive functional results in 77.3 % of the victims. The negative consequences of intra-articular fractures of the tibial plateau that worsen the functional outcomes of treatment include the progression of knee osteoarthritis. The degree of its manifestations is largely determined by the severity of the injury, the quality of reduction, the stability of fragment fixation, and the rationality of restorative treatment and rehabilitation.

Impact of Dental Treatment Simulation App on Anxiety of Pediatric Dental Patients: An Observational Study

ABSTRACT Aim: The study aimed to investigate the effect of a dental treatment simulation app on the anxiety levels of pediatric dental patients. Materials and Methods: Forty children, aged 4–8 years and with no prior dental experience, were randomly assigned to either the control group (group I) or the dental app group (group II). The children’s anxiety levels were measured before and after undergoing restorative dental treatment, using the Chota Bheem Chutki pictorial scale. Results: The initial anxiety levels were similar across both groups. Post treatment, the dental app group exhibited a significant reduction in anxiety compared to the control group. This suggests that the simulation app has a beneficial effect in lowering dental anxiety in children. Conclusion: The dental treatment simulation app can effectively reduce pre and postoperative anxiety in pediatric patients, potentially enhancing their overall dental experience.

High-intensity pulse magnetic therapy and drinking mineral water in rehabilitation treatment of patients with chronic pancreatitis at inpatient stage

BACKGROUND: Sanogenetic effects of physical factors, providing restoration of disturbed functions of the organism, are the basis for their inclusion in the standardised programme of restorative treatment of patients with chronic pancreatitis. AIM: To study the effectiveness of high-intensity pulse magnetic therapy and low-mineralized drinking mineral waters in the restorative treatment of patients with chronic pancreatitis at the inpatient stage. MATERIALS AND METHODS: There has been carried out an open-label, randomized, controlled, prospective study of 125 patients with chronic pancreatitis. The patients were divided into 3 groups using the simple randomization method. In the control group (n=40) the patients underwent restorative treatment in accordance with federal clinical guidelines; in the group of comparison (n=42) he patients were additionally prescribed low-mineralized drinking mineral water; in the main group (n=43) the patients had high-intensity pulse magnetic therapy in addition to the treatment of the group of comparison. The effectiveness of rehabilitation measures was monitored using a visual analogue scale, a carbolene test, a hospital scale of anxiety and depression. RESULTS: The statistical analysis showed that the inclusion of drinking mineral water and high-intensity pulse magnetic therapy contributed to a significant reduction of pain (p 0.01) and dyspeptic syndromes (p 0.01), an improvement in motor evacuation function of intestine (p 0.01), a decrease in enzymatic activity and the severity of anxiety-depressive manifestations (p 0.01). The effectiveness of the developed programmes of restorative treatment of the patients suffering from chronic pancreatitis was 87.8–92.5%, the standardized programme ― 78.5%. CONCLUSION: The inclusion of drinking mineral waters and high-intensity pulse magnetic therapy in the standardized program of restorative treatment of the patients suffering from chronic pancreatitis at the inpatient stage provides a significant restoration of pancreatic external secretory function.

Leveraging extensive soil, vegetation, fire, and land treatment data to inform restoration across the sagebrush biome

ContextWidespread ecological degradation has prompted calls for massive global investments in ecological restoration, yet limited resources necessitate efficient application of restoration efforts. In western North America, altered fire regimes are increasing the scale of restoration needed to preserve the sagebrush (Artemisia species) biome but prioritizing and implementing effective restoration is complicated by the vast and heterogeneous sagebrush landscape, which includes gradients in climate, disturbance, and species composition.ObjectivesTo develop spatially explicit and context-dependent estimates of treatment efficacy and sagebrush recovery rates.MethodsWe leveraged a suite of spatio-temporally extensive datasets to evaluate the influence of restoration treatments and environmental conditions on trends in post-disturbance sagebrush cover, with an emphasis on understanding differences between sites recovering naturally and sites receiving restoration treatments. We used estimates from these models to develop spatially explicit projections for sagebrush recovery, conditional on disturbance, restoration practice, and environmental conditions.ResultsWe found seeding Artemisia spp. increased sagebrush cover over time relative to natural recovery, but this relationship depended on spring soil moisture availability and treatment methods. Natural recovery was positively influenced by soil moisture and sagebrush cover and negatively influenced by cumulative burns and annual herbaceous cover, while the influence of perennial herbaceous cover varied with soil moisture.ConclusionsOur results provide biome-wide insights and spatially explicit tools that can inform economic cost-effectiveness analyses, restoration prioritization tools, and other scientific endeavors to ensure managers have the tools and information needed to effectively steward the sagebrush biome in a rapidly changing world.

Anxiolytic Effect of Jasmine Aromatherapy in Pediatric Dental Procedures: A Single-Blinded Randomized Placebo-Controlled Trial

Objectives: The aim of the present investigation was to evaluate the possible anxiolytic effect of jasmine aromatherapy in pediatric dental procedures. Materials and Methods: A parallel randomized single-blinded placebo-controlled clinical trial was designed and conducted from February 19 until April 19, 2020, on children aged 7 to 12 years-old requiring class 1 restorative treatment of primary or permanent tooth with infiltration anesthesia. Interventions were defined as 15 minutes of aromatherapy using 2mL of jasmine extract for the intervention group, and with water for the control group. Outcomes were defined as child’s anxiety and pain perception, measured by modified child dental anxiety scale (MCDAS), visual analogue scale (VAS) and changes of vital signs. After the patients received interventions based on their groups, their data was collected and analyzed. We used parametric tests and linear regression for outcome comparisons. Results: 56 patients were randomized and allocated in two groups, 28 to each. The groups did not differ significantly regarding age, sex, heart rate and O2 saturation before, during, and after procedures. Based on multivariable regression, the intervention group showed a significantly reduced MCDAS (B (95% CI)=-2.11 (-4.09, -0.13), P=0.04) and VAS (B (95% CI)=-2.30 (-3.50, -1.10), P<0.001) scores. Conclusion: Jasmine aromatherapy showed to be effective in reducing children’s anxiety and pain perception during dental procedures and therefore, can be suggested as a cheap and practical complementary method in dental practice.

МЕЗО-ФОРТЕ ТЕРАПИЯ В НЕЙРОРЕАБИЛИТАЦИИ ДЕТЕЙ С МИОПИЕЙ — ПИЛОТНОЕ ИССЛЕДОВАНИЕ

This article presents the results of a pilot clinical and experimental study of the prospects for neurorehabilitation of children with myopia using Meso-Forte Therapy (MFT), an innovative hardware method of restorative treatment using digital music therapy programs. For the first time, data from complex psycho physiological and ophthalmological studies is published, revealing the mechanisms of corrective regulation of the psycho emotional status, the autonomic nervous system, and the tone of the accommodating muscles of the eye using the main algorithms of musical and acoustic effects.

Projeto de extensão: resgatando sorrisos

The article addresses restorative and aesthetic dentistry, highlighting the importance of adhesion of materials to mineralized dental tissues. The philosophy of minimally invasive restorative treatment is based on principles of prevention and maximum preservation, with minimal intervention in dental structures. Dental aesthetics are subjective, influenced by several factors, and despite advances in aesthetic materials, the need for clinical evaluations on the behavior of composite resin restorations is increasing. In the Brazilian context, where the provision of government dental treatment is limited, perceived need becomes an important predictor of the use of dental services. There is a significant demand for restorative dentistry procedures, often performed by undergraduate and postgraduate students. The article highlights the creation of an Orthodontics Extension Project to deal with repressed demand, although new activities are necessary. It is concluded that initiatives such as extension projects are essential to mitigate the lack of care for the population and prepare academics for clinical practices in restorative dentistry.

Forest restoration benefits common and rare wood-decomposing fungi with a delay

Decline in the amount of dead wood deteriorates habitats for saproxylic organisms globally. This could be compensated by restoration, but it is poorly understood how created dead wood corresponds to the habitat requirements of saproxylic species. Using a large-scale field experiment of 30 restoration sites across Finland, we studied the long-term (5–15 years) effects of dead wood creation on wood-decomposing fungi (polypores) in Norway spruce and Scots pine dominated forests. All studied conservation areas had been used for timber production prior to conservation. The average amount and diversity of woody debris was higher on the restoration treatments than on the non-restored controls. Altogether, 56 polypore species were recorded. Restoration treatments had 1.4 and 8 times more species and observations than controls. Eight red-listed polypore species were observed, six on the restored plots (four only from the created dead wood) and two on the controls. Species composition of polypore assemblages differed between the restoration and control treatments, as well as between the spruce- and pine-dominated forests. Following restoration, temporal changes in the polypore assemblages were clear but only partly related to dead wood creation. Unlike previous short-term studies, our results show that dead wood creation by felling and ring-barking trees benefits not only common but also indicator and red-listed polypore species; indeed, 15 years after restoration all red-listed species occurred on created dead wood. As some red-listed species occurred solely on naturally fallen trees five to ten years after restoration, created dead wood alone cannot substitute for natural dead wood.

Evaluation of caries risk assessment practices among dental practitioners in Guangzhou, China: a cross-sectional study.

This cross-sectional study aimed to investigate dental practitioners' knowledge and practices regarding Caries risk assessment (CRA) in routine clinical practice in Guangzhou, China. An online questionnaire was disseminated to dental practitioners to gather socio-demographic information, factors associated with CRA, the implementation of preventive treatment, and the level of awareness regarding personalized preventive treatment in relation to CRA. Statistical analyses included descriptive statistics, Chi-square tests, ANOVA, MANCOVA, linear regression, and scatter plots. Out of the 695 dental practitioners who were contacted, 206 dentists participated in the online survey. However, out of the total number of dentists, 198 were successfully recruited, while the remaining 8 dentists had incomplete data in their questionnaires. 92.4% of dentists provided in-office fluoride treatments, and 73.2% held a strong belief in the correlation between current oral hygiene and tooth cavities. 23.7% of dentists evaluated caries risk on an individual basis, and a significant 41.9% never utilized a particular type of CRA. 53.5% of dentists recommended non-prescription fluoride rinses, whereas 51% advocated prescription fluoride treatments. Significant statistical relationships were found between the use of in-office fluoride and the effectiveness of restorative treatment (P < 0.05). Additionally, a significant association was discovered between the use of a specific form for CRA and the kind of dental school (P < 0.05). The study suggests that a significant number of dental practitioners in Guangzhou, China, do not utilize dedicated assessment forms for CRA in their routine professional activities. These findings highlight the im-portance of encouraging dentists to utilize CRA systems to effectively identify patients who are at risk of acquiring dental caries.

Impact of restorative dental procedures on periodontal health: A comprehensive review

Restorative dental procedures play a crucial role in restoring function and aesthetics to damaged teeth, yet their impact on the periodontium—comprising the gingiva, periodontal ligament, cementum, and alveolar bone—cannot be overlooked. This review aims to explore the relationship between restorative dental treatments and periodontal health, emphasizing the potential risks and considerations involved. Factors such as improper crown placement, overhanging restorations, subgingival margin placement, and inadequate proximal contact can lead to periodontal inflammation, tissue damage, and bone loss. The integration of restorative and periodontal care is essential to ensure long-term success and to prevent adverse outcomes such as gingival recession, periodontal pocket formation, and compromised periodontal support. This review highlights the importance of precise clinical techniques, appropriate material selection, and careful case planning to minimize detrimental effects on the periodontium. Additionally, the role of regular periodontal maintenance and patient education in preserving periodontal health following restorative procedures is underscored. Understanding the delicate interplay between restorative interventions and periodontal health is vital for clinicians to achieve optimal treatment outcomes and maintain the integrity of both the teeth and supporting structures.

PROBLEMS OF CHOOSING A METHOD OF DENTAL TREATMENT OF TEETH AFTER ENDODONTIC INTERVENTION

The optimal way to restore the anatomical structure of teeth after endodontic intervention is a controversial topic. Teeth after endodontic intervention have different properties compared to intact living teeth. Changes in these properties are associated with volumetric loss of hard tissues, caries, final preparation of the cavity taking into account access to endodontic treatment. Choosing the optimal method of dental treatment of teeth requires compliance with many factors, such as: prevention of infection penetration into root canals, restoration of tooth contacts, restoration of chewing functions, protection against further carious and non-carious destruction, restoration of tooth aesthetics. Dentists are now more than ever aware of the interdependence of the endodontic and restorative aspects of dental treatment and how much this will affect achieving the best long-term outcome. Controversies of the clinical relevance of endodontic and restorative treatment choice issues are mostly unanswered based on clinical data and scientific evidence. The modern approach to tooth restoration after endodontic intervention is an important topic. To improve clinical outcomes, it is important to determine the effectiveness of treatment, the importance of preserving tooth structure, the choice of treatment method with restorative materials, and the integration of digital dentistry to improve diagnosis and treatment principles. Research rationale. The purpose of this study is to find and use literature data on the effectiveness of modern methods of dental treatment after endodontic intervention in Ukraine. Materials and methods. Scientific data from a review and systematic analysis of the literature were used. Materials were searched using the Google Scholar, PubMed, Google Scholar databases and open sources of the World Health Organization, the Ministry of Health of Ukraine and other government web portals of Ukraine. Results, Discussion. After conducting a literature analysis to compare the effectiveness of using cast metal inserts and fiberglass posts, we can come to the conclusions that retrospective studies on the relationship between successful restorations and such factors as the type of tooth, the volume of residual hard tissues, the number of occlusal contacts, the type of the final restoration and the position of the tooth in the dental arch are the main criteria for choosing a treatment method. A controversial choice is that metal abutments are associated with a higher risk of root fracture, their manufacture requires laboratory techniques, while the use of fiberglass posts is associated with a higher risk of decementation, and overloading of fiberglass posts leads to their fractures. Conclusions. Decision-making and the choice of methods of dental treatment after endodontic intervention remain difficult. However, the interdependence of endodontic treatment and restoration of the crown part of the tooth is clearly established. Physicians must consider both aspects of treatment equally to ensure the best possible outcomes for their patients. The use of digital scanning enables an accurate volumetric assessment of the residual hard tissues of the tooth, which can be used to provide tangible qualitative results of the analysis and decision-making with the choice of treatment method. The choice of treatment method is not defined in a single protocol and requires further careful study with new experimental developments, based on the latest technologies of world leaders in dentistry.

Vegetation Succession for 12 Years in a Pond Created Restoratively.

The Najeoer Pond was created in a rice paddy as a part of a plan to build the National Institute of Ecology. To induce the establishment of various plants, the maximum depth of the pond was 2.0 m, and diverse depths were created with a gentle slope on the pond bed. When introducing vegetation, littoral and emergent vegetation were first introduced to stabilize the space secured for the creation of the pond, whereas the introduction of other vegetation was allowed to develop naturally. In this pond, floating, emergent, wetland, and littoral plants have been established to various degrees, reflecting the water depth and water table. As a result of stand ordination, based on vegetation data obtained from the created Najeoer Pond and a natural lagoon selected as the reference site, the species' composition resembled that of the reference site. Diversity, based on vegetation type, community, and species, tended to be higher than that of the reference site. The proportion of exotic species increased due to the disturbance that occurred during the pond creation process but continued to decrease as the vegetation introduced during the creation of the pond became established. Considering these results comprehensively, the restorative treatment served to increase both the biological integrity and ecological stability of the pond and, thus, achieved the creation goal from the viewpoint of the pond structure.

A Review on Ashwagandha and Triphala for Treatment of Cataract

This article's goal is to review the available data about triphala's therapeutic use and efficacy. One of the earliest forms of medicine seen in conventional medical systems like Ayurveda is the use of herbs. A staple of gastrointestinal and restorative treatments is triphala, a popular and highly effective polyherbal herbal drug composed of the fruit of the botanical different species Emblica officinalis (Amalaki), Terminalia bellerica (Bibhitaki), and Terminalia chebula (Haritaki).Emblica officinalis, Terminalia chebula, as well as Terminalia belerica combine to form Triphala (TP). The goal of the current investigation was to evaluate its anti-cataract efficacy using both in vitro and in vivo tests in an experimental model of cataract caused by selenite.

Insight on physical–mechanical properties of one-part alkali-activated materials based on volcanic deposits of Mt. Etna (Italy) and their durability against ageing tests

In recent years, there has been a growing interest in one-part alkali-activated materials, which utilize solid-form alkali activators, within the construction industry. This approach is becoming popular due to its simpler and safer application for cast-in-situ purposes, as compared to the conventional two-part method. At this purpose, we have pioneered the use of volcanic deposits of Mt. Etna volcano (Italy) as precursor for the synthesis of a unique one-part formulation. This was done to assess its performance against both traditional and two-part alkali-activated materials. The study employed a comprehensive range of investigative techniques including X-ray powder diffraction, Fourier transform infrared spectroscopy, hydric tests, mercury intrusion porosimetry, ultrasound, infrared thermography, spectrophotometry, contact angle measurements, uniaxial compressive strength tests, as well as durability tests by salt crystallization and freeze–thaw cycles. The key findings on the studied samples are as follows: i) small size of pores and slow absorption-drying cycles; ii) satisfying compactness and uniaxial compressive strengths for building and restoration interventions; iii) high hydrophily of the surfaces; iv) lower heating dispersion than traditional materials; v) significant damage at the end of the salt crystallization test; vi) excellent resistance to freeze–thaw cycles. These newly developed materials hold promises as environmentally friendly options for construction applications. They offer a simplified mixing process in contrast to the conventional two-part alkali-activated materials, thus providing an added advantage to this class of materials.