This paper provides a comprehensive overview of sustainable supply chain practices, focusing on innovative initiatives in both the United States (USA) and Africa. As the global community grapples with environmental challenges and seeks to create a more sustainable future, the supply chain industry plays a pivotal role in driving positive change. This review explores key sustainable supply chain practices, shedding light on the distinctive approaches taken by businesses in the USA and Africa. In the USA, sustainable supply chain practices are characterized by a growing emphasis on environmental responsibility, ethical sourcing, and corporate social responsibility. Companies are increasingly adopting eco-friendly logistics strategies, such as the use of renewable energy in transportation and distribution networks. The integration of advanced technologies, including Internet of Things (IoT) devices and blockchain, is facilitating transparency and traceability throughout the supply chain, ensuring that sustainable practices are upheld from production to delivery. In contrast, Africa presents a unique landscape where sustainable supply chain practices are often influenced by socio-economic factors, resource constraints, and the need for inclusive development. Initiatives in Africa focus on promoting local sourcing, community engagement, and fair trade practices. Innovative approaches include the use of alternative and locally sourced materials, as well as the development of eco-friendly packaging solutions. Additionally, collaboration between businesses and local communities plays a significant role in fostering sustainable practices and creating a positive impact on the social and environmental aspects of the supply chain. This review also highlights challenges faced by both regions, such as regulatory frameworks, infrastructure limitations, and the need for capacity building. Despite these challenges, the growing recognition of sustainability as a critical business imperative is driving a paradigm shift in supply chain practices. This review contributes to the understanding of sustainable supply chain practices by examining innovations in both the USA and Africa. By identifying commonalities and distinctions, it offers insights that can inform global strategies for building resilient, environmentally conscious, and socially responsible supply chains in the pursuit of a sustainable future.
 Keywords: Supply Chain, Innovation, USA, Africa, Sustainability.