This study combines the Gaussian regression algorithm to propose a nonlinear regression model that can be used to evaluate the seismic vulnerability of regional hospitals and school buildings. The failure features and disaster mechanisms of hospital and school buildings affected by the Jishishan (JSS) earthquake on December 18, 2023, and the Wenchuan (WC) earthquake on May 12, 2008, were reported. The samples of 252 damaged buildings (37 hospitals and 215 schools) in Dujiangyan city affected by the Wenchuan earthquake for which the author participated in the survey were collected and counted. Hospitals and school buildings were classified according to the types of reinforced concrete (RC) and masonry structures, and earthquake vulnerability probability matrices for hospital and school building clusters were established considering the actual failure probabilities. A total of 2103,213 acceleration records (from the Wenchuan earthquake) monitored by 12 real stations were selected. Using dynamic time history and response spectrum analysis methods, time history and spectrum curves were generated, considering the influence of different seismic directions. Using the developed Gaussian regression model, vulnerability comparison curves and parameter matrices considering multiple regression algorithms were generated. This paper considers the effects of the construction year and number of floors on the seismic vulnerability of hospital and school buildings. Seismic vulnerability curves and failure probability matrices were generated and established on the basis of actual structural failure probabilities. According to regression and vulnerability surface analysis, the evaluation results of the proposed model are highly consistent with actual field observations.
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