Resource For Pharmaceutical Industry Research Articles

Phytochemical screening (qualitative) of certain medicinal plants of Saharanpur city

Saharanpur city is situated close to the borders of Haryana and Uttarakhand states, the city is surrounded by a fertile agricultural region. Medicinal plants are the major source of raw materials and good resources for pharmaceutical industry. These are the good source of primary and secondary metabolites. In present study phytochemical screening of three medicinal plants of Saharanpur city i.e. Achyranthus aspera, Euphorbia hirta, Parthenium hysterophorus were carried out by using standard methods for conducting Qualitative phytochemical analysis and studying the presence of active compounds like Alkaloids, Tannins, Saponins, Glycosides, Phenols, Flavonoids, Anthroquinone, Terpenoids and Steroids. Achyranthus aspera showed maximum of these phytocompounds in ethanolic extract. Ethanolic extracts of all plant species revealed the presence of most of the phytochemicals

Finding new sources from “using different plants as the same herb”: A case study of Huang-lian in Northwest Yunnan, China

Ethnopharmacological relevanceTraditional and local medicinal knowledge would be useful for finding pharmaceutical resources. Ethnopharmacological methods, especially quantitative analysis could help us to pre-screen herbs in field studies. “Using different plants as the same herb” is common in both traditional and local medicinal systems in China. In terms of medicine safety, it is not best choice, for it would lead to difficulty in controlling the quality, safety and efficacy of herbs. However, from the perspective of finding new resources for pharmaceutical industry, it would be beneficial. The usage of Huang-lian is one of the typical examples of “using different plants as the same herb”. According to the previous Phytochemical and Pharmacological studies, berberine is the common effective compound of most of the species used as Huang-lian. Recently, berberine and other effective compounds of Huang-lian have gained much more attention and will become more popular in both medicinal researches and pharmaceutical industry. In our preliminary field work, we found that dozens of plant species might be used as Huang-lian by local people in Northwest Yunnan, an area well known by its rich biodiversity and culture diversity. These herbs might have potential value for pharmaceutical industry, for example, it could be used as the new resources to extract berberine and other effective compounds. Due to this, it is very necessary to collect, identify, document, and analyze the herbs used as Huang-lian in NW Yunnan. In the present study, we focused on that how to use traditional and local medicinal knowledge to find resources for pharmaceutical industry. Material and methodsIn the field work, interviews and participative observation were used. In the quantitative analysis of the local knowledge, Informant consensus factor (Fic), Use value (UV) and Relative frequency of citation (RFC) were used. Results and discussionA total of 230 key informants were interviewed and 29 plant species belonging to 8 families and 11 genera used as Huang-lian were collected in the study area. Diarrhoea had the highest value of Fic.xiana had the highest value of UV and RFC. The main effective compounds of most of these species were related to the protoberberine group of isoquinoline alkaloids, e.g. berberine, jatrorrhizin and palmatine, according to the previous phytochemical studies. ConclusionThe range of sources of Huang-lian were very wide in NW Yunnan. Treating diarrhoea was the most common use of these species, most of which contained berberine. Based on the results of quantitative analysis, M. duclouxiana may had the greatest potential to future uses, e.g. as a resource for pharmaceutical industry. In the present study, we did not discuss whether the herbs used as Huang-lian could replace the standard Huang-lian in traditional or local medicine or not, and we just wanted to explore how this phenomenon could be used to find new resources for pharmaceutical industry.

PHYTOCHEMICAL SCREENING OF CERTAIN PLANT SPECIES OF AGRA CITY

Plant kingdom harbours an inexhaustible source of active ingredients invaluable in the management of many intractable diseases. Phytochemical techniques played a significant role in searching raw materials and resources for pharmaceutical industry. Preliminary Phytochemical tests are helpful in finding and locating chemical constituents which are source of pharmacologically active principles. Hence during the present study. Phytochemical screening of six native plants of Agra city i.e. Achyranthus aspera, Acalypha indica, Euphorbia hirta, Lindenbergia indica, Parthenium hysterophorus and Peristrophe bicalyculata were carried out by employing standard methods for conducting Qualitative phytochemical analysis for studying the presence of active compounds like Alkaloids, Tannins, Saponins, Glycosides, Phenols, Flavonoids, Anthroquinone, Terpenoids and Steroids. Ethanolic extract of Achyranthus aspera showed all of these phytocompounds except Tannins in comparison to other extracts. However ethanolic extracts of all plant species revealed the presence of most of the phytocompounds in comparison to other extracts tested. Successive isolation of phytocompounds from plant materials depended on the type of solvent used in extraction procedure. The qualitative changes in the Phytochemical analysis of tested plant species are correlated to methods of preparation. The plants tested are found to be potential due to the presence of various active principles among which Achyranthus aspera is found to be constituted of various primary & secondary metabolites which can be quantified for application in pharmaceutical industry.