Resource-rich Environments Research Articles

Biomass prediction of sea lamprey population based on dynamic feature matrix composite differential equation system

This article presents a mathematical model to predict sea lamprey biomass, addressing the species' impact on the Great Lakes fishery. The model, comprising a Dynamic Age Pyramid and a Multi-species Lotka-Volterra system, captures the complex life stages and behaviors of sea lampreys. It simulates their diet, habits, and growth parameters across different ages, considering their adaptive sex ratio variation. Key findings include the model's ability to dynamically update sea lamprey population characteristics annually in response to environmental changes. Simulations show that populations with dynamic sex ratios reach equilibrium faster, with an increasing female proportion over time in resource-rich environments. However, these populations exhibit less resilience to rapid environmental shifts compared to those with stable sex ratios. The study concludes that the model offers a valuable tool for understanding complex organism-environment interactions and enhances traditional ecological models by providing a dynamic, biologically meaningful population feature matrix. This innovation aids in managing invasive species like sea lampreys without harming native ecosystems.

Why hematopoietic stem cells fail in Fanconi anemia: Mechanisms and models.

Fanconi anemia (FA) is generally classified as a DNA repair disorder, conferring a genetic predisposition to cancer and prominent bone marrow failure (BMF) in early childhood. Corroborative human and murine studies point to a fetal origin of hematopoietic stem cell (HSC) attrition under replicative stress. Along with intriguing recent insights into non-canonical roles and domain-specific functions of FA proteins, these studies have raised the possibility of a DNA repair-independent BMF etiology. However, deeper mechanistic insight is critical as current curative options of allogeneic stem cell transplantation and emerging gene therapyhave limited eligibility, carry significant side effects, and involve complex procedures restricted to resource-rich environments. To develop rational and broadly accessible therapies for FA patients, the field will need more faithful disease models that overcome the scarcity of patient samples, leverage technological advances, and adopt investigational clinical trial designs tailored for rare diseases.

Resource availability enhances positive tree functional diversity effects on carbon and nitrogen accrual in natural forests

Forests harbor extensive biodiversity and act as a strong global carbon and nitrogen sink. Although enhancing tree diversity has been shown to mitigate climate change by sequestering more carbon and nitrogen in biomass and soils in manipulative experiments, it is still unknown how varying environmental gradients, such as gradients in resource availability, mediate the effects of tree diversity on carbon and nitrogen accrual in natural forests. Here, we use Canada’s National Forest Inventory data to explore how the relationships between tree diversity and the accumulation of carbon and nitrogen in tree biomass and soils vary with resource availability and environmental stressors in natural forests. We find that the positive relationship between tree functional diversity (rather than species richness) and the accumulation of carbon in tree biomass strengthens with increasing light and soil nutrient availability. Moreover, the positive relationship between tree functional diversity and the accumulation of carbon and nitrogen in both organic and mineral soil horizons is more pronounced at sites with greater water and nutrient availabilities. Our results highlight that conserving and promoting functionally diverse forests in resource-rich environments could play a greater role than in resource-poor environments in enhancing carbon and nitrogen sequestration in Canada’s forests.

The Association between Frailty, Quality of Life and Resilience in Community-dwelling Retirement Village Residents

ObjectivesHousing quality has significant impact on the wider determinants of health and quality of life (QoL). Retirement villages are considered age-friendly accommodation for community-dwelling older people, offering a variable range of services and supports. We wished to explore the relationship among frailty, QoL, and resilience in older people residing in retirement villages. DesignCross-sectional analysis within a longitudinal study. Setting and participantsResidents from 33 retirement villages in Auckland, Aotearoa, New Zealand. MethodsFrailty [using an interRAI-Community Health Assessment-based frailty index FI)], QoL [World Health Organization Quality of Life–Brief Version (WHOQOL-BREF) and WHOQOL–Older Adults Module (WHOQOL-OLD)], and resilience [Brief Resilience Scale (BRS)]. Associations among frailty, QoL, and resilience were examined using regression analysis adjusting for confounders. ResultsMean (SD): FI 0.2 (0.1) in 479 residents, BRS 3.7 (0.8) in 395 residents, WHOQOL-OLD total score 69.9 (12.2). FI was inversely related to BRS [adjusted mean difference (MD) −0.35; 95% CI −0.43 to −0.26; P < .001] and WHOQOL-OLD (MD, −5.45; 95% CI −6.89 to 4.01; P < .001). FI inverse relationship was seen across all facets of WHOQOL-OLD and all WHOQOL-BREF facets except psychological. Conclusions and ImplicationsFrailty was inversely related to resilience and multiple domains of QoL in those living in presumed age-friendly and relatively resource-rich environments. Studies exploring causal relationships between these facets could inform interventions necessary to improve QoL and resilience in those living with frailty. Specific multidimensional needs, wishes, and concerns of older people living with frailty needs to be explored in order to potentially intervene on frailty, QoL, and resilience.

Feasibility and acceptability of remote administration of the cold pressor test.

Quantitative sensory testing is often used to investigate pain in the context of experimental and clinical research studies. However, many of the devices used for QST protocols are only available in resource rich environments, thereby inadvertently limiting the possible pool of participants. Development of remote protocols for appropriate QST measures has the potential to reduce barriers to participation in research. Participants with insomnia and Crohn's disease were recruited as part of a clinical trial. We adapted a remote version of the cold pressor test for use during telehealth-based study assessments. Herein, we present data from the baseline assessments including an assessment of feasibility and acceptability of the task. 100% of participants (N = 28) were able to complete the remote cold pressor test using a combination of materials from their homes and mailed by the study team. Temperature changes during the test were minimal and fairly evenly balanced between increases and decreases. Correlations between submersion time and both general and disease specific pain trended toward significance. We demonstrated that a remote version of the cold pressor test is feasible and acceptable in a clinical population and provided a step-by-step protocol for administration to facilitate use in other studies.

Resource Aggregates, Acquisition Decisions, and Resource-Rich Environments: An Inductive Study

Resource Aggregates, Acquisition Decisions, and Resource-Rich Environments: An Inductive Study

Water addition but not reduction alters plant biomass-diversity relationship.

The relationship between plant aboveground biomass and diversity typically follows a unimodal pattern, showing a positive correlation in resource-poor habitats and a negative correlation in resource-rich environments. Precipitation is a crucial resource for both plant biomass and diversity in terrestrial ecosystems. However, the impact of precipitation changes on the relationship between plant biomass and diversity remains unclear. We conduct a water addition field experiment in a semiarid grassland and identify a unimodal relationship between plant biomass and species richness under ambient conditions. Water addition delays the declining phase of this unimodal curve and shift it upward compared to ambient conditions. Our meta-analysis of water addition experiments conducted across major biomes worldwide (grassland, shrubland, desert, and forest) supports this finding, while water reduction does not alter the biomass-diversity relationship. Water addition increases biomass in all climate but only increases species richness in arid and semiarid climate. Similarly, water reduction decreases biomass in all climate but only reduces species richness in arid and semiarid climate. Species richness in dry subhumid and humid climate does not change significantly. Furthermore, our field experiment shows that water addition increases plant diversity while decreasing soil inorganic nitrogen levels. The increase in one resource, such as water, leads to the scarcity of another, such as nutrient, thus postponing the declining phase of the plant biomass-diversity relationship typically observed in resource-rich habitats. Our research contributes to predicting the plant biomass-diversity relationship under changing precipitation conditions and highlights the complex interplay between water availability, nutrient level, and plant diversity.

The Relative Age Effect presents an opportunity for Scottish football to be “better than FC Barcelona”

An overrepresentation of athletes born earlier in the year compared with those born later in the year is known as the relative age effect (RAE). A ten year analysis of professional players across ten of the top European leagues showed the existence of an RAE in the ten years from 2000 (29.3 vs 19.8%, p&lt;0.01) to 2010 (31.9 vs 18.4%, p&lt;0.01) with the RAE becoming more pronounced with time. A sample from the FC Barcelona Model (Doncaster et al., 2020. Front Sports Act Liv, 2, 91) showed a strong RAE within their male football academy in all youth groups becoming less prevalent with increasing age (Q1 Jan-Mar = 0.53 Q2 Apr-Jun = 0.27; Q3 Jul-Sep = 0.14; and Q4 Oct – Dec = 0.06 [χ_3^2= 53.6, p&lt;0.001]). Despite solutions being proposed in the literature, this indicates these solutions are not being utilised effectively within Europe’s top clubs such as FC Barcelona. Our previous work (Craig and Swinton, 2020, Eur J Sports Sci, 21, 1101-1110) identified strong relative age bias in players awarded professional contracts between 2006 and 2016 in a Scottish academy (Q1 = 0.50; Q2 = 0.26; Q3 = 0.20; and Q4 = 0.05 [χ_3^2= 40.9, p&lt;0.001]). Scottish clubs have limited resources in comparison with Barcelona meaning academy efficiency is paramount. The main study aim was therefore to assess any changes in the relative age effect over a ten-year period in an elite Scottish football academy within the academy player pool. A secondary aim was to establish if physical differences exist across each quarter to assess the impact of any potential RAE. Following ethical approval, a retrospective analysis of 512 academy players (from 2006 to 2016) from a Scottish Academy was assessed for anthropometric, physical performance and RAE impact. The range of players in each quarter was Q1 37.0-42.9% versus Q2 22.8-32.4%, Q3 11.9-26.0% and Q4 7.1-14.3%. Odds Ratio analysis indicate a greater chance of selection within the academy when assessing Q1 vs Q4 players quarter comparisons (ranging 3.2-5.2 time more likely to be part of the academy). There was no impact of time on the RAE over the ten years (p=0.3127). When controlling for age group multilevel modelling showed there were no significant differences across quarters in physical measures. Underrepresented Q4 players who transition through academy soccer can match physically their older peers. The finding that there is no improvement in the RAE with time underpins an efficiency that can be integrated. Using established interventions and corrective procedures can ensure no potential is being removed unnecessarily from the development pathway on the basis of RAE, addressing challenges in financially restricted environments such as Scottish football that resource rich environments such as FC Barcelona have not yet overcome.

Exploration of the Blended Learning Model in English Major Education at Private Applied Universities

The integration of the blended learning model in the curriculum of English majors at private applied universities is a strategic response to the evolving demands of higher education. This study explores the potential of blended learning to augment learning outcomes and the overall educational experience. By combining traditional classroom instruction with online learning tools, the model seeks to offer a more flexible and resource-rich environment that can foster student engagement and initiative, thereby promoting a well-rounded development of English language skills and cultural competencies. The research delves into the practical implementation of the blended learning model, examining how it can be tailored to meet the specific needs of English majors. It discusses the integration of technology into the curriculum, the importance of faculty training, and the creation of an interactive and personalized learning experience. The study also emphasizes the need for continuous assessment and feedback mechanisms to ensure the model’s effectiveness. Furthermore, the research highlights the importance of cultivating English talents with practical capabilities, innovative abilities, and an international perspective. It underscores the role of blended learning in preparing students for the global job market by providing them with the necessary language proficiency and cultural understanding.

Marine predators segregate interspecifically by space and time in a sheltered coastal bay.

Marine predators are vital to the healthy functioning of coastal ecosystems, but to understand their roles, it is necessary to elucidate their movement ecology, particularly in relation to one another. A decade's worth of acoustic telemetry data (2011-2020) from Algoa Bay, South Africa, was investigated to determine how two mesopredatory species (teleosts: dusky kob Argyrosomus japonicus, n = 11, and leervis Lichia amia, n = 16) and two top predatory species (sharks: ragged-tooth sharks Carcharias taurus, n = 45, and white sharks Carcharodon carcharias, n = 31) used and shared this bay ecosystem. Multi-annual seasonal fidelity to the bay was exhibited by all species, but differences in residency were observed among species. Similarly, species used space in the bay differently-the teleosts moved less and had movements restricted to the central and western inshore regions of the bay. Conversely, the sharks roamed more, but detections were concentrated in the western part of the bay for C. taurus and in the eastern part of the bay for C. carcharias. Social network analysis showed that species segregated in space and time on a fine scale. However, there was some interaction observed between C. taurus, L. amia, and A. japonicus, but to varying degrees. This is likely because of strong habitat preferences exhibited by each species and predator-prey relationships between these predatory guilds. Results highlight that the sheltered marine Algoa Bay is a resource-rich environment, supporting multiple predators with different hunting strategies albeit similar prey preferences. Finally, these species are likely afforded some protection by the current Greater Addo Elephant National Park Marine Protected Area in the bay but are vulnerable to fishing pressure when they leave this ecosystem.

Small-scale land-use change effects on breeding success in a desert-living social bird

Abstract Human villages in deserts can provide resources in an otherwise stark environment, potentially buffering against extreme environmental conditions. It is thus expected that breeding within these villages would result in higher fitness. However, choosing to raise offspring in these resource-rich environments may have unintended negative consequences. Here, we studied the breeding success of a cooperative breeding bird nesting in habitats with different levels of human disturbance—the Arabian babbler (Argya squamiceps), in the Negev desert of Israel. We recorded 42 breeding attempts from 15 groups between March and July 2022. We examined overall breeding success, brood size, and causes of nest failure. When nestlings were 6 days old, we also calculated daily change in body mass and adult provisioning rate. We found that despite higher resource abundance in villages, proximity to villages did not affect provisioning rate, and nestlings gained less mass at higher temperatures for all nests. Currently, there is no evidence that human villages are providing oases of resources for nesting babblers. Further, various conservation interventions (e.g., encouraging residents to keep cats indoors) could improve babblers’ overall fitness. Ultimately, we highlight how, for some desert specialists, additional resources provided by humans may not do enough to counter potential negative effects.

Safety and efficacy of pelvic arterial embolization for primary postpartum hemorrhage in hemodynamically stable and hemodynamically unstable patients: Is it “time” for a paradigm change?

BackgroundPelvic artery embolization (PAE) is an effective and safe technique for treating postpartum hemorrhage (PPH) with hemodynamic stability. However, its use in hemodynamically unstable patients remains controversial. PurposeTo determine the safety and efficacy of pelvic arterial embolization (PAE) according to the hemodynamic state of primary postpartum hemorrhage (PPH) patients. MethodsThis cohort study was conducted retrospectively, using data from January 2004 to December 2021, in a resource-rich setting at a tertiary Level 1 trauma academic center. A total of 437 patients were diagnosed with PPH during the study period. Of these 437 patients, 161 with primary PPH who underwent PAE were enrolled in the study. The outcomes assessed included the clinical success rate, mortality, the overall success rate, predictive factors for failed PAE, and time-dependent changes in hemodynamic parameters, such as systolic blood pressure (SBP), heart rate (HR), and shock index (SI). Propensity score (PS) matching analysis was performed to assess the influence of specific variables or conditions on the outcomes. ResultsOf the 161 patients who underwent PAE for primary PPH (mean age, 32.9 ± 4.3 [SD]), 85 were retrospectively categorized as having hemodynamic stability (mean age, 32.6 ± 4.1 [SD]), while 76 were categorized as having hemodynamic instability (mean age, 33.3 ± 4.4 [SD]). This study showed PAE for primary PPH had a success rate of 91.9 %, with no significant difference in mortality rates between the groups. The clinical success rate was 98.8 % for patients with hemodynamic stability and 84.2 % for those with hemodynamic instability (p < .001). The overall success rate was 98.8 % for hemodynamic stability and 89.5 % for hemodynamic instability (p = .014). After propensity score matching, the clinical success rate was higher in hemodynamically stable patients than in unstable ones (100 % vs. 86.3 %, p = .013). However, there was no significant difference in the overall success rate (100 % vs. 90.2 %, p = .056). Among the PS-matched population, predictive factors for the failed PAE in primary PPH were hemodynamic instability (adjusted odds ratio [aOR] 21.22, 95 % CI 1.27-355.76; p = .034) and emergency Cesarean delivery with accompanying hemorrhag (aOR 54.00, 95 % CI 11.93-244.56; p = .008). In three groups within a PS-matched population — hemodynamically stable, unstable with successful outcomes, and unstable with unsuccessful outcomes, a generalized linear mixed model (GLMM) analysis for time-dependent changes in hemodynamic parameters revealed a statistically significant difference in SBP, HR, and SI at various time points. ConclusionPelvic arterial embolization of primary postpartum bleeding in hemodynamic instability has been identified as an alternative, safe, and effective life-saving procedure for multidisciplinary treatment in resource-rich environments even after the baseline characteristics are balanced by the PS matching, suggesting it is a primary care option.

Resource availability and disturbance frequency shape evolution of plant life formsin Neotropical habitats.

Organisms use diverse strategies to thrive in varying habitats. While life history theory partly explains these relationships, the combined impact of resource availability and disturbance frequency on life form strategy evolution has received limited attention. We use Chamaecrista species, a legume plant lineage with a high diversity of plant life forms in the Neotropics, and employ ecological niche modeling and comparative phylogenetic methods to examine the correlated evolution of plant life forms and environmental niches. Chamaephytes and phanerophytes have optima in environments characterized by moderate water and nutrient availability coupled with infrequent fire disturbances. By contrast, annual plants thrive in environments with scarce water and nutrients, alongside frequent fire disturbances. Similarly, geophyte species also show increased resistance to frequent fire disturbances, although they thrive in resource-rich environments. Our findings shed light on the evolution of plant strategies along environmental gradients, highlighting that annuals and geophytes respond differently to high incidences of fire disturbances, with one enduring it as seeds in a resource-limited habitat and the other relying on reserves and root resprouting systems in resource-abundant habitats. Furthermore, it deepens our understanding of how organisms evolve associated with their habitats, emphasizing a constraint posed by low-resource and high-disturbance environments.

A modified Michaelis-Menten equation estimates growth from birth to 3 years in healthy babies in the USA

BackgroundStandard pediatric growth curves cannot be used to impute missing height or weight measurements in individual children. The Michaelis–Menten equation, used for characterizing substrate-enzyme saturation curves, has been shown to model growth in many organisms including nonhuman vertebrates. We investigated whether this equation could be used to interpolate missing growth data in children in the first three years of life and compared this interpolation to several common interpolation methods and pediatric growth models.MethodsWe developed a modified Michaelis–Menten equation and compared expected to actual growth, first in a local birth cohort (N = 97) then in a large, outpatient, pediatric sample (N = 14,695).ResultsThe modified Michaelis–Menten equation showed excellent fit for both infant weight (median RMSE: boys: 0.22 kg [IQR:0.19; 90% < 0.43]; girls: 0.20 kg [IQR:0.17; 90% < 0.39]) and height (median RMSE: boys: 0.93 cm [IQR:0.53; 90% < 1.0]; girls: 0.91 cm [IQR:0.50;90% < 1.0]). Growth data were modeled accurately with as few as four values from routine well-baby visits in year 1 and seven values in years 1–3; birth weight or length was essential for best fit. Interpolation with this equation had comparable (for weight) or lower (for height) mean RMSE compared to the best performing alternative models.ConclusionsA modified Michaelis–Menten equation accurately describes growth in healthy babies aged 0–36 months, allowing interpolation of missing weight and height values in individual longitudinal measurement series. The growth pattern in healthy babies in resource-rich environments mirrors an enzymatic saturation curve.

The dik-diks of Guli Waabayo: Late Pleistocene net-hunting and forager sociality in eastern Africa

Net-hunting is closely linked to organized labor and hunter-gatherer cooperation in many world regions. At the Rifle Range Site (RRS) in southern Somalia, scholars have argued that Later Stone Age (LSA) foragers developed specialized dwarf antelope hunting strategies—possibly using communal net-drives—to facilitate developing concepts of territoriality around resource-rich inselberg environments during a wet period in the early and middle Holocene. Unfortunately, a lack of radiocarbon dates and faunal data limited detailed zooarchaeological perspectives on changing hunting patterns at the site. The large and well-dated dwarf antelope bone assemblage (1263 specimens) from nearby Guli Waabayo (GW) rock shelter, on the other hand, provides an opportunity to explore proposed relationships between net-hunting and LSA social and economic reorganization in southern Somalia ~ 26–6 thousand years ago (ka). Consistently high dik-dik frequencies (55.2–71.9%) and mortality profiles comprised of individuals from all age groups throughout the sequence do not support previous arguments associating specialized dwarf antelope hunting with territoriality and Holocene climatic amelioration at RRS. Instead, they suggest that LSA foraging groups regularly hunted dik-dik (genus Madoqua) using nets over a ~ 20,000-year period beginning as far back as the arid Marine Isotope Stage 2, 29–14.5 ka. Findings from this study complement recent arguments for greater economic variability in Late Pleistocene eastern Africa and push discussions of forager social change further back in time than previously considered.

Evolution as a result of resource flow in ecosystems: Ecological dynamics can drive evolution.

To see how the flow of energy across ecosystems can derive evolution, I introduce a framework in which individuals interact with their peers and environment to accumulate resources, and use the resources to pay for their metabolic costs, grow and reproduce. I show that two conservation principles determine the system's equilibrium state: conservation of resources- a physical principle stating that in the equilibrium, resource production and consumption should balance, and payoff equality- an economic principle, stating that the payoffs of different types in equilibrium should equal. Besides the equilibrium state, the system shows non-equilibrium fluctuations derived by the exponential growth of the individuals in which the payoff equality principle does not hold. A simple gradient-ascend dynamical mean-field equation predicts the onset of non-equilibrium fluctuations. As an example, I study the evolution of cooperation in public goods games. In both mixed and structured populations, cooperation evolves naturally in resource-poor environments but not in resource-rich environments. Population viscosity facilitates cooperation in poor environments but can be detrimental to cooperation in rich environments. In addition, cooperators and defectors show different life-history strategies: Cooperators live shorter lives and reproduce more than defectors. Both population structure and, more significantly, population viscosity reduce lifespan and life history differences between cooperators and defectors.

Digital entrepreneurship from cellular data: How omics afford the emergence of a new wave of digital ventures in health

Data has become an indispensable input, throughput, and output for the healthcare industry. In recent years, omics technologies such as genomics and proteomics have generated vast amounts of new data at the cellular level including molecular, structural, and functional levels. Cellular data holds the potential to innovate therapeutics, vaccines, diagnostics, consumer products, or even ancestry services. However, data at the cellular level is generated with rapidly evolving omics technologies. These technologies use scientific knowledge from resource-rich environments. This raises the question of how new ventures can use cellular-level data from omics technologies to create new products and scale their business. We report on a series of interviews and a focus group discussion with entrepreneurs, investors, and data providers. By conceptualizing omics technologies as external enablers, we show how characteristics of cellular-level data negatively affect the combination mechanisms that drive venture creation and growth. We illustrate how data characteristics set boundary conditions for innovation and entrepreneurship and highlight how ventures seek to mitigate their impact.

Implications of the Theory of Basic Human Values for the Second Demographic Transition: Interdependence and Individualism in the Era of Self-Fulfillment

I examine the implications of a modern psychological theory of values for the Second Demographic Transition (SDT). The SDT derives its values theory and measurement from Maslow, who noted that resource-rich environments cause value shifts towards personal-focused growth values. However, Maslow has been replaced by the theory of basic human values (TBHV) which distinguishes person and social-focused growth values. This distinction has two important implications for the SDT. First, some individualistic and self-expressive values identified by the SDT are not growth but basic need motivated and therefore functions of resource-poor environments. Second, the TBHV values on interdependence and independence are strongly influenced by gender and reflect preferences for family and care or career. Therefore, these values can be used to address critiques of the SDT based on the stalled gender revolution. I show that distinguishing values as described in the TBHV can be useful for the SDT. I find that benevolence (interdependence) is positively and openness to change (autonomy/stimulation) is negatively related to marriage in the Netherlands using longitudinal panel data and discrete event history models.

A Critical Reassessment of the Kidney Risk Caused by Tetrastarch Products in the Perioperative and Intensive Care Environments.

Purpose: To reassess the results of former meta-analyses focusing on the relationship between novel HES preparations (130/0.4 and 130/0.42) and acute kidney injury. Previous meta-analyses are based on studies referring to partially or fully unpublished data or data from abstracts only. Methods: The studies included in the former meta-analyses were scrutinized by the authors independently. We completed a critical analysis of the literature, including the strengths, weaknesses and modifiers of the studies when assessing products, formulations and outcomes. Results: Both the published large studies and meta-analyses show significant bias in the context of the deleterious effect of 6% 130/0.4-0.42 HES. Without (1) detailed hemodynamic data, (2) the exclusion of other nephrotoxic events and (3) a properly performed evaluation of the dose-effect relationship, the AKI-inducing property of 6% HES 130/0.4 or 0.42 should not be considered as evidence. The administration of HES is safe and effective if the recommended dose is respected. Conclusions: Our review suggests that there is questionable evidence for the deteriorating renal effect of these products. Further well-designed, randomized and controlled trials are needed. Additionally, conclusions formulated for resource-rich environments should not be extended to more resource-scarce environments without proper qualifiers provided.

Health research mentorship in low- and middle-income countries: a scoping review.

The objective of this scoping review was to explore and synthesize the available literature on health research mentorship in low- and middle-income countries (LMICs). Research mentorship is broadly considered a useful strategy to improve research capacities and research outputs. Existing literature and guidance on research mentorship have focused on high-income countries and assumed resource-rich environments. Despite the successful endeavors to improve health research capacity in LMICs, the strategies that work best under different circumstances are poorly understood. There is a need to map and understand the evidence on health research mentorship in the context of LMICs. Sources that reported existing practices, barriers, and mitigation strategies related to health research mentorship in LMICs were included. We searched for published and unpublished studies and reports written in English, Spanish, or Portuguese. The search strategy was not limited by search dates and the last search was conducted on January 28, 2022. The databases searched included MEDLINE (PubMed), Embase, Web of Science Core Collection, CINAHL (EBSCOhost), Cochrane Database of Systematic Reviews, and JBI Evidence Synthesis. We also searched for gray literature in a selection of websites and digital repositories. The JBI scoping review methodology was used. A total of 77 studies and reports were included in the review. The majority of the papers were from Africa (n=28). Others were from Americas (n=7), South East Asia (n=4), East Mediterranean (n=2), and Western Pacific (n=2). The remaining studies were from LMICs that included at least two regional offices. Most of the mentorship projects (n=55) were initiated and funded by institutions from high-income countries. The first authors of 41 papers were primarily affiliated from LMICs. The findings were categorized under a description of research mentorship practices, barriers related to research mentorship, and suggested mitigation strategies. Deliverable-driven training using intensive hands-on mentorship and ongoing peer mentorship programs were some of the non-regular, non-institutionalized approaches used to improve research capacity for junior researchers in LMICs. None of the included papers focused on institutional components of research mentorship in LMICs. The barriers to research mentorship activities in LMICs included lack of clarity on mentorship, cultural variations, unbalanced power dynamics, socio-political influences, language barriers, lack of experienced mentors, and limited local funding. Institutionalizing research mentorship, adapting mentoring methodologies relying on local resources, and addressing and respecting diversity in mentorship programs were among the main strategies identified to effectively implement research mentorship in LMICs. Research mentorship initiatives and practices are limited in LMICs. Few available practices are introduced by researchers and research institutions from high-income countries and yet not institutionalized. The identified existing practices, barriers, and facilitators on health research mentorship could help the design, implementation, and evaluation of programs to institutionalize health research mentorship in LMICs. Open Science Framework: https://osf.io/jqa9z/.