Resonance Sensor Research Articles

Design and Analysis of Multi-Analyte Detection Based Biosensor in the Visible to Near-Infrared (VNIR) Region.

This manuscript introduces a highly sensitive dual-core photonic crystal fiber (PCF) based multi-analyte surface plasmon resonance (SPR) sensor, possessing the ability to detect multiple analytes at once. A chemically stable thin plasmonic substance of gold (Au) layer, holding a thickness of 30 nm, is employed to the outer portion of the stated design that manifests a negative real permittivity. Moreover, an ultra-thin film of aluminum oxide (Al2O3) , having a thickness of 10 nm, is inserted into the exterior of the gold film to calibrate the resonance wavelength as well as magnify the coupling strength. The performance of the sensor is rigorously explored employing the finite element method (FEM), where numerical investigation confirms that the intended sensor model exhibits a peak amplitude sensitivity (AS) of 2606 RIU-1 , as well as a highest wavelength sensitivity (WS) of 20,000 nm/RIU. The achieved outcomes affirm that the sensor design can be conceivably applied in numerous biological; as well as biochemical analyte refractive index (RI) detection to realize the relevant significant applications in the visible to near-infrared (VNIR) region of 0.5 to [Formula: see text].

Measurement of Solid Concentration in Gas–Solid Flows Using a Microwave Resonant Cavity Sensor

Measurement of Solid Concentration in Gas–Solid Flows Using a Microwave Resonant Cavity Sensor

A micro resonant pressure sensor with adjustable quality factor

A micro resonant pressure sensor with adjustable quality factor

Titanium‐Coated Extremely Sensitive SPR Biosensor for Cancer Cell Detection

In this study, a D‐shaped, extremely sensitive surface plasmon resonance (SPR) sensor with a blue shift characteristic is proposed that can be used to identify various malignant cancer cells. A sensing layer made of titanium is inserted to produce intense sensitivity. For the simulation and numerical evaluation of the proposed biosensor, we used the finite element method (FEM) and the COMSOL Multiphysics 5.6 software. To regulate how much light passes through the sensor, which incites the released electrons at the surface of the plasmonic material, air holes in different radii are used. The characteristics that make our proposed sensor superior to other D‐shaped SPR sensors are—it gives an excellent amplitude sensitivity (AS) of 200 RIU−1 also ensures extremely high wavelength sensitivity (WS) spanning from 34,350 to 42,145 nm/RIU with an outstanding spectral resolution of 2.37 × 10−6 RIU. Furthermore, the R2 (0.9966) value is also extremely close to 1 which ensures the quality of our sensor regarding its performance. The given sensor is tailored for four vital human cancers, which are blood cancer, skin cancer, cervical cancer, and adrenal gland cancer. Here, optimization of the structural geometric parameters, plasmonic materials, and material thickness are also conducted in search of the best functionality of the sensor. The offered structure, nonetheless, can be an obvious prologue in the case of the crucial human cancer detection platform due to its mild sensing performances.

High-resolution Resonant Optical Fiber Sensor Interrogation Technique using A Square-wave Modulated DFB Laser Diode

High-resolution Resonant Optical Fiber Sensor Interrogation Technique using A Square-wave Modulated DFB Laser Diode

Piezoelectric PZT film-driven resonant torsional MEMS electric field sensor

Piezoelectric PZT film-driven resonant torsional MEMS electric field sensor

Silver-coated hollow fiber surface plasmon resonance sensor for glucose detection with enhanced limit of detection.

A fiber-optic surface plasmon resonance (SPR) biosensor based on a silver-coated hollow fiber (HF) structure for glucose detection is presented. The sensor surface was immobilized with 4-mercaptophenylboronic acid (PMBA) acting as a glucose recognition monolayer. Then, gold nanoparticles (AuNPs) modified with 2-aminoethanethiol (2-AET) and PMBA were introduced onto the sensor surface after glucose was captured to enhance the wavelength shift of the SPR phenomenon excited by the light transmitted in the wall of the HF sensor. Instead of the conventional one-step sensitization pretreatment commonly used in the deposition process of silver films for fiber-optic SPR sensors, a sensitization-activation two-step activation method was adopted in the fabrication of the proposed sensor. Experiments for glucose detection were performed on the fabricated sensors in the concentration range of 1 nM-1 mM. Results showed that the sensor fabricated by the two-step activation method has a much larger shift of resonance wavelength than the sensor fabricated using the one-step sensitization method. The resonance wavelength shift was found to be linear to the logarithm of the concentration in the range of 1 nM-1 mM. The sensor achieved a limit of detection (LOD) of as low as 1 nM, which is at least an order of magnitude lower than that of other fiber-optic sensors for glucose detection reported previously. The presented HF glucose sensor has the potential for biosensing applications and provides a large reference value in the study of optical fiber SPR sensors for biosensing.

Multi-Disease Detection Using a Prism-Based Surface Plasmon Resonance Sensor: A TMM and FEM Approach.

This research introduces a surface plasmon resonance (SPR)-based biosensor with multilayered structures for telecommunication wavelength in order to detect multiple diseases. The malaria and the chikungunya viruses are taken into account and the presence of these viruses are determined by examining several blood components in healthy and affected phases. Here, two distinct configurations (Al-BTO-Al-MoS2 and Cu-BTO-Cu-MoS2) are proposed and contrasted for the detection of numerous viruses. The performance characteristics of this work have been analyzed using Transfer Matrix Method (TMM) method and Finite Element Method (FEM) method under angle interrogation technique. From the TMM and FEM solutions, it is evident that the Al-BTO-Al-MoS2 structure provides the highest sensitivities of ~270 deg./RIU for malaria and ~262 deg./RIU for chikungunya viruses, with satisfactory detection accuracy of ~1.10 for malaria, ~1.64 for chikungunya, and quality factor of ~204.40 for malaria, ~208.20 for chikungunya. In addition, the Cu-BTO-Cu MoS2 structure offers the highest sensitivities of ~310 deg./RIU for malaria and ~298 deg./RIU for chikungunya, with satisfactory detection accuracy of ~0.40 for malaria, ~0.58 for chikungunya, and quality factor of ~89.85 for malaria, ~86.38 for chikungunya viruses. Therefore, the performance of the proposed sensors is analyzed using two distinct methods and gives around similar results. In a sum, this research could be utilized as a theoretical foundation and first step in the development of a real sensor.

A Novel Design of a Unilateral Nuclear Magnetic Resonance Sensor for Soil Moisture Detection Based on a Simplified Analytical Model

A Novel Design of a Unilateral Nuclear Magnetic Resonance Sensor for Soil Moisture Detection Based on a Simplified Analytical Model

Design and Probing of Prism-Based SPR Nano-Biosensor for Human Sperm Detection.

Human sperm functioning is crucial for maintaining natural reproduction, but its sterility is enhanced by variations in environmental conditions. Because of these agitating properties, powerful computer-aided devices are required, but their precision is inadequate, particularly when it comes to samples with low sperm concentrations. Therefore, for the first time, this article introduces the sulfide material-based structure for the detection of human sperm samples using the prism-based surface plasmon resonance sensor (SPR) Nano-biosensor. The proposed structure is designed on the basis of a prism-based Kretschmann configuration and includes silver, silicon, a sulfide layer, black phosphorus, and a sensing medium. This work takes advantage of the excitement of surface plasmons and evanescent waves in the metal dielectric region. For the detection process, seven sperm samples are taken, with their concentration, mobility, and refractive index measured by the refractometer. The proposed structure provides a maximum sensitivity of 409.17°/RIU, QF of 97.45RIU-1 and a DA of 1.37. The results provide a substantial improvement in comparison to the reported work in the literature.

Surface plasmon resonance sensor based on gold-graphene quantum dots thin film as a sensing nanomatrix for phenol detection

Surface plasmon resonance sensor based on gold-graphene quantum dots thin film as a sensing nanomatrix for phenol detection

Thermal Stabilization of Quality Factor for Dual-Axis MEMS Gyroscope Based on Joule Effect In Situ Dynamic Tuning

Quality factor has played a crucial role in determining the temperature and anti-shock performance of a microelectromechanical system (MEMS) gyroscope. This paper presents an innovative approach to enhance the thermal stability of quality factor for a micro resonant sensors based on Joule effect in-situ dynamic tuning for the first time. By unitizing an active control loop that adjusts the dissipation energy of a resistive element connected to the mechanical structure via monitoring the driving voltage, the device damping can be effectively tuned in real-time, thus stabilizing the quality factor. The proposed method is demonstrated on a vacuumed sealed monolithic dual-axis gyroscope. The results show that the relative variation of the Q-factor significantly reduced by more than 3000× down to ∼150ppm from -40℃ to +60℃, which achieves only ∼30ppm of driving voltage stability with ∼3500× reduction. Benefiting from the quality factor precise control capability, the electrical coupling from the drive mode to the sense mode is therefore suppressed, exhibiting more than three-fold times improvement of the zero bias thermal drift over 100℃ range. This technique is also promising for enhancing the anti-shock performance.

Solid-state electrochemical oxidation with polyelectrolyte membrane stamps for micro-/nanoscale pattern formation on Au surfaces.

Nanoscale-patterned Au surfaces are promising for a wide range of applications from bio/chemical sensors to high-performance electrodes. However, pattern formation using conventional resist-based methods is complex, expensive, and environmentally unfriendly. Herein, we report a novel approach for pattern formation on Au surfaces using solid-state electrochemical treatment with polymer electrolyte membrane (PEM) stamps. During electrolysis, the patterned structure of the PEM stamp was transferred onto the Au surface to form micro- and nanoscale oxide patterns. X-ray analysis of the treated surface confirmed the formation of an oxide film on the Au surface, which was subsequently reduced to metallic Au after air exposure for several weeks. Although the pattern height decreased with air exposure, a patterned structure with a height of several hundred nanometers was maintained following oxide reduction. Reflectance spectroscopy revealed that the patterned Au surface exhibited sharp reflectance peaks, the intensities and positions of which strongly depended on the measurement angle, which are key characteristics of diffraction gratings. This fast and facile electrochemical treatment process is promising for the preparation of patterned Au surfaces that can be applied in optical gratings and localized surface plasmon resonance sensors.

Visual detection of arbitrary mode shape of optomechanical resonant sensor based on silicon nitride membrane

Visual detection of arbitrary mode shape of optomechanical resonant sensor based on silicon nitride membrane

Temperature Detection Based on Surface Plasmon Resonance Sensor for Microwave Ablation

Temperature Detection Based on Surface Plasmon Resonance Sensor for Microwave Ablation

A microwave resonance thin-film sensor for real-time wireless temperature monitoring in composites manufacturing

Composites are of growing importance to today's industries. Curing or consolidation under certain temperatures is a vital process to manufacture composite parts. Great attention has been paid to monitoring the temperature of composite parts being processed. Wireless monitoring methods are extensively explored for their unique advantages in realizing real-time monitoring of specific temperature distribution of the part. Here, a flexible microwave resonance sensor is first introduced to achieve real-time wireless temperature monitoring of composites. When applied to curing processes with different heating rates, it was found that the sensing relationship of the sensor was varied. Through in-depth analysis, the relationship between peak frequencies and temperature was established with consideration of different heating rates. In several curing processes with different heating rates, the mean error of the thin film sensor using a heating rate-related relationship was about 4.23 °C. which can be reduced by more than 43 % compared with the method using a static relationship.

A sensing method based on InSb grating coupled terahertz surface plasmon polariton resonance

A grating-coupled terahertz (THz) surface plasmon polariton (SPP) resonant biochemical sensing structure is designed with simulation, which can be easily prepared by etching a submillimeter grating on the surface of indium antimonide (InSb) substrate. The simulation results based on the phase matching equation show that when the TM-polarized broadband terahertz collimated beam is incident on the InSb grating at a 30° angle, the low-frequency SPP and high-frequency SPP with opposite propagation directions can be simultaneously excited by the –1st and +1st order diffraction beams of the grating, respectively. Since the low-frequency SPP is easy to accurately measure with a commercial THz time-domain spectroscopy devices, the dependence of the resonance characteristics and sensing characteristics of low-frequency SPP on the grating structure parameters is systematically simulated in this paper. The simulation results show that the refractive-index sensitivity of the InSb grating-coupled THz-SPP resonant sensor chip decreases with the increase of the grating period, and is 1.05 THz/RIU at a grating period of 120 μm and an incident angle of 30°. Under these conditions, the sensor chip cannot make a detectable response to the monolayer adsorption of biomolecules, because the evanescent field penetration depth of the low-frequency SPP is much greater than the biomolecular size, resulting in insufficient field-biomolecular interaction at the surface. In order to detect biomolecules, a sensitivity enhancement method based on porous thin films is proposed and analyzed with simulation. The porous films enable not only to enrich biomolecules, but also to extend the interaction between THz-SPP and biomolecules from the molecular size to the entire film thickness, thereby improving the sensitivity of the sensor to biomolecular adsorption. Taking tyrosine adsorption as an example, the simulation results show that when the InSb grating is covered with a porous polymethyl methacrylate (PMMA) film with a thickness of 120 μm and a porosity of 0.4, the sensor sensitivity to tyrosine adsorption is 0.39 THz/unit volume fraction.

Decomposition Mueller matrix polarimetry for enhanced miRNA detection with antimonene-based surface plasmon resonance sensor and DNA-linked gold nanoparticle signal amplification

A decomposition Mueller matrix method is proposed for detection of miRNA and enhanced by using a surface plasmon resonance (SPR). In the proposed approach, a Mueller matrix decomposition method is employed to extract the linear birefringence (LB) and circular dichroism (CD) properties of the miRNA sample. The accuracy of the LB and CD measurements is enhanced through the use of a high-resolution antimonene-based SPR prism coupler with DNA-linked gold nanoparticles (AuNPs). The feasibility of the proposed method is demonstrated by measuring the LB orientation angle (α) and CD property (R) of two miRNA aqueous solutions (hsa-miR-125-5p and hsa-miR-21-5p) over the concentration range of 0∼1000 fM in both cases. The results show that, for both samples, α and R vary linearly with the change in the miRNA concentration. Furthermore, the values of α and R obtained for the two samples are quantifiably different, and hence the selectivity of the proposed SPR sensor is confirmed. Overall, the results highlight the potential of the proposed sensor as a valuable tool for miRNA detection with prospective applications in cancer diagnosis.

Design and Analysis of High-Performance Optical Fiber-Based Surface Plasmon Resonance Sensor for Early Detection of Colorectal Cancer

Design and Analysis of High-Performance Optical Fiber-Based Surface Plasmon Resonance Sensor for Early Detection of Colorectal Cancer

Advancing Sensitivity in Guided-Wave Surface Plasmon Resonance Sensor through Integration of 2D BlueP/MoS2 Hybrid Layers.

The surface plasmon resonance (SPR) signal, generated from the Kretschmann configuration, has been developed as an effective detection technology in chemical and biological sensors. The sensitivity of SPR signals to changes in the surrounding media makes it a valuable tool, as even a slight variation in refractive index can cause a significant change in SPR signals, such as phase, intensity, and resonance angle. However, the detection of ultralow changes in refractive index, which occur in chemical reactions or biological actions, remains a challenge for conventional SPR sensors due to their limited sensitivity. To overcome this limitation, we theoretically propose a novel guided-wave SPR (GWSPR) configuration coated with a few-layer blue phosphorene (blueP)/MoS2 hybrid structure. This configuration aims to enhance the electric field and subsequently achieve a significant improvement in sensitivity. The results of our study demonstrate that the proposed blueP/MoS2-based GWSPR sensor exhibits a high sensitivity of 290°/RIU, which represents an impressive enhancement of approximately 82.4% compared to the conventional Au-based SPR sensor. This advancement addresses the challenge of detecting ultralow changes in refractive index and offers significant potential for enhancing the performance of chemical and biological sensors.