In the present study, we conducted propeller open water test, resistance test, and propeller, ship hull interaction for a ship‟s resistance and propulsion performance, using computational fluid dynamics techniques, where a K-epsilon, K-omega turbulence viscous models were employed. For convenience of mesh generation, unstructured meshes were used in the propeller region of a ship, where the hull shape is formed of delicate curved surfaces. On the other hand, structured meshes were generated for the remaining part of the hull and its domain, i.e., the region of relatively simple geometry. To facilitate the rotating propeller for propeller a moving reference frame motion type technique was adopted. The computational results were validated by comparing with the existing experimental data. In this work we are interested in predicting the frictional resistance offered to a ship during is motion. To this effect we start off with a consideration of the resistance offered to the bare hull in the absence of the propeller and later extend to the case where the propeller is in-place. The thrust generated by the propeller alone without considering the ship (called open water analysis) is also performed using CFD. FLUENT 6.0®, was used for CFD analysis and for modeling and meshing the packages used are CATIA – V5® and ICEM-CFD® respectively. The open water analysis of the 4-bladed propeller predicted a thrust of 346 kN at 30 rps. The bare hull resistance at 228 kN at 18 m/s, and resistance with propeller in place at 18 m/s was found to be 245 kN. The results predicted by the CFD analysis were found to be suitable for the present HSDS and it is believed that the hydrodynamics design of the propeller is acceptable for the problem at hand.