Results of a gravity and magnetic study over a lava field in the southern Basin of Mexico are used to investigate on lava emplacement and pre-eruptive topography. The characteristics of lava flows depend on multiple factors, including the lava composition, effusion rate, rheology, fluid content and underlying terrain. The ∼2000 years old volcanic field, formed by seven flow units emplaced by the Xitle eruption, covers an extensive area >80 km2 characterized by topographic relief on the Ajusco volcano flank and surrounding plain. The study is conducted on the northern end of the volcanic field. The gravity and magnetic study is based on regional-residual separation, vertical and horizontal derivatives, reduced to the pole, analytical signal, spectral analysis and forward modeling. The regional gravity field shows two anomaly lows in the central sector, with the residual field showing trends of gravity highs. The residual magnetic anomaly is characterized by trends of magnetic highs associated to the lava field. Depths estimated from spectral analysis of gravity and magnetic anomalies show shallow sources at ∼22 m and ∼46 m, and deep sources at ∼469 m and ∼268 m, respectively. The underground sequence is modeled as a volcanoclastic succession of varying thickness. The first vertical derivatives, gradients and analytical signal enhance the anomalies associated to lava thickness variations. Joint gravity and magnetic analysis constraints the deep/shallow anomaly sources in the volcanic field and relations to pre-eruptive structure.