Research Expertise Research Articles

The centre for health informatics: a novel approach to accelerating the field of health data science

Precision Medicine and Precision Public Health are approaches to improve population health. Achieving these goals requires innovation in health informatics. The Centre for Health Informatics (CHI) within the Cumming School of Medicine (CSM) at the University of Calgary (UC), Canada, was created to respond to this need by fostering multidisciplinary collaborations, building capacity by recruiting and training outstanding faculty and students, and harnessing Alberta's rich health data to advance health informatics. To establish CHI as a health informatics leader, CHI has struck partnerships with stakeholders, including Alberta Health Services (AHS), Alberta Health (AH), and the Alberta Strategy for Patient-Oriented Research Unit (AbSPORU) among others. Through these close relationships, the CHI intake team facilitates access to Alberta's rich health data sources and educates researchers on the available health data in Alberta. The concept of a "One Stop Shop" for CSM and UC researchers encourages multidisciplinary collaboration, helps investigators access a wide range of datasets, and receive analytical support. Population-based data sets enable the development of methods to turn raw data into health information, improve health data collection, linkage, analysis, and quality, and applied studies creating clinical decision-support tools, prognostic tools, improved health surveillance methods, and health system performance indicators. CHI's ecosystem of diverse research expertise, cutting-edge technology, and embedded AHS analysts to support data access via a wide-ranging network of partnerships allows our provincial researchers, national and international collaborators tremendous opportunities for empirical research. It paves the way for implementing Precision Medicine in the real world.

Equity and inclusivity in the faculty ranks: Our experience with a clinical track

BackgroundThe evolution of nursing education requires a combination of strong academic faculty and expert clinicians. Different professional growth and development pathways are necessary to build a robust faculty with clinical and research expertise. Some schools have implemented a formal clinical track (CT) to complement the traditional tenure track for the professional advancement of CT. MethodsThe article presents a case example of how one institution maintains and advances a strong CT using the Kotter Change Model and discusses future directions. ResultsThe school's infrastructure for promotion, which follows a similar structure and guidelines as Tenure Track (TT) Promotion and Tenure Guidelines, has led to an increase in the school's scholarly productivity among CT faculty across ranks. Increasing poster and podium presentations as well as publications to a national and international audience results in greater reach and improved reputation for the school, both nationally and internationally. ConclusionsWhile there is still work to be done to advance equity and inclusion for nursing CTs, developing and maintaining a CT with system-level structures holds significant value and provides a clear path to promotion, invests in clinical scholarship, and includes clinical faculty as full citizens in academia.

Diagnostic and Prognostic Value of Hyperammonemia in Patients with Liver Cirrhosis, Hepatic Encephalopathy, and Sarcopenia (Experts’ Agreement)

Introduction. In cirrhotic patients, hyperammonemia develops due to impaired ammonia detoxification and portosystemic blood shunting and is most commonly associated with hepatic encephalopathy and sarcopenia. Currently, there are questions regarding the diagnosis of hyperammonemia and the effect of ammonia-lowering therapy on disease outcomes.Materials and methods. The Russian Scientific Liver Society selected a panel of seven experts in liver cirrhosis research and management of patients with this disease to make reasoned statements and recommendations on the issue of diagnostic and prognostic value of hyperammonemia in patients with liver cirrhosis, hepatic encephalopathy and sarcopenia.Results. The Delphi panel identified the most relevant topics, in the form of PICO questions (patient or population, intervention, comparison, outcome). The Delphi panel made six questions relevant to clinical practice and gave reasoned answers, framed as ‘clinical practice recommendations and statements’ with evidence-based comments. The questions and statements were based on the search and critical analysis of medical literature by keywords in Englishand Russian-language databases. The formulated questions could be combined into four categories: hepatic encephalopathy, sarcopenia, hyperammonemia, and ammonia-lowering therapy.Conclusions. The results of the experts' work are directly relevant to the quality management of patients with liver cirrhosis, and their recommendations and statements can be used in clinical practice.

The Challenges and Opportunities of Teaching EFL in Revolution 4.0 Era

This research aims to investigate the challenges and opportunities to teach English in the fourth industrial revolution, and improved the researcher's understanding and expertise about teaching English in the 4.0 industry revolution and researched issues educators face while teaching English of EFL. This study using qualitative method. 3 Englsih teachers as the participants in this research from level of school SD/MI, SMP/MTs, SMA/K/MA especially in BBC Tlogosari. Interviews and questionnaires were used as collecting data techniques. Twenty questions from the questionnaires were used, and three questions from the interview were about the opportunities and difficulties of teaching EFL in the context of Revolution 4.0. In addition, difficulties in the process of teaching and learning exist, especially with modern technology and more innovation. Mostly students will access the internet without assistance, which will have positive or even negative impact, for this reason the role and strategy of educators and facilitators is important.

Digital Futures of Learning Pharmacology and Medicinal and Organic Chemistry.

Traditional pharmacology and medicinal and organic chemistry teaching often rely on the trusted textbook visuals. However, students may struggle to grasp mechanisms that appear too complex. Because the pandemic has mandated the majority of educators to use new techniques and innovative technology in their communication approaches with students, we offer several digital strategies for educators to explore and/or to enhance student learning. These technology-infused strategies are drawn from our cross-country (Singapore and France) teaching and research experiences and expertise.

Operational tolerance research in liver transplantation: a bibliometric analysis using a new web resource.

Operational tolerance in liver transplantation (OT-LT), defined as the graft survival with normal function in absence of immunosuppression, has been a field of intense research since the 1980s. Thereafter, tens of clinical trials and hundreds of articles have been published, making it challenging for researchers to assimilate all the information, more so outside of their disciplines. The aim of the present study was to analyze the research in OT-LT through a new web tool (https://tolerance.imib.es). We have developed a web resource that allowed the identification of the present trends and potential research avenues in OL-LT, an overview biomedical terms that were most often cited, including which journals published the most articles, and an advanced search engine that exploited all the information in these publications. A total of 734 studies were analyzed until November 2023, with a mean of 15 articles published per year, a total sum of 3,751 impact factor points and a total of 26,542 citations. The analysis of citations allowed us to establish a ranking of the most prolific countries, authors, journals and institutions, in addition to the most influential publications in OT-LT. Likewise, keyword and co-occurrence analyses answered which themes involving OT-LT are the most popular, whereas cooperation analysis showed that principal authors in OT-LT form a network, although the lack of international cooperation, especially with regard to clinical trials, appears to be one of the main challenges. Despite its limitations, our web tool will allow both OT-LT expert and novel researchers to be able to draw a comprehensive picture of the past, present and future of OT-LT research.

Establishing an updated consensus on the conceptual and operational definitions of Making Every Contact Count (MECC) across experts within research and practice: an international Delphi Study

ObjectivesThe Making Every Contact Count (MECC) initiative is broadly defined as an opportunistic approach to prevention by making use of the thousands of conversations service providers have with service users every day. However, since its conception, the application of MECC has diverged and developed considerably. Thus, the current study aimed to revise the definition according to current research and practice to better describe what is and is not included. Study designA consensus building classic Delphi methodology, completed by an expert panel. MethodsRound 1 asked open questions around the definition of MECC. Content analysis of round 1 identified statements that were rated for agreement in round 2. Statements achieving ≥80% agreement were included in a short, long, or operational definition of MECC that were rated for agreement in round 3 (the minimum number required). An agreement of ≥80% indicated consensus. ResultsForty out of 100 contacted experts completed three rounds. Experts in practice and research were recruited internationally although most were from England. From round 1, 274 statements were generated, of which 96 achieved consensus and were included within round 3. The short and long definition received consensus in round 3, the operational definition required four rounds to reach consensus. ConclusionsMECC is a person-centred approach to health behaviour change that, provided an individual possesses the relevant skills, can be delivered by anyone and anywhere. The distinguishing feature of MECC is not in its duration, target behaviour, or conditions for delivery, but rather in the approach taken and the mechanisms applied to conversations. Implications for research and practice are discussed, and the limits for applicability acknowledged.

The use of computed tomography and X-ray fluorescence analysis in the research of printed book from the seventeenth century: book binding, tomographic reading of the text, dendrochronological dating, pigments analysis

This paper presents the use of X-ray computed tomography and X-ray fluorescence in the analysis and expert research of the seventeenth century printed book "Eukhologīon albo Molitoslov, ili Trebnik" from Kiev. The main purpose of the survey was to confirm whether the book binding is original or whether it is a rebinding, and whether there are any fragments of the hidden older texts. Commonly used radiography is usually not able to provide sufficient information for these purposes. On the other hand, computed tomography allows a detailed and three-dimensional documentation of the bookbinding technology and the structure of the materials used, including the wooden boards. It will be presented that all elements of the weave are clearly visible, making it possible to show that there are no internal defects in the stitching and materials. It has also been convincingly shown that there are no fragments or layers of older texts in the binding, so no further invasive intervention will be necessary regarding this aspect. The paper also demonstrates the possibility of reading the text in a closed book utilising X-ray computed tomography data; this option may be advantageous for massively damaged manuscripts. It will also be shown, that thanks to detailed tomographic imaging of the wood structure of the boards, a dendrochronological survey can be successfully carried out without invasive intervention into their outer layers. From the CT data it was also found that the pigments of the letters have significantly different densities. Therefore, as part of the survey, elemental analysis of the writing was also carried out using a portable X-ray fluorescence spectrometer to confirm and clarify this finding.

Virtual reality as a tool to enhance the efficiency and reliability of the virtual reconstruction process for heritage/archaeological sites: The case of umm Al-Jimal in Jordan

The growing attention towards reconstruction, driven by its potential to promote sustainable heritage preservation, is impacted by a shortage of the data, sources, and interpretive methods employed in virtual reconstruction. Consequently, the public (individuals and reviewers/Professionals) faces challenges in determining between the original elements and the added elements, in addition to identifying the origin of the new elements. Despite researchers' efforts to implement virtual reality as a solution, its effectiveness is constrained to the end outcome due to the lack of integration of reconstruction information. A set of factors contribute to the challenge of incorporating interactive information into virtual reality, including the researcher's expertise in virtual reality software and the deterministic nature of the C programming language. This necessitates the development of more user-friendly methods to support researchers in reducing the shortage and limitations. As a result, the study aims to develop a method for simplifying the process of transferring virtual reconstruction operations to virtual reality and test its efficiency through interviews with individuals and reviewers/Professionals. This is accomplished through the integration of virtual reconstruction steps with the Unreal Engine program, which serves as a virtual reality platform and is easier to program than Unity which is more prevalent in heritage research. The findings delivered a more efficient approach to collecting diverse sources and integrating them into one platform simply. This approach also facilitates direct communication between reviewers/Professionals and researchers, thereby enhancing the efficiency of the reconstruction peer review process. Furthermore, the utilization of virtual reality has played an important role in enhancing comprehension between what is the origin and added, as well as facilitating the validation of the rebuilding procedure among individuals and reviewers/Professionals.

Recruitment, Retention, and Training of Citizen Scientists in Translational Medicine Research: A Citizen Science Initiative on Non-Alcoholic Fatty Liver Disease.

Citizen science is a participatory science approach in which members of the public (citizens) collaborate with scientists and professional researchers and become involved in research and innovation activities, resulting in the co-creation of scientific knowledge and innovation. Citizen science has been widely applied in research, particularly in the social sciences, environmental sciences, information and communication technologies, and public health. However, the application of this approach inclinical sciences, particularly in translational medicine research, is still nascent. This exploratory study involved members of the public (citizen scientists) in a translational medicineexperiment on non-alcoholic fatty liver disease that incorporated a lifestyle and weight-loss intervention. The aim of this paper is to report successful methods and approaches for the recruitment, retention, and training of citizen scientists. For the citizen scientists' recruitment, online calls placed on the websites of our research project and biomedical research centerand targeted emails were the most helpful. Of the 14 members of the public who expressed interest in our study, six were recruited as citizen scientists. Citizen scientists were mostly female (n = 5, 83%), white (n = 3, 50%), over 50 years of age (n = 4, 67%), educated to postgraduate level (n = 5, 83%), and either retired or not in employment (n = 5, 83%). The retention rate was 83% (n = 5), and the dropout rate was 17% (n = 1). We arranged instructor-led interactive online training sessions (an hour-long one-on-one session and two-hour group sessions). Research skills training covered ethics in research and qualitative and quantitative data analysis. Citizen scientists were given several incentives, such as reimbursement of travel and care costs, selection as citizen scientists of the month, publications of their blogs and perspective articles, and co-authorship and acknowledgement in papers and project deliverables. To conclude, members of the public (particularly middle-aged white women with postgraduate education) are interested in becoming citizen scientists in translational medicine research. Their retention rate is higher, and they can contribute to different research activities. However, they need training to develop their research skills and expertise. The training should be simple, comprehensive, and flexible to accommodate the schedules of individual citizen scientists. They deserve incentives as they work on a voluntary basis.

Capacity of community health centers to treat snakebite envenoming in indigenous territories of the Brazilian Amazon

IntroductionThe deaths from and morbidities associated with snakebites - amputations, loss of function in the limb, visible scarring or tissue damage - have a vast economic, social, and psychological impact on indigenous communities in the Brazilian Amazon, especially children, and represent a real and pressing health crisis in this population. Snakebite clinical and research experts have therefore proposed expanding antivenom access from only hospitals to include the community health centers (CHC) located near and within indigenous communities. However, there are no studies examining the capacity of CHCs to store, administer, and manage antivenom treatment. In response to this gap, the research team calling for antivenom decentralization developed and validated an expert-based checklist outlining the minimum requirements for a CHC to provide antivenom. MethodsThe objective of this study was thus to survey a sample of CHCs in indigenous territories and evaluate their capacity to provide antivenom treatment according to this accredited checklist. The checklist was administered to nurses and doctors from 16 CHCs, two per indigenous district in Amazonas/Roraima states. ResultsOur results can be conceptualized into three central findings: 1) most CHCs have the capacity to provide antivenom treatment, 2) challenges to capacity are human resources and specialized items, and 3) antivenom decentralization is feasible and appropriate in indigenous communities. ConclusionDecentralization would provide culturally and contextually appropriate care accessibility to a historically marginalized and underserved population of the Brazilian Amazon. Future studies should examine optimal resource allocation in indigenous territories and develop an implementation strategy in partnership with indigenous leaders. Beyond the indigenous population, the checklist utilized could be applied to community health centers treating the general population and/or adapted to other low-resource settings.

Competency in evidence-based medicine and associated factors among medical radiology technologists in Addis Ababa, Ethiopia.

Evidence-based medicine integrates clinical expertise, patient values and best research evidence in clinical decision-making. This study aimed to assess evidence-based medicine knowledge, attitudes, practices and associated factors among medical radiology technologists in Addis Ababa, Ethiopia. A cross-sectional study was conducted among 392 medical radiology technologists from May to August 2022 using a self-administered questionnaire. Bivariate and multivariate logistic regression identified factors associated with evidence-based medicine practice. Most medical radiology technologists (57.7%) had moderate evidence-based medicine knowledge and 94.9% had favourable attitudes. However, 64.8% demonstrated poor evidence-based medicine practice. Factors significantly associated with better evidence-based medicine practice were moderate knowledge (AOR 1.949, 95% CI 1.155-3.291), good statistical understanding (AOR 1.824, 95% CI 1.135-2.930), sufficient time for evidence-based medicine (AOR 1.892, 95% CI 1.140-3.141), institutional support (AOR 2.093, 95% CI 1.271-3.440) and evidence-based medicine resource access (AOR 1.653, 95% CI 1.028-2.656). Despite moderate knowledge and positive attitudes towards evidence-based medicine, most medical radiology technologists had suboptimal utilisation. Strategies to improve knowledge, ensure dedicated time, provide institutional support and resources could enhance evidence-based radiology practice.

Conveying the pathogenesis of type 1 diabetes to the blind, low-vision and diverse needs communities through sensory stimulation.

To educate members of the blind, low-vision and diverse needs communities on the pathogenesis of the chronic autoimmune disease, type 1 diabetes, members of our team with research expertise in immune-mediated diseases, participated in the 2023 Monash Sensory Science (MSS) Exhibition. Using QR code linked audio commentary, participants were guided through tactile displays demonstrating normal insulin action in the regulation of blood glucose levels and its vital role in providing energy to tissues, followed by displays describing the various stages of the immune system's aberrant attack and the eventual complete destruction of the insulin producing beta-cells of the pancreatic islets in type 1 diabetes. These models conveyed to the participants the huge effect that this autoimmune-mediated disease has on the quality of life of affected individuals including the subsequent lifelong reliance on insulin injections to maintain glucose homeostasis. This MSS Exhibition provided a unique opportunity for our researchers to engage with under-represented members of the community and to raise awareness about such a debilitating and common autoimmune disease.

Prospectively accelerated dynamic speech magnetic resonance imaging at 3 T using a self-navigated spiral-based manifold regularized scheme.

This work develops and evaluates a self-navigated variable density spiral (VDS)-based manifold regularization scheme to prospectively improve dynamic speech magnetic resonance imaging (MRI) at 3 T. Short readout duration spirals (1.3-ms long) were used to minimize sensitivity to off-resonance. A custom 16-channel speech coil was used for improved parallel imaging of vocal tract structures. The manifold model leveraged similarities between frames sharing similar vocal tract postures without explicit motion binning. The self-navigating capability of VDS was leveraged to learn the Laplacian structure of the manifold. Reconstruction was posed as a sensitivity-encoding-based nonlocal soft-weighted temporal regularization scheme. Our approach was compared with view-sharing, low-rank, temporal finite difference, extra dimension-based sparsity reconstruction constraints. Undersampling experiments were conducted on five volunteers performing repetitive and arbitrary speaking tasks at different speaking rates. Quantitative evaluation in terms of mean square error over moving edges was performed in a retrospective undersampling experiment on one volunteer. For prospective undersampling, blinded image quality evaluation in the categories of alias artifacts, spatial blurring, and temporal blurring was performed by three experts in voice research. Region of interest analysis at articulator boundaries was performed in both experiments to assess articulatory motion. Improved performance with manifold reconstruction constraints was observed over existing constraints. With prospective undersampling, a spatial resolution of 2.4 × 2.4 mm2/pixel and a temporal resolution of 17.4 ms/frame for single-slice imaging, and 52.2 ms/frame for concurrent three-slice imaging, were achieved. We demonstrated implicit motion binning by analyzing the mechanics of the Laplacian matrix. Manifold regularization demonstrated superior image quality scores in reducing spatial and temporal blurring compared with all other reconstruction constraints. While it exhibited faint (nonsignificant) alias artifacts that were similar to temporal finite difference, it provided statistically significant improvements compared with the other constraints. In conclusion, the self-navigated manifold regularized scheme enabled robust high spatiotemporal resolution dynamic speech MRI at 3 T.

Rapid design for large-scale parallel CFRP cable with multi-source experimental data

With advancements in material properties and reduced costs, carbon fibre reinforced polymer (CFRP) cables are gaining popularity in engineering applications due to their superior strength-to-mass ratio and durability. However, the tensile strength of large-scale parallel CFRP cables remains a critical issue, warranting further research and engineering expertise. To address this issue, this paper proposes a method to rapidly predict and adaptively correct the tensile strength of large-scale parallel CFRP cables using multi-source experimental data and an integrated approach that incorporates Monte Carlo simulations, Neural Network algorithms, and Genetic algorithms. This comprehensive method takes into account the influence of various factors including small-scale material strength and its coefficient of variation, cable length, the number of parallel wires, installation errors, and anchorage errors. Validated by reported experimental data, the method demonstrates its effectiveness in accurately predicting the tensile strength of parallel CFRP cables. Moreover, a design method for large-scale parallel CFRP cables is proposed based on the reliability theory. Lastly, the efficiency and effectiveness of the proposed method are validated through the design and optimization of a cable-stayed bridge featuring a main span of 1984 m, utilising both parallel steel and CFRP cables.

Analysis of Victims' Attitude and Isolation from Sexual Harassment among Athletes in South-South State Sports Councils of Nigeria

This study was designed to determine the Prevalence and Determinants of Sexual Harassment Among Athletes in South-South States Sports Council in Nigeria. Two specific objectives, two research questions and two null hypotheses guided the study. The study adopted descriptive survey design. The population for the study comprised of 1,647 male and 1,274 female athletes. They give a total of 2,921 sports athletes in South-South Sports Council which spread across the six states. The sample size of the study consisted of 336 male and 262 female athletes giving a total of 598 representing 20% of athletes from each of the state Sport Council. Instrument titled “Victims Attitude and Isolation as a determinant of Sexual Harassment of Athletes Questionnaire (VAIDSHAQ)” was used for data collection. The instrument was validated by three research experts, all from the University of Uyo. Instrument was trial tested on 20 athletes who were not part of the research sample. Cronbach Alpha Reliability Statistics and reliability co-efficient of 0.98 was obtained. The data was analysed using simple regression to answer research questionswhile the hypothesis was tested using F-ratio in simple linear regressionat .05 levels of significance. The prevalence of victim attitudes and isolations from sexual partners are determined of sexual harassments among athletes. Based on the findings of the study, it is recommended among measures that individuals with records of sexual abuse should not be admitted into the sport council in order to avoid repetition of such act. Also, that victims of sexual harassment who refuse to report the incidence should be sanctioned by the sport council when noticed.

An ode to multidisciplinarity: the 'Bacteria Orchestrate Life' international meeting.

If scientists stick to their research expertise without collaborating with other experts in different fields, it could stall the progress of their work in a world where interdisciplinary thinking and working should be second nature. Biologists are at the forefront of this trend. That is why a consortium formed by the faculty of sciences of Tunis El Manar University, Tunisia, the GetGenome Foundation and Learn and Win, decided to organise an international conference on bacteria, a perfect field for multidisciplinarity. For 3 days, from 14 to 16 December 2023, more than 200 interdisciplinary researchers and students of life sciences and more than 20 international speakers and trainers met at the faculty of sciences in Tunis, to discuss microbiology and bacteria from different horizons, from the most fundamental to the most imaginative, with a strong focus on technologies and discoveries. This Meeting Review describes the scientific event and highlights the main results of both the conferences and the practical sessions.

Neglected tracts of the brainstem: transverse peduncular tract of Gudden and taenia pontis.

The anatomy and function of the brainstem have fascinated scientists for centuries; however, the brainstem remains one of the least studied regions of the human brain. As the authors delved into studying this structure, they observed a growing tendency to forget or neglect previously identified structures. The aim of this study was to describe two such structures: the transverse peduncular tract, also known as the Gudden tract, and the taenia pontis. The authors analyzed the potential effects of neglecting these structures during brainstem surgery and the implications for clinical practice. After removal of the arachnoid and vascular structures, 20 human brainstem specimens were frozen and stored at -16°C for 2 weeks, according to the method described by Klingler. The specimens were then thawed and dissected with microsurgical techniques. The results of microsurgical fiber dissection at each step were photographed. This study revealed two previously neglected or forgotten structures within the brainstem. The first is the transverse peduncular tract of Gudden, which arises from the brachium of the superior colliculus. This tract follows an arcuate course along the lateral and ventral surfaces of the midbrain, perpendicular to the cerebral peduncle, and terminates in the nuclei of the transverse peduncular tract within the interpeduncular fossa. The second structure is the taenia pontis, which originates contralaterally in the interpeduncular fossa. It becomes visible at the level of the pontomesencephalic sulcus and extends to the base of the lateral mesencephalic sulcus, where it divides into several thin bundles. Along the interpeduncular sulcus, between the superior and middle cerebellar peduncles, it reaches the parabrachial recess and enters the cerebellum. Recently, with increasing understanding and expertise in brainstem research, surgical approaches to this area have become more common, emphasizing the importance of a detailed knowledge of the brainstem. The two structures mentioned in this paper are described in history books and were widely studied in the 19th century but have not been mentioned in modern literature. The authors propose that a deeper understanding of these structures may prove valuable in neurosurgical practice and help reduce patient comorbidity.

A Matlab-based application for quantification of yeast cell growth on solid media.

Quantitative assessment of growth and survival is a suitable technique in studying biochemical, genetic and physiological processes in the cells. The budding yeast Saccharomyces cerevisiae is one of the most widely used eukaryotic model organisms for studying cellular mechanisms and processes in evolutionarily distant species, including humans. Yeast growth can be evaluated on both liquid and solid media by measuring cell suspension turbidity and colony forming units, respectively. Several software tools utilizing different parameters have been proposed to quantify yeast growth on solid media. Here, we developed a Matlab-based application which provides a rapid and robust quantitative yeast growth analysis from spot plating assay. Spot plating assay is a typical procedure to evaluate yeast growth in low-throughput laboratory settings, including growth on different nutrient sources or treatment with specific stressors. The app has a one-step installation process, a self-explanatory interface and shorter analysis steps compared with previous established methods, providing a useful tool for both expert and non-expert yeast researchers.

Expert consensus on perioperative integrated skincare for noninvasive energy-based device aesthetic procedures in clinical practice in China.

Noninvasive energy-based device (NI-EBD) aesthetic procedures has recently gained widespread usage for treating various skin conditions, enhancing skin texture and performing rejuvenation-related procedures. However, practically all NI-EBD procedures result in variable degrees of damage to the skin barrier, inducing pathological and physiological processes such as oxidative stress and inflammation, and only a small percentage of individuals possess the innate ability to restore it. To introduce the concept of integrated skincare and establish standardized operational procedures for perioperative integrated skincare, and furnish a theoretical basis for clinical diagnosis and treatment performed by professional medical aestheticians. The author leveraged domestic and international guidelines, clinical practice expertise and evidence-based research, adapting them to suit the specific circumstances in China. The consensus were provided four parts, including concept and essence of integrated skincare, integrated skincare significance during the perioperative phase of NI-EBD procedures, active ingredients and functions of effective skincare products, standardized perioperative skincare procedure for NI-EBD procedures and precautions. For the standardized perioperative skincare procedure, four recommendations were listed according to different stages during NI-EBD procedures. These recommendations create the 'Expert Consensus on Perioperative Integrated Skincare for Noninvasive Energy-Based Device Aesthetic Procedures in Clinical Practice in China'.