Aim: The aim of this study is to investigate the measurement of landscape integrity based on ecological support processes in the Federal District, with the aim of defining a multi-scalar and multi-functional Regional Green Infrastructure Network (IVR) based on Nature-Based Solutions (NBS). Theoretical Framework: This topic presents the main concepts and theories that underpin the research. Landscape Ecology, Restoration Ecology, Green Infrastructure and Geodesign stand out, providing a solid basis for understanding the research context. Method: The methodology adopted for this research comprises the analysis of ecological support processes in the landscape, using the multispectral “CO2flux” index, related to the photosynthetic efficiency of vegetation and a proxy for energy, carbon and biomass inputs, which, together with the “Topographic Wetness Index”, related to the flow and accumulation of water and sediment in the landscape, provided the basis for the elaboration of a Geodesign process. Data was collected using multispectral satellite scenes - “Landsat 8”, collected during the dry season. Results and Discussion: The results obtained revealed the design of a mosaic of “hotspots”, corridors and patches that consolidates and intensifies carbon flows in the Federal District's landscape, with positive impacts on territorial resilience. In the discussion section, these results are contextualized in the light of the theoretical framework, highlighting the implications and relationships identified. Possible discrepancies and limitations of the study are also considered in this section. Research Implications: The practical and theoretical implications of this research are discussed, providing “insights” into how the results can be applied, or how to influence practices in the field of landscape planning. These implications can cover the design of Nature-Based Solutions at a regional scale, climate mitigation and adaptation actions for territories, and people's access to ecosystem services. Originality/Value: This study contributes to the literature by proposing the design of a regional network of green infrastructures based on the analysis of the flow of ecological support processes in the landscape, considering different demands and goals for environmental recovery. The relevance and value of this research is evidenced by the possibility of planning and designing mosaics in the landscape based on the identification of networks with greater potential for the provision of ecosystem services and, consequently, for the adaptation and mitigation of territories to climate impacts and those resulting from human occupation.