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Contrastive Analysis of Tabe Politeness Speech Acts in Bugis and Sumimasen in Japanese (Pragmatic Study)

This research investigates the level of politeness exhibited by Tabe in Bugis and Sumimasen in Japanese. The researchers do a contrastive analysis to examine the differences and similarities between Tabe in Bugis and Sumimasen in Japanese, which encompasses the act of begging and the pragmatic aspect of politeness. This research uses a contrastive descriptive qualitative methodology, in which the data consists of elaborate qualitative information rather than numerical values. This data is examined by using two distinct approaches, specifically descriptive and contrastive data analysis. The findings of this investigation in the term "tabe" holds significant symbolism in Bugis language and culture, serving as a means to kindly and respectfully request permission. By strategic use of "tabe" in appropriate circumstances, individuals can demonstrate profound gratitude and courtesy towards others, enhance social connections, and uphold societal harmony. Likewise, the use of "sumimasen" in Japan underscores cultural principles that emphasize courtesy, modesty, and social concord. The word is employed in several contexts to apologise, request assistance, or convey appreciation, and serves to sustain positive relationships and prevent conflict in daily contacts.

The Reasons and Influence of the Establishment of One Port Trade System in Guangzhou during Qing Dynasty

Guangzhou is located in the southern part of China, near the South China Sea, belongs to Guangdong Province. It serves as China's southern gateway to the world and was historically called "The Southern Treasure of the Emperor", playing a crucial role in China's maritime trade history. Throughout Chinese history, Guangzhou underwent several cycles of "closure" and "opening", policies that severely impacted trade. However, foreign merchants never ceased to request permission from the Chinese government to engage in trade. In 1757, Emperor Qianlong decreed Guangzhou as the only one official port for foreign trade. This edict led to the establishment of the one port trading system in Guangzhou, as the Qing government aimed to counter foreign influences and local uprisings while maintaining a self-sufficient small-scale agricultural economy. Western nations and their traders sought opportunities within this system, aspiring to expand trade to other regions of China, even the inland areas. The exclusive status of Guangzhou as China's only one trading port persisted until 1842, following the defeat of the Qing government in the Opium War against Britain, the Nanjing Treaty was signed. This treaty opened Guangzhou, Shanghai, Ningbo, Fuzhou, and Xiamen as trading ports, bringing an end to the one port trading system. The reasons and impacts of the establishment of this system have not been comprehensively analyzed to date. Therefore, this paper based on historical archives, analyzes both the direct and underlying reasons behind Emperor Qianlong's decision and elucidates the system's diverse impacts on various aspects of Qing-era China.

Should employees be entitled to legal representation during disciplinary hearings in South Africa?

This article demonstrates that employees in South Africa are denied the right to appoint external legal representation of their own choice during disciplinary inquiries. It argues that this violates their fundamental rights such as dignity, fair labour practice, and practicing their chosen occupation freely. Although Item 4(1) of Schedule 8 of the Code of Good Practice: Dismissal allows accused employees the opportunity to be represented by a trade union representative or a fellow employee, this Code is silent on whether an accused employee can obtain external legal representation of their choice during disciplinary inquiries. It further illustrates that accused employees who are brought before disciplinary hearings are placed in a position where they are forced to rely on their fellow employees or trade union officials who may not possess the skills and competency to adequately present their defences. Further, if they wish to seek external legal representation, they need to request permission from chairpersons of disciplinary hearings who usually refuse to grant such permission. This article advances an argument that it is constitutionally impermissible to adopt a paternalistic approach where dismissal is a likely sanction to subject accused employees to the discretion of chairpersons of disciplinary inquiries to decide whether to allow external legal representation. It argues further that accused employees should have a right to decide for themselves whether to obtain external legal representation of their own choice during disciplinary hearings.

Influence of work motivation on the performance of employees in a public company

The objective of this research is to know if there is an influence of work motivation on the performance of its workers. An investigation was carried out on the concepts related to the subject of study, in which indications are reported that there is no motivation towards employees, which generates low performance. The importance of carrying out the study, the beneficiaries and the impact it could have for future research are mentioned. The research presented is of a quantitative type with a cross-sectional design and an instrument was applied through a non-probabilistic sampling for convenience to the company. The procedure that was carried out to obtain results was to request permission and authorization from the organization. Subsequently, a survey was applied in Google Forms to 100 collaborators, sent by WhatsApp. With SPSS, α and graphs of results were obtained; the most significant questions were: Do you instruct the trained personnel in the new processes? (70% agree), (23% disagree) and (7% indifferent); Does the pension they receive grant security in the future (60% agree), (23% disagree) and (17% indifferent). In conclusion, the company under study shows favorable results and can improve its organizational culture.

Current ethical dilemmas in obstetrical practice and some suggestions regarding how to resolve them

As new ethical conundrums arise in obstetrics, providers are ever-increasingly challenged with having to know the best means of resolving these problems since Roe v. Wade was overturned. New ethical challenges have arisen, for example, as to how clinicians should respond when patients would need to travel to another state to get an abortion. A second illustrative example involves minors. In some states in the U.S., these patients legally can request permission from a judge to have an abortion without their having to tell their parents. If these adolescents don’t know this, providers must decide whether they should take initiative to inform them of this possibility and if so, when. This question is still more challenging when these patients, too, live in a state that does not allow them the option of abortion. Providers confronted with ethical problems such as those above may struggle to determine how to best resolve these dilemmas. This piece will review some key and especially more subtle, ethical approaches that providers may face to better resolve them. Initially, I will highlight approaches to resolving ethical outcomes that providers may not know or may overlook. These will include how providers may best apply both core ethical principles and an additional, adjunctive framework, known as the care perspective or ethics of care. I will provide specific examples to illustrate each

INSTITUTIONALIZATION OF LOCAL WISDOM WEDDING PROCESSES IN CULTURE OF PUSAR VILLAGE, BATURAJA SUB-DISTRICT OGAN KOMERING ULU DISTRICT

Culture is a knowledge system that includes a system of ideas contained in the human mind, so that in everyday life culture is abstract. The wedding procession with sacrifice, the slaughter of a scapegoat for the people of Pusar Village is one of the traditions owned by the people of Pusar Village, Baturaja District. The approach used in the meaning of verbal and nonverbal communication in a series of marriage processions with sacrifices, the slaughter of scapegoats uses symbolic interaction theory, symbolic interaction theory holds that individuals form the same meaning through communication. The method used is descriptive qualitative method. In collecting data, conducting in-depth interviews (Depth Interview) to key informants, the selected informants are people who are considered to know and understand the problems studied. The results of the analysis in this study are marriage processions with sacrifices, slaughtering scapegoats in Pusar Village there are forms of verbal communication and nonverbal communication contained in every series of marriage processions with sacrifices, slaughtering scapegoats including prayer. The prayer delivered by the traditional leader and followed by the family holding a wedding ceremony aims to request permission to hold a wedding ceremony and share happiness with the ancestors. After taking turns praying, the family waters the graves of their ancestors with the water that has been provided. From the results of the research conducted, it can be concluded that in every series of wedding processions with sacrifices, the slaughter of a scapegoat has a meaning that has been believed by the people of Pusar Village itself. It is hoped that the people of OKU Regency can participate in preserving the existing culture and arts. Especially in the cultural arts of the wedding procession with sacrifice, the slaughter of this scapegoat.

Shavian Perspectives on the Cusp of Change and War (Pygmalion, Heartbreak House, and St. Joan)

Shavian Perspectives on the Cusp of Change and War (Pygmalion, Heartbreak House, <i>and</i> St. Joan)

A phase 2 prospective study of bortezomib, cyclophosphamide, and dexamethasone in patients with newly diagnosed iMCD

Letter| March 16, 2023 A phase 2 prospective study of bortezomib, cyclophosphamide, and dexamethasone in newly-diagnosed iMCD patients Hao Zhao, Hao Zhao Peking Union Medical College Hospital, Beijing, China https://orcid.org/0000-0003-0736-9700 Search for other works by this author on: This Site PubMed Google Scholar Miao-yan Zhang, Miao-yan Zhang Peking Union Medical College Hospital, Beijing, China Search for other works by this author on: This Site PubMed Google Scholar Kai-ni Shen, Kai-ni Shen Peking Union Medical College Hospital, Beijing, China Search for other works by this author on: This Site PubMed Google Scholar Jun Feng, Jun Feng Peking Union Medical College Hospital, Beijing, Florida, China Search for other works by this author on: This Site PubMed Google Scholar Xin-xin Cao, Xin-xin Cao Peking Union Medical College Hospital, Beijing, China Search for other works by this author on: This Site PubMed Google Scholar Ming-hui Duan, Ming-hui Duan Peking Union Medical College Hospital, Beijing, China https://orcid.org/0000-0003-2130-6300 Search for other works by this author on: This Site PubMed Google Scholar Dao-bin Zhou, Dao-bin Zhou Peking Union Medical College Hospital, Chinese Academy Medical Society&Peking Union Medical College, Beijing, China Search for other works by this author on: This Site PubMed Google Scholar Lu Zhang, Lu Zhang Peking Union Medical College Hospital, Beijing, China * Corresponding Author; email: pumczhanglu@163.com Search for other works by this author on: This Site PubMed Google Scholar Jian Li, Prof Jian Li, Prof Peking Union Medical College Hospital, Chinese Academy Medical Society&Peking Union Medical College, Beijing, China https://orcid.org/0000-0002-4549-0694 Search for other works by this author on: This Site PubMed Google Scholar Blood blood.2023020009. https://doi.org/10.1182/blood.2023020009 Article history Submitted: February 6, 2023 Revision Received: March 9, 2023 Accepted: March 11, 2023 Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Request Permissions Cite Icon Cite Search Site Citation Hao Zhao, Miao-yan Zhang, Kai-ni Shen, Jun Feng, Xin-xin Cao, Ming-hui Duan, Dao-bin Zhou, Lu Zhang, Jian Li; A phase 2 prospective study of bortezomib, cyclophosphamide, and dexamethasone in newly-diagnosed iMCD patients. Blood 2023; blood.2023020009. doi: https://doi.org/10.1182/blood.2023020009 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBlood Search Subjects: Lymphoid Neoplasia This content is only available as a PDF. Copyright © 2023 American Society of Hematology2023 Article PDF first page preview Close Modal You do not currently have access to this content. Sign in via your Institution

Utilizing Handoff Reporting Tools to Improve the Novice Nurse's Workflow.

The novice nurse is task oriented and requires guidance to recognize connections in clinical practice. Novice nurses must learn to prioritize, organize, and differentiate between information that is "nice-to-know" versus "need-to-know" to deliver competent nursing care. Nursing literature makes evident that utilizing communication frameworks increases the delivery of clear communication and improves patient outcomes. Novice nurses require a comprehensive handoff-reporting tool to prompt the novice to engage in critical thinking and facilitate communication within their practice.

Romiplostim drug presence in pregnancy and lactation

Letter| February 27, 2023 Romiplostim drug presence in pregnancy and lactation Audrey Ann Labrecque, Audrey Ann Labrecque CHU Sainte-Justine, University of Montreal, Montreal, Quebec, Canada https://orcid.org/0000-0002-7220-7516 Search for other works by this author on: This Site PubMed Google Scholar Steven Roy, Steven Roy University of Calgary, Calgary, Alberta, Canada Search for other works by this author on: This Site PubMed Google Scholar Daniel Young, Daniel Young University of Calgary, Calgary, Canada Search for other works by this author on: This Site PubMed Google Scholar Si An Chen, Si An Chen University of Calgary, Canada Search for other works by this author on: This Site PubMed Google Scholar Laurent Brechenmacher, Laurent Brechenmacher University of Calgary, Calgary, Alberta, Canada Search for other works by this author on: This Site PubMed Google Scholar Doan Le, Doan Le University of Calgary, Calgary, Alberta, Canada Search for other works by this author on: This Site PubMed Google Scholar Stephanie Cooper, Stephanie Cooper University of Calgary, Calgary, Alberta, Canada Search for other works by this author on: This Site PubMed Google Scholar Paul Stephen Gibson, Paul Stephen Gibson University of Calgary, Calgary, Alberta, Canada Search for other works by this author on: This Site PubMed Google Scholar Ann E Clarke, Ann E Clarke University of Calgary, Calgary, Alberta, Canada Search for other works by this author on: This Site PubMed Google Scholar Antoine Dufour, Antoine Dufour University of Calgary, Calgary, Canada https://orcid.org/0000-0002-3429-4188 Search for other works by this author on: This Site PubMed Google Scholar Leslie Skeith Leslie Skeith University of Calgary, Calgary, Canada * Corresponding Author; email: laskeith@ucalgary.ca Search for other works by this author on: This Site PubMed Google Scholar Blood blood.2022019343. https://doi.org/10.1182/blood.2022019343 Article history Submitted: December 6, 2022 Revision Received: January 31, 2023 Accepted: February 2, 2023 Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Request Permissions Cite Icon Cite Search Site Citation Audrey Ann Labrecque, Steven Roy, Daniel Young, Si An Chen, Laurent Brechenmacher, Doan Le, Stephanie Cooper, Paul Stephen Gibson, Ann E Clarke, Antoine Dufour, Leslie Skeith; Romiplostim drug presence in pregnancy and lactation. Blood 2023; blood.2022019343. doi: https://doi.org/10.1182/blood.2022019343 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBlood Search Subjects: Platelets and Thrombopoiesis This content is only available as a PDF. Copyright © 2023 American Society of Hematology2023 Article PDF first page preview Close Modal You do not currently have access to this content. Sign in via your Institution

Novel immunodeficiency caused by homozygous mutation in solute carrier family 19 member 1, which encodes the reduced folate carrier

Letter| February 6, 2023 Novel immunodeficiency caused by homozygous mutation in SLC19A1 encoding the reduced folate carrier Akira Shiraishi, Akira Shiraishi Hospital for Sick Children, Canada https://orcid.org/0000-0003-2184-3587 Search for other works by this author on: This Site PubMed Google Scholar Vedat Uygun, Vedat Uygun Istinye University Faculty of Medicine, Antalya, Turkey https://orcid.org/0000-0003-3257-7798 Search for other works by this author on: This Site PubMed Google Scholar Nigel Sharfe, Nigel Sharfe The Hospital for Sick Children, Toronto, Ontario, Canada Search for other works by this author on: This Site PubMed Google Scholar Serap Beldar, Serap Beldar Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada Search for other works by this author on: This Site PubMed Google Scholar Mark George Ford Sun, Mark George Ford Sun Oracle Therapeutics (Canada) Inc., Toronto, Ontario, Canada Search for other works by this author on: This Site PubMed Google Scholar Harjit Dadi, Harjit Dadi The Hospital for Sick Children, Toronto, Ontario, Canada Search for other works by this author on: This Site PubMed Google Scholar Linda Vong, Linda Vong The Hospital for Sick Children, Toronto, Ontario, Canada Search for other works by this author on: This Site PubMed Google Scholar Michelle Maxson, Michelle Maxson Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada https://orcid.org/0000-0002-1493-490X Search for other works by this author on: This Site PubMed Google Scholar Neslihan E. Karaca, Neslihan E. Karaca Ege University, Izmir, Turkey Search for other works by this author on: This Site PubMed Google Scholar Süleyman Mevlitoğlu, Süleyman Mevlitoğlu Dolunay Pediatric Clinic, Antalya, Turkey Search for other works by this author on: This Site PubMed Google Scholar Sergio Grinstein, Sergio Grinstein The Hospital for Sick Children, Toronto, Canada https://orcid.org/0000-0002-0795-4160 Search for other works by this author on: This Site PubMed Google Scholar Reha Artan, Reha Artan Arkdeniz University Faculty of Medicine, Antalya, Turkey https://orcid.org/0000-0001-6114-9210 Search for other works by this author on: This Site PubMed Google Scholar Daniele Merico, Daniele Merico Vevo Therapeutics, United States https://orcid.org/0000-0002-3728-4401 Search for other works by this author on: This Site PubMed Google Scholar Chaim M Roifman Chaim M Roifman The Hospital for Sick Children, Toronto, Ontario, Canada * Corresponding Author; email: chaim.roifman@sickkids.ca Search for other works by this author on: This Site PubMed Google Scholar Blood blood.2022017968. https://doi.org/10.1182/blood.2022017968 Article history Submitted: September 8, 2022 Revision Received: January 17, 2023 Accepted: January 29, 2023 Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Request Permissions Cite Icon Cite Search Site Citation Akira Shiraishi, Vedat Uygun, Nigel Sharfe, Serap Beldar, Mark George Ford Sun, Harjit Dadi, Linda Vong, Michelle Maxson, Neslihan E. Karaca, Süleyman Mevlitoğlu, Sergio Grinstein, Reha Artan, Daniele Merico, Chaim M Roifman; Novel immunodeficiency caused by homozygous mutation in SLC19A1 encoding the reduced folate carrier. Blood 2023; blood.2022017968. doi: https://doi.org/10.1182/blood.2022017968 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBlood Search Subjects: Immunobiology and Immunotherapy This content is only available as a PDF. Copyright © 2023 American Society of Hematology2023 Article PDF first page preview Close Modal You do not currently have access to this content. Sign in via your Institution

Predictive value of staging PET/CT to detect bone marrow involvement and early outcomes in marginal zone lymphoma

Predictive value of staging PET/CT to detect bone marrow involvement and early outcomes in marginal zone lymphoma

Validation of the Molecular International Prognostic Scoring System in patients with myelodysplastic syndromes

Letter to Blood| April 6, 2023 Validation of the Molecular International Prognostic Scoring System in patients with myelodysplastic syndromes Clinical Trials & Observations Tariq Kewan, Tariq Kewan Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OHDepartment of Hematology and Oncology, Yale University, New Haven, CT https://orcid.org/0000-0003-4651-5125 Search for other works by this author on: This Site PubMed Google Scholar Waled Bahaj, Waled Bahaj Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH Search for other works by this author on: This Site PubMed Google Scholar Arda Durmaz, Arda Durmaz Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OHSystems Biology and Bioinformatics Department, School of Medicine, Case Western Reserve University, Cleveland, OH https://orcid.org/0000-0001-8394-600X Search for other works by this author on: This Site PubMed Google Scholar Mai Aly, Mai Aly Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OHFaculty of Medicine, Assiut University, Assiut, Egypt https://orcid.org/0000-0002-3926-6856 Search for other works by this author on: This Site PubMed Google Scholar Olisaemeka D. Ogbue, Olisaemeka D. Ogbue Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH Search for other works by this author on: This Site PubMed Google Scholar Hetty E. Carraway, Hetty E. Carraway Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH https://orcid.org/0000-0001-5241-3614 Search for other works by this author on: This Site PubMed Google Scholar Mikkael A. Sekeres, Mikkael A. Sekeres Department of Hematology and Oncology, University of Miami, Miami, FL Search for other works by this author on: This Site PubMed Google Scholar Valeria Visconte, Valeria Visconte Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH Search for other works by this author on: This Site PubMed Google Scholar Carmelo Gurnari, Carmelo Gurnari Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OHDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy https://orcid.org/0000-0001-6829-5544 Search for other works by this author on: This Site PubMed Google Scholar Jaroslaw P. Maciejewski Jaroslaw P. Maciejewski Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH Search for other works by this author on: This Site PubMed Google Scholar Blood (2023) 141 (14): 1768–1772. https://doi.org/10.1182/blood.2022018896 Article history Submitted: October 28, 2022 Accepted: January 17, 2023 Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Request Permissions Cite Icon Cite Search Site Citation Tariq Kewan, Waled Bahaj, Arda Durmaz, Mai Aly, Olisaemeka D. Ogbue, Hetty E. Carraway, Mikkael A. Sekeres, Valeria Visconte, Carmelo Gurnari, Jaroslaw P. Maciejewski; Validation of the Molecular International Prognostic Scoring System in patients with myelodysplastic syndromes. Blood 2023; 141 (14): 1768–1772. doi: https://doi.org/10.1182/blood.2022018896 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBlood Search Subjects: Clinical Trials and Observations, Myeloid Neoplasia TO THE EDITOR: Myelodysplastic syndrome (MDS) represents a heterogeneous group of disorders encompassing a wide range of pathologically distinct subtypes associated with different outcomes. Until recently, clinical and cytogenetic features have dominated the pathological classification and the prognostication of MDS.1-3 The wide use of next-generation sequencing and subsequent molecular studies have examined the impact of different genetic alterations on the pathogenetic derivation, diagnostic assignment, and disease prognosis.4-9 The latest contribution to the task of adopting molecular features into the clinical prognostic scheme is represented by the Molecular International Prognostic Scoring System (IPSS-M), a product of the International Working Group for Prognosis in MDS (IWG-PM).10 Here, we took advantage of a large cohort of patients with MDS (n = 1281, supplemental Methods, available on the Blood website) to validate the novel IPSS-M and to compare the score with the...

Monoclonal gammopathy of thrombotic/thrombocytopenic significance

Letter to Blood| April 6, 2023 Monoclonal gammopathy of thrombotic/thrombocytopenic significance Adam J. Kanack, Adam J. Kanack Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN Search for other works by this author on: This Site PubMed Google Scholar Jordan K. Schaefer, Jordan K. Schaefer Department of Medicine, University of Michigan, Ann Arbor, MI https://orcid.org/0000-0002-7166-386X Search for other works by this author on: This Site PubMed Google Scholar Meera Sridharan, Meera Sridharan Department of Medicine, Mayo Clinic, Rochester, MN https://orcid.org/0000-0001-7225-8228 Search for other works by this author on: This Site PubMed Google Scholar Noah P. Splinter, Noah P. Splinter Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN Search for other works by this author on: This Site PubMed Google Scholar Mindy C. Kohlhagen, Mindy C. Kohlhagen Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN Search for other works by this author on: This Site PubMed Google Scholar Bandana Singh, Bandana Singh Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN Search for other works by this author on: This Site PubMed Google Scholar Silvana B. De Lorenzo, Silvana B. De Lorenzo Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN Search for other works by this author on: This Site PubMed Google Scholar Emily E. Mauch, Emily E. Mauch Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN Search for other works by this author on: This Site PubMed Google Scholar Maen A. Hussein, Maen A. Hussein Florida Cancer Specialists, Orlando, FL Search for other works by this author on: This Site PubMed Google Scholar Marwan Shaikh, Marwan Shaikh Department of Medicine, Mayo Clinic, Jacksonville, FL Search for other works by this author on: This Site PubMed Google Scholar Shaji Kumar, Shaji Kumar Department of Medicine, Mayo Clinic, Rochester, MN https://orcid.org/0000-0001-5392-9284 Search for other works by this author on: This Site PubMed Google Scholar Renren Wen, Renren Wen Department of Microbiology and Immunology, Versiti Blood Research Institute and Medical College of Wisconsin, Milwaukee, WI https://orcid.org/0000-0003-2420-8212 Search for other works by this author on: This Site PubMed Google Scholar Demin Wang, Demin Wang Department of Microbiology and Immunology, Versiti Blood Research Institute and Medical College of Wisconsin, Milwaukee, WI https://orcid.org/0000-0001-5549-3795 Search for other works by this author on: This Site PubMed Google Scholar David Murray, David Murray Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN Search for other works by this author on: This Site PubMed Google Scholar Anand Padmanabhan Anand Padmanabhan Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN https://orcid.org/0000-0003-2519-4377 Search for other works by this author on: This Site PubMed Google Scholar Blood (2023) 141 (14): 1772–1776. https://doi.org/10.1182/blood.2022018797 Article history Submitted: October 19, 2022 Accepted: December 27, 2022 Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Request Permissions Cite Icon Cite Search Site Citation Adam J. Kanack, Jordan K. Schaefer, Meera Sridharan, Noah P. Splinter, Mindy C. Kohlhagen, Bandana Singh, Silvana B. De Lorenzo, Emily E. Mauch, Maen A. Hussein, Marwan Shaikh, Shaji Kumar, Renren Wen, Demin Wang, David Murray, Anand Padmanabhan; Monoclonal gammopathy of thrombotic/thrombocytopenic significance. Blood 2023; 141 (14): 1772–1776. doi: https://doi.org/10.1182/blood.2022018797 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBlood Search Subjects: Thrombosis and Hemostasis TO THE EDITOR: Anti–platelet factor 4 (PF4) antibodies have a central role in the pathophysiology of thrombosis and thrombocytopenia in heparin-induced thrombocytopenia (HIT)1,2 and vaccine-induced immune thrombotic thrombocytopenia (VITT).3-7 Here, we present the case of a patient with recurrent thrombosis and thrombocytopenia, secondary to a persistent anti-PF4/polyanion monoclonal antibody due to an underlying neoplastic condition, which we refer to as monoclonal gammopathy of thrombotic/thrombocytopenic significance (MGTS). The implications of these findings for the investigation of unexplained thrombophilia are discussed. A 64-year-old man presented for evaluation of recurrent thrombotic episodes. His medical history included segmental and subsegmental pulmonary emboli, portal vein thrombosis, non-ST elevation myocardial infarction, splenic infarction, and ST elevation myocardial infarction (Figure 1A). Extensive investigations performed did not support a thrombophilia diagnosis (supplemental Table 1 and supplemental Materials; available on the Blood website). His...

Inside front cover

Download options Please wait... Article information DOI https://doi.org/10.1039/D3TB90045B Article type Cover First published 15 Mar 2023 Download Citation J. Mater. Chem. B, 2023,11, 2280-2280 BibTex EndNote MEDLINE ProCite ReferenceManager RefWorks RIS Permissions Request permissions Inside front cover J. Mater. Chem. B, 2023, 11, 2280 DOI: 10.1039/D3TB90045B To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page. If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given. If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page. Read more about how to correctly acknowledge RSC content. Social activity Tweet Share

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Download options Please wait... Article information DOI https://doi.org/10.1039/D3TA90048G Article type Cover First published 14 Mar 2023 Download Citation J. Mater. Chem. A, 2023,11, 5394-5394 BibTex EndNote MEDLINE ProCite ReferenceManager RefWorks RIS Permissions Request permissions Inside front cover J. Mater. Chem. A, 2023, 11, 5394 DOI: 10.1039/D3TA90048G To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page. If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given. If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page. Read more about how to correctly acknowledge RSC content. Social activity Tweet Share

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Download options Please wait... Article information DOI https://doi.org/10.1039/D3QO90023A Article type Cover First published 14 Mar 2023 Download Citation Org. Chem. Front., 2023,10, 1350-1350 BibTex EndNote MEDLINE ProCite ReferenceManager RefWorks RIS Permissions Request permissions Inside front cover Org. Chem. Front., 2023, 10, 1350 DOI: 10.1039/D3QO90023A To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page. If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given. If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page. Read more about how to correctly acknowledge RSC content. Social activity Tweet Share

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Download options Please wait... Article information DOI https://doi.org/10.1039/D3AN90024J Article type Cover First published 13 Mar 2023 Download Citation Analyst, 2023,148, 1387-1388 BibTex EndNote MEDLINE ProCite ReferenceManager RefWorks RIS Permissions Request permissions Back cover Analyst, 2023, 148, 1387 DOI: 10.1039/D3AN90024J To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page. If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given. If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page. Read more about how to correctly acknowledge RSC content. Social activity Tweet Share

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Download options Please wait... Article information DOI https://doi.org/10.1039/D3AY90027D Article type Cover First published 02 Mar 2023 Download Citation Anal. Methods, 2023,15, 1089-1090 BibTex EndNote MEDLINE ProCite ReferenceManager RefWorks RIS Permissions Request permissions Front cover Anal. Methods, 2023, 15, 1089 DOI: 10.1039/D3AY90027D To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page. If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given. If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page. Read more about how to correctly acknowledge RSC content. Social activity Tweet Share

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Download options Please wait... Article information DOI https://doi.org/10.1039/D3QM90022C Article type Cover First published 13 Mar 2023 Download Citation Mater. Chem. Front., 2023,7, 1155-1156 BibTex EndNote MEDLINE ProCite ReferenceManager RefWorks RIS Permissions Request permissions Back cover Mater. Chem. Front., 2023, 7, 1155 DOI: 10.1039/D3QM90022C To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page. If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given. If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page. Read more about how to correctly acknowledge RSC content. Social activity Tweet Share