Basic construction material of such dental constructions is not without well-known disadvantages. Identification of the main reasons for the replacement of complete removable acrylic plate dentures will make it possible to find the most relevant area for development in the field of improvement of this type of prosthetics.AIMS: To assess the reasons for patients' requests for replacement of complete removable acrylic dentures.METHODS: In the period from 2021 to 2022, a comprehensive dental examination of patients with complete absence of teeth who sought dental prosthetic care to replace previously used full removable plate prostheses was carried out, the reasons for the need for a new dental structure of this type and the frequency of their occurrence in the near and distant future were determined. Statistical differences between the indicators were assessed using the nonparametric method of analysis - the χ2 test. In order to assess the risk of a particular cause of referral, relative risk was calculated at 95% confidence interval.RESULTS: The main reason for the patients with complete absence of teeth to replace the operated full removable plate prosthesis in the period up to 3 years is one or another mechanical breakage. After three years of use of this type of dental structure, risk of mechanical failure and functional deficiencies statistically significantly increases by 1.8 and 1.6 times respectively. When prostheses are used for more than 6 years, referrals due to various functional deficiencies begin to dominate the percentage with 58.3%.CONCLUSIONS: The increasing risk of functional defects in the form of impaired fixation and stabilisation makes it necessary to develop a set of measures to prevent the development of atrophic processes in the alveolar bone tissue of the upper and lower jaw alveolar processes, as well as dystrophic changes in the mucous membrane of the denture bed.