This paper presents data on the diversity and distribution of Balkan endemic vascular plants on the Konjuh Mountain in northeastern Bosnia and Herzegovina. Konjuh is characterized by geological heterogeneity and a significant proportion of ophiolitic substrate, which supports the development of endemic-relict serpentinophytes. A total of 31 endemic and four subendemic taxa were recorded in the surveyed area. Among these, Caryophyllaceae, with five recorded endemic taxa, is the most abundant family. The analysis of life forms and chorological spectra showed a dominance of hemicryptophytes and taxa from the South European and Mediterranean-Sub-Mediterranean chorological groups. The majority of endemic and relict taxa in the surveyed area are serpentinophytes. A total of 18 recorded taxa are listed as threatened according to the Red List of Flora of the Federation of Bosnia and Herzegovina. The species findings are presented with a distribution map. The distribution range of endemic and endangered taxa in Konjuh extends beyond the protected area. The results provide a list of locations of particular interest for further research and potential protection due to the diversity of endemic taxa.