PurposeThe purpose of this paper is to explore new ways and lay a solid foundation to solve the problem of reliability growth analysis of major aerospace equipment with various uncertainty data through propose new concepts of general uncertainty data (GUD) and general uncertainty variable (GUV) and build the operation system of GUVs.Design/methodology/approachThe characteristics of reliability growth data of major aerospace equipment and the limitations of current reliability growth models have been analyzed at first. The most commonly used uncertainty system analysis methods of probability statistics, fuzzy mathematics, grey system theory and rough set theory have been introduced. The concepts of GUD and GUV for reliability growth data analysis of major aerospace equipment are proposed. The simplified form of GUV based on the “kernel” and the degree of uncertainty of GUV is defined. Then an operation system of GUVs is built.Findings(1) The concept of GUD; (2) the concept of GUV; (3) The novel operation rules of GUVs with simplified form.Practical implicationsThe method exposed in this paper can be used to integrate complex reliability growth data of major aerospace equipment. The reliability growth models based on GUV can be built for reliability growth evaluation and forecasting of major aerospace equipment in practice. The reliability evaluation example of a solid rocket motor shows that the concept and idea proposed in this paper are feasible. The research of this paper opens up a new way for the analysis of complex uncertainty data of reliability growth of major aerospace equipment. Moreover, the operation of GUVs could be extended to the case of algebraic equation, differential equation and matrix which including GUVs.Originality/valueThe new concepts of GUD and GUV are given for the first time. The novel operation rules of GUVs with simplified form were constructed.